Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
LRP: a multifunctional scavenger and signaling receptor.
|
J Clin Invest
|
2001
|
5.31
|
2
|
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.
|
J Clin Invest
|
2000
|
5.07
|
3
|
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions.
|
Neuron
|
1993
|
3.92
|
4
|
In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella.
|
J Cell Biol
|
1994
|
3.19
|
5
|
39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
|
J Biol Chem
|
1991
|
3.17
|
6
|
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A.
|
J Biol Chem
|
1992
|
2.40
|
7
|
LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation.
|
Cell
|
1995
|
2.37
|
8
|
The mammalian low-density lipoprotein receptor family.
|
Annu Rev Nutr
|
1999
|
2.21
|
9
|
Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2.
|
J Biol Chem
|
2000
|
2.18
|
10
|
Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.
|
J Biol Chem
|
2000
|
2.00
|
11
|
A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein.
|
J Biol Chem
|
1992
|
1.89
|
12
|
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator.
|
Proc Natl Acad Sci U S A
|
1992
|
1.88
|
13
|
Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).
|
J Histochem Cytochem
|
1994
|
1.72
|
14
|
The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism.
|
J Biol Chem
|
2001
|
1.72
|
15
|
The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors.
|
Proc Natl Acad Sci U S A
|
2000
|
1.65
|
16
|
Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein.
|
J Biol Chem
|
1998
|
1.42
|
17
|
Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin.
|
J Biol Chem
|
1995
|
1.41
|
18
|
Enhanced venous thrombus resolution in plasminogen activator inhibitor type-2 deficient mice.
|
J Thromb Haemost
|
2014
|
1.41
|
19
|
The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin.
|
J Cell Biol
|
1990
|
1.40
|
20
|
Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65.
|
J Neurosci
|
2001
|
1.40
|
21
|
The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.
|
J Biol Chem
|
1992
|
1.38
|
22
|
Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability.
|
J Thromb Haemost
|
2005
|
1.35
|
23
|
Lipoprotein lipase induces catabolism of normal triglyceride-rich lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor in vitro. A process facilitated by cell-surface proteoglycans.
|
J Biol Chem
|
1993
|
1.31
|
24
|
Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization.
|
J Clin Invest
|
1997
|
1.31
|
25
|
The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor.
|
J Biol Chem
|
1994
|
1.30
|
26
|
Late effects of treatment in survivors of childhood acute myeloid leukemia.
|
J Clin Oncol
|
2000
|
1.28
|
27
|
Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein.
|
Ann Neurol
|
1995
|
1.23
|
28
|
Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons.
|
J Neurochem
|
1999
|
1.23
|
29
|
Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor.
|
J Biol Chem
|
2000
|
1.21
|
30
|
Glycoprotein 330, a member of the low density lipoprotein receptor family, binds lipoprotein lipase in vitro.
|
J Biol Chem
|
1993
|
1.20
|
31
|
Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein.
|
J Biol Chem
|
1997
|
1.18
|
32
|
Fibulin binds to itself and to the carboxyl-terminal heparin-binding region of fibronectin.
|
J Biol Chem
|
1992
|
1.18
|
33
|
Role of the low density lipoprotein-related protein receptor in mediation of factor VIII catabolism.
|
J Biol Chem
|
1999
|
1.17
|
34
|
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates the cellular internalization and degradation of thrombospondin. A process facilitated by cell-surface proteoglycans.
|
J Biol Chem
|
1995
|
1.17
|
35
|
The very low density lipoprotein receptor mediates the cellular catabolism of lipoprotein lipase and urokinase-plasminogen activator inhibitor type I complexes.
|
J Biol Chem
|
1995
|
1.17
|
36
|
Metabolism of thrombospondin 2. Binding and degradation by 3t3 cells and glycosaminoglycan-variant Chinese hamster ovary cells.
|
J Biol Chem
|
1996
|
1.11
|
37
|
Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues.
|
In Vivo
|
1995
|
1.10
|
38
|
The 39-kDa receptor-associated protein modulates lipoprotein catabolism by binding to LDL receptors.
|
J Biol Chem
|
1995
|
1.10
|
39
|
Glycoprotein 330/low density lipoprotein receptor-related protein-2 mediates endocytosis of low density lipoproteins via interaction with apolipoprotein B100.
|
J Biol Chem
|
1995
|
1.09
|
40
|
Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
|
Biochemistry
|
2001
|
1.08
|
41
|
Tissue factor pathway inhibitor inhibits endothelial cell proliferation via association with the very low density lipoprotein receptor.
