Published in J Cell Biol on October 24, 2005
Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol (2009) 9.56
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Kindlin-2 controls bidirectional signaling of integrins. Genes Dev (2008) 3.15
Molecular architecture and function of matrix adhesions. Cold Spring Harb Perspect Biol (2011) 2.82
Structural basis for the autoinhibition of talin in regulating integrin activation. Mol Cell (2008) 2.53
Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction. Proc Natl Acad Sci U S A (2009) 2.52
Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol (2007) 2.48
Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation. Blood (2013) 1.75
Genetic analysis of beta1 integrin "activation motifs" in mice. J Cell Biol (2006) 1.73
Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. PLoS Comput Biol (2009) 1.69
Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions. Nat Cell Biol (2012) 1.66
Why integrin as a primary target for imaging and therapy. Theranostics (2011) 1.61
Multiscale modeling of form and function. Science (2009) 1.60
New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol (2009) 1.58
Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin. Am J Physiol Cell Physiol (2009) 1.57
How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism. PLoS Comput Biol (2008) 1.53
Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1. J Cell Biol (2008) 1.52
A role for the juxtamembrane cytoplasm in the molecular dynamics of focal adhesions. PLoS One (2009) 1.50
Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation. Proc Natl Acad Sci U S A (2013) 1.44
DEPDC1B coordinates de-adhesion events and cell-cycle progression at mitosis. Dev Cell (2014) 1.43
Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity. J Cell Biol (2008) 1.39
Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review). Mol Membr Biol (2008) 1.39
Distinct recycling of active and inactive β1 integrins. Traffic (2012) 1.38
Spatial organization of adhesion: force-dependent regulation and function in tissue morphogenesis. EMBO J (2010) 1.36
Focal adhesions are sites of integrin extension. J Cell Biol (2010) 1.26
Crawling cells can close wounds without purse strings or signaling. PLoS Comput Biol (2011) 1.26
The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation. J Mol Biol (2009) 1.25
A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion. Cell Res (2012) 1.24
The mechanism of kindlin-mediated activation of integrin αIIbβ3. Curr Biol (2013) 1.22
Quantitative multicolor compositional imaging resolves molecular domains in cell-matrix adhesions. PLoS One (2008) 1.19
Cooperativity in adhesion cluster formation during initial cell adhesion. Biophys J (2008) 1.18
CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts. Mol Biol Cell (2007) 1.13
Structural and biophysical properties of the integrin-associated cytoskeletal protein talin. Biophys Rev (2009) 1.11
Effect of ligand density, receptor density, and nanoparticle size on cell targeting. Nanomedicine (2012) 1.10
Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide. Mol Ther (2009) 1.09
Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1). J Biol Chem (2012) 1.09
Dynamics of cellular focal adhesions on deformable substrates: consequences for cell force microscopy. Biophys J (2008) 1.08
Membrane binding of the N-terminal ubiquitin-like domain of kindlin-2 is crucial for its regulation of integrin activation. Structure (2011) 1.05
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. Elife (2016) 1.04
Mechanisms of talin-dependent integrin signaling and crosstalk. Biochim Biophys Acta (2013) 1.03
Bidirectional control of the inner dynamics of focal adhesions promotes cell migration. Cell Adh Migr (2009) 1.00
Integrin alphaIIbbeta3 activation in Chinese hamster ovary cells and platelets increases clustering rather than affinity. J Biol Chem (2009) 0.97
Computational and experimental models of cancer cell response to fluid shear stress. Front Oncol (2013) 0.95
Sequential binding of αVβ3 and ICAM-1 determines fibrin-mediated melanoma capture and stable adhesion to CD11b/CD18 on neutrophils. J Immunol (2010) 0.95
β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons. Proc Natl Acad Sci U S A (2012) 0.93
Activation of beta 1 but not beta 3 integrin increases cell traction forces. FEBS Lett (2013) 0.92
Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. FEBS J (2013) 0.91
The actin-bundling protein L-plastin supports T-cell motility and activation. Immunol Rev (2013) 0.89
