Published in Nucleic Acids Res on December 22, 2008
Small RNAs as guardians of the genome. Cell (2009) 8.88
Piwi-interacting RNAs protect DNA against loss during Oxytricha genome rearrangement. Cell (2012) 1.95
Genome-defence small RNAs exapted for epigenetic mating-type inheritance. Nature (2014) 1.72
PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements in the ciliate Paramecium tetraurelia. Genes Dev (2009) 1.53
Pdsg1 and Pdsg2, novel proteins involved in developmental genome remodelling in Paramecium. PLoS One (2014) 1.40
The Paramecium germline genome provides a niche for intragenic parasitic DNA: evolutionary dynamics of internal eliminated sequences. PLoS Genet (2012) 1.38
Epigenetics of ciliates. Cold Spring Harb Perspect Biol (2013) 1.14
Functional specialization of Piwi proteins in Paramecium tetraurelia from post-transcriptional gene silencing to genome remodelling. Nucleic Acids Res (2011) 1.13
Gene expression in a paleopolyploid: a transcriptome resource for the ciliate Paramecium tetraurelia. BMC Genomics (2010) 1.12
RNA-Mediated Epigenetic Programming of Genome Rearrangements. Annu Rev Genomics Hum Genet (2011) 1.06
The conjugation-specific Die5 protein is required for development of the somatic nucleus in both Paramecium and Tetrahymena. Eukaryot Cell (2010) 0.94
Epigenetic inheritance in ciliates. Curr Opin Microbiol (2009) 0.94
Distinct RNA-dependent RNA polymerases are required for RNAi triggered by double-stranded RNA versus truncated transgenes in Paramecium tetraurelia. Nucleic Acids Res (2010) 0.94
RNA-directed epigenetic regulation of DNA rearrangements. Essays Biochem (2010) 0.93
Genomes on the edge: programmed genome instability in ciliates. Cell (2013) 0.93
DNA rearrangements directed by non-coding RNAs in ciliates. Wiley Interdiscip Rev RNA (2011) 0.88
Programmed Genome Rearrangements in the Ciliate Oxytricha. Microbiol Spectr (2014) 0.84
New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing. Wiley Interdiscip Rev RNA (2013) 0.84
Genome-wide analysis of genetic and epigenetic control of programmed DNA deletion. Nucleic Acids Res (2014) 0.83
Local effect of enhancer of zeste-like reveals cooperation of epigenetic and cis-acting determinants for zygotic genome rearrangements. PLoS Genet (2014) 0.83
Functional study of genes essential for autogamy and nuclear reorganization in Paramecium. Eukaryot Cell (2011) 0.81
Primary and secondary siRNA synthesis triggered by RNAs from food bacteria in the ciliate Paramecium tetraurelia. Nucleic Acids Res (2015) 0.80
Loading and pre-loading processes generate a distinct siRNA population in Tetrahymena. Biochem Biophys Res Commun (2013) 0.80
A forward genetic screen reveals essential and non-essential RNAi factors in Paramecium tetraurelia. Nucleic Acids Res (2014) 0.79
DNA deletion as a mechanism for developmentally programmed centromere loss. Nucleic Acids Res (2015) 0.78
Subtraction by addition: domesticated transposases in programmed DNA elimination. Genes Dev (2009) 0.78
Transposons that clean up after themselves. Genome Biol (2009) 0.78
Ku-mediated coupling of DNA cleavage and repair during programmed genome rearrangements in the ciliate Paramecium tetraurelia. PLoS Genet (2014) 0.78
Evolutionary dynamics of a conserved sequence motif in the ribosomal genes of the ciliate Paramecium. BMC Evol Biol (2010) 0.77
TFIIS-Dependent Non-coding Transcription Regulates Developmental Genome Rearrangements. PLoS Genet (2015) 0.77
Diverse Evolutionary Trajectories for Small RNA Biogenesis Genes in the Oomycete Genus Phytophthora. Front Plant Sci (2016) 0.76
Cis-acting signals modulate the efficiency of programmed DNA elimination in Paramecium tetraurelia. Nucleic Acids Res (2015) 0.75
A meiosis-specific Spt5 homolog involved in non-coding transcription. Nucleic Acids Res (2017) 0.75
Preferential expression of scores of functionally and evolutionarily diverse DNA and RNA-binding proteins during Oxytricha trifallax macronuclear development. PLoS One (2017) 0.75
Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes. Nucleic Acids Res (2016) 0.75
Paramecium tetraurelia chromatin assembly factor-1-like protein PtCAF-1 is involved in RNA-mediated control of DNA elimination. Nucleic Acids Res (2014) 0.75
Two Sets of Piwi Proteins Are Involved in Distinct sRNA Pathways Leading to Elimination of Germline-Specific DNA. Cell Rep (2017) 0.75
Asymmetry in the assembly of the RNAi enzyme complex. Cell (2003) 22.18
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide. Cell (2008) 9.02
Developmentally regulated piRNA clusters implicate MILI in transposon control. Science (2007) 7.68
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science (2006) 7.15
RNAi-mediated pathways in the nucleus. Nat Rev Genet (2005) 6.55
