Published in Cytoskeleton (Hoboken) on February 01, 2010
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Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin. Mol Biol Cell (2012) 1.14
Actin and endocytosis in budding yeast. Genetics (2015) 0.99
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Arabidopsis actin-depolymerizing factor7 severs actin filaments and regulates actin cable turnover to promote normal pollen tube growth. Plant Cell (2013) 0.87
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Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1. Curr Biol (2003) 1.78
Interactions of Acanthamoeba profilin with actin and nucleotides bound to actin. Biochemistry (1998) 1.78
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Analysis of the function of Spire in actin assembly and its synergy with formin and profilin. Mol Cell (2007) 1.57
Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization. FASEB J (2002) 1.53
In vivo importance of actin nucleotide exchange catalyzed by profilin. J Cell Biol (2000) 1.39
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Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin. Mol Biol Cell (2007) 1.10
Mechanism and biological role of profilin-Srv2/CAP interaction. J Cell Sci (2007) 1.04
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Crystal structure of the actin binding domain of the cyclase-associated protein. Biochemistry (2004) 1.00
Arabidopsis CAP1 - a key regulator of actin organisation and development. J Cell Sci (2007) 0.98
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Chlamydomonas reinhardtii produces a profilin with unusual biochemical properties. J Cell Sci (2001) 0.92
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Structural requirements for thymosin beta4 in its contact with actin. An NMR-analysis of thymosin beta4 mutants in solution and correlation with their biological activity. Eur J Biochem (2000) 0.83
An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
Conformational changes in the Arp2/3 complex leading to actin nucleation. Nat Struct Mol Biol (2004) 2.77
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Actin nucleation and elongation factors: mechanisms and interplay. Curr Opin Cell Biol (2009) 2.27
Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. J Cell Biol (2002) 2.17
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell (2004) 1.94
Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1. Curr Biol (2003) 1.78
Negative regulation of yeast WASp by two SH3 domain-containing proteins. Curr Biol (2003) 1.78
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature (2011) 1.74
Coronin switches roles in actin disassembly depending on the nucleotide state of actin. Mol Cell (2009) 1.69
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments. Mol Biol Cell (2006) 1.62
Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6. J Biol Chem (2005) 1.60
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol (2010) 1.59
Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation. J Neurosci (2011) 1.53
Formin proteins: purification and measurement of effects on actin assembly. Methods Enzymol (2006) 1.43
Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem (2007) 1.41
Cofilin cooperates with fascin to disassemble filopodial actin filaments. J Cell Sci (2011) 1.41
The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Curr Biol (2011) 1.39
Formins at a glance. J Cell Sci (2013) 1.34
The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation. Curr Biol (2009) 1.33
GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol (2010) 1.33
Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging. Science (2012) 1.32
Regulation and targeting of the fission yeast formin cdc12p in cytokinesis. Mol Biol Cell (2008) 1.31
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol (2007) 1.29
Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function. Dev Cell (2009) 1.23
The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton. Mol Biol Cell (2003) 1.21
Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo. J Cell Sci (2006) 1.20
Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife (2013) 1.18
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell (2004) 1.18
Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin. Mol Biol Cell (2012) 1.14
The formin Daam1 and fascin directly collaborate to promote filopodia formation. Curr Biol (2013) 1.08
Dissection of Arp2/3 complex actin nucleation mechanism and distinct roles for its nucleation-promoting factors in Saccharomyces cerevisiae. Genetics (2005) 1.06
Mechanism and biological role of profilin-Srv2/CAP interaction. J Cell Sci (2007) 1.04
Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor. Mol Biol Cell (2011) 1.04
Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover. J Biol Chem (2009) 1.03
The myosin passenger protein Smy1 controls actin cable structure and dynamics by acting as a formin damper. Dev Cell (2011) 0.99
Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging. Proc Natl Acad Sci U S A (2013) 0.99
Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis. J Biol Chem (2010) 0.96
GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism. Curr Biol (2013) 0.96
Crystal structure of a coiled-coil domain from human ROCK I. PLoS One (2011) 0.95
Actin filament labels for localizing protein components in large complexes viewed by electron microscopy. RNA (2008) 0.94
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions. Mol Biol Cell (2005) 0.94
Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation. J Cell Biol (2013) 0.93
Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93
Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis. J Biol Chem (2008) 0.92
Critical roles for multiple formins during cardiac myofibril development and repair. Mol Biol Cell (2014) 0.90
Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6. Proc Natl Acad Sci U S A (2012) 0.90
The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation. J Biol Chem (2010) 0.90
Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration. Mol Biol Cell (2014) 0.89
Coronin: the double-edged sword of actin dynamics. Subcell Biochem (2008) 0.89
Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae. Genetics (2006) 0.85
Cease-fire at the leading edge: new perspectives on actin filament branching, debranching, and cross-linking. Cytoskeleton (Hoboken) (2011) 0.84
Drosophila homologues of adenomatous polyposis coli (APC) and the formin diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly. J Biol Chem (2013) 0.78
Addendum: The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature (2017) 0.75
WASp identity theft by a bacterial effector. Dev Cell (2008) 0.75