Published in Proc Natl Acad Sci U S A on November 07, 2005
Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs). Nucl Recept Signal (2009) 1.80
Vitamin A and retinoid signaling: genomic and nongenomic effects. J Lipid Res (2013) 1.43
P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription. EMBO J (2006) 1.17
A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters. EMBO J (2008) 1.16
High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. J Cell Physiol (2012) 1.00
Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors. Cell Cycle (2015) 0.98
E-box-independent regulation of transcription and differentiation by MYC. Nat Cell Biol (2011) 0.95
Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7. Proc Natl Acad Sci U S A (2006) 0.93
Acinus-S' represses retinoic acid receptor (RAR)-regulated gene expression through interaction with the B domains of RARs. Mol Cell Biol (2008) 0.90
A G-tract element in apoptotic agents-induced alternative splicing. Nucleic Acids Res (2008) 0.88
Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice. PLoS One (2012) 0.84
Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ. PLoS One (2017) 0.75
A decade of molecular biology of retinoic acid receptors. FASEB J (1996) 9.70
Protein-protein interactions define specificity in signal transduction. Genes Dev (2000) 3.62
Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol Cell Biol (1996) 3.50
Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene (2004) 3.41
The nuclear receptor ligand-binding domain: structure and function. Curr Opin Cell Biol (1998) 3.08
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A. Nat Genet (2004) 2.54
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors. Cell (1992) 2.50
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J (1996) 2.47
PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol Cell (2005) 2.44
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. Mol Cell (2000) 2.33
Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7. Cell (1997) 1.91
Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7. Mol Cell (2000) 1.77
An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes Dev (2002) 1.73
Docking sites on substrate proteins direct extracellular signal-regulated kinase to phosphorylate specific residues. J Biol Chem (2001) 1.72
Structural studies on nuclear receptors. Cell Mol Life Sci (2000) 1.57
Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH. EMBO J (1997) 1.56
XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RARalpha. Cell (2002) 1.51
A bipartite substrate recognition motif for cyclin-dependent kinases. J Biol Chem (2000) 1.41
Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR. J Mol Biol (2001) 1.33
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner. Mol Cell Biol (1997) 1.31
Dynamic combinatorial networks in nuclear receptor-mediated transcription. J Biol Chem (2005) 1.27
Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex. Mol Cell Biol (1999) 1.22
Specificity determinants in MAPK signaling to transcription factors. J Biol Chem (2002) 1.20
Transcriptional activities of retinoic acid receptors. Vitam Horm (2005) 1.16
Signature of the oligomeric behaviour of nuclear receptors at the sequence and structural level. EMBO Rep (2004) 1.08
The structure of cyclin H: common mode of kinase activation and specific features. EMBO J (1997) 1.08
Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase. EMBO J (1999) 1.04
Vinexin beta interacts with the non-phosphorylated AF-1 domain of retinoid receptor gamma (RARgamma) and represses RARgamma-mediated transcription. J Biol Chem (2005) 1.03
The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors. J Biol Chem (1997) 1.02
TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7. J Biol Chem (2000) 1.00
Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities. J Biol Chem (2000) 0.94
Regulation of CAK kinase activity by p53. Oncogene (1998) 0.89
A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1. Biol Proced Online (2004) 0.81
Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene (2004) 3.41
Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nat Med (2008) 2.85
Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis. Endocrinology (2005) 1.76
Recombinant protein expression and solubility screening in Escherichia coli: a comparative study. Acta Crystallogr D Biol Crystallogr (2006) 1.65
XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RARalpha. Cell (2002) 1.51
Vitamin A and retinoid signaling: genomic and nongenomic effects. J Lipid Res (2013) 1.43
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies. Acta Crystallogr D Biol Crystallogr (2006) 1.39
High-resolution X-ray structure of an acyl-enzyme species for the class D OXA-10 beta-lactamase. J Am Chem Soc (2002) 1.36
The crystal structure of the phosphorylation domain in PhoP reveals a functional tandem association mediated by an asymmetric interface. J Bacteriol (2003) 1.27
Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation. EMBO J (2002) 1.18
Residue R113 is essential for PhoP dimerization and function: a residue buried in the asymmetric PhoP dimer interface determined in the PhoPN three-dimensional crystal structure. J Bacteriol (2003) 1.17
P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription. EMBO J (2006) 1.17
A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters. EMBO J (2008) 1.16
X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction. J Am Chem Soc (2004) 1.15
Protein kinases and the proteasome join in the combinatorial control of transcription by nuclear retinoic acid receptors. Trends Cell Biol (2007) 1.14
Involvement of a mate chaperone (TorD) in the maturation pathway of molybdoenzyme TorA. J Biol Chem (2003) 1.09
