Lihong Chen

Author PubWeight™ 90.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res 2005 3.56
2 VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics. Nucleic Acids Res 2007 3.07
3 Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J Clin Invest 2003 2.87
4 Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol 2006 2.85
5 MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. EMBO J 2005 1.85
6 MDMX regulation of p53 response to ribosomal stress. EMBO J 2006 1.77
7 Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3. EMBO J 2006 1.67
8 Peroxisome proliferator-activated receptor-α is renoprotective in doxorubicin-induced glomerular injury. Kidney Int 2011 1.59
9 ATM activates p53 by regulating MDM2 oligomerization and E3 processivity. EMBO J 2009 1.56
10 Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics 2006 1.54
11 Revisiting the molecular evolutionary history of Shigella spp. J Mol Evol 2006 1.54
12 DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms. Mol Cell Biol 2002 1.53
13 Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting. J Clin Invest 2007 1.45
14 PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells. Biochem Biophys Res Commun 2006 1.42
15 SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 2009 1.33
16 ShiBASE: an integrated database for comparative genomics of Shigella. Nucleic Acids Res 2006 1.31
17 Inhibition of SUV39H1 methyltransferase activity by DBC1. J Biol Chem 2009 1.31
18 Rescue of mutant p53 transcription function by ellipticine. Oncogene 2003 1.14
19 Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists. J Med Chem 2009 1.13
20 The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination. BMC Genomics 2007 1.11
21 Overexpression of a wheat aquaporin gene, TaAQP8, enhances salt stress tolerance in transgenic tobacco. Plant Cell Physiol 2012 1.11
22 TaASR1, a transcription factor gene in wheat, confers drought stress tolerance in transgenic tobacco. Plant Cell Environ 2013 1.09
23 Glucose fluctuations in subjects with normal glucose tolerance, impaired glucose regulation and newly diagnosed type 2 diabetes mellitus. Clin Endocrinol (Oxf) 2012 1.07
24 Draft genome of a Brazilian avian-pathogenic Escherichia coli strain and in silico characterization of virulence-related genes. J Bacteriol 2012 1.07
25 Shear stress induces synthetic-to-contractile phenotypic modulation in smooth muscle cells via peroxisome proliferator-activated receptor alpha/delta activations by prostacyclin released by sheared endothelial cells. Circ Res 2009 1.07
26 Overexpression of the wheat aquaporin gene, TaAQP7, enhances drought tolerance in transgenic tobacco. PLoS One 2012 1.06
27 The complete sequence and analysis of the large virulence plasmid pSS of Shigella sonnei. Plasmid 2005 1.03
28 Transcriptional profiles of the response to ketoconazole and amphotericin B in Trichophyton rubrum. Antimicrob Agents Chemother 2006 1.02
29 Microsomal prostaglandin e2 synthase-1 modulates the response to vascular injury. Circulation 2011 1.01
30 Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats. BMC Pharmacol 2004 1.00
31 Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage. Mol Cell Biol 2011 1.00
32 PPARgamma agonists do not directly enhance basal or insulin-stimulated Na(+) transport via the epithelial Na(+) channel. Pflugers Arch 2005 1.00
33 Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene. Bioorg Med Chem Lett 2010 0.99
34 Inhibition of p53 DNA binding function by the MDM2 protein acidic domain. J Biol Chem 2011 0.99
35 Complete genome sequence of Haemophilus parasuis SH0165. J Bacteriol 2008 0.98
36 Dynamic changes in matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 levels during wound healing in diabetic rats. J Am Podiatr Med Assoc 2009 0.96
37 Complete genome sequence of the extremophilic Bacillus cereus strain Q1 with industrial applications. J Bacteriol 2008 0.96
38 Quantitative studies on structure-ORAC relationships of anthocyanins from eggplant and radish using 3D-QSAR. Food Chem 2013 0.95
39 Liver X receptor agonist TO-901317 upregulates SCD1 expression in renal proximal straight tubule. Am J Physiol Renal Physiol 2005 0.94
40 Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding. Mol Cell Biol 2012 0.94
41 TaCIPK29, a CBL-interacting protein kinase gene from wheat, confers salt stress tolerance in transgenic tobacco. PLoS One 2013 0.93
42 Effectiveness of the PPARγ agonist, GW570, in liver fibrosis. Inflamm Res 2010 0.92
43 Short hairpin RNA targeting Twist1 suppresses cell proliferation and improves chemosensitivity to cisplatin in HeLa human cervical cancer cells. Oncol Rep 2012 0.90
44 Ectopic expression of wheat TaCIPK14, encoding a calcineurin B-like protein-interacting protein kinase, confers salinity and cold tolerance in tobacco. Physiol Plant 2013 0.89
45 TrED: the Trichophyton rubrum Expression Database. BMC Genomics 2007 0.89
46 Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064. Bioorg Med Chem Lett 2008 0.89
47 Regulation of SirT1-nucleomethylin binding by rRNA coordinates ribosome biogenesis with nutrient availability. Mol Cell Biol 2013 0.89
48 Effects of a PPARgamma agonist, GI262570, on renal filtration fraction and nitric oxide level in conscious rats. J Cardiovasc Pharmacol 2003 0.89
49 Causative species and serotypes of shigellosis in mainland China: systematic review and meta-analysis. PLoS One 2012 0.89
50 Expression, purification, and refolding of a novel immunotoxin containing humanized single-chain fragment variable antibody against CTLA4 and the N-terminal fragment of human perforin. Protein Expr Purif 2006 0.88
51 Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes. Nephrol Dial Transplant 2009 0.88