|
J Biol Chem
|
2001
|
1.07
|
42
|
The low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor binds and mediates catabolism of bovine milk lipoprotein lipase.
|
J Biol Chem
|
1992
|
1.06
|
43
|
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase.
|
J Biol Chem
|
1993
|
1.05
|
44
|
Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein.
|
J Biol Chem
|
1996
|
1.01
|
45
|
Recognition of alpha 2-macroglobulin by the low density lipoprotein receptor-related protein requires the cooperation of two ligand binding cluster regions.
|
J Biol Chem
|
2001
|
1.00
|
46
|
Association of membrane-bound amyloid precursor protein APP with the apolipoprotein E receptor LRP.
|
Brain Res Mol Brain Res
|
2001
|
0.99
|
47
|
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
|
J Clin Invest
|
1997
|
0.99
|
48
|
Domain structure and interactions of the type I and type II modules in the gelatin-binding region of fibronectin. All six modules are independently folded.
|
J Mol Biol
|
1991
|
0.98
|
49
|
Cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is induced by the C-terminal domain of lipoprotein lipase.
|
J Biol Chem
|
1994
|
0.98
|
50
|
The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor regulates cell surface plasminogen activator activity on human trophoblast cells.
|
J Biol Chem
|
1998
|
0.98
|
51
|
The cellular internalization and degradation of hepatic lipase is mediated by low density lipoprotein receptor-related protein and requires cell surface proteoglycans.
|
J Biol Chem
|
1995
|
0.97
|
52
|
The carboxyl-terminal domain of lipoprotein lipase binds to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and mediates binding of normal very low density lipoproteins to LRP.
|
J Biol Chem
|
1994
|
0.95
|
53
|
Binding and degradation of thrombospondin-1 mediated through heparan sulphate proteoglycans and low-density-lipoprotein receptor-related protein: localization of the functional activity to the trimeric N-terminal heparin-binding region of thrombospondin-1.
|
Biochem J
|
1996
|
0.93
|
54
|
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the receptor-associated protein. An overview.
|
Ann N Y Acad Sci
|
1994
|
0.93
|
55
|
Robinow syndrome: report of two patients with cystic kidney disease.
|
Clin Genet
|
1990
|
0.93
|
56
|
Domain organization of the 39-kDa receptor-associated protein.
|
J Biol Chem
|
1999
|
0.93
|
57
|
Interaction of single-chain urokinase with its receptor induces the appearance and disappearance of binding epitopes within the resultant complex for other cell surface proteins.
|
Blood
|
1996
|
0.92
|
58
|
Functional domains of the very low density lipoprotein receptor: molecular analysis of ligand binding and acid-dependent ligand dissociation mechanisms.
|
J Cell Sci
|
1999
|
0.92
|
59
|
Localization and regulation of the human very low density lipoprotein/apolipoprotein-E receptor: trophoblast expression predicts a role for the receptor in placental lipid transport.
|
Endocrinology
|
1995
|
0.91
|
60
|
An overview of the structure and function of glycoprotein 330, a receptor related to the alpha 2-macroglobulin receptor.
|
Ann N Y Acad Sci
|
1994
|
0.90
|
61
|
Regulation of single chain urokinase binding, internalization, and degradation by a plasminogen activator inhibitor 1-derived peptide.
|
J Biol Chem
|
1997
|
0.90
|
62
|
Kinetics of the conformational alterations associated with nucleophilic modification of alpha 2-macroglobulin.
|
Biochemistry
|
1984
|
0.90
|
63
|
Lipoprotein lipase binds to low density lipoprotein receptors and induces receptor-mediated catabolism of very low density lipoproteins in vitro.
|
J Biol Chem
|
1996
|
0.90
|
64
|
Structural studies of human alpha 2-macroglobulin: concordance between projected views obtained by negative-stain and cryoelectron microscopy.
|
J Struct Biol
|
1991
|
0.89
|
65
|
A unique function for LRP-1: a component of a two-receptor system mediating specific endocytosis of plasma-derived factor V by megakaryocytes.
|
J Thromb Haemost
|
2008
|
0.89
|
66
|
Elevation of LDL receptor-related protein levels via ligand interactions in Alzheimer disease and in vitro.
|
J Neuropathol Exp Neurol
|
2001
|
0.88
|
67
|
The existence of independent domain structures in human Lys77-plasminogen.
|
J Biol Chem
|
1981
|
0.87
|
68
|
Characterization of the reaction of plasmin with alpha 2-macroglobulin: effect of antifibrinolytic agents.
