Published in Atherosclerosis on September 02, 2005
Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction. Diabetes (2012) 1.02
The usefulness of circulating adipokine levels for the assessment of obesity-related health problems. Int J Med Sci (2008) 0.99
Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study. PLoS One (2012) 0.99
Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases. Pharmacol Ther (2011) 0.98
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. Biochem J (2006) 0.96
Inhibition of cathepsin S produces neuroprotective effects after traumatic brain injury in mice. Mediators Inflamm (2013) 0.92
Higher cystatin C level predicts long-term mortality in patients with peripheral arterial disease. Atherosclerosis (2011) 0.88
Patient specific proteolytic activity of monocyte-derived macrophages and osteoclasts predicted with temporal kinase activation states during differentiation. Integr Biol (Camb) (2012) 0.86
Serum cathepsin S is associated with decreased insulin sensitivity and the development of type 2 diabetes in a community-based cohort of elderly men. Diabetes Care (2012) 0.86
Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis. J Cell Mol Med (2011) 0.84
Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins. Biol Chem (2012) 0.84
Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease. Am J Cardiol (2008) 0.83
Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications. J Am Soc Nephrol (2015) 0.83
Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms. Future Cardiol (2013) 0.81
Increased serum cathepsin K in patients with coronary artery disease. Yonsei Med J (2014) 0.81
Cysteinyl cathepsins: multifunctional enzymes in cardiovascular disease. Chonnam Med J (2012) 0.80
Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer. Oncotarget (2016) 0.78
Monocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk. Sci Rep (2015) 0.78
Pro-atherogenic shear stress and HIV proteins synergistically upregulate cathepsin K in endothelial cells. Ann Biomed Eng (2014) 0.78
Correlation between serum cathepsin S and insulin resistance in type 2 diabetes. Exp Ther Med (2013) 0.76
Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages. Part Fibre Toxicol (2016) 0.76
Levels of cathepsins in acute myocardial infarction. Indian Heart J (2012) 0.75
Purslane (Portulaca oleracea) Seed Consumption And Aerobic Training Improves Biomarkers Associated with Atherosclerosis in Women with Type 2 Diabetes (T2D). Sci Rep (2016) 0.75
Cathepsin S-Dependent Protease-Activated Receptor-2 Activation: A New Mechanism of Endothelial Dysfunction. J Am Soc Nephrol (2015) 0.75
Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin Zymography. Mol Biotechnol (2016) 0.75
Influence of a prudent diet on circulating cathepsin S in humans. Nutr J (2014) 0.75
Clinical application of simultaneous detection of cystatin C, cathepsin S, and IL-1 in classification of coronary artery disease. J Biomed Res (2017) 0.75
Reduced lopinavir exposure during pregnancy. AIDS (2006) 3.98
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med (2009) 3.97
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature (2008) 3.93
QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations. Bioinformatics (2008) 2.57
Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat Med (2007) 2.54
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest (2003) 2.48
In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. Cell (2006) 2.28
Lysosomal cysteine proteases in atherosclerosis. Arterioscler Thromb Vasc Biol (2004) 2.28
Autophagy regulates ageing in C. elegans. Autophagy (2007) 2.22
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor. Circulation (2007) 2.20
Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques. Circulation (2008) 2.12
Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation (2009) 2.07
Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension (2006) 2.03
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest (2007) 2.00
Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem (2005) 1.79
IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest (2011) 1.77
Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance. EMBO J (2007) 1.76
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res (2012) 1.71
Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J Lipid Res (2011) 1.69
Lopinavir exposure with an increased dose during pregnancy. J Acquir Immune Defic Syndr (2008) 1.65
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol (2008) 1.64
Usefulness of serum tryptase level as an independent biomarker for coronary plaque instability in a Chinese population. Atherosclerosis (2011) 1.64
Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells. Atherosclerosis (2005) 1.59
Enhanced hypertension prevalence in non-Han Chinese minorities from Xinjiang Province, China. Hypertens Res (2009) 1.49
Performance evaluation of a multiplex assay for future use in biomarker discovery efforts to predict body composition. Clin Chem Lab Med (2011) 1.48
Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol (2007) 1.46
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Lopinavir tablet pharmacokinetics with an increased dose during pregnancy. J Acquir Immune Defic Syndr (2010) 1.33
Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice. Circ Res (2005) 1.32
Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice. Circulation (2007) 1.31
Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration. J Am Coll Cardiol (2012) 1.31
Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation (2004) 1.25
Atazanavir pharmacokinetics with and without tenofovir during pregnancy. J Acquir Immune Defic Syndr (2011) 1.24
Attributable risk function in the proportional hazards model for censored time-to-event. Biostatistics (2006) 1.23
Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex. Circ Res (2009) 1.23
Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication. Circulation (2012) 1.23
Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis. Am J Physiol Heart Circ Physiol (2006) 1.22
Effects of natural disasters on conservation policies: the case of the 2008 Wenchuan earthquake, China. Ambio (2011) 1.17
Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils. PLoS One (2011) 1.15
Exercise training stimulates ischemia-induced neovascularization via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age. Circulation (2010) 1.14
Continuous improvement in the immune system of HIV-infected children on prolonged antiretroviral therapy. AIDS (2008) 1.13
Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice. Circulation (2010) 1.11
Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation (2011) 1.11
Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr Rev (2012) 1.11
Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol (2011) 1.11
Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol (2011) 1.09
Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation. Circ Res (2011) 1.08
Directly observed therapy (DOT) for nonadherent HIV-infected youth: lessons learned, challenges ahead. AIDS Res Hum Retroviruses (2010) 1.08
Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer. Cancer Res (2013) 1.08
Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021. Pediatrics (2007) 1.08
Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries. Am J Pathol (2004) 1.07
The immunomodulatory action of sialostatin L on dendritic cells reveals its potential to interfere with autoimmunity. J Immunol (2009) 1.05
Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis. Circulation (2011) 1.05
A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma. Med Oncol (2012) 1.05
Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the β-catenin pathway in hepatic oval cells. PLoS One (2013) 1.05
Do cathepsins play a role in abdominal aortic aneurysm pathogenesis? Ann N Y Acad Sci (2006) 1.03
Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells. PLoS One (2012) 1.02
Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction. Diabetes (2012) 1.02
Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice. Am J Pathol (2010) 1.02
Osteoarthritic change is delayed in a Ctsk-knockout mouse model of osteoarthritis. Arthritis Rheum (2012) 1.00
Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study. PLoS One (2012) 0.99
Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment. Am J Pathol (2008) 0.99
Cathepsins L and S are not required for activation of dipeptidyl peptidase I (cathepsin C) in mice. Biol Chem (2006) 0.99
A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. Cancer Prev Res (Phila) (2010) 0.99
Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases. Pharmacol Ther (2011) 0.98
Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation. Arterioscler Thromb Vasc Biol (2010) 0.97
Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway. Angiogenesis (2012) 0.97
Crystal structures and amidolytic activities of two glycosylated snake venom serine proteinases. J Biol Chem (2005) 0.97
Matricellular protein CCN3 mitigates abdominal aortic aneurysm. J Clin Invest (2016) 0.96
Angiotensin type 1 receptor blocker reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Hypertension (2011) 0.96
p38 MAP kinase plays a functional role in UVB-induced mouse skin carcinogenesis. Mol Carcinog (2011) 0.96
Characterization and expression patterns of a membrane-bound trehalase from Spodoptera exigua. BMC Mol Biol (2008) 0.96
Mast cells and metabolic syndrome. Biochim Biophys Acta (2010) 0.95
Impact of pregnancy on abacavir pharmacokinetics. AIDS (2006) 0.95
Psychological factors, beliefs about medication, and adherence of youth with human immunodeficiency virus in a multisite directly observed therapy pilot study. J Adolesc Health (2010) 0.95
Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers. J Cardiovasc Pharmacol (2009) 0.94
Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions. Cardiovasc Res (2010) 0.94
Mast cells as mediators and modulators of atherogenesis. Circulation (2007) 0.94
Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses. J Immunol (2006) 0.94
Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3. Am J Pathol (2006) 0.93
CD31: beyond a marker for endothelial cells. Cardiovasc Res (2012) 0.92
Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury. Am J Respir Crit Care Med (2007) 0.91
Pre-engraftment syndrome after unrelated donor umbilical cord blood transplantation in patients with hematologic malignancies. Eur J Haematol (2011) 0.91
Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia. Cancer Epidemiol Biomarkers Prev (2011) 0.90
The value of chest tomosynthesis in locating a ground glass nodule (GGN) during endobronchial ultrasonography with a guide sheath: a case report. J Thorac Dis (2013) 0.90