Published in Biol Chem on September 01, 2005
The discovery of placenta growth factor and its biological activity. Exp Mol Med (2012) 1.43
Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc. Nucleic Acids Res (2006) 1.14
Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1. Mol Cell Biol (2008) 1.11
Hypoxia increases placenta growth factor expression in human myocardium and cultured neonatal rat cardiomyocytes. J Heart Lung Transplant (2009) 0.91
Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells. BMC Cell Biol (2010) 0.89
Differential regulation of human PlGF gene expression in trophoblast and nontrophoblast cells by oxygen tension. Placenta (2009) 0.89
The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers. Mol Cell Biol (2006) 0.87
Molecular regulation of human placental growth factor (PlGF) gene expression in placental villi and trophoblast cells is mediated via the protein kinase a pathway. Reprod Sci (2010) 0.85
PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge. J Cereb Blood Flow Metab (2011) 0.83
Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. BMC Dev Biol (2008) 0.83
Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide. Microvasc Res (2012) 0.82
Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1). Biochem Cell Biol (2011) 0.79
Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE. Mol Vis (2015) 0.79
Epigenetic control of hypoxia inducible factor-1α-dependent expression of placental growth factor in hypoxic conditions. Epigenetics (2014) 0.79
Arsenite-mediated promotion of anchorage-independent growth of HaCaT cells through placental growth factor. J Invest Dermatol (2014) 0.78
Placenta growth factor and vascular endothelial growth factor a have differential, cell-type specific patterns of expression in vascular cells. Microcirculation (2014) 0.78
Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1α and post-transcriptionally by miR-214 in sickle cell disease. Biochem J (2015) 0.78
The role of small ubiquitin-like modifier-interacting motif in the assembly and regulation of metal-responsive transcription factor 1. J Biol Chem (2011) 0.77
The metal-responsive transcription factor-1 protein is elevated in human tumors. Cancer Biol Ther (2010) 0.77
Maternal and fetoplacental hypoxia do not alter circulating angiogenic growth effectors during human pregnancy. Biol Reprod (2014) 0.75
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell (2006) 8.48
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. Front Biosci (2008) 3.56
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med (2011) 3.31
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? Microbiol Mol Biol Rev (2006) 3.31
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol (2009) 3.26
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nat Med (2002) 2.69
Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. Cell (2010) 2.52
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell (2008) 2.29
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res (2009) 2.22
The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Exp Physiol (2012) 2.20
Moderate altitude but not additional endurance training increases markers of oxidative stress in exhaled breath condensate. Eur J Appl Physiol (2009) 1.99
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Mol Cell (2012) 1.93
Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. J Biol Chem (2005) 1.93
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circ Res (2004) 1.88
Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. Immunity (2002) 1.87
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proc Natl Acad Sci U S A (2011) 1.81
Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. J Biol Chem (2003) 1.79
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Mol Cell Biol (2009) 1.79
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol Cell Biol (2003) 1.75
Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. EMBO J (2004) 1.74
Erythropoietin enhances immune responses in mice. Eur J Immunol (2007) 1.68
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67
PARP1 ADP-ribosylates lysine residues of the core histone tails. Nucleic Acids Res (2010) 1.64
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res (2004) 1.63
SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310. J Cell Sci (2010) 1.60
Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain. J Virol (2002) 1.57
Arginine methylation regulates DNA polymerase beta. Mol Cell (2006) 1.57
Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein. Mol Cell Biol (2003) 1.56
Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. J Physiol (2007) 1.56
Functional NMDA receptors in rat erythrocytes. Am J Physiol Cell Physiol (2010) 1.54
Regulating cellular oxygen sensing by hydroxylation. Cardiovasc Res (2006) 1.54
Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5. EMBO J (2003) 1.53
Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses. Mol Cell (2013) 1.52
A novel peroxisome proliferator-activated receptor delta antagonist, SR13904, has anti-proliferative activity in human cancer cells. Cancer Biol Ther (2009) 1.47
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nat Struct Mol Biol (2013) 1.47
Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. Genes Dev (2005) 1.46
Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models. J Physiol (2011) 1.46
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J (2005) 1.40
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. Eur Heart J (2010) 1.40
PARP-1 and gene regulation: progress and puzzles. Mol Aspects Med (2013) 1.39
Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice. Proc Natl Acad Sci U S A (2009) 1.37
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB J (2003) 1.36
Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression. FASEB J (2002) 1.36
Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci (2009) 1.34
Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J (2003) 1.33
The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells. J Biol Chem (2012) 1.32
The taste of heavy metals: gene regulation by MTF-1. Biochim Biophys Acta (2012) 1.32
Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res (2008) 1.32
DNA looping induced by a transcriptional enhancer in vivo. Nucleic Acids Res (2005) 1.32
A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification. Mol Cell Biol (2006) 1.30
Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res (2005) 1.30
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. Oncogene (2003) 1.30
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain (2011) 1.29
Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration. J Neurosci (2004) 1.27
Differentiating embryonic stem cells into embryoid bodies. Methods Mol Biol (2004) 1.26
Copper homeostasis in eukaryotes: teetering on a tightrope. Biochim Biophys Acta (2006) 1.26
The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. J Mol Biol (2005) 1.25
Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J (2004) 1.25
Histone acetyl transferases: a role in DNA repair and DNA replication. J Mol Med (Berl) (2002) 1.24
HIFs and tumors--causes and consequences. Am J Physiol Regul Integr Comp Physiol (2004) 1.23
Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity. Blood (2003) 1.22
Acetylation regulates the DNA end-trimming activity of DNA polymerase beta. Mol Cell (2002) 1.22
Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circ Res (2011) 1.22
Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast two-hybrid analysis. Mol Cell (2007) 1.22
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor. Cancer Res (2002) 1.20
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors. FASEB J (2002) 1.20
Histone ADP-ribosylation in DNA repair, replication and transcription. Trends Cell Biol (2011) 1.20
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis (2011) 1.19
Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis. Arthritis Rheum (2004) 1.17
Sensing and responding to hypoxia via HIF in model invertebrates. J Insect Physiol (2006) 1.17
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest (2004) 1.17
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. Mol Cell (2012) 1.17
Protein arginine methyltransferase 1 coactivates NF-kappaB-dependent gene expression synergistically with CARM1 and PARP1. J Mol Biol (2008) 1.17
Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation. Int J Biochem Cell Biol (2008) 1.16
Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB J (2009) 1.15
Complete sequence of the 45-kb mouse ribosomal DNA repeat: analysis of the intergenic spacer. Genomics (2003) 1.14
Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcription. J Biol Chem (2002) 1.14
Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc. Nucleic Acids Res (2006) 1.14
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain. Neuroimage (2007) 1.14
Localized insulin-like growth factor I delivery to enhance new bone formation. Bone (2003) 1.12
Rescue of lethal c-KitW/W mice by erythropoietin. Blood (2004) 1.12
Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice. J Physiol (2011) 1.11
The four members of the Drosophila metallothionein family exhibit distinct yet overlapping roles in heavy metal homeostasis and detoxification. Genes Cells (2006) 1.11
Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia. Cell Transplant (2005) 1.11
Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. Mol Cell Neurosci (2002) 1.10
S-glutathionylation of the Na,K-ATPase catalytic α subunit is a determinant of the enzyme redox sensitivity. J Biol Chem (2012) 1.09
Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. J Cereb Blood Flow Metab (2010) 1.08
Macrophages as novel target cells for erythropoietin. Haematologica (2010) 1.08
A recent evolutionary change affects a regulatory element in the human FOXP2 gene. Mol Biol Evol (2012) 1.08