PubRank

Brian J Murphy

Author PubWeight™ 22.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science 2002 9.59
2 A novel peroxisome proliferator-activated receptor delta antagonist, SR13904, has anti-proliferative activity in human cancer cells. Cancer Biol Ther 2009 1.47
3 Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. Mol Cell Neurosci 2002 1.10
4 NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biol Chem 2005 1.06
5 Differential profile of CRF receptor distribution in the rat stomach and duodenum assessed by newly developed CRF receptor antibodies. J Neurochem 2004 0.99
6 Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. J Pharmacol Exp Ther 2009 0.85
7 Magnetic resonance imaging measurement of the contralateral normal meniscus is a more accurate method of determining meniscal allograft size than radiographic measurement of the recipient tibial plateau. Arthroscopy 2007 0.83
8 Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin. Clin Cancer Res 2003 0.83
9 Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition. FASEB J 2004 0.83
10 Central G-Protein Coupled Receptors (GPCR)s as molecular targets for the treatment of obesity: assets, liabilities and development status. Curr Drug Targets CNS Neurol Disord 2004 0.83
11 Increase in tissue inhibitor of metalloproteinase-2 (TIMP-2) levels and inhibition of MMP-2 activity in a metastatic breast cancer cell line by an anti-invasive small molecule SR13179. Cancer Lett 2009 0.83
12 Body weight regulation by selective MC4 receptor agonists and antagonists. Ann N Y Acad Sci 2003 0.82
13 Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180). J Med Chem 2007 0.79
14 The metal-responsive transcription factor-1 protein is elevated in human tumors. Cancer Biol Ther 2010 0.77
15 Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists. Bioorg Med Chem Lett 2004 0.77
16 Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate. J Med Chem 2014 0.76
17 Utilization of an active site mutant receptor for the identification of potent and selective atypical 5-HT2C receptor agonists. J Med Chem 2017 0.75
18 Partial peroneus longus tendon rupture in professional basketball players: a report of 2 cases. Am J Orthop (Belle Mead NJ) 2002 0.75
19 (D)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: synthesis and incorporation into the growth hormone secretagogues. Bioorg Med Chem Lett 2008 0.75
20 Discovery, synthesis, and structure-activity studies of tetrazole based growth hormone secretagogues. Bioorg Med Chem Lett 2007 0.75
21 Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties. J Med Chem 2013 0.75
22 Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues. Bioorg Med Chem Lett 2005 0.75
23 Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain. Bioorg Med Chem Lett 2008 0.75
24 Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues. Bioorg Med Chem Lett 2008 0.75
25 Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR). Bioorg Med Chem Lett 2008 0.75
26 Tetrazole based amides as growth hormone secretagogues. Bioorg Med Chem Lett 2008 0.75