Published in J Gene Med on February 01, 2006
Early events in the mammalian response to DNA double-strand breaks. Mutagenesis (2008) 1.33
Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism. Br J Clin Pharmacol (2003) 1.23
The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity. Carcinogenesis (2004) 1.13
Metabolic surgery and cancer: protective effects of bariatric procedures. Cancer (2010) 1.09
In vitro genotoxicity of the West African anti-malarial herbal Cryptolepis sanguinolenta and its major alkaloid cryptolepine. Toxicology (2005) 1.06
Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans. Carcinogenesis (2004) 1.04
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay. Mutat Res (2007) 1.00
Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer. Carcinogenesis (2003) 1.00
Experimental bariatric surgery in rats generates a cytotoxic chemical environment in the gut contents. Front Microbiol (2011) 1.00
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood. Environ Mol Mutagen (2005) 0.95
International Pig-a gene mutation assay trial: evaluation of transferability across 14 laboratories. Environ Mol Mutagen (2011) 0.93
A preliminary evaluation of recombinant adeno-associated virus biodistribution in rhesus monkeys after intrahepatic inoculation in utero. Hum Gene Ther (2002) 0.93
Biomonitoring of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its carcinogenic metabolites in urine. Chem Res Toxicol (2009) 0.91
The cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates the extracellular signal regulated kinase mitogen-activated protein kinase pathway. Cancer Res (2007) 0.90
Titration of non-replicating adenovirus as a vector for transducing active TGF-beta1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice. Int J Exp Pathol (2002) 0.89
Rapid biomonitoring of heterocyclic aromatic amines in human urine by tandem solvent solid phase extraction liquid chromatography electrospray ionization mass spectrometry. Chem Res Toxicol (2004) 0.88
A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine. Chem Res Toxicol (2010) 0.87
The popular herbal antimalarial, extract of Cryptolepis sanguinolenta, is potently cytotoxic. Toxicol Sci (2002) 0.87
An evaluation of chemical photoreactivity and the relationship to phototoxicity. Regul Toxicol Pharmacol (2010) 0.84
Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP 'GreenScreen HC' genotoxicity assay. Mutagenesis (2009) 0.84
Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling. J Proteome Res (2011) 0.84
Mechanisms of induction of cell cycle arrest and cell death by cryptolepine in human lung adenocarcinoma a549 cells. Toxicol Sci (2006) 0.83
The cooked meat derived genotoxic carcinogen 2-amino-3-methylimidazo[4,5-b]pyridine has potent hormone-like activity: mechanistic support for a role in breast cancer. Cancer Res (2007) 0.82
Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians. Chem Res Toxicol (2005) 0.80
The results of five coded compounds: genistein, metaproterenol, rotenone, p-anisidine and resorcinol tested in the pH 6.7 Syrian hamster embryo cell morphological transformation assay. Mutagenesis (2005) 0.80
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells. Toxicology (2010) 0.80
Evaluating the genotoxicity of topoisomerase-targeted antibiotics. Mutagenesis (2011) 0.80
Development and characterization of an in vivo skin photomicronucleus assay in rats. Mutagenesis (2010) 0.79
Are differences in microRNA regulation implicated in species-dependent response to toxicological exposures? Toxicol Sci (2012) 0.79
The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop. Regul Toxicol Pharmacol (2012) 0.79
Evaluation of the Litron In Vitro MicroFlow Kit for the flow cytometric enumeration of micronuclei (MN) in mammalian cells. Mutat Res (2008) 0.78
Biophotonic imaging in HO-1.luc transgenic mice: real-time demonstration of gender-specific chloroform induced renal toxicity. Mutat Res (2005) 0.78
Phytoalexin resveratrol attenuates the mutagenicity of the heterocyclic amines 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.78
Responses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells. Cancer Cell Int (2005) 0.78
Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens. Toxicol Sci (2012) 0.78
The in vivo rat skin photomicronucleus assay: phototoxicity and photogenotoxicity evaluation of six fluoroquinolones. Mutagenesis (2012) 0.77
Mutagenesis by an antisense oligonucleotide and its degradation product. Toxicol Sci (2012) 0.77
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method. Mutat Res (2008) 0.77
Assessment of temporal dose-toxicity relationship of fumed silica nanoparticle in human lung A549 cells by conventional cytotoxicity and ¹H-NMR-based extracellular metabonomic assays. Toxicol Sci (2014) 0.76
A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells. Toxicol In Vitro (2009) 0.76
Time and dose-dependent effects of phenobarbital on the rat liver miRNAome. Toxicology (2013) 0.76
Spontaneous mobilization of integrated recombinant adenoassociated virus in a cell culture model of virus latency. Virology (2002) 0.76
Detecting genotoxic effects of potential clastogens: an in vivo study using the transgenic lacZ plasmid and the MutaMouse model. Mutat Res (2008) 0.76
Evaluating the genetic toxicology of DNA-based products using existing genetic toxicology assays. Mutagenesis (2003) 0.75
Flow cytometric analysis of micronuclei in peripheral blood reticulocytes III. An efficient method of monitoring chromosomal damage in the beagle dog. Toxicol Sci (2007) 0.75
A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation. Mutagenesis (2012) 0.75
GRASr2 evaluation of aliphatic acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances used as flavoring ingredients. J Food Sci (2014) 0.75