Published in Cytoskeleton (Hoboken) on October 28, 2011
Visualization of uncorrelated, tandem symmetry mismatches in the internal genome packaging apparatus of bacteriophage T7. Proc Natl Acad Sci U S A (2013) 1.19
Novel roles for actin in mitochondrial fission. J Cell Sci (2014) 1.08
Connecting the cytoskeleton to the endoplasmic reticulum and Golgi. Curr Biol (2014) 0.97
Self-organization of protrusions and polarity during eukaryotic chemotaxis. Curr Opin Cell Biol (2014) 0.94
UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex. PLoS Genet (2012) 0.88
Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins. Cytoskeleton (Hoboken) (2015) 0.83
Distributed actin turnover in the lamellipodium and FRAP kinetics. Biophys J (2013) 0.83
Controlling the cortical actin motor. Protoplasma (2012) 0.79
Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions. Am J Physiol Gastrointest Liver Physiol (2015) 0.76
Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin. J Mol Biol (2016) 0.75
Recent advances in understanding Listeria monocytogenes infection: the importance of subcellular and physiological context. F1000Res (2017) 0.75
Cellular motility driven by assembly and disassembly of actin filaments. Cell (2003) 26.05
Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu Rev Biophys Biomol Struct (2000) 10.11
The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci U S A (1998) 9.33
Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature (1999) 8.61
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
Actin microfilament dynamics in locomoting cells. Nature (1991) 8.03
Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility. J Cell Biol (1997) 7.10
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell (2002) 6.80
A modular design for the clathrin- and actin-mediated endocytosis machinery. Cell (2005) 6.70
Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation. J Cell Biol (1997) 6.67
Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex. Curr Biol (1999) 6.24
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature (1992) 5.84
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex. Proc Natl Acad Sci U S A (1999) 5.62
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J Cell Biol (2006) 5.54
Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol (2003) 5.06
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J (1997) 5.03
Actin-binding protein requirement for cortical stability and efficient locomotion. Science (1992) 4.66
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis. Cell (2004) 4.01
Cofilin promotes rapid actin filament turnover in vivo. Nature (1997) 3.99
Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces. Proc Natl Acad Sci U S A (2004) 3.89
Negative regulation of fibroblast motility by Ena/VASP proteins. Cell (2000) 3.89
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Mol Biol Cell (2004) 3.15
Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast. J Cell Biol (1999) 3.03
Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. PLoS Biol (2007) 3.01
The structural basis of actin filament branching by the Arp2/3 complex. J Cell Biol (2008) 2.82
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77
VASP dynamics during lamellipodia protrusion. Nat Cell Biol (1999) 2.70
Formin leaky cap allows elongation in the presence of tight capping proteins. Curr Biol (2003) 2.69
A role for actin arcs in the leading-edge advance of migrating cells. Nat Cell Biol (2011) 2.68
A biomimetic motility assay provides insight into the mechanism of actin-based motility. J Cell Biol (2003) 2.67
The mechanochemistry of endocytosis. PLoS Biol (2009) 2.60
Resemblance of actin-binding protein/actin gels to covalently crosslinked networks. Nature (1990) 2.58
Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks. Curr Biol (2000) 2.51
Arp2/3 ATP hydrolysis-catalysed branch dissociation is critical for endocytic force generation. Nat Cell Biol (2006) 2.48
Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol (2011) 2.48
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol (2001) 2.29
Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia. Cell (2008) 2.28
Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat Cell Biol (2002) 2.27
VASP is a processive actin polymerase that requires monomeric actin for barbed end association. J Cell Biol (2010) 2.13
Electron tomography reveals unbranched networks of actin filaments in lamellipodia. Nat Cell Biol (2010) 2.02
Cofilin dissociates Arp2/3 complex and branches from actin filaments. Curr Biol (2009) 1.98
Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation. EMBO J (2008) 1.90
Diffusing wave spectroscopy microrheology of actin filament networks. Biophys J (1999) 1.77
In silico reconstitution of actin-based symmetry breaking and motility. PLoS Biol (2009) 1.66
