Published in Am J Respir Crit Care Med on August 02, 2007
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Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest (2003) 2.48
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Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol (2007) 2.08
Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation (2009) 2.07
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Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension (2006) 2.03
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest (2007) 2.00
Lysyl oxidase is required for vascular and diaphragmatic development in mice. J Biol Chem (2002) 1.90
Transcriptomic analysis of human lung development. Am J Respir Crit Care Med (2009) 1.87
Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem (2005) 1.79
Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J (2009) 1.79
IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest (2011) 1.77
Increased measurement accuracy for sequence-verified microarray probes. Physiol Genomics (2004) 1.75
Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol (2007) 1.74
Retracted Single autologous stem-cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicenter randomized clinical trial. Blood (2007) 1.73
Urinary biomarkers predict brain tumor presence and response to therapy. Clin Cancer Res (2008) 1.72
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Cardiovasc Res (2012) 1.71
Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J Lipid Res (2011) 1.69
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol (2009) 1.65
Usefulness of serum tryptase level as an independent biomarker for coronary plaque instability in a Chinese population. Atherosclerosis (2011) 1.64
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol (2008) 1.64
Semen parameters and sperm DNA fragmentation as causes of recurrent pregnancy loss. Urology (2011) 1.62
Epithelial cell PPAR[gamma] contributes to normal lung maturation. FASEB J (2006) 1.61
Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells. Atherosclerosis (2005) 1.59
Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease. Am J Physiol Lung Cell Mol Physiol (2004) 1.56
Cardiac myosin-binding protein C: a potential early biomarker of myocardial injury. Basic Res Cardiol (2015) 1.52
Molecular biomarkers for quantitative and discrete COPD phenotypes. Am J Respir Cell Mol Biol (2008) 1.51
Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia. Med Oncol (2012) 1.50
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Enhanced hypertension prevalence in non-Han Chinese minorities from Xinjiang Province, China. Hypertens Res (2009) 1.49
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Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol (2007) 1.46
HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. PLoS Biol (2013) 1.45
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. Am J Respir Crit Care Med (2008) 1.45
A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire. Int J Oncol (2012) 1.44
Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans. J Clin Invest (2011) 1.44
Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases. Am J Pathol (2007) 1.43
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease. J Clin Invest (2013) 1.42
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Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility. Am J Respir Cell Mol Biol (2007) 1.41
FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma. J Allergy Clin Immunol (2007) 1.40
Chromosomal microarray analysis in a girl with mental retardation and spina bifida. Pediatr Neurol (2011) 1.39
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension. Circ Res (2005) 1.37
Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 1.35
Laparoscopic gastric resection for gastrointestinal stromal tumors. Surg Endosc (2008) 1.34
Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium. Arthritis Rheum (2002) 1.34
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. J Virol (2007) 1.33
Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice. Circ Res (2005) 1.32
Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice. Circulation (2007) 1.31
Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and histopathological assessment. J Infect Dis (2005) 1.31
Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration. J Am Coll Cardiol (2012) 1.31
Laparoscopic Dor versus Toupet fundoplication following Heller myotomy for achalasia: results of a multicenter, prospective, randomized-controlled trial. Surg Endosc (2011) 1.27
The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. Diabetes (2012) 1.27
Elastin haploinsufficiency induces alternative aging processes in the aorta. Rejuvenation Res (2008) 1.26
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Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation (2004) 1.25
Oxidative stress and genetic and epidemiologic determinants of oxidant injury in childhood asthma. J Allergy Clin Immunol (2006) 1.25
Increased serum cathepsin S in patients with atherosclerosis and diabetes. Atherosclerosis (2005) 1.24
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages. J Biol Chem (2004) 1.24
Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex. Circ Res (2009) 1.23
Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication. Circulation (2012) 1.23
Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. Am J Respir Cell Mol Biol (2009) 1.22
Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis. Am J Physiol Heart Circ Physiol (2006) 1.22
Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly. J Biol Chem (2005) 1.20
Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation. Am J Respir Cell Mol Biol (2011) 1.19
Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia. Am J Respir Crit Care Med (2012) 1.18
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Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Mol Cancer Res (2007) 1.18
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Discrete contributions of elastic fiber components to arterial development and mechanical compliance. Arterioscler Thromb Vasc Biol (2009) 1.18
The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2010) 1.16
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Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils. PLoS One (2011) 1.15
Exercise training stimulates ischemia-induced neovascularization via phosphatidylinositol 3-kinase/Akt-dependent hypoxia-induced factor-1 alpha reactivation in mice of advanced age. Circulation (2010) 1.14
SERPINB1 upregulation is associated with in vivo complex formation with neutrophil elastase and cathepsin G in a baboon model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol (2006) 1.13
Needle biopsy of incidentally discovered adrenal masses is rarely informative and potentially hazardous. Surgery (2007) 1.13
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Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr Rev (2012) 1.11
Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol (2011) 1.11