52 Peroxisome proliferator-activated receptors and renal diseases. Front Biosci (Landmark Ed) 2009 0.88
53 Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats. Am J Physiol Renal Physiol 2008 0.87
54 Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation. Thromb Res 2010 0.87
55 Evaluation of the clinical features of HCC following hepatectomy for different stages of HCC. Hepatogastroenterology 2012 0.85
56 Changes of skeletal muscle adiponectin content in diet-induced insulin resistant rats. Biochem Biophys Res Commun 2006 0.84
57 Galectin-4 serves as a prognostic biomarker for the early recurrence / metastasis of hepatocellular carcinoma. Cancer Sci 2014 0.84
58 Expression of mouse membrane-associated prostaglandin E2 synthase-2 (mPGES-2) along the urogenital tract. Biochim Biophys Acta 2006 0.84
59 Transcutaneous oxygen pressure measurement in diabetic foot ulcers: mean values and cut-point for wound healing. J Wound Ostomy Continence Nurs 2013 0.84
60 FXR agonist activity of conformationally constrained analogs of GW 4064. Bioorg Med Chem Lett 2009 0.83
61 Identification and characterization of simple sequence repeats in the genomes of Shigella species. Gene 2003 0.83
62 Effects of different proportion of carbohydrate in breakfast on postprandial glucose excursion in normal glucose tolerance and impaired glucose regulation subjects. Diabetes Technol Ther 2013 0.83
63 Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. Endocrinology 2008 0.83
64 Angiotensin II regulates collagen metabolism through modulating tissue inhibitor of metalloproteinase-1 in diabetic skin tissues. Diab Vasc Dis Res 2013 0.82
65 MH1 domain of SMAD4 binds N-terminal residues of the homeodomain of Hoxc9. Biochim Biophys Acta 2008 0.82
66 Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. Am J Physiol Endocrinol Metab 2010 0.81
67 PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice. PPAR Res 2008 0.81
68 The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. J Biol Chem 2013 0.81
69 Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064. Bioorg Med Chem Lett 2009 0.80
70 Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene. Bioorg Med Chem Lett 2011 0.80
71 [Association of the cocaine and amphetamine-regulated transcript gene with type 2 diabetes mellitus]. Zhonghua Nei Ke Za Zhi 2002 0.80
72 Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. J Med Chem 2013 0.79
73 Role of site-specific DNA demethylation in TNFα-induced MMP9 expression in keratinocytes. J Mol Endocrinol 2013 0.78
74 High-level expression of a functional humanized anti-CTLA4 single-chain variable fragment antibody in Pichia pastoris. Appl Microbiol Biotechnol 2008 0.78
75 High level expression of His-tagged colicin 5 in E. coli and characterization of its narrow-spectrum bactericidal activity and pore-forming action. Protein Expr Purif 2007 0.78
76 Prevalence of 10 human polyomaviruses in fecal samples from children with acute gastroenteritis: a case-control study. J Clin Microbiol 2013 0.78
77 [Evaluation of three in-vitro refolding methods for human-derived anti-CTLA4 scFv expressed in E. coli]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006 0.77
78 Comparison of the virulence plasmid genomes of two strains of Shigella which lost the ability to bind Congo red. Sci China C Life Sci 2006 0.76
79 Structural and functional analysis of denitrification genes in Pseudomonas stutzeri A1501. Sci China C Life Sci 2005 0.76
80 Proteogenomic Analysis of Trichophyton rubrum Aided by RNA Sequencing. J Proteome Res 2015 0.76
81 Rational method in the repetitive calcium oscillation measurement in wild type human epithelial kidney cells. Cytotechnology 2011 0.76
82 Effect of PGE2 on DA tone by EP4 modulating Kv channels with different oxygen tension between preterm and term. Int J Cardiol 2009 0.75
83 Regulation of basal lateral membrane mobility and permeability to divalent cations by membrane associated-protein kinase C. PLoS One 2013 0.75
84 [The study of in vitro refolding conditions for humanized anti-CTLA4-scFv expressed in E. coli]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2005 0.75
85 Extraction, characterization of components, and potential thermoplastic applications of camelina meal grafted with vinyl monomers. J Agric Food Chem 2012 0.75
86 [Two cases of primary malignant lymphoma of thyroid]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2013 0.75
87 Simultaneous measurements of multiple flow parameters for scramjet characterization using tunable diode-laser sensors. Appl Opt 2011 0.75
88 [Expression and purification of recombinant human cytochrome C in Escherichia coli]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2007 0.75
89 [The Hsp90 inhibitor FW-04-806 suppresses Bcr/Abl-mediated growth of leukemia cells by inhibiting proliferation and inducing apoptosis]. Zhonghua Zhong Liu Za Zhi 2015 0.75
90 Correction to α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions. J Med Chem 2020 0.75
91 [Group-I introns in 18S rDNA of Cenococcum geophilum Fr]. Wei Sheng Wu Xue Bao 2012 0.75
92 Biothermoplastics from hydrolyzed and citric acid crosslinked chicken feathers. Mater Sci Eng C Mater Biol Appl 2012 0.75
93 Cilostazol Can Increase Skin Oxygen Supply Assessed by Transcutaneous Oxygen Pressure Measurement in Type 2 Diabetes With Lower Limb Ischemic Disease: A Randomized Trial. J Wound Ostomy Continence Nurs 2016 0.75
94 MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. Medicine (Baltimore) 2017 0.75
95 [Study on expression of cell cycle-related genes in subclonal cell lines of human cervical carcinoma]. Zhonghua Fu Chan Ke Za Zhi 2002 0.75