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol (2005) 5.99
Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena. Cell (2002) 5.78
Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation. Cell (2008) 5.73
Secondary siRNAs result from unprimed RNA synthesis and form a distinct class. Science (2006) 5.49
RNA-quality control by the exosome. Nat Rev Mol Cell Biol (2006) 5.26
Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature (2006) 5.06
PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Mol Cell (2008) 4.48
Biogenesis and germline functions of piRNAs. Development (2007) 4.37
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell (2004) 4.34
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol Cell (2008) 3.37
Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena. Cell (2002) 3.16
The mechanism selecting the guide strand from small RNA duplexes is different among argonaute proteins. Plant Cell Physiol (2008) 3.15
Mighty Piwis defend the germline against genome intruders. Cell (2007) 3.06
On the origin and functions of RNA-mediated silencing: from protists to man. Curr Genet (2006) 3.05
A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase. Genes Dev (2004) 2.75
In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans. EMBO J (2007) 2.57
Small RNAs in genome rearrangement in Tetrahymena. Curr Opin Genet Dev (2004) 2.56
Cellular RNA-dependent RNA polymerase involved in posttranscriptional gene silencing has two distinct activity modes. Mol Cell (2002) 2.47
RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev (2007) 2.26
Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline. Nucleic Acids Res (2007) 2.22
Conjugation-specific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement. Genes Dev (2004) 2.19
Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena. Proc Natl Acad Sci U S A (2004) 2.10
Nowa1p and Nowa2p: novel putative RNA binding proteins involved in trans-nuclear crosstalk in Paramecium tetraurelia. Curr Biol (2005) 2.09
Two classes of endogenous small RNAs in Tetrahymena thermophila. Genes Dev (2005) 2.08
Germ line transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila. Mol Cell Biol (2005) 2.06
RNA-guided DNA deletion in Tetrahymena: an RNAi-based mechanism for programmed genome rearrangements. Annu Rev Genet (2005) 2.04
Homology-dependent gene silencing in Paramecium. Mol Biol Cell (1998) 1.98
piRNAs--the ancient hunters of genome invaders. Genes Dev (2007) 1.84
RNA interference by feeding in Paramecium. Trends Genet (2002) 1.83
Study of an RNA helicase implicates small RNA-noncoding RNA interactions in programmed DNA elimination in Tetrahymena. Genes Dev (2008) 1.82
Physical and functional coupling of RNA-dependent RNA polymerase and Dicer in the biogenesis of endogenous siRNAs. Nat Struct Mol Biol (2007) 1.80
Genome remodeling in ciliated protozoa. Annu Rev Microbiol (2002) 1.71
Developmental genome reorganization in ciliated protozoa: the transposon link. Prog Nucleic Acid Res Mol Biol (1997) 1.69
Small RNA guides for de novo DNA methylation in mammalian germ cells. Genes Dev (2008) 1.68
Homology-dependent maternal inhibition of developmental excision of internal eliminated sequences in Paramecium tetraurelia. Mol Cell Biol (1998) 1.67
Maternal noncoding transcripts antagonize the targeting of DNA elimination by scanRNAs in Paramecium tetraurelia. Genes Dev (2008) 1.60
RNA-mediated programming of developmental genome rearrangements in Paramecium tetraurelia. Mol Cell Biol (2004) 1.57
Global role for polyadenylation-assisted nuclear RNA degradation in posttranscriptional gene silencing. Mol Cell Biol (2007) 1.43
Large-scale genome remodelling by the developmentally programmed elimination of germ line sequences in the ciliate Paramecium. Res Microbiol (2004) 1.28
Communication between parental and developing genomes during tetrahymena nuclear differentiation is likely mediated by homologous RNAs. Genetics (2004) 1.21
Induction of gene silencing by hairpin RNA expression in Tetrahymena thermophila reveals a second small RNA pathway. Mol Cell Biol (2006) 1.15
Transgene-mediated post-transcriptional gene silencing is inhibited by 3' non-coding sequences in Paramecium. Nucleic Acids Res (2001) 1.10
snRNA and heterochromatin formation are involved in DNA excision during macronuclear development in stichotrichous ciliates. Eukaryot Cell (2005) 0.97
Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature (2006) 5.06
Translational control of intron splicing in eukaryotes. Nature (2008) 2.15
Nowa1p and Nowa2p: novel putative RNA binding proteins involved in trans-nuclear crosstalk in Paramecium tetraurelia. Curr Biol (2005) 2.09
The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. PLoS Biol (2013) 2.08
