PubRank

Martin J Walsh

Author PubWeight™ 47.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 2010 6.94
2 Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol 2012 3.40
3 Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev 2009 2.98
4 The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood 2007 2.58
5 High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells. Proc Natl Acad Sci U S A 2014 2.50
6 CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription. Proc Natl Acad Sci U S A 2004 2.38
7 Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature 2010 2.02
8 Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. J Biol Chem 2005 1.46
9 Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation. Proc Natl Acad Sci U S A 2012 1.33
10 Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expression. Cancer Res 2011 1.31
11 G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta. J Biol Chem 2008 1.28
12 Structure and hemimethylated CpG binding of the SRA domain from human UHRF1. J Biol Chem 2008 1.26
13 Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation. Cancer Res 2005 1.20
14 p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase. PLoS One 2010 1.18
15 Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1. J Biol Chem 2004 1.16
16 The ZNF217 oncogene is a candidate organizer of repressive histone modifiers. Epigenetics 2009 1.14
17 Structure and chromosomal DNA binding of the SWIRM domain. Nat Struct Mol Biol 2005 1.06
18 Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription. Proc Natl Acad Sci U S A 2008 1.05
19 The epigenetic signature of CFTR expression is co-ordinated via chromatin acetylation through a complex intronic element. Biochem J 2007 0.97
20 Carbamazepine is an inhibitor of histone deacetylases. Life Sci 2005 0.96
21 A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells. J Biol Chem 2009 0.93
22 KLF6 degradation after apoptotic DNA damage. FEBS Lett 2006 0.93
23 Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation. EMBO J 2013 0.89
24 Studies for the synthesis of xenicane diterpenes. A stereocontrolled total synthesis of 4-hydroxydictyolactone. J Am Chem Soc 2009 0.89
25 Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein. J Med Chem 2011 0.89
26 Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna (nilotinib): evidence for transport of Tasigna and its fluorescent derivative by ABC drug transporters. Mol Pharm 2011 0.88
27 Immunomodulatory effect of the antiasthma Chinese herbal formula MSSM-002 on TH2 cells. J Allergy Clin Immunol 2004 0.87
28 Studies for the synthesis of marine natural products. Pure Appl Chem 2009 0.84
29 A network medicine approach to build a comprehensive atlas for the prognosis of human cancer. Brief Bioinform 2016 0.82
30 Fgfr3 is a transcriptional target of Ap2delta and Ash2l-containing histone methyltransferase complexes. PLoS One 2009 0.81
31 Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors. Bioorg Med Chem Lett 2012 0.79
32 A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase. Biochem J 2012 0.77