Systems microscopy approaches to understand cancer cell migration and metastasis. Cell Mol Life Sci (2010) 0.89
A spatial model for integrin clustering as a result of feedback between integrin activation and integrin binding. Biophys J (2012) 0.88
Galectin-3- and phospho-caveolin-1-dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells. Mol Biol Cell (2013) 0.88
PIP kinases define PI4,5P₂signaling specificity by association with effectors. Biochim Biophys Acta (2015) 0.88
Localized lipid packing of transmembrane domains impedes integrin clustering. PLoS Comput Biol (2013) 0.88
Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin. Nat Struct Mol Biol (2014) 0.87
Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Dev Cell (2015) 0.86
CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics. Cell Mol Life Sci (2013) 0.86
Leishmania infection modulates beta-1 integrin activation and alters the kinetics of monocyte spreading over fibronectin. Sci Rep (2015) 0.86
Altered expression pattern of integrin alphavbeta3 correlates with actin cytoskeleton in primary cultures of human breast cancer. Cancer Cell Int (2007) 0.85
Nucleation and growth of integrin adhesions. Biophys J (2009) 0.85
Native ligands change integrin sequestering but not oligomerization in raft-mimicking lipid mixtures. Biophys J (2011) 0.85
YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing. J Biol Chem (2016) 0.83
Cooperativity between integrin activation and mechanical stress leads to integrin clustering. Biophys J (2011) 0.83
The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering. PLoS Genet (2014) 0.82
The non-equilibrium thermodynamics and kinetics of focal adhesion dynamics. PLoS One (2010) 0.82
Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact Adhesions. J Neurosci (2016) 0.81
Vestigial is required during late-stage muscle differentiation in Drosophila melanogaster embryos. Mol Biol Cell (2010) 0.81
Fibronectin Mechanobiology Regulates Tumorigenesis. Cell Mol Bioeng (2015) 0.81
β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner. J Cell Biol (2016) 0.81
Probabilistic modeling and analysis of the effects of extra-cellular matrix density on the sizes, shapes, and locations of integrin clusters in adherent cells. BMC Biophys (2011) 0.80
Mechanochemical regulation of growth cone motility. Front Cell Neurosci (2015) 0.80
Spatial organization of cell-adhesive ligands for advanced cell culture. Biotechnol J (2013) 0.80
CW-EPR studies revealed different motional properties and oligomeric states of the integrin β1a transmembrane domain in detergent micelles or liposomes. Sci Rep (2015) 0.80
Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractions. PLoS One (2014) 0.79
Sphingosine kinase-1 associates with integrin {alpha}V{beta}3 to mediate endothelial cell survival. Am J Pathol (2009) 0.78
Mechanosensing can result from adhesion molecule dynamics. Biophys J (2011) 0.78
Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing. J Cell Biol (2014) 0.77
E-cadherin-mediated force transduction signals regulate global cell mechanics. J Cell Sci (2016) 0.77
Sca-1 is involved in the adhesion of myosphere cells to αVβ3 integrin. Biol Open (2012) 0.77
Super-resolution links vinculin localization to function in focal adhesions. Nat Cell Biol (2015) 0.76
Regulation of integrin adhesions by varying the density of substrate-bound epidermal growth factor. Biointerphases (2012) 0.75
ITIH5 mediates epigenetic reprogramming of breast cancer cells. Mol Cancer (2017) 0.75
Myosin phosphorylation on stress fibers predicts contact guidance behavior across diverse breast cancer cells. Biomaterials (2016) 0.75
Structural and mechanical functions of integrins. Biophys Rev (2013) 0.75
Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly. Cell Adh Migr (2016) 0.75
Interface biology of implants. Cell Adh Migr (2009) 0.75
Low affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection. Mol Biol Cell (2017) 0.75
Mechano-Transduction Signals Derived from Self-Assembling Peptide Nanofibers Containing Long Motif of Laminin Influence Neurogenesis in In-Vitro and In-Vivo. Mol Neurobiol (2016) 0.75
Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25
Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science (2001) 8.12
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science (2002) 7.87
Talin binding to integrin beta tails: a final common step in integrin activation. Science (2003) 7.56