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. Oncogene (2002) 1.97
piRNA-mediated transgenerational inheritance of an acquired trait. Genome Res (2012) 1.95
Piwi-interacting RNAs protect DNA against loss during Oxytricha genome rearrangement. Cell (2012) 1.95
Maternal noncoding transcripts antagonize the targeting of DNA elimination by scanRNAs in Paramecium tetraurelia. Genes Dev (2008) 1.60
RNA-mediated programming of developmental genome rearrangements in Paramecium tetraurelia. Mol Cell Biol (2004) 1.57
PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements in the ciliate Paramecium tetraurelia. Genes Dev (2009) 1.53
The Paramecium germline genome provides a niche for intragenic parasitic DNA: evolutionary dynamics of internal eliminated sequences. PLoS Genet (2012) 1.38
Developmentally regulated chromosome fragmentation linked to imprecise elimination of repeated sequences in paramecia. Eukaryot Cell (2003) 1.30
Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies. Schizophr Bull (2006) 1.26
Duplicated dockerin subdomains of Clostridium thermocellum endoglucanase CelD bind to a cohesin domain of the scaffolding protein CipA with distinct thermodynamic parameters and a negative cooperativity. Biochemistry (2002) 1.20
Developmental genome rearrangements in ciliates: a natural genomic subtraction mediated by non-coding transcripts. Trends Genet (2009) 1.20
Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline. Genome Res (2008) 1.16
Epigenetics of ciliates. Cold Spring Harb Perspect Biol (2013) 1.14
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain. Neuroimage (2007) 1.14
Functional specialization of Piwi proteins in Paramecium tetraurelia from post-transcriptional gene silencing to genome remodelling. Nucleic Acids Res (2011) 1.13
Gene expression in a paleopolyploid: a transcriptome resource for the ciliate Paramecium tetraurelia. BMC Genomics (2010) 1.12
The repatterning of eukaryotic genomes by random genetic drift. Annu Rev Genomics Hum Genet (2011) 1.09
RNA-guided DNA rearrangements in ciliates: is the best genome defence a good offence? Biol Cell (2012) 1.01
Simultaneous 3D visualization and quantification of murine bone and bone vasculature using micro-computed tomography and vascular replica. Microsc Res Tech (2009) 1.00
High coding density on the largest Paramecium tetraurelia somatic chromosome. Curr Biol (2004) 1.00
Developmentally programmed DNA splicing in Paramecium reveals short-distance crosstalk between DNA cleavage sites. Nucleic Acids Res (2008) 0.99
The Oxytricha trifallax mitochondrial genome. Genome Biol Evol (2011) 0.98
Highly precise and developmentally programmed genome assembly in Paramecium requires ligase IV-dependent end joining. PLoS Genet (2011) 0.96
Distinct RNA-dependent RNA polymerases are required for RNAi triggered by double-stranded RNA versus truncated transgenes in Paramecium tetraurelia. Nucleic Acids Res (2010) 0.94
Silencing specific Paramecium tetraurelia genes by feeding double-stranded RNA. Cold Spring Harb Protoc (2010) 0.87
Paramecium tetraurelia: the renaissance of an early unicellular model. Cold Spring Harb Protoc (2010) 0.86
Cleft lip repair: technical refinements for the wide cleft. Craniomaxillofac Trauma Reconstr (2010) 0.84
Relationship between genome and epigenome--challenges and requirements for future research. BMC Genomics (2014) 0.82
Functional study of genes essential for autogamy and nuclear reorganization in Paramecium. Eukaryot Cell (2011) 0.81
Mass culture of Paramecium tetraurelia. Cold Spring Harb Protoc (2010) 0.81
RNA-dependent genome processing during nuclear differentiation: the model systems of stichotrichous ciliates. Epigenomics (2013) 0.81
Immunocytochemistry of Paramecium cytoskeletal structures. Cold Spring Harb Protoc (2010) 0.81
Programmed Rearrangement in Ciliates: Paramecium. Microbiol Spectr (2014) 0.80
Maintaining clonal Paramecium tetraurelia cell lines of controlled age through daily reisolation. Cold Spring Harb Protoc (2010) 0.80
Syndesmosis fixation: analysis of shear stress via axial load on 3.5-mm and 4.5-mm quadricortical syndesmotic screws. J Foot Ankle Surg (2006) 0.79
DNA microinjection into the macronucleus of paramecium. Cold Spring Harb Protoc (2010) 0.78
The eukaryotic way to defend and edit genomes by sRNA-targeted DNA deletion. Ann N Y Acad Sci (2015) 0.78
Isolation and expression of two genes encoding eukaryotic release factor 1 from Paramecium tetraurelia. J Eukaryot Microbiol (2002) 0.77
Are extended show, venue change solutions to crowded Spring Session? J Calif Dent Assoc (2008) 0.75
The impact of stage hypnosis on audience members and participants. Int J Clin Exp Hypn (2004) 0.75
Developing military cultural competency in health care providers. Acad Med (2012) 0.75