|
Biochemistry
|
1987
|
0.86
|
69
|
Calorimetric evaluation of the existence of separate domains in bovine prothrombin.
|
Biochemistry
|
1981
|
0.86
|
70
|
LRP in Alzheimer's disease: friend or foe?
|
J Clin Invest
|
2000
|
0.85
|
71
|
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor.
|
J Lipid Res
|
1999
|
0.84
|
72
|
Enhancement of the streptokinase-catalyzed activation of human plasminogen by human fibrinogen and its plasminolysis products.
|
Biochemistry
|
1982
|
0.84
|
73
|
Interaction of fibrin with VE-cadherin and anti-inflammatory effect of fibrin-derived fragments.
|
J Thromb Haemost
|
2011
|
0.83
|
74
|
Evidence that the platinum-reactive methionyl residue of the alpha 2-macroglobulin receptor recognition site is not in the carboxyl-terminal receptor binding domain.
|
J Biol Chem
|
1988
|
0.83
|
75
|
Thrombin-induced conformational changes of human alpha 2-macroglobulin: evidence for two functional domains.
|
Biochemistry
|
1985
|
0.83
|
76
|
Meta-[211At]astatobenzylguanidine: further evaluation of a potential therapeutic agent.
|
Int J Cancer
|
1994
|
0.83
|
77
|
Electron microscope studies of human alpha 2-macroglobulin-chymotrypsin complex: demonstration that the two structures assigned to native and proteolyzed alpha 2-macroglobulin represent two views of the proteolyzed molecule.
|
Biochem Biophys Res Commun
|
1989
|
0.83
|
78
|
Three-dimensional structures of the human alpha 2-macroglobulin-methylamine and chymotrypsin complexes.
|
J Struct Biol
|
1993
|
0.82
|
79
|
gp330 on type II pneumocytes mediates endocytosis leading to degradation of pro-urokinase, plasminogen activator inhibitor-1 and urokinase-plasminogen activator inhibitor-1 complex.
|
J Cell Sci
|
1995
|
0.82
|
80
|
Selection of Pseudomonas exotoxin-resistant cells with altered expression of alpha 2MR/LRP.
|
Ann N Y Acad Sci
|
1994
|
0.82
|
81
|
Human T cell responses against the major cysteine proteinase (cruzipain) of Trypanosoma cruzi: role of the multifunctional alpha 2-macroglobulin receptor in antigen presentation by monocytes.
|
Int Immunol
|
1997
|
0.82
|
82
|
Reaction of proteinases with alpha 2-macroglobulin: evidence for alternate reaction pathways in the inhibition of trypsin.
|
Biochemistry
|
1989
|
0.82
|
83
|
Glomerular basement membrane. Studies on its structure and interaction with platelets.
|
J Biol Chem
|
1978
|
0.81
|
84
|
Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1).
|
Genomics
|
1994
|
0.81
|
85
|
Characterization of a protein C activator from the venom of Agkistrodon contortrix contortrix.
|
Biochemistry
|
1988
|
0.81
|
86
|
The apolipoprotein E-dependent low density lipoprotein cholesteryl ester selective uptake pathway in murine adrenocortical cells involves chondroitin sulfate proteoglycans and an alpha 2-macroglobulin receptor.
|
J Biol Chem
|
2001
|
0.81
|
87
|
Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture.
|
FEBS Lett
|
1998
|
0.81
|
88
|
Use of anti-idiotypic antibodies to establish that monoclonal antibody 7H11D6 binds to the alpha 2-macroglobulin receptor recognition site.
|
J Biol Chem
|
1988
|
0.81
|
89
|
Fluorescent probes as a measure of conformational alterations induced by nucleophilic modification and proteolysis of bovine alpha 2-macroglobulin.
|
Biochemistry
|
1984
|
0.80
|
90
|
The carboxy-terminal domain of lipoprotein lipase induces cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
|
Ann N Y Acad Sci
|
1994
|
0.80
|
91
|
Effect of methylamine and plasmin on the conformation of human alpha 2-macroglobulin as revealed by differential scanning calorimetric analysis.
|
Biophys J
|
1984
|
0.80
|
92
|
Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
|
Am J Pathol
|
1994
|
0.79
|
93
|
Regulated expression of the trophoblast alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Differentiation and cAMP modulate protein and mRNA levels.
|
J Biol Chem
|
1992
|
0.79
|
94
|
Inhibitory effect on the lipolysis-stimulated receptor of the 39-kDa receptor-associated protein.
|
J Biol Chem
|
1995
|
0.79
|
95
|
Three lipoprotein receptors and cholesterol in inclusion-body myositis muscle.