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell (2002) 7.03
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science (1995) 6.45
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature (2004) 5.87
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell (1999) 4.98
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J Cell Sci (2003) 4.85
A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. Cell (2002) 4.57
Phosphoinositide regulation of the actin cytoskeleton. Annu Rev Physiol (2002) 4.56
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling. J Biol Chem (1996) 4.45
Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin. Proc Natl Acad Sci U S A (2003) 4.34
Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol (2004) 4.29
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature (2002) 4.03
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol (2003) 3.91
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature (2002) 3.46
GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism. J Cell Biol (2000) 3.46
Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior. J Cell Biol (2001) 3.28
Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations. Science (2003) 3.22
Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion. J Cell Biol (2002) 2.99
The phosphotyrosine binding-like domain of talin activates integrins. J Biol Chem (2002) 2.97
Photobleaching GFP reveals protein dynamics inside live cells. Trends Cell Biol (1999) 2.86
A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation. Science (1990) 2.42
Interference reflection microscopy in cell biology: methodology and applications. J Cell Sci (1985) 2.30
A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol (2004) 2.26
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides. J Biol Chem (2001) 2.25
Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand. J Biol Chem (1999) 2.04
Integrin activation takes shape. J Cell Biol (2002) 2.02
The composition and dynamics of cell-substratum adhesions in locomoting fish keratocytes. J Cell Sci (1997) 2.01
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand. Proc Natl Acad Sci U S A (2003) 1.93
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster. Nat Struct Biol (2003) 1.92
The inner lives of focal adhesions. Trends Cell Biol (2002) 1.92
Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. J Biol Chem (2004) 1.84
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain. J Biol Chem (2001) 1.80
Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells. J Cell Biol (1998) 1.79
Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion. Biochem Soc Trans (2004) 1.74
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain. J Biol Chem (2002) 1.65
Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. J Cell Biol (2003) 1.58
Accumulation of talin in nodes at the edge of the lamellipodium and separate incorporation into adhesion plaques at focal contacts in fibroblasts. J Cell Biol (1991) 1.51
RGD-grafted poly-L-lysine-graft-(polyethylene glycol) copolymers block non-specific protein adsorption while promoting cell adhesion. Biotechnol Bioeng (2003) 1.40
Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain. J Biol Chem (2003) 1.37
Superactivation of integrin alphavbeta3 by low antagonist concentrations. J Cell Sci (2001) 1.28
Fluorescently labeled neomycin as a probe of phosphatidylinositol-4, 5-bisphosphate in membranes. Biochim Biophys Acta (2000) 1.27
5-Bromo-2-deoxyuridine regulates invasiveness and expression of integrins and matrix-degrading proteinases in a differentiated hamster melanoma cell. J Cell Sci (1993) 1.25
Integrin alphaIIb beta3 reconstituted into lipid bilayers is nonclustered in its activated state but clusters after fibrinogen binding. Biochemistry (1997) 1.25
Microcontact printing of novel co-polymers in combination with proteins for cell-biological applications. Biomaterials (2003) 1.25
The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7. J Biol Chem (2004) 1.13
Peptide-specific antibodies localize the major lipid binding sites of talin dimers to oppositely arranged N-terminal 47 kDa subdomains. FEBS Lett (1998) 0.92
Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein. Mol Biol Cell (2003) 3.11
The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat Immunol (2011) 3.04
Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone (2007) 2.33
Podosome and sealing zone: specificity of the osteoclast model. Eur J Cell Biol (2005) 2.20
