E A Golemis

Author PubWeight™ 64.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Correlation of two-hybrid affinity data with in vitro measurements. Mol Cell Biol 1995 4.63
2 The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. J Biol Chem 1997 2.42
3 Integrin signalling: a new Cas(t) of characters enters the stage. Trends Cell Biol 2000 2.39
4 Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22. Oncogene 1997 2.31
5 Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2. Oncogene 1999 2.20
6 Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol Cell Biol 1996 2.12
7 AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation. Mol Cell Biol 1995 2.03
8 MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1. Proc Natl Acad Sci U S A 1999 1.99
9 HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene 2006 1.94
10 The continued evolution of two-hybrid screening approaches in yeast: how to outwit different preys with different baits. Gene 2000 1.86
11 Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments. Mol Cell Biol 1998 1.56
12 ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks. J Biol Chem 1997 1.44
13 Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II. Oncogene 1998 1.41
14 Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Mol Biol Cell 1995 1.32
15 The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Mol Cell Biol 2000 1.31
16 Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II. Mol Cell Biol 1998 1.30
17 Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol Cell Biol 2001 1.30
18 Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway. Eur J Immunol 2001 1.25
19 Uses of lacZ to study gene function: evaluation of beta-galactosidase assays employed in the yeast two-hybrid system. Anal Biochem 2000 1.23
20 Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells. J Biol Chem 1997 1.23
21 A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. EMBO J 2000 1.11
22 The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1. J Biol Chem 1997 1.11
23 HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression. Oncogene 2011 1.10
24 Using the yeast interaction trap and other two-hybrid-based approaches to study protein-protein interactions. Methods 2001 1.09
25 Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1. Gene 2000 1.09
26 Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1). J Biol Chem 1997 1.07
27 A two-hybrid dual bait system to discriminate specificity of protein interactions. J Biol Chem 1999 1.04
28 Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain. Exp Cell Res 1999 1.00
29 Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene 2011 0.98
30 Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells. Leuk Lymphoma 1997 0.96
31 The evolutionarily conserved Dim1 protein defines a novel branch of the thioredoxin fold superfamily. Physiol Genomics 1999 0.94
32 HEI10 negatively regulates cell invasion by inhibiting cyclin B/Cdk1 and other promotility proteins. Oncogene 2007 0.92
33 Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42. J Biol Chem 2001 0.92
34 The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1. J Biol Chem 1999 0.91
35 A functional association between merlin and HEI10, a cell cycle regulator. Oncogene 2006 0.90
36 Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer. Br J Cancer 2012 0.89
37 Approaches to detecting false positives in yeast two-hybrid systems. Biotechniques 2000 0.88
38 The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics. Neuroscience 2009 0.88
39 Two-hybrid system and false positives. Approaches to detection and elimination. Methods Mol Biol 2001 0.87
40 Streamlined yeast colorimetric reporter activity assays using scanners and plate readers. Biotechniques 2000 0.86
41 Genomic analysis utilizing the yeast two-hybrid system. Methods Mol Biol 2001 0.86
42 Ligand-free RAR can interact with the RNA polymerase II subunit hsRPB7 and repress transcription. Endocrine 1999 0.86
43 Identification of ArgBP1, an Arg protein tyrosine kinase binding protein that is the human homologue of a CNS-specific Xenopus gene. Oncogene 1996 0.85
44 LexA-based two-hybrid systems. Methods Enzymol 2000 0.85
45 Redefinition of the yeast two-hybrid system in dialogue with changing priorities in biological research. Biotechniques 2001 0.84
46 Conversion of mRNA into double-stranded cDNA. Curr Protoc Mol Biol 2001 0.81
47 DUSP6 regulates drug sensitivity by modulating DNA damage response. Br J Cancer 2013 0.80
48 Two-hybrid dual bait system to discriminate specificity of protein interactions in small GTPases. Methods Enzymol 2001 0.79
49 Interactions between the full complement of human RNA polymerase II subunits. FEBS Lett 1999 0.78
50 Targeting proteins to specific cellular compartments to optimize physiological activity. Methods Enzymol 2001 0.77
51 Encroaching genomics: adapting large-scale science to small academic laboratories. Physiol Genomics 2000 0.75
52 Vectors to target protein domains to different cellular compartments. Biotechniques 1998 0.75