Published in EMBO J on August 18, 2010
Spatial organization of the extracellular matrix regulates cell-cell junction positioning. Proc Natl Acad Sci U S A (2012) 1.88
Mechanosensitivity and compositional dynamics of cell-matrix adhesions. EMBO Rep (2013) 1.22
Mechanoinduction of lymph vessel expansion. EMBO J (2011) 1.19
α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction. J Cell Sci (2014) 1.17
α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. J Biol Chem (2012) 1.14
Adherens junctions determine the apical position of the midbody during follicular epithelial cell division. EMBO Rep (2013) 1.09
Dynamic visualization of α-catenin reveals rapid, reversible conformation switching between tension states. Curr Biol (2014) 1.07
A multifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology. PLoS One (2011) 1.04
CCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodeling. J Cell Biol (2013) 1.03
Mechanical force regulates integrin turnover in Drosophila in vivo. Nat Cell Biol (2012) 1.02
Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion. J Cell Biol (2012) 0.98
Cadherin-dependent mechanotransduction depends on ligand identity but not affinity. J Cell Sci (2012) 0.96
Smooth muscle tension induces invasive remodeling of the zebrafish intestine. PLoS Biol (2012) 0.96
Extracellular leucine-rich repeat proteins are required to organize the apical extracellular matrix and maintain epithelial junction integrity in C. elegans. Development (2012) 0.95
Cell division and the maintenance of epithelial order. J Cell Biol (2014) 0.95
Regulation of RhoA activity by adhesion molecules and mechanotransduction. Curr Mol Med (2014) 0.94
E-cadherin-dependent stimulation of traction force at focal adhesions via the Src and PI3K signaling pathways. Biophys J (2012) 0.92
Mechanical state, material properties and continuous description of an epithelial tissue. J R Soc Interface (2012) 0.90
Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex. Dev Cell (2011) 0.90
Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration. Elife (2015) 0.89
Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for α-catenin. PLoS One (2013) 0.89
Mechanosensitive shivering of model tissues under controlled aspiration. Proc Natl Acad Sci U S A (2011) 0.89
Biomimetic emulsions reveal the effect of mechanical forces on cell-cell adhesion. Proc Natl Acad Sci U S A (2012) 0.88
Crossroads of integrins and cadherins in epithelia and stroma remodeling. Cell Adh Migr (2012) 0.88
Actomyosin-based self-organization of cell internalization during C. elegans gastrulation. BMC Biol (2012) 0.87
Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons. Mol Biol Cell (2012) 0.84
Rho GAPs and GEFs: controling switches in endothelial cell adhesion. Cell Adh Migr (2014) 0.82
ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration. J Biol Chem (2011) 0.82
Modulating the actin cytoskeleton affects mechanically induced signal transduction and differentiation in mesenchymal stem cells. PLoS One (2013) 0.82
A hybrid mathematical model for self-organizing cell migration in the zebrafish lateral line. J Math Biol (2014) 0.81
Role of differential adhesion in cell cluster evolution: from vasculogenesis to cancer metastasis. Comput Methods Biomech Biomed Engin (2013) 0.80
Dynamic interactions between the cellular components of the heart and the extracellular matrix. Pflugers Arch (2011) 0.79
Tuning the kinetics of cadherin adhesion. J Invest Dermatol (2013) 0.78
Shear flow-induced formation of tubular cell protrusions in multiple myeloma cells. J Cell Physiol (2011) 0.78
How Tissue Mechanical Properties Affect Enteric Neural Crest Cell Migration. Sci Rep (2016) 0.78
Analysis of cellular behavior and cytoskeletal dynamics reveal a constriction mechanism driving optic cup morphogenesis. Elife (2016) 0.77
Stamping vital cells - a force-based ligand receptor assay. Biophys J (2013) 0.76
In vivo quantitative analysis of Talin turnover in response to force. Mol Biol Cell (2015) 0.76
Defining functional interactions during biogenesis of epithelial junctions. Nat Commun (2016) 0.75
Characterization of partially lifted cell sheets. Tissue Eng Part A (2014) 0.75
The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation. Am J Transl Res (2017) 0.75
Lineage mapper: A versatile cell and particle tracker. Sci Rep (2016) 0.75
Taking cell-matrix adhesions to the third dimension. Science (2001) 15.21
Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74
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Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol (2009) 9.87
Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol (2009) 9.56
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat Cell Biol (2004) 9.31
Deconstructing the cadherin-catenin-actin complex. Cell (2005) 8.39
Stretching single talin rod molecules activates vinculin binding. Science (2009) 8.11
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell (2005) 7.62
Talin binding to integrin beta tails: a final common step in integrin activation. Science (2003) 7.56
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol (1994) 7.53
A genetically encoded photoactivatable Rac controls the motility of living cells. Nature (2009) 7.25
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell (2002) 7.03
Coordination of Rho GTPase activities during cell protrusion. Nature (2009) 6.54
The relationship between force and focal complex development. J Cell Biol (2002) 6.26
Adhesion-dependent cell mechanosensitivity. Annu Rev Cell Dev Biol (2003) 6.08
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature (2004) 5.87
