Published in Genetics on September 01, 2005
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell (2008) 1.80
Insights into the influence of nucleotides on actin family proteins from seven structures of Arp2/3 complex. Mol Cell (2007) 1.70
Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol (2008) 1.50
The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation. Curr Biol (2009) 1.33
Regulation of N-WASP and the Arp2/3 complex by Abp1 controls neuronal morphology. PLoS One (2007) 1.26
Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife (2013) 1.18
Mechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coronin. J Biol Chem (2011) 1.10
Actin and endocytosis in budding yeast. Genetics (2015) 0.99
Polarized growth in the absence of F-actin in Saccharomyces cerevisiae exiting quiescence. PLoS One (2008) 0.97
btn1 affects endocytosis, polarization of sterol-rich membrane domains and polarized growth in Schizosaccharomyces pombe. Traffic (2008) 0.94
Interaction of the endocytic scaffold protein Pan1 with the type I myosins contributes to the late stages of endocytosis. Mol Biol Cell (2007) 0.93
Visualizing the functional architecture of the endocytic machinery. Elife (2015) 0.93
The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation. J Biol Chem (2010) 0.90
Insertions within the actin core of actin-related protein 3 (Arp3) modulate branching nucleation by Arp2/3 complex. J Biol Chem (2012) 0.82
Coronin is a component of the endocytic collar of hyphae of Neurospora crassa and is necessary for normal growth and morphogenesis. PLoS One (2012) 0.81
Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis. PLoS One (2013) 0.78
Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex. Nat Commun (2016) 0.75
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast (1998) 48.29
Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments. J Cell Biol (1986) 7.79
A pathway for association of receptors, adaptors, and actin during endocytic internalization. Cell (2003) 6.27
Crystal structure of Arp2/3 complex. Science (2001) 5.51
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. J Cell Biol (1994) 4.61
Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat Cell Biol (2001) 4.38
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr Biol (2001) 4.16
Cellular control of actin nucleation. Annu Rev Cell Dev Biol (2002) 4.16
Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization. Biochemistry (1999) 3.77
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Polymerization of ADP-actin. J Cell Biol (1984) 3.42
The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin. J Cell Biol (2003) 3.40
Interaction of cortactin and N-WASp with Arp2/3 complex. Curr Biol (2002) 3.34
The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol (2003) 3.13
Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton. J Cell Biol (1997) 2.92
Sequences, structural models, and cellular localization of the actin-related proteins Arp2 and Arp3 from Acanthamoeba. J Cell Biol (1995) 2.77
Conformational changes in the Arp2/3 complex leading to actin nucleation. Nat Struct Mol Biol (2004) 2.77
The Saccharomyces cerevisiae actin-related protein Arp2 is involved in the actin cytoskeleton. J Cell Biol (1996) 2.40
Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits. Proc Natl Acad Sci U S A (1999) 2.29
Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. J Cell Biol (2000) 2.15
A role for myosin-I in actin assembly through interactions with Vrp1p, Bee1p, and the Arp2/3 complex. J Cell Biol (2000) 2.13
New yeast actin-like gene required late in the cell cycle. Nature (1992) 2.12
Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor. Mol Cell (2004) 2.12
End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae. Mol Biol Cell (1997) 2.07
Phosphoregulation of Arp2/3-dependent actin assembly during receptor-mediated endocytosis. Nat Cell Biol (2005) 2.06
Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell (2004) 1.94
Evidence for physical and functional interactions among two Saccharomyces cerevisiae SH3 domain proteins, an adenylyl cyclase-associated protein and the actin cytoskeleton. Mol Biol Cell (1997) 1.94
Live cell imaging of the assembly, disassembly, and actin cable-dependent movement of endosomes and actin patches in the budding yeast, Saccharomyces cerevisiae. J Cell Biol (2004) 1.87
Activation of the Arp2/3 complex by the actin filament binding protein Abp1p. J Cell Biol (2001) 1.85
Negative regulation of yeast WASp by two SH3 domain-containing proteins. Curr Biol (2003) 1.78
Pan1p, End3p, and S1a1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis. Mol Cell Biol (2000) 1.76
Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex. Nat Cell Biol (2001) 1.70
Identification of act2, an essential gene in the fission yeast Schizosaccharomyces pombe that encodes a protein related to actin. Proc Natl Acad Sci U S A (1992) 1.67
The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex. Mol Biol Cell (1999) 1.66
ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators. J Biol Chem (2004) 1.53
Dynamics of yeast Myosin I: evidence for a possible role in scission of endocytic vesicles. Curr Biol (2004) 1.47
Identification of functionally important residues of Arp2/3 complex by analysis of homology models from diverse species. J Mol Biol (2004) 1.45
