Published in J Neurochem on November 01, 2005
The inflammatory response in stroke. J Neuroimmunol (2006) 5.33
Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. J Clin Invest (2009) 1.48
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The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp. J Cell Biol (2007) 0.97
Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia. Brain Res (2009) 0.96
Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release. BMC Biochem (2009) 0.94
Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. J Cell Biol (2015) 0.87
Preconditioning neuroprotection in global cerebral ischemia involves NMDA receptor-mediated ERK-JNK3 crosstalk. Neurosci Res (2009) 0.82
Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. J Biol Chem (2011) 0.82
Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders. Curr Opin HIV AIDS (2014) 0.78
A transmissible cytotoxic activity isolated from a patient with brain ischemia causes microglial cell activation and dysfunction. Cell Mol Neurobiol (2007) 0.75
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature (2005) 4.53
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron (2005) 2.07
Upregulation of forebrain NMDA NR2B receptors contributes to behavioral sensitization after inflammation. J Neurosci (2005) 1.87
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis (2012) 1.84
ATM controls meiotic double-strand-break formation. Nature (2011) 1.68
All-trans retinoic acid prevents development of cardiac remodeling in aortic banded rats by inhibiting the renin-angiotensin system. Am J Physiol Heart Circ Physiol (2007) 1.57
Novel small-molecule inhibitors of RNA polymerase III. Eukaryot Cell (2003) 1.56
A nonproton ligand sensor in the acid-sensing ion channel. Neuron (2010) 1.52
Activation of retinoid receptor-mediated signaling ameliorates diabetes-induced cardiac dysfunction in Zucker diabetic rats. J Mol Cell Cardiol (2013) 1.49
Wnt5a enhances the response of CML cells to Imatinib Mesylate through JNK activation and γ-catenin inhibition. Leuk Res (2013) 1.43
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord. J Biol Chem (2004) 1.38
Enhanced contextual fear memory in central serotonin-deficient mice. Proc Natl Acad Sci U S A (2008) 1.31
CNS penetration of intrathecal-lumbar idursulfase in the monkey, dog and mouse: implications for neurological outcomes of lysosomal storage disorder. PLoS One (2012) 1.29
Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cells. J Biol Chem (2002) 1.26
Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized. Mol Cancer (2007) 1.24
Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury. FEBS Lett (2007) 1.18
Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism. PLoS Biol (2009) 1.17
Kinases and kinase signaling pathways: potential therapeutic targets in Parkinson's disease. Prog Neurobiol (2012) 1.16
Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. Proc Natl Acad Sci U S A (2010) 1.15
Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. J Neurosci (2007) 1.15
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci (2011) 1.12
Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury. J Neurochem (2006) 1.11
DNA polymerase beta is critical for mouse meiotic synapsis. EMBO J (2009) 1.09
Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome. Am J Hum Genet (2009) 1.09
Sodium salicylate reduces inhibitory postsynaptic currents in neurons of rat auditory cortex. Hear Res (2006) 1.08
Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis. Brain Res (2006) 1.07
The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation. Brain Res (2005) 1.06
Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval. Cereb Cortex (2008) 1.05
High-content screening moves to the front of the line. Drug Discov Today (2006) 1.05
Impact of high-dose, chemically modified sulfamidase on pathology in a murine model of MPS IIIA. Exp Neurol (2011) 1.04
A population-based study on the risks of cervical lesion and human papillomavirus infection among women in Beijing, People's Republic of China. Cancer Epidemiol Biomarkers Prev (2010) 1.03
CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease. J Neuroinflammation (2011) 1.03
Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury. Cell Signal (2007) 1.03
Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition. Neuropsychopharmacology (2007) 1.03
Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice. Brain (2010) 1.03
MEC-17 deficiency leads to reduced α-tubulin acetylation and impaired migration of cortical neurons. J Neurosci (2012) 1.02
Mitogen-activated protein kinases and mitogen-activated protein kinase phosphatases mediate the inhibitory effects of all-trans retinoic acid on the hypertrophic growth of cardiomyocytes. J Biol Chem (2004) 1.02
Safety evaluation of chronic intrathecal administration of idursulfase-IT in cynomolgus monkeys. Toxicol Pathol (2011) 1.01
All-trans retinoic acid prevents angiotensin II- and mechanical stretch-induced reactive oxygen species generation and cardiomyocyte apoptosis. J Cell Physiol (2008) 1.01
High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. J Cell Physiol (2012) 1.00
Additive neuroprotection of GABA A and GABA B receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade. Neuropharmacology (2008) 1.00
Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats. Pharmacol Biochem Behav (2007) 0.99
GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. J Neurosci (2009) 0.99
Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways. J Biol Chem (2006) 0.99
Bcl6 is required for the development of mouse CD4+ and CD8α+ dendritic cells. J Immunol (2010) 0.98
Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants. Basic Clin Pharmacol Toxicol (2004) 0.98
Acidosis, acid-sensing ion channels, and neuronal cell death. Mol Neurobiol (2011) 0.97
The aspirin metabolite salicylate enhances neuronal excitation in rat hippocampal CA1 area through reducing GABAergic inhibition. Neuropharmacology (2007) 0.97
Down-regulation of PTEN by sodium orthovanadate inhibits ASK1 activation via PI3-K/Akt during cerebral ischemia in rat hippocampus. Neurosci Lett (2006) 0.97
Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin. Cardiovasc Res (2010) 0.97
Properties of the proton-evoked currents and their modulation by Ca2+ and Zn2+ in the acutely dissociated hippocampus CA1 neurons. Brain Res (2004) 0.96
The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells. Int J Mol Med (2010) 0.95
PELP1--a novel estrogen receptor-interacting protein. Mol Cell Endocrinol (2008) 0.95
ASIC3 channels in multimodal sensory perception. ACS Chem Neurosci (2010) 0.95
Preclinical dose ranging studies for enzyme replacement therapy with idursulfase in a knock-out mouse model of MPS II. Mol Genet Metab (2007) 0.95
The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res (2005) 0.94
PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity. J Neurosci (2012) 0.94
Cyr61/CCN1 is regulated by Wnt/β-catenin signaling and plays an important role in the progression of hepatocellular carcinoma. PLoS One (2012) 0.94
Association study of SCARB2 rs6812193 polymorphism with Parkinson's disease in Han Chinese. Neurosci Lett (2012) 0.94
Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus. J Neurochem (2008) 0.93
The actions of propofol on gamma-aminobutyric acid-A and glycine receptors in acutely dissociated spinal dorsal horn neurons of the rat. Anesth Analg (2002) 0.93
Preterm births in countries with a very high human development index. Lancet (2013) 0.93
Acetylation of RNA processing proteins and cell cycle proteins in mitosis. J Proteome Res (2010) 0.93
Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease. CNS Neurosci Ther (2012) 0.93
Calcium-permeable acid-sensing ion channel is a molecular target of the neurotoxic metal ion lead. J Biol Chem (2005) 0.92
Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons. J Biol Chem (2003) 0.92
ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain. Mol Pain (2010) 0.92
Heterogeneity in retinoic acid signaling in neuroblastomas: Role of matrix metalloproteinases in retinoic acid-induced differentiation. Biochim Biophys Acta (2007) 0.92
Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats. Biol Pharm Bull (2007) 0.92
Molecular mechanism of constitutive endocytosis of Acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death. J Neurosci (2013) 0.92
Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride. J Biol Chem (2011) 0.91
Oversulfated chondroitin sulfate is not the sole contaminant in heparin. Nat Biotechnol (2010) 0.91
Retinoic acid receptor-mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: role of the renin-angiotensin system. J Cell Physiol (2011) 0.91
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection. Cell Microbiol (2014) 0.90
Sleep disorders in Chinese patients with Parkinson's disease: validation study of a Chinese version of Parkinson's disease sleep scale. J Neurol Sci (2008) 0.90
New protein kinase C activator regulates amyloid precursor protein processing in vitro by increasing alpha-secretase activity. Eur J Neurosci (2007) 0.90
Neuroprotective effects of preconditioning ischaemia on ischaemic brain injury through inhibition of mixed-lineage kinase 3 via NMDA receptor-mediated Akt1 activation. J Neurochem (2005) 0.90
Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp. Neuron Glia Biol (2006) 0.90
Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation. J Biol Chem (2005) 0.89
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. FASEB J (2012) 0.89
A-type GABA receptor as a central target of TRPM8 agonist menthol. PLoS One (2008) 0.89
Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels. J Biol Chem (2011) 0.89
Retinoic acid protects cardiomyocytes from high glucose-induced apoptosis through inhibition of NF-κB signaling pathway. J Cell Physiol (2013) 0.89
Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence. Brain (2005) 0.89
Retracted Comprehensive gene expression analysis reveals multiple signal pathways associated with prostate cancer. J Appl Genet (2013) 0.88
Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization. EMBO J (2003) 0.88
PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci Lett (2007) 0.88
2-methoxyestradiol attenuates autophagy activation after global ischemia. Can J Neurol Sci (2011) 0.88
Microneedle integrated transdermal patch for fast onset and sustained delivery of lidocaine. Mol Pharm (2013) 0.87
Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia. Neurosci Res (2004) 0.87