Published in Cancer Res on November 01, 2005
The claudin gene family: expression in normal and neoplastic tissues. BMC Cancer (2006) 2.61
Biology of claudins. Am J Physiol Renal Physiol (2008) 2.17
Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. BMC Med Genomics (2009) 1.91
The claudins. Genome Biol (2009) 1.76
Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Lab Invest (2008) 1.64
Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol (2011) 1.45
Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. BMC Cancer (2009) 1.44
Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells. Am J Pathol (2007) 1.41
New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. Am J Surg Pathol (2008) 1.39
Copy number variants at Williams-Beuren syndrome 7q11.23 region. Hum Genet (2010) 1.32
Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis. Proc Natl Acad Sci U S A (2009) 1.28
Role of EMT in Metastasis and Therapy Resistance. J Clin Med (2016) 1.20
Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway. Exp Cell Res (2011) 1.20
Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20
Phosphorylation of claudin-4 by PKCepsilon regulates tight junction barrier function in ovarian cancer cells. Exp Cell Res (2007) 1.12
Smad7 induces hepatic metastasis in colorectal cancer. Br J Cancer (2008) 1.12
The claudin family of proteins in human malignancy: a clinical perspective. Cancer Manag Res (2013) 1.10
Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. PLoS One (2009) 1.10
Modulation of acetylation: creating a pro-survival and anti-inflammatory phenotype in lethal hemorrhagic and septic shock. J Biomed Biotechnol (2011) 1.09
Structural constraints for the binding of short peptides to claudin-4 revealed by surface plasmon resonance. J Biol Chem (2008) 1.09
Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases. Neoplasia (2012) 1.09
Claudin 4 identifies a wide spectrum of epithelial neoplasms and represents a very useful marker for carcinoma versus mesothelioma diagnosis in pleural and peritoneal biopsies and effusions. Virchows Arch (2007) 1.08
PKC and PKA phosphorylation affect the subcellular localization of claudin-1 in melanoma cells. Int J Med Sci (2009) 1.08
Pathogenesis of ovarian cancer: clues from selected overexpressed genes. Future Oncol (2009) 1.08
Emerging roles of claudins in human cancer. Int J Mol Sci (2013) 1.05
Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1. PLoS One (2009) 1.04
FACS-assisted microarray profiling implicates novel genes and pathways in zebrafish gastrointestinal tract development. Gastroenterology (2009) 1.04
Claudin-3 and claudin-4 expression in serous papillary, clear-cell, and endometrioid endometrial cancer. Gynecol Oncol (2008) 1.04
Tight junctions: a barrier to the initiation and progression of breast cancer? J Biomed Biotechnol (2009) 1.01
Anti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cells. Clin Cancer Res (2008) 1.00
Claudins: control of barrier function and regulation in response to oxidant stress. Antioxid Redox Signal (2011) 1.00
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Claudin 1 in breast tumorigenesis: revelation of a possible novel "claudin high" subset of breast cancers. J Biomed Biotechnol (2010) 0.98
Claudins 1, 3, and 4 protein expression in ER negative breast cancer correlates with markers of the basal phenotype. Virchows Arch (2009) 0.96
Claudin expression in high-grade invasive ductal carcinoma of the breast: correlation with the molecular subtype. Mod Pathol (2012) 0.96
Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis. PLoS One (2009) 0.95
Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: implications for non-small cell lung cancer tumor colonization. Mol Carcinog (2009) 0.95
Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am J Pathol (2010) 0.95
Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications. Carcinogenesis (2010) 0.95
Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer. Clin Exp Metastasis (2008) 0.94
Claudin-11 is over-expressed and dislocated from the blood-testis barrier in Sertoli cells associated with testicular intraepithelial neoplasia in men. Histochem Cell Biol (2009) 0.94
Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease. Virchows Arch (2010) 0.93
Claudin-1, -2, -3, -4, -7, -8, and -10 protein expression in biliary tract cancers. J Histochem Cytochem (2008) 0.93
Use of Clostridium perfringens Enterotoxin and the Enterotoxin Receptor-Binding Domain (C-CPE) for Cancer Treatment: Opportunities and Challenges. J Toxicol (2011) 0.92
Age-related changes of claudin expression in mouse liver, kidney, and pancreas. J Gerontol A Biol Sci Med Sci (2009) 0.92
Creating a pro-survival and anti-inflammatory phenotype by modulation of acetylation in models of hemorrhagic and septic shock. Adv Exp Med Biol (2012) 0.92
Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis. BMC Cancer (2007) 0.92
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer. PLoS One (2012) 0.91
[6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- κ B/Snail Signal Transduction Pathway. Evid Based Complement Alternat Med (2013) 0.91
Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion. PLoS One (2011) 0.91
Identification of novel neuroendocrine-specific tumour genes. Br J Cancer (2008) 0.91
