Published in Metab Eng on October 17, 2005
Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data. Mol Syst Biol (2006) 3.04
The Ehrlich pathway for fusel alcohol production: a century of research on Saccharomyces cerevisiae metabolism. Appl Environ Microbiol (2008) 2.53
Shifts in growth strategies reflect tradeoffs in cellular economics. Mol Syst Biol (2009) 2.26
Quantitative analysis of the high temperature-induced glycolytic flux increase in Saccharomyces cerevisiae reveals dominant metabolic regulation. J Biol Chem (2008) 1.00
Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics. PLoS Comput Biol (2012) 0.96
Optimality principles in the regulation of metabolic networks. Metabolites (2012) 0.77
Understanding regulation of metabolism through feasibility analysis. PLoS One (2012) 0.76
Metabolism at evolutionary optimal States. Metabolites (2015) 0.75
The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels. Proc Natl Acad Sci U S A (2007) 2.36
Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards. Anal Biochem (2005) 2.33
Lost in transition: start-up of glycolysis yields subpopulations of nongrowing cells. Science (2014) 1.96
Correcting mass isotopomer distributions for naturally occurring isotopes. Biotechnol Bioeng (2002) 1.90
Quantitative evaluation of intracellular metabolite extraction techniques for yeast metabolomics. Anal Chem (2009) 1.72
Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of (13)C-labeled primary metabolites. FEMS Yeast Res (2005) 1.46
Microbial metabolomics: past, present and future methodologies. Biotechnol Lett (2006) 1.40
Filamentous bulking sludge--a critical review. Water Res (2004) 1.30
Dynamic simulation and metabolic re-design of a branched pathway using linlog kinetics. Metab Eng (2003) 1.29
Malic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export. Appl Environ Microbiol (2008) 1.22
Measuring enzyme activities under standardized in vivo-like conditions for systems biology. FEBS J (2010) 1.21
Development and application of a differential method for reliable metabolome analysis in Escherichia coli. Anal Biochem (2008) 1.20
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. Nat Commun (2010) 1.18
Cumulative bondomers: a new concept in flux analysis from 2D [13C,1H] COSY NMR data. Biotechnol Bioeng (2002) 1.15
Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-labelling data. FEMS Yeast Res (2006) 1.11
Determination of the cytosolic free NAD/NADH ratio in Saccharomyces cerevisiae under steady-state and highly dynamic conditions. Biotechnol Bioeng (2008) 1.11
Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics. Metab Eng (2004) 1.09
Atypical glycolysis in Clostridium thermocellum. Appl Environ Microbiol (2013) 1.08
Quantitative analysis of metabolites in complex biological samples using ion-pair reversed-phase liquid chromatography-isotope dilution tandem mass spectrometry. J Chromatogr A (2008) 1.04
Enzymic analysis of NADPH metabolism in beta-lactam-producing Penicillium chrysogenum: presence of a mitochondrial NADPH dehydrogenase. Metab Eng (2005) 1.04
Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence. FEBS J (2005) 1.03
Genome-derived minimal metabolic models for Escherichia coli MG1655 with estimated in vivo respiratory ATP stoichiometry. Biotechnol Bioeng (2010) 1.03
Effect of iclR and arcA knockouts on biomass formation and metabolic fluxes in Escherichia coli K12 and its implications on understanding the metabolism of Escherichia coli BL21 (DE3). BMC Microbiol (2011) 1.03
Model reduction and a priori kinetic parameter identifiability analysis using metabolome time series for metabolic reaction networks with linlog kinetics. Metab Eng (2008) 1.01
Rapid sampling for analysis of in vivo kinetics using the BioScope: a system for continuous-pulse experiments. Biotechnol Bioeng (2002) 1.01
Scale-down of penicillin production in Penicillium chrysogenum. Biotechnol J (2011) 1.01
Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats. FEMS Yeast Res (2005) 0.99
A new framework for the estimation of control parameters in metabolic pathways using lin-log kinetics. Eur J Biochem (2004) 0.99
Dynamics of intracellular metabolites of glycolysis and TCA cycle during cell-cycle-related oscillation in Saccharomyces cerevisiae. Biotechnol Bioeng (2005) 0.97
Sensitivity analysis of a biofilm model describing a one-stage completely autotrophic nitrogen removal (CANON) process. Biotechnol Bioeng (2002) 0.97
Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae. Metab Eng (2010) 0.97
13C-labeled gluconate tracing as a direct and accurate method for determining the pentose phosphate pathway split ratio in Penicillium chrysogenum. Appl Environ Microbiol (2006) 0.97
A comprehensive method for the quantification of the non-oxidative pentose phosphate pathway intermediates in Saccharomyces cerevisiae by GC-IDMS. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.96
Dynamics of glycolytic regulation during adaptation of Saccharomyces cerevisiae to fermentative metabolism. Appl Environ Microbiol (2008) 0.94
Control of the glycolytic flux in Saccharomyces cerevisiae grown at low temperature: a multi-level analysis in anaerobic chemostat cultures. J Biol Chem (2007) 0.94
Simultaneous quantification of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry. Anal Biochem (2009) 0.94
Intracellular metabolite determination in the presence of extracellular abundance: Application to the penicillin biosynthesis pathway in Penicillium chrysogenum. Biotechnol Bioeng (2010) 0.94
The mathematics of metabolic control analysis revisited. Metab Eng (2002) 0.93
An in vivo data-driven framework for classification and quantification of enzyme kinetics and determination of apparent thermodynamic data. Metab Eng (2011) 0.93
Fumaric acid production by fermentation. Appl Microbiol Biotechnol (2008) 0.93
Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum. Metabolomics (2011) 0.92
Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses. Biotechnol Bioeng (2004) 0.92
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics. BMC Bioinformatics (2006) 0.92
Development of quantitative metabolomics for Pichia pastoris. Metabolomics (2011) 0.91
Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation. Biotechnol Bioeng (2003) 0.91
In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope. Metab Eng (2006) 0.91
An engineered yeast efficiently secreting penicillin. PLoS One (2009) 0.90
Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes. Int J Parasitol (2012) 0.90
Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate. FEMS Yeast Res (2009) 0.89