Published in Am J Epidemiol on November 30, 2005
Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study | NCT00646152
Influenza in tropical regions. PLoS Med (2006) 6.82
The guinea pig as a transmission model for human influenza viruses. Proc Natl Acad Sci U S A (2006) 4.58
Social network sensors for early detection of contagious outbreaks. PLoS One (2010) 3.68
Evidence links increases in public health spending to declines in preventable deaths. Health Aff (Millwood) (2011) 3.11
Improving the estimation of influenza-related mortality over a seasonal baseline. Epidemiology (2012) 2.68
The effect of universal influenza immunization on mortality and health care use. PLoS Med (2008) 2.01
Animal models for the study of influenza pathogenesis and therapy. Antiviral Res (2009) 1.90
Trends in recorded influenza mortality: United States, 1900-2004. Am J Public Health (2008) 1.88
Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge. Proc Natl Acad Sci U S A (2009) 1.82
Estimating influenza-associated deaths in the United States. Am J Public Health (2009) 1.73
Modifiers of diurnal temperature range and mortality association in six Korean cities. Int J Biometeorol (2011) 1.73
TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells. J Virol (2010) 1.66
Comparing pandemic to seasonal influenza mortality: moderate impact overall but high mortality in young children. PLoS One (2012) 1.64
Elevated influenza-related excess mortality in South African elderly individuals, 1998-2005. Clin Infect Dis (2010) 1.62
Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. J Infect Dis (2012) 1.54
Augmented lung inflammation protects against influenza A pneumonia. PLoS One (2009) 1.47
Protection of racial/ethnic minority populations during an influenza pandemic. Am J Public Health (2009) 1.40
Influenza. Crit Care Med (2008) 1.39
Trends for influenza-related deaths during pandemic and epidemic seasons, Italy, 1969-2001. Emerg Infect Dis (2007) 1.22
Identification of potential conserved RNA secondary structure throughout influenza A coding regions. RNA (2011) 1.18
The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses. J Virol (2011) 1.16
Pandemic (H1N1) 2009 surveillance and prevalence of seasonal influenza, Singapore. Emerg Infect Dis (2010) 1.16
Age- and sex-related risk factors for influenza-associated mortality in the United States between 1997-2007. Am J Epidemiol (2013) 1.11
Influenza pandemic intervention planning using InfluSim: pharmaceutical and non- pharmaceutical interventions. BMC Infect Dis (2007) 1.10
Revised estimates of influenza-associated excess mortality, United States, 1995 through 2005. Emerg Themes Epidemiol (2008) 1.10
Changing attitudes toward influenza vaccination in U.S. Kidney transplant programs over the past decade. Clin J Am Soc Nephrol (2010) 1.08
NADPH oxidases: an overview from structure to innate immunity-associated pathologies. Cell Mol Immunol (2014) 1.08
Predicting pneumonia and influenza mortality from morbidity data. PLoS One (2007) 1.05
Population-level effects of suppressing fever. Proc Biol Sci (2014) 1.05
US flu mortality estimates are based on solid science. BMJ (2006) 1.02
Avian influenza viruses infect primary human bronchial epithelial cells unconstrained by sialic acid α2,3 residues. PLoS One (2011) 1.01
Synergistic TLR2/6 and TLR9 activation protects mice against lethal influenza pneumonia. PLoS One (2012) 1.00
Impact of pollution, climate, and sociodemographic factors on spatiotemporal dynamics of seasonal respiratory viruses. Clin Transl Sci (2011) 0.99
The impact of weather on influenza and pneumonia mortality in New York City, 1975-2002: a retrospective study. PLoS One (2012) 0.98
Influenza A virus coding regions exhibit host-specific global ordered RNA structure. PLoS One (2012) 0.96
Estimation of the health impact and cost-effectiveness of influenza vaccination with enhanced effectiveness in Canada. PLoS One (2011) 0.93
Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study. Crit Care (2010) 0.92
The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin. PLoS One (2012) 0.92
Rituximab-treated patients have a poor response to influenza vaccination. J Clin Immunol (2012) 0.92
Comparison of nasal and nasopharyngeal swabs for influenza detection in adults. Clin Med Res (2012) 0.90
Reassortment in segmented RNA viruses: mechanisms and outcomes. Nat Rev Microbiol (2016) 0.90
Differential localization and function of antibody-forming cells responsive to inactivated or live-attenuated influenza virus vaccines. Int Immunol (2012) 0.89
Burden of influenza in Latin America