Claudin 4 Is differentially expressed between ovarian cancer subtypes and plays a role in spheroid formation. Int J Mol Sci (2011) 0.91
C terminus of Clostridium perfringens enterotoxin downregulates CLDN4 and sensitizes ovarian cancer cells to Taxol and Carboplatin. Clin Cancer Res (2010) 0.91
Clostridium perfringens enterotoxin interacts with claudins via electrostatic attraction. J Biol Chem (2009) 0.91
On the interaction of Clostridium perfringens enterotoxin with claudins. Toxins (Basel) (2010) 0.90
Establishment and characterization of a new drug surviving cell line Am1010, derived directly from muscle metastases of a human lung adenocarcinoma patient with multi-drug-resistance to cisplatin, taxol, and gefitinib. Acta Pharmacol Sin (2010) 0.90
Expression transformation of claudin-1 in the process of gastric adenocarcinoma invasion. World J Gastroenterol (2008) 0.90
Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy. Int J Mol Sci (2013) 0.89
Claudins in renal physiology and disease. Pediatr Nephrol (2011) 0.89
Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer. BMC Res Notes (2012) 0.88
Specificity of interaction between clostridium perfringens enterotoxin and claudin-family tight junction proteins. Toxins (Basel) (2010) 0.88
Tight junction protein claudin-1 is differentially expressed in craniopharyngioma subtypes and indicates invasive tumor growth. Neuro Oncol (2013) 0.87
Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9. Breast Cancer Res (2008) 0.87
The distinct expression patterns of claudin-10, -14, -17 and E-cadherin between adjacent non-neoplastic tissues and gastric cancer tissues. Diagn Pathol (2013) 0.86
Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs. J Gastroenterol (2010) 0.86
Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas. Am J Obstet Gynecol (2009) 0.86
Clinicopathological significance of claudin-4 in gastric carcinoma. World J Surg Oncol (2013) 0.86
Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis. Ann Transl Med (2015) 0.86
Recent advances in the field of anti-cancer immunotherapy. BBA Clin (2015) 0.85
Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma. J Cancer Res Clin Oncol (2008) 0.84
The distinct expression patterns of claudin-2, -6, and -11 between human gastric neoplasms and adjacent non-neoplastic tissues. Diagn Pathol (2013) 0.84
Claudin 1 expression in basal-like breast cancer is related to patient age. BMC Cancer (2013) 0.84
Translational application of epigenetic alterations: ovarian cancer as a model. FEBS Lett (2011) 0.83
Ephrin-A1 inhibits NSCLC tumor growth via induction of Cdx-2 a tumor suppressor gene. BMC Cancer (2012) 0.83
Claudin-6: a novel receptor for CPE-mediated cytotoxicity in ovarian cancer. Oncogenesis (2012) 0.83
Killing me softly--future challenges in apoptosis research. Int J Mol Sci (2014) 0.83
Claudin 1 in Breast Cancer: New Insights. J Clin Med (2015) 0.82
Tumor-specific marker genes for intrahepatic cholangiocarcinoma: utility and mechanistic insight. J Hepatol (2008) 0.82
Possible angiogenic roles for claudin-4 in ovarian cancer. Cancer Biol Ther (2009) 0.82
Quantitative molecular profiling of biomarkers for pancreatic cancer with functionalized quantum dots. Nanomedicine (2012) 0.81
Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation. Dev Dyn (2012) 0.81
Gastrointestinal response and endotoxemia during intense exercise in hot and cool environments. Eur J Appl Physiol (2013) 0.81
Overexpression of Claudin-1 is Associated with Advanced Clinical Stage and Invasive Pathologic Characteristics of Oral Squamous Cell Carcinoma. Head Neck Pathol (2014) 0.81
Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines. Histochem Cell Biol (2012) 0.81
Expression patterns of claudin family of tight-junction proteins in the mouse prostate. Histochem Cell Biol (2007) 0.81
The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues. Int J Clin Exp Pathol (2015) 0.81
Differential expression of claudin family proteins in mouse ovarian serous papillary epithelial adenoma in aging FSH receptor-deficient mutants. Neoplasia (2006) 0.81
Importance of collection in gene set enrichment analysis of drug response in cancer cell lines. Sci Rep (2014) 0.81
Novel pharmacologic targeting of tight junctions and focal adhesions in prostate cancer cells. PLoS One (2014) 0.81
Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer. Womens Health (Lond Engl) (2014) 0.80
Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue. Virology (2013) 0.80
Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth. PLoS One (2013) 0.80
Prognostic and clinical significance of claudin-4 in gastric cancer: a meta-analysis. World J Surg Oncol (2015) 0.80
Genes with relevance for early to late progression of colon carcinoma based on combined genomic and transcriptomic information from the same patients. Cancer Inform (2010) 0.80
Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front. PLoS One (2013) 0.80
Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells. Cancer Sci (2013) 0.80
Type AB thymoma is not a mixed tumor of type A and type B thymomas, but a distinct type of thymoma. Virchows Arch (2014) 0.79
Developmental lung expression and transcriptional regulation of claudin-6 by TTF-1, Gata-6, and FoxA2. Respir Res (2014) 0.79
High Expression of the Newly Found Long Noncoding RNA Z38 Promotes Cell Proliferation and Oncogenic Activity in Breast Cancer. J Cancer (2016) 0.79