Published in Annu Rev Genet on January 01, 2005
Small RNAs as guardians of the genome. Cell (2009) 8.88
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature (2008) 6.81
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44
A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii. Genes Dev (2007) 4.95
Aneuploidy: cells losing their balance. Genetics (2008) 3.48
The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell (2009) 3.14
On the origin and functions of RNA-mediated silencing: from protists to man. Curr Genet (2006) 3.05
The biogenesis and regulation of telomerase holoenzymes. Nat Rev Mol Cell Biol (2006) 2.94
Condensins: universal organizers of chromosomes with diverse functions. Genes Dev (2012) 2.40
Microarray analyses of gene expression during the Tetrahymena thermophila life cycle. PLoS One (2009) 2.11
Two classes of endogenous small RNAs in Tetrahymena thermophila. Genes Dev (2005) 2.08
2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena. RNA (2009) 1.76
Palindromic gene amplification--an evolutionarily conserved role for DNA inverted repeats in the genome. Nat Rev Cancer (2009) 1.62
Maternal noncoding transcripts antagonize the targeting of DNA elimination by scanRNAs in Paramecium tetraurelia. Genes Dev (2008) 1.60
Programmed loss of millions of base pairs from a vertebrate genome. Proc Natl Acad Sci U S A (2009) 1.58
Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles. Genome Res (2011) 1.57
A domesticated piggyBac transposase plays key roles in heterochromatin dynamics and DNA cleavage during programmed DNA deletion in Tetrahymena thermophila. Mol Biol Cell (2010) 1.42
Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure. BMC Genomics (2008) 1.40
The Paramecium germline genome provides a niche for intragenic parasitic DNA: evolutionary dynamics of internal eliminated sequences. PLoS Genet (2012) 1.38
Silencing-associated and meiosis-specific small RNA pathways in Paramecium tetraurelia. Nucleic Acids Res (2008) 1.34
An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. PLoS Genet (2008) 1.29
A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii. PLoS Pathog (2010) 1.27
Dynamic nuclear reorganization during genome remodeling of Tetrahymena. Biochim Biophys Acta (2008) 1.25
Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila. G3 (Bethesda) (2011) 1.16
Induction of gene silencing by hairpin RNA expression in Tetrahymena thermophila reveals a second small RNA pathway. Mol Cell Biol (2006) 1.15
Mating of the stichotrichous ciliate Oxytricha trifallax induces production of a class of 27 nt small RNAs derived from the parental macronucleus. PLoS One (2012) 1.03
Lia1p, a novel protein required during nuclear differentiation for genome-wide DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2007) 0.99
Positive and negative regulation of Tetrahymena telomerase holoenzyme. Mol Cell Biol (2007) 0.99
An essential role for the DNA breakage-repair protein Ku80 in programmed DNA rearrangements in Tetrahymena thermophila. Mol Biol Cell (2012) 0.97
Tudor nuclease genes and programmed DNA rearrangements in Tetrahymena thermophila. Eukaryot Cell (2007) 0.97
Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in Tetrahymena thermophila. Mol Cell Biol (2007) 0.95
The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena. Eukaryot Cell (2010) 0.94
The germ line limited M element of Tetrahymena is targeted for elimination from the somatic genome by a homology-dependent mechanism. Nucleic Acids Res (2006) 0.93
Posttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes. J Immunol (2010) 0.93
The evolutionary origin of a complex scrambled gene. Proc Natl Acad Sci U S A (2005) 0.92
Gene regulation in Giardia lambia involves a putative microRNA derived from a small nucleolar RNA. PLoS Negl Trop Dis (2011) 0.91
Tetrahymena functional genomics database (TetraFGD): an integrated resource for Tetrahymena functional genomics. Database (Oxford) (2013) 0.89
Tetrahymena thermophila JMJD3 homolog regulates H3K27 methylation and nuclear differentiation. Eukaryot Cell (2012) 0.89
Gene network landscape of the ciliate Tetrahymena thermophila. PLoS One (2011) 0.88
Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila. Eukaryot Cell (2012) 0.84
Structure of the germline genome of Tetrahymenathermophila and relationship to the massively rearranged somatic genome. Elife (2016) 0.84
Unusual augmentation of germline genome size in Cyclops kolensis (Crustacea, Copepoda): further evidence in support of a revised model of chromatin diminution. Chromosome Res (2011) 0.84
The condensin complex is essential for amitotic segregation of bulk chromosomes, but not nucleoli, in the ciliate Tetrahymena thermophila. Mol Cell Biol (2006) 0.81
A recombinase system facilitates cloning of expression cassettes in the ciliate Tetrahymena thermophila. BMC Microbiol (2007) 0.81
The bifunctional dihydrofolate reductase thymidylate synthase of Tetrahymena thermophila provides a tool for molecular and biotechnology applications. BMC Biotechnol (2006) 0.81
Loading and pre-loading processes generate a distinct siRNA population in Tetrahymena. Biochem Biophys Res Commun (2013) 0.80
The role of piRNA and its potential clinical implications in cancer. Epigenomics (2015) 0.79
Subtraction by addition: domesticated transposases in programmed DNA elimination. Genes Dev (2009) 0.78
Do human transposable element small RNAs serve primarily as genome defenders or genome regulators? Mob Genet Elements (2012) 0.78
Expression, secretion and surface display of a human alkaline phosphatase by the ciliate Tetrahymena thermophila. BMC Biotechnol (2011) 0.78
Whole chromosome elimination and chromosome terminus elimination both contribute to somatic differentiation in Taiwanese hagfish Paramyxine sheni. Chromosome Res (2010) 0.78
The piRNA Pathway Guards the Germline Genome Against Transposable Elements. Adv Exp Med Biol (2016) 0.77
Programmed Minichromosome Elimination as a Mechanism for Somatic Genome Reduction in Tetrahymena thermophila. PLoS Genet (2016) 0.76
Intercepting noncoding messages between germline and soma. Genes Dev (2012) 0.75
Modulating somatic DNA copy number through maternal RNA. Proc Natl Acad Sci U S A (2010) 0.75
Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development. Development (2003) 1.16
An essential role for the DNA breakage-repair protein Ku80 in programmed DNA rearrangements in Tetrahymena thermophila. Mol Biol Cell (2012) 0.97
Programmed Genome Rearrangements in Tetrahymena. Microbiol Spectr (2014) 0.79
New phenotypes generated by the G57R mutation of BUD23 in Saccharomyces cerevisiae. Yeast (2012) 0.75