Molecular dynamics at the root of expansion of function in the M69L inhibitor-resistant TEM beta-lactamase from Escherichia coli. J Am Chem Soc (2002) 1.08
The molecular physiology of nuclear retinoic acid receptors. From health to disease. Biochim Biophys Acta (2010) 1.08
Nuclear retinoic acid receptors: conductors of the retinoic acid symphony during development. Mol Cell Endocrinol (2011) 1.08
Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus. Acta Crystallogr D Biol Crystallogr (2003) 1.05
Vinexin beta interacts with the non-phosphorylated AF-1 domain of retinoid receptor gamma (RARgamma) and represses RARgamma-mediated transcription. J Biol Chem (2005) 1.03
Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii. J Biol Chem (2004) 1.00
Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity. Cell Signal (2005) 0.98
Characterization and multiple molecular forms of TorD from Shewanella massilia, the putative chaperone of the molybdoenzyme TorA. Protein Sci (2002) 0.98
A novel protein fold and extreme domain swapping in the dimeric TorD chaperone from Shewanella massilia. Structure (2003) 0.97
Insights into metazoan evolution from Alvinella pompejana cDNAs. BMC Genomics (2010) 0.97
Robots, pipelines, polyproteins: enabling multiprotein expression in prokaryotic and eukaryotic cells. J Struct Biol (2011) 0.96
Cyclin D3 is a cofactor of retinoic acid receptors, modulating their activity in the presence of cellular retinoic acid-binding protein II. J Biol Chem (2002) 0.96
The AF-1 and AF-2 domains of RAR gamma 2 and RXR alpha cooperate for triggering the transactivation and the degradation of RAR gamma 2/RXR alpha heterodimers. J Biol Chem (2003) 0.95
Genome-wide in silico identification of new conserved and functional retinoic acid receptor response elements (direct repeats separated by 5 bp). J Biol Chem (2011) 0.94
Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions. Hum Mol Genet (2011) 0.94
Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7. Proc Natl Acad Sci U S A (2006) 0.93
The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. PLoS One (2011) 0.92
Crystallographic and biochemical studies of DivK reveal novel features of an essential response regulator in Caulobacter crescentus. J Biol Chem (2002) 0.91
Structure of OsmC from Escherichia coli: a salt-shock-induced protein. Acta Crystallogr D Biol Crystallogr (2004) 0.91
Crystal structure of a stress inducible protein from Mycoplasma pneumoniae at 2.85 A resolution. J Struct Funct Genomics (2003) 0.90
A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies. Anal Biochem (2008) 0.90
Molecular dynamics of the FixJ receiver domain: movement of the beta4-alpha4 loop correlates with the in and out flip of Phe101. Protein Sci (2002) 0.89
The phosphorylation site located in the A region of retinoic X receptor alpha is required for the antiproliferative effect of retinoic acid (RA) and the activation of RA target genes in F9 cells. J Biol Chem (2002) 0.89
A new lectin family with structure similarity to actinoporins revealed by the crystal structure of Xerocomus chrysenteron lectin XCL. J Mol Biol (2004) 0.88
Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo. Am J Physiol Endocrinol Metab (2002) 0.86
Phosphorylation of ICBP90 by protein kinase A enhances topoisomerase IIalpha expression. Biochem Biophys Res Commun (2004) 0.85
Evolution of nuclear retinoic acid receptor alpha (RARα) phosphorylation sites. Serine gain provides fine-tuned regulation. Mol Biol Evol (2011) 0.85
Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha. Oncogene (2005) 0.85
High level protein expression in mammalian cells using a safe viral vector: modified vaccinia virus Ankara. Protein Expr Purif (2007) 0.83
TIF2 mediates the synergy between RARalpha 1 activation functions AF-1 and AF-2. J Biol Chem (2002) 0.83
Nuclear and extra-nuclear effects of retinoid acid receptors: how they are interconnected. Subcell Biochem (2014) 0.83
Phosphorylation control of nuclear receptors. Methods Mol Biol (2010) 0.83
Energy resolution of the CdTe-XPAD detector: calibration and potential for Laue diffraction measurements on protein crystals. J Synchrotron Radiat (2012) 0.82
SUG-1 plays proteolytic and non-proteolytic roles in the control of retinoic acid target genes via its interaction with SRC-3. J Biol Chem (2009) 0.82
Phosphorylation of the retinoic acid receptor RARγ2 is crucial for the neuronal differentiation of mouse embryonic stem cells. J Cell Sci (2014) 0.80
Phosphorylation of the retinoic acid receptor alpha induces a mechanical allosteric regulation and changes in internal dynamics. PLoS Comput Biol (2013) 0.78
Vinexinß, an atypical "sensor" of retinoic acid receptor gamma signaling: union and sequestration, separation, and phosphorylation. FASEB J (2010) 0.78
Single-chain Fv fragment antibodies selected from an intrabody library as effective mono- or bivalent reagents for in vitro protein detection. J Immunol Methods (2011) 0.78
Characterization and crystallization of DivK, an essential response regulator for cell division and differentiation in Caulobacter crescentus. Acta Crystallogr D Biol Crystallogr (2002) 0.77
Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts. J Cell Sci (2013) 0.77
Retinoic-acid receptor beta expression in melanocytes. Eur J Dermatol (2004) 0.77
History of retinoic acid receptors. Subcell Biochem (2014) 0.76
Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Mol Endocrinol (2014) 0.76
The antiapoptotic protein ICBP90 is a target for protein kinase 2. Ann N Y Acad Sci (2004) 0.76
Retinoid acid receptor expression is helpful to distinguish between adenoma and well-differentiated carcinoma in the thyroid. Virchows Arch (2013) 0.75