The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover: pH sensitivity of F-actin binding by human ADF, but not of Acanthamoeba actophorin. Eur J Biochem (1998) 1.59
F-actin binding is essential for coronin 1B function in vivo. J Cell Sci (2007) 1.55
Comparison of filamin A-induced cross-linking and Arp2/3 complex-mediated branching on the mechanics of actin filaments. J Biol Chem (2002) 1.51
Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC. Oncogene (2010) 1.50
GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol (2010) 1.33
Molecular mechanism of Ena/VASP-mediated actin-filament elongation. EMBO J (2011) 1.30
The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis. J Immunol (2009) 1.27
Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization. Circ Res (2006) 1.16
The formin-homology-domain-containing protein FHOD1 enhances cell migration. J Cell Sci (2003) 1.13
Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc Natl Acad Sci U S A (2010) 1.10
An open model of actin dendritic nucleation. Biophys J (2009) 1.05
GMF is an evolutionarily developed Adf/cofilin-super family protein involved in the Arp2/3 complex-mediated organization of the actin cytoskeleton. Cytoskeleton (Hoboken) (2010) 1.04
Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods. J Cell Biol (1995) 1.04
Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol (2010) 1.01
Functional synergy of actin filament cross-linking proteins. J Biol Chem (2002) 0.95
Visualizing branched actin filaments in lamellipodia by electron tomography. Nat Cell Biol (2011) 0.93
Discussing the morphology of actin filaments in lamellipodia. Trends Cell Biol (2011) 0.89
Arp2/3 ATP hydrolysis: to branch or to debranch? Nat Cell Biol (2006) 0.79
An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52
Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. Cell (2003) 3.92
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
Distinguishing inchworm and hand-over-hand processive kinesin movement by neck rotation measurements. Science (2002) 2.77
Conformational changes in the Arp2/3 complex leading to actin nucleation. Nat Struct Mol Biol (2004) 2.77
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77
The yeast actin cytoskeleton: from cellular function to biochemical mechanism. Microbiol Mol Biol Rev (2006) 2.55
Imaging of single-molecule translocation through nuclear pore complexes. Proc Natl Acad Sci U S A (2004) 2.43
Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J (2008) 2.30
Ordered and dynamic assembly of single spliceosomes. Science (2011) 2.27
Actin nucleation and elongation factors: mechanisms and interplay. Curr Opin Cell Biol (2009) 2.27
FMNL2 drives actin-based protrusion and migration downstream of Cdc42. Curr Biol (2012) 2.18
Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin. J Cell Biol (2002) 2.17
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
Actin and septin ultrastructures at the budding yeast cell cortex. Mol Biol Cell (2004) 1.94
Viewing dynamic assembly of molecular complexes by multi-wavelength single-molecule fluorescence. Biophys J (2006) 1.85
Forward and reverse motion of single RecBCD molecules on DNA. Biophys J (2004) 1.82
Coordinated regulation of actin filament turnover by a high-molecular-weight Srv2/CAP complex, cofilin, profilin, and Aip1. Curr Biol (2003) 1.78
Negative regulation of yeast WASp by two SH3 domain-containing proteins. Curr Biol (2003) 1.78
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature (2011) 1.74
Coronin switches roles in actin disassembly depending on the nucleotide state of actin. Mol Cell (2009) 1.69
Filopodia: Complex models for simple rods. Int J Biochem Cell Biol (2009) 1.64
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments. Mol Biol Cell (2006) 1.62
Diversity in the rates of transcript elongation by single RNA polymerase molecules. J Biol Chem (2003) 1.60
Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6. J Biol Chem (2005) 1.60
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol (2010) 1.59
Mechanism of transcription initiation at an activator-dependent promoter defined by single-molecule observation. Cell (2012) 1.57
Formin proteins: purification and measurement of effects on actin assembly. Methods Enzymol (2006) 1.43
Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem (2007) 1.41
Cofilin cooperates with fascin to disassemble filopodial actin filaments. J Cell Sci (2011) 1.41
The formin DAD domain plays dual roles in autoinhibition and actin nucleation. Curr Biol (2011) 1.39
Formins at a glance. J Cell Sci (2013) 1.34
GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol (2010) 1.33
The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation. Curr Biol (2009) 1.33
Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging. Science (2012) 1.32