Cell behaviour on micropatterned substrata: limits of extracellular matrix geometry for spreading and adhesion. J Cell Sci (2004) 2.12
Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood (2009) 2.10
Dual role of macrophages in tumor growth and angiogenesis. J Leukoc Biol (2006) 2.08
Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C. Nature (2004) 1.88
A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. J Cell Sci (2005) 1.87
The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity. J Cell Sci (2003) 1.84
Cell-matrix adhesion complexes: master control machinery of cell migration. Semin Cancer Biol (2007) 1.74
Actin, microtubules and focal adhesion dynamics during cell migration. Int J Biochem Cell Biol (2003) 1.71
Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts. Mol Biol Cell (2003) 1.70
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature (2010) 1.70
Multiscale modeling of form and function. Science (2009) 1.60
New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol (2009) 1.58
Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding. Proc Natl Acad Sci U S A (2003) 1.57
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. J Clin Invest (2005) 1.55
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion. Mol Biol Cell (2005) 1.45
Junctional adhesion molecule a serves as a receptor for prototype and field-isolate strains of mammalian reovirus. J Virol (2005) 1.43
Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol (2005) 1.41
JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood (2007) 1.38
An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features. EMBO Rep (2006) 1.34
Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood (2002) 1.27
JAM family and related proteins in leukocyte migration (Vestweber series). Arterioscler Thromb Vasc Biol (2007) 1.24
Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Cancer Res (2005) 1.23
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism. PLoS One (2011) 1.22
TGFbeta-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels. J Cell Sci (2009) 1.20
Angiogenesis and inflammation face off. Nat Med (2006) 1.20
Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science (2007) 1.14
CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts. Mol Biol Cell (2007) 1.13
Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis. FASEB J (2007) 1.12
Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. Eur J Immunol (2008) 1.12
IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation. Proc Natl Acad Sci U S A (2004) 1.11
Abnormal junctions and permeability of myelin in PMP22-deficient nerves. Ann Neurol (2014) 1.06
JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration. J Biol Chem (2006) 1.05
Matricellular protein CCN1/CYR61: a new player in inflammation and leukocyte trafficking. Semin Immunopathol (2014) 1.04
Expression and function of junctional adhesion molecule-C in human and experimental arthritis. Arthritis Res Ther (2007) 1.03
Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol (2009) 1.03
Integrin-dependent pathologies. J Pathol (2003) 1.02
Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance. J Immunol (2004) 1.01
Molecular identification of distinct neurogenic and melanogenic neural crest sublineages. Development (2003) 1.01
Physiological type I collagen organization induces the formation of a novel class of linear invadosomes. Mol Biol Cell (2011) 1.01
Junctional adhesion molecule-C is a soluble mediator of angiogenesis. J Immunol (2010) 1.00
Neutrophil transmigration under shear flow conditions in vitro is junctional adhesion molecule-C independent. J Immunol (2007) 0.99
Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation. Pigment Cell Melanoma Res (2010) 0.98
Junctional adhesion molecule C mediates leukocyte adhesion to rheumatoid arthritis synovium. Arthritis Rheum (2008) 0.98
The last molecular fortress in leukocyte trans-endothelial migration. Nat Immunol (2002) 0.97
Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report. Arterioscler Thromb Vasc Biol (2009) 0.97
LPS differentially regulates adhesion and transendothelial migration of human monocytes under static and flow conditions. Int Immunol (2007) 0.94
Junctional adhesion molecules and interendothelial junctions. Cells Tissues Organs (2002) 0.93
Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA. J Cell Sci (2012) 0.93
Cutting edge: immediate RANTES secretion by resting memory CD8 T cells following antigenic stimulation. J Immunol (2003) 0.91