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell (2007) 5.84
Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci (2001) 5.77
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science (2003) 5.58
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J Cell Biol (2006) 5.54
Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev (2006) 5.45
Structural basis of integrin activation by talin. Cell (2007) 5.37
Differential transmission of actin motion within focal adhesions. Science (2007) 5.36
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Pulsed contractions of an actin-myosin network drive apical constriction. Nature (2008) 5.25
Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation. Nature (2004) 5.06
From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol (2008) 5.06
Mechanically activated integrin switch controls alpha5beta1 function. Science (2009) 4.94
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol (1998) 4.91
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J Cell Sci (2003) 4.85
Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol (2002) 4.76
Visualizing the mechanical activation of Src. Nature (2005) 4.63
Lamellipodial actin mechanically links myosin activity with adhesion-site formation. Cell (2007) 4.59
Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med (2008) 4.55
alpha-Catenin as a tension transducer that induces adherens junction development. Nat Cell Biol (2010) 4.42
Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. EMBO J (2000) 4.39
Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol (2000) 4.34
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell (2001) 4.32
Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol (2007) 4.28
Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell (2008) 4.18
Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nat Cell Biol (2001) 4.08
Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells. J Cell Biol (2007) 4.03
Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts. Nat Cell Biol (2000) 3.99
Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure. Cell (2009) 3.92
Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion. J Cell Biol (2007) 3.76
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature (2003) 3.71
Contact inhibition of locomotion in vivo controls neural crest directional migration. Nature (2008) 3.63
Multicellular rosette formation links planar cell polarity to tissue morphogenesis. Dev Cell (2006) 3.52
Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell (2007) 3.52
Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol (2002) 3.49
Myosin II dynamics are regulated by tension in intercalating cells. Dev Cell (2009) 3.49
Cadherin engagement regulates Rho family GTPases. J Biol Chem (2001) 3.47
Mechanical behavior in living cells consistent with the tensegrity model. Proc Natl Acad Sci U S A (2001) 3.47
Mechanical tugging force regulates the size of cell-cell junctions. Proc Natl Acad Sci U S A (2010) 3.44
Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys J (2005) 3.43
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts. Mol Biol Cell (2005) 3.43
Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc Natl Acad Sci U S A (2001) 3.41
Integration of contractile forces during tissue invagination. J Cell Biol (2010) 3.39
Adhesion signaling - crosstalk between integrins, Src and Rho. J Cell Sci (2009) 3.38
Inhibition of RhoA by p120 catenin. Nat Cell Biol (2000) 3.33
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol (2008) 3.29
Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior. J Cell Biol (2001) 3.28
Demonstration of catch bonds between an integrin and its ligand. J Cell Biol (2009) 3.26
Integrin-dependent actomyosin contraction regulates epithelial cell scattering. J Cell Biol (2005) 3.20
ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat Cell Biol (2002) 3.16
Hierarchical assembly of cell-matrix adhesion complexes. Biochem Soc Trans (2004) 3.15
Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity. Proc Natl Acad Sci U S A (2006) 3.15
Kindlin-2 controls bidirectional signaling of integrins. Genes Dev (2008) 3.15
Chemokine signaling mediates self-organizing tissue migration in the zebrafish lateral line. Dev Cell (2006) 3.15
A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat Cell Biol (2003) 3.11
Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A (2008) 3.04
Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol (2004) 3.03
Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol Biol Cell (2004) 2.95
A two-tiered mechanism for stabilization and immobilization of E-cadherin. Nature (2008) 2.89
Kindlin-2 (Mig-2): a co-activator of beta3 integrins. J Cell Biol (2008) 2.88
Force transduction by Triton cytoskeletons. J Cell Biol (2002) 2.83
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt. Proc Natl Acad Sci U S A (2007) 2.82
The extracellular matrix in development and morphogenesis: a dynamic view. Dev Biol (2009) 2.82
Cell migration at a glance. J Cell Sci (2005) 2.80
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76
Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements. Curr Biol (2002) 2.64
The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell (2001) 2.64
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Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev Cell (2005) 2.62
Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability. Curr Biol (2008) 2.59
Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions. Mol Biol Cell (2000) 2.58
The ins and outs of fibronectin matrix assembly. J Cell Sci (2003) 2.58
Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction. Proc Natl Acad Sci U S A (2009) 2.52
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol (1998) 2.52
Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. Nat Cell Biol (2002) 2.50
The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells. J Cell Biol (2005) 2.46
Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol (2010) 2.45
Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J (2000) 2.44
Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell (2004) 2.39
Basal-to-apical cadherin flow at cell junctions. Nat Cell Biol (2006) 2.33
Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Dev Cell (2009) 2.32
Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol (2003) 2.31
The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mech Dev (2003) 2.31
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. J Cell Biol (2008) 2.31
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev Cell (2006) 3.39
Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev Cell (2005) 2.62
Proteomics of early zebrafish embryos. BMC Dev Biol (2006) 2.36
Single-cell force spectroscopy. J Cell Sci (2008) 2.29
Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells. Science (2012) 2.12
The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol (2007) 2.10
A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo. Nat Cell Biol (2009) 2.05
Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biol (2010) 2.03
Forces driving epithelial spreading in zebrafish gastrulation. Science (2012) 1.89
Coordinated cell-shape changes control epithelial movement in zebrafish and Drosophila. Development (2006) 1.76
Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. J Cell Biol (2006) 1.67
Shield formation at the onset of zebrafish gastrulation. Development (2005) 1.52
Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. Curr Biol (2003) 1.50
Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A. Development (2002) 1.48
Quantitative differences in tissue surface tension influence zebrafish germ layer positioning. HFSP J (2008) 1.47
Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development (2003) 1.45
Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci (2005) 1.42
Trafficking and cell migration. Traffic (2009) 1.38
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Movement directionality in collective migration of germ layer progenitors. Curr Biol (2010) 1.33
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The yolk syncytial layer in early zebrafish development. Trends Cell Biol (2010) 1.29
Stereotypical cell division orientation controls neural rod midline formation in zebrafish. Curr Biol (2010) 1.26
Single-cell detection of microRNAs in developing vertebrate embryos after acute administration of a dual-fluorescence reporter/sensor plasmid. Biotechniques (2006) 1.23
Biology and physics of cell shape changes in development. Curr Biol (2009) 1.20
Convergent extension: using collective cell migration and cell intercalation to shape embryos. Development (2012) 1.19
Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly. Nat Cell Biol (2013) 1.18
Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneurones. Development (2005) 1.07
A bond for a lifetime: employing membrane nanotubes from living cells to determine receptor-ligand kinetics. Angew Chem Int Ed Engl (2008) 1.05
Three functions of cadherins in cell adhesion. Curr Biol (2013) 1.03
Identification of regulators of germ layer morphogenesis using proteomics in zebrafish. J Cell Sci (2006) 1.02
Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development (2010) 1.01
Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. Dev Biol (2011) 1.00
Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation. Development (2008) 0.98
Gastrulation dynamics: cells move into focus. Trends Cell Biol (2004) 0.96
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The role of adhesion energy in controlling cell-cell contacts. Curr Opin Cell Biol (2011) 0.93
Control of convergent yolk syncytial layer nuclear movement in zebrafish. Development (2009) 0.90
Defective neuroepithelial cell cohesion affects tangential branchiomotor neuron migration in the zebrafish neural tube. Development (2011) 0.90
Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Dev Biol (2008) 0.87
Lethal giant larvae 2 regulates development of the ciliated organ Kupffer's vesicle. Development (2013) 0.85
Enveloping cell-layer differentiation at the surface of zebrafish germ-layer tissue explants. Proc Natl Acad Sci U S A (2011) 0.85
Cell adhesion in embryo morphogenesis. Curr Opin Cell Biol (2011) 0.83
UV laser ablation to measure cell and tissue-generated forces in the zebrafish embryo in vivo and ex vivo. Methods Mol Biol (2015) 0.82
Adhesive crosstalk in gastrulation. Dev Cell (2003) 0.78
Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. Methods Mol Biol (2009) 0.78
Holding on and letting go: cadherin turnover in cell intercalation. Dev Cell (2013) 0.77
The force and effect of cell proliferation. EMBO J (2013) 0.77
Cell-cell adhesion and extracellular matrix: diversity counts. Curr Opin Cell Biol (2012) 0.77
Probing E-cadherin endocytosis by morpholino-mediated Rab5 knockdown in zebrafish. Methods Mol Biol (2008) 0.76
Neurulation: coordinating cell polarisation and lumen formation. EMBO J (2012) 0.76
Chaos begets order: asynchronous cell contractions drive epithelial morphogenesis. Dev Cell (2009) 0.76
Carl-Philipp Heisenberg: early embryos make a big move. Interview by Caitlin Sedwick. J Cell Biol (2013) 0.75
Spurred by resistance: mechanosensation in collective migration. Dev Cell (2012) 0.75