|
Neurology
|
2002
|
0.79
|
96
|
Lipoprotein lipase reduces secretion of apolipoprotein E from macrophages.
|
J Biol Chem
|
1997
|
0.79
|
97
|
Anaplastic renal cell carcinoma following neuroblastoma.
|
Med Pediatr Oncol
|
1995
|
0.79
|
98
|
Role of lysine binding regions in the kinetic properties of human plasmin.
|
Biochemistry
|
1981
|
0.78
|
99
|
Structure-function relationships of human alpha 2-macroglobulin. Three-dimensional structures of native alpha 2-macroglobulin and its methylamine and chymotrypsin derivatives.
|
Ann N Y Acad Sci
|
1994
|
0.78
|
100
|
Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.
|
Neuroscience
|
2008
|
0.78
|
101
|
No-carrier-added iodine-131-FIBG: evaluation of an MIBG analog.
|
J Nucl Med
|
1997
|
0.78
|
102
|
Alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Relationship to apolipoprotein E and role in Alzheimer disease senile plaques.
|
Ann N Y Acad Sci
|
1994
|
0.78
|
103
|
Potential roles for the low density lipoprotein receptor family of proteins in implantation and placentation.
|
Ann N Y Acad Sci
|
1994
|
0.77
|
104
|
Purification and properties of a plasminogen activator from cultured rat prostate adenocarcinoma cells.
|
Biochemistry
|
1983
|
0.77
|
105
|
Structure of the tryptic glycopeptide isolated from rabbit transferrin.
|
Biochemistry
|
1979
|
0.77
|
106
|
Conformational changes in an epitope localized to the NH2-terminal region of protein C. Evidence for interaction of protein C domains.
|
J Biol Chem
|
1989
|
0.76
|
107
|
Proteinase-alpha 2 macroglobulin complexes are not increased in plasma of patients with cancer.
|
Int J Cancer
|
1991
|
0.76
|
108
|
Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation.
|
J Biol Chem
|
2001
|
0.75
|
109
|
Enhancement of the streptokinase-induced activation of human plasminogen by human fibrinogen and human fibrinogen fragment D1.
|
Ann N Y Acad Sci
|
1983
|
0.75
|
110
|
Protein C and protein S clinical perspectives.
|
Clin Chim Acta
|
1987
|
0.75
|
111
|
Immunoelectron microscopy studies with a monoclonal antibody directed against a receptor recognition site epitope in human alpha 2-macroglobulin.
|
J Struct Biol
|
1991
|
0.75
|
112
|
Structural studies on rabbit transferrin: isolation and characterization of the glycopeptides.
|
Biochemistry
|
1978
|
0.75
|
113
|
The binding of calcium to bovine factor VII.
|
Arch Biochem Biophys
|
1980
|
0.75
|
114
|
Preliminary Investigations on the Scavenger Receptors of the Amebocyte of the American Horseshoe Crab, Limulus polyphemus.
|
Biol Bull
|
1995
|
0.75
|
115
|
Calorimetric study of the rabbit hepatic galactoside binding protein: effects of calcium and ligands.
|
Biochemistry
|
1981
|
0.75
|
116
|
Intraarticular alpha 2-macroglobulin complexes and proteolytic activity in children with juvenile rheumatoid arthritis.
|
Pediatr Res
|
1993
|
0.75
|
117
|
Dynamic equilibria between subcomponents of C1, the first component of human complement.
|
Mol Immunol
|
1992
|
0.75
|
118
|
The structure of the asparagine-linked carbohydrate unit of rat alpha-lactalbumin.
|
J Biol Chem
|
1980
|
0.75
|
119
|
Estimation of molecular weights of peptides and glycopeptides by thin-layer gel filtration.
|
Anal Biochem
|
1977
|
0.75
|
120
|
The novel three-dimensional structure of native human alpha 2-macroglobulin and comparisons with the structure of the methylamine derivative.
|
J Struct Biol
|
1997
|
0.75
|
121
|
Efficacy of nalbuphine as a parenteral analgesic for the treatment of painful episodes in children with sickle cell disease.
|
J Assoc Acad Minor Phys
|
1990
|
0.75
|
122
|
Structural details of proteinase entrapment by human alpha2-macroglobulin emerge from three-dimensional reconstructions of Fab labeled native, half-transformed, and transformed molecules.
|
J Biol Chem
|
1999
|
0.75
|
123
|
Three-dimensional structure of the human plasmin alpha2-macroglobulin complex.
|
J Struct Biol
|
1998
|
0.75
|