Regulation and targeting of the fission yeast formin cdc12p in cytokinesis. Mol Biol Cell (2008) 1.31
Visualizing the splicing of single pre-mRNA molecules in whole cell extract. RNA (2007) 1.29
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol (2007) 1.29
Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin. EMBO J (2011) 1.28
Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. Mol Cell (2006) 1.26
Interconvertible lac repressor-DNA loops revealed by single-molecule experiments. PLoS Biol (2008) 1.23
Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function. Dev Cell (2009) 1.23
The Saccharomyces cerevisiae calponin/transgelin homolog Scp1 functions with fimbrin to regulate stability and organization of the actin cytoskeleton. Mol Biol Cell (2003) 1.21
Phospholipids regulate localization and activity of mDia1 formin. Eur J Cell Biol (2010) 1.20
Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo. J Cell Sci (2006) 1.20
Viewing single lambda site-specific recombination events from start to finish. EMBO J (2006) 1.19
Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife (2013) 1.18
A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell (2004) 1.18
Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin. Mol Biol Cell (2012) 1.14
The formin Daam1 and fascin directly collaborate to promote filopodia formation. Curr Biol (2013) 1.08
RNA polymerase approaches its promoter without long-range sliding along DNA. Proc Natl Acad Sci U S A (2013) 1.07
Dissection of Arp2/3 complex actin nucleation mechanism and distinct roles for its nucleation-promoting factors in Saccharomyces cerevisiae. Genetics (2005) 1.06
Operator sequence alters gene expression independently of transcription factor occupancy in bacteria. Cell Rep (2012) 1.05
Mechanism and biological role of profilin-Srv2/CAP interaction. J Cell Sci (2007) 1.04
Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Rep (2013) 1.04
Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor. Mol Biol Cell (2011) 1.04
Reconstitution and dissection of the 600-kDa Srv2/CAP complex: roles for oligomerization and cofilin-actin binding in driving actin turnover. J Biol Chem (2009) 1.03
The myosin passenger protein Smy1 controls actin cable structure and dynamics by acting as a formin damper. Dev Cell (2011) 0.99
Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging. Proc Natl Acad Sci U S A (2013) 0.99
Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site. Proc Natl Acad Sci U S A (2013) 0.98
GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism. Curr Biol (2013) 0.96
Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis. J Biol Chem (2010) 0.96
New insights into the spliceosome by single molecule fluorescence microscopy. Curr Opin Chem Biol (2011) 0.95
Crystal structure of a coiled-coil domain from human ROCK I. PLoS One (2011) 0.95
A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo. Cytoskeleton (Hoboken) (2010) 0.95
Actin filament labels for localizing protein components in large complexes viewed by electron microscopy. RNA (2008) 0.94
Structural and functional dissection of the Abp1 ADFH actin-binding domain reveals versatile in vivo adapter functions. Mol Biol Cell (2005) 0.94
Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation. J Cell Biol (2013) 0.93
Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93
Kinetics of Hole Nucleation in Biomembrane Rupture. New J Phys (2011) 0.93
Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis. J Biol Chem (2008) 0.92
Processive movement by a kinesin heterodimer with an inactivating mutation in one head. Biochemistry (2008) 0.92
Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules. EMBO J (2011) 0.91
Critical roles for multiple formins during cardiac myofibril development and repair. Mol Biol Cell (2014) 0.90
The p40/ARPC1 subunit of Arp2/3 complex performs multiple essential roles in WASp-regulated actin nucleation. J Biol Chem (2010) 0.90
Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6. Proc Natl Acad Sci U S A (2012) 0.90
Two distinct modes of processive kinesin movement in mixtures of ATP and AMP-PNP. J Gen Physiol (2007) 0.90
Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration. Mol Biol Cell (2014) 0.89
Coronin: the double-edged sword of actin dynamics. Subcell Biochem (2008) 0.89
Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae. Genetics (2006) 0.85
FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry. Proc Natl Acad Sci U S A (2010) 0.80
Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp. Bioorg Med Chem (2010) 0.79
Drosophila homologues of adenomatous polyposis coli (APC) and the formin diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly. J Biol Chem (2013) 0.78
Crystal structure of an engineered YopM-InlB hybrid protein. BMC Struct Biol (2014) 0.75
WASp identity theft by a bacterial effector. Dev Cell (2008) 0.75