A highly specific gold nanoprobe for live-cell single-molecule imaging. Nano Lett (2013) 0.91
JAM-C induces endothelial cell permeability through its association and regulation of {beta}3 integrins. Arterioscler Thromb Vasc Biol (2009) 0.91
Sushi repeat protein X-linked 2, a novel mediator of angiogenesis. FASEB J (2009) 0.90
The endoplasmic reticulum is a key component of the plasma cell death pathway. J Immunol (2006) 0.90
Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion. J Biol Chem (2011) 0.89
The alpha v beta 3 integrin as a tumor homing ligand for lymphocytes. Eur J Immunol (2004) 0.88
Cell surface delivery of the measles virus nucleoprotein: a viral strategy to induce immunosuppression. J Virol (2004) 0.88
Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J (2011) 0.87
A specific endoplasmic reticulum export signal drives transport of stem cell factor (Kitl) to the cell surface. J Biol Chem (2004) 0.87
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα. Cancer Res (2013) 0.87
Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells. Biol Cell (2012) 0.87
A nuclear export signal and phosphorylation regulate Dok1 subcellular localization and functions. Mol Cell Biol (2006) 0.86
Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice. Am J Pathol (2007) 0.86
Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory. J Immunol (2009) 0.86
Vascular and epithelial junctions: a barrier for leucocyte migration. Biochem Soc Trans (2008) 0.86
Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function. J Clin Endocrinol Metab (2005) 0.86
Cooperative expression of junctional adhesion molecule-C and -B supports growth and invasion of glioma. Glia (2010) 0.86
Targeting olfactomedin-like 3 inhibits tumor growth by impairing angiogenesis and pericyte coverage. Mol Cancer Ther (2012) 0.85
Homing of human B cells to lymphoid organs and B-cell lymphoma engraftment are controlled by cell adhesion molecule JAM-C. Cancer Res (2012) 0.85
Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output. Nat Commun (2013) 0.84
Regulatory signals for endothelial podosome formation. Eur J Cell Biol (2008) 0.84
Intracellular interleukin-1 receptor antagonist type 1 antagonizes the stimulatory effect of interleukin-1 alpha precursor on cell motility. Cytokine (2005) 0.84
Forging the endothelium during inflammation: pushing at a half-open door? Cell Tissue Res (2003) 0.84
BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin. Exp Cell Res (2009) 0.83
A complex of synaptic adhesion molecule CADM1, a molecule related to autism spectrum disorder, with MUPP1 in the cerebellum. J Neurochem (2012) 0.82
Cadm1-expressing synapses on Purkinje cell dendrites are involved in mouse ultrasonic vocalization activity. PLoS One (2012) 0.82
Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy. Exp Cell Res (2013) 0.81
Membrane-bound Kit ligand regulates melanocyte adhesion and survival, providing physical interaction with an intraepithelial niche. FASEB J (2012) 0.81
Three-dimensional visualization of the mouse thymus organization in health and immunodeficiency. J Immunol (2012) 0.81
Leukocyte migration to rheumatoid joints: Enzymes take over. Arthritis Rheum (2006) 0.80
Role of interendothelial adhesion molecules in the control of vascular functions. Vascul Pharmacol (2002) 0.80
Lymphocyte transmigration in the brain: a new way of thinking. Nat Immunol (2008) 0.80
Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla. PLoS One (2012) 0.80
Protein conformation as a regulator of cell-matrix adhesion. Phys Chem Chem Phys (2014) 0.79
Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice. PLoS One (2013) 0.78
Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus. PLoS One (2012) 0.78
Urokinase receptor (CD87) clustering in detergent-insoluble adhesion patches leads to cell adhesion independently of integrins. Cell Commun Adhes (2007) 0.78
Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer. FASEB J (2013) 0.78
Involvement of the orphan nuclear estrogen receptor-related receptor α in osteoclast adhesion and transmigration. J Mol Endocrinol (2010) 0.77
Dimerization of Kit-ligand and efficient cell-surface presentation requires a conserved Ser-Gly-Gly-Tyr motif in its transmembrane domain. FASEB J (2009) 0.77
Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing. J Cell Biol (2014) 0.77
Haemangiomas are formed by cells expressing high levels of alphavbeta3 integrin and lacking acetylated LDL uptake. J Pathol (2004) 0.76