Published in J Biol Chem on October 22, 2008
Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet (2010) 15.70
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Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. Anal Chem (2011) 0.79
Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway. Cell Mol Life Sci (2016) 0.79
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Uhrf2 is important for DNA damage response in vascular smooth muscle cells. Biochem Biophys Res Commun (2013) 0.78
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Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain. Sci Rep (2016) 0.75
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Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase. EMBO J (2006) 2.89
ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation. Mol Cell Biol (2007) 2.69
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Np95 is a histone-binding protein endowed with ubiquitin ligase activity. Mol Cell Biol (2004) 2.35
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The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression. Oncogene (2007) 1.97
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth. Mol Biol Cell (2005) 1.68
Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma. Gastroenterology (2005) 1.61
The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future? Pharmacol Ther (2007) 1.59
The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin. Mol Biol Cell (2008) 1.53
ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells. Br J Cancer (2003) 1.53
Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions? Hum Pathol (2005) 1.11
Overexpression of ICBP90, a novel CCAAT-binding protein, overcomes cell contact inhibition by forcing topoisomerase II alpha expression. Anticancer Res (2003) 1.00
Identification of novel differentially expressed genes in human astrocytomas by cDNA representational difference analysis. Brain Res Mol Brain Res (2005) 0.99
Full transcriptome analysis of rhabdomyosarcoma, normal, and fetal skeletal muscle: statistical comparison of multiple SAGE libraries. FASEB J (2005) 0.95
Plant SET- and RING-associated domain proteins in heterochromatinization. Plant J (2007) 0.89
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell (2010) 6.94
Structure and conserved RNA binding of the PAZ domain. Nature (2003) 5.28
Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol (2006) 4.55
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol Cell Biol (2008) 3.74
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell (2007) 3.51
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol (2012) 3.40
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev (2009) 2.98
Migrastatin analogues target fascin to block tumour metastasis. Nature (2010) 2.84
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. Mol Cell (2007) 2.77
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood (2007) 2.58
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells. Proc Natl Acad Sci U S A (2014) 2.50
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol Cell (2004) 2.43
Structure and regulation of MAPK phosphatases. Cell Signal (2004) 2.42
CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription. Proc Natl Acad Sci U S A (2004) 2.38
Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain. Mol Cell (2002) 2.20
Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature (2010) 2.02
The role of human bromodomains in chromatin biology and gene transcription. Curr Opin Drug Discov Devel (2009) 1.99
Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nat Immunol (2006) 1.92
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proc Natl Acad Sci U S A (2012) 1.89
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (2012) 1.88
Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. Structure (2008) 1.86
The PHD finger: a versatile epigenome reader. Trends Biochem Sci (2011) 1.81
A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3. Nat Struct Biol (2003) 1.67
Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. J Biol Chem (2012) 1.66
Solution structure of the MAPK phosphatase PAC-1 catalytic domain. Insights into substrate-induced enzymatic activation of MKP. Structure (2003) 1.54
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J (2002) 1.49
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. J Biol Chem (2005) 1.46
BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy. Cancer Res (2013) 1.43
Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. J Biol Chem (2011) 1.43
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem Biol (2011) 1.35
Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator. Structure (2009) 1.35
Epigenetic transcriptional repression of cellular genes by a viral SET protein. Nat Cell Biol (2008) 1.34
Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation. Proc Natl Acad Sci U S A (2012) 1.33
Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing. Nat Struct Mol Biol (2008) 1.32
Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expression. Cancer Res (2011) 1.31
Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase. J Mol Biol (2006) 1.30
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G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta. J Biol Chem (2008) 1.28
Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol (2006) 1.25
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation. Cancer Res (2005) 1.20
Selective small molecules blocking HIV-1 Tat and coactivator PCAF association. J Am Chem Soc (2005) 1.18
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase. PLoS One (2010) 1.18
Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1. J Biol Chem (2004) 1.16
The ZNF217 oncogene is a candidate organizer of repressive histone modifiers. Epigenetics (2009) 1.14
UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail. J Mol Biol (2011) 1.13
Structure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription. Biochemistry (2011) 1.10
Structure and chromosomal DNA binding of the SWIRM domain. Nat Struct Mol Biol (2005) 1.06
Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription. Proc Natl Acad Sci U S A (2008) 1.05
T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. J Exp Med (2013) 1.03
Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2. Cell Res (2010) 1.02
Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation. Novartis Found Symp (2004) 1.01
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A 14-amino acid sequence with a beta-turn structure is required for apical membrane sorting of the rat ileal bile acid transporter. J Biol Chem (2002) 1.01
Molecular mechanism of fascin function in filopodial formation. J Biol Chem (2012) 0.99
A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition. Immunity (2008) 0.98
The epigenetic signature of CFTR expression is co-ordinated via chromatin acetylation through a complex intronic element. Biochem J (2007) 0.97
Characterization of a naphthalene dioxygenase endowed with an exceptionally broad substrate specificity toward polycyclic aromatic hydrocarbons. Biochemistry (2006) 0.97
Carbamazepine is an inhibitor of histone deacetylases. Life Sci (2005) 0.96
Grape berry plasma membrane proteome analysis and its differential expression during ripening. J Exp Bot (2008) 0.95
The SUVR4 histone lysine methyltransferase binds ubiquitin and converts H3K9me1 to H3K9me3 on transposon chromatin in Arabidopsis. PLoS Genet (2011) 0.95
Structure of a [2Fe-2S] ferredoxin from Rhodobacter capsulatus likely involved in Fe-S cluster biogenesis and conformational changes observed upon reduction. J Biol Inorg Chem (2006) 0.94
Biochemical profiling of histone binding selectivity of the yeast bromodomain family. PLoS One (2010) 0.93
Viral-encoded enzymes that target host chromatin functions. Biochim Biophys Acta (2009) 0.93
Computer aided identification of small molecules disrupting uPAR/alpha5beta1--integrin interaction: a new paradigm for metastasis prevention. PLoS One (2009) 0.93
Visualization of microvasculature by x-ray in-line phase contrast imaging in rat spinal cord. Phys Med Biol (2012) 0.93
A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells. J Biol Chem (2009) 0.93
KLF6 degradation after apoptotic DNA damage. FEBS Lett (2006) 0.93
Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J Med Chem (2013) 0.93
Structure-guided optimization of small molecules inhibiting human immunodeficiency virus 1 Tat association with the human coactivator p300/CREB binding protein-associated factor. J Med Chem (2007) 0.92