Vacuolar proteases and proteolytic artifacts in Saccharomyces cerevisiae. Methods Enzymol (2002) 1.29
An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast. J Cell Sci (2003) 1.26
Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation. J Biol Chem (2003) 1.20
The Arabidopsis thaliana ACT4/ACT12 actin gene subclass is strongly expressed throughout pollen development. Plant J (1996) 1.20
Modular complexes that regulate actin assembly in budding yeast. Curr Opin Microbiol (2001) 1.13
Purification of yeast actin and actin-associated proteins. Methods Enzymol (2002) 1.07
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions. Mol Biol Cell (2005) 0.94
Purification of glutathione S-transferase fusion proteins from yeast. Methods Enzymol (2002) 0.79
An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
Conformational changes in the Arp2/3 complex leading to actin nucleation. Nat Struct Mol Biol (2004) 2.77
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Actin nucleation and elongation factors: mechanisms and interplay. Curr Opin Cell Biol (2009) 2.27
Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. J Cell Biol (2002) 2.17
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell (2004) 1.94
Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1. Curr Biol (2003) 1.78
Negative regulation of yeast WASp by two SH3 domain-containing proteins. Curr Biol (2003) 1.78
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature (2011) 1.74
Coronin switches roles in actin disassembly depending on the nucleotide state of actin. Mol Cell (2009) 1.69
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments. Mol Biol Cell (2006) 1.62
Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6. J Biol Chem (2005) 1.60
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol (2010) 1.59
Formin proteins: purification and measurement of effects on actin assembly. Methods Enzymol (2006) 1.43
Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem (2007) 1.41
Cofilin cooperates with fascin to disassemble filopodial actin filaments. J Cell Sci (2011) 1.41
The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Curr Biol (2011) 1.39
Formins at a glance. J Cell Sci (2013) 1.34
GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol (2010) 1.33
The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation. Curr Biol (2009) 1.33
Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging. Science (2012) 1.32
Regulation and targeting of the fission yeast formin cdc12p in cytokinesis. Mol Biol Cell (2008) 1.31
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol (2007) 1.29
Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function. Dev Cell (2009) 1.23
The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton. Mol Biol Cell (2003) 1.21
Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo. J Cell Sci (2006) 1.20
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell (2004) 1.18
Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife (2013) 1.18
Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin. Mol Biol Cell (2012) 1.14
The formin Daam1 and fascin directly collaborate to promote filopodia formation. Curr Biol (2013) 1.08
Mechanism and biological role of profilin-Srv2/CAP interaction. J Cell Sci (2007) 1.04
Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor. Mol Biol Cell (2011) 1.04
Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover. J Biol Chem (2009) 1.03
The myosin passenger protein Smy1 controls actin cable structure and dynamics by acting as a formin damper. Dev Cell (2011) 0.99
Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging. Proc Natl Acad Sci U S A (2013) 0.99
GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism. Curr Biol (2013) 0.96
Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis. J Biol Chem (2010) 0.96
Crystal structure of a coiled-coil domain from human ROCK I. PLoS One (2011) 0.95
A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo. Cytoskeleton (Hoboken) (2010) 0.95
Actin filament labels for localizing protein components in large complexes viewed by electron microscopy. RNA (2008) 0.94
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions. Mol Biol Cell (2005) 0.94
Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation. J Cell Biol (2013) 0.93
Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93
Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis. J Biol Chem (2008) 0.92
Critical roles for multiple formins during cardiac myofibril development and repair. Mol Biol Cell (2014) 0.90
Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6. Proc Natl Acad Sci U S A (2012) 0.90
The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation. J Biol Chem (2010) 0.90
Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration. Mol Biol Cell (2014) 0.89
Coronin: the double-edged sword of actin dynamics. Subcell Biochem (2008) 0.89
Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae. Genetics (2006) 0.85
Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking. Cytoskeleton (Hoboken) (2011) 0.84
Drosophila homologues of adenomatous polyposis coli (APC) and the formin diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly. J Biol Chem (2013) 0.78
WASp identity theft by a bacterial effector. Dev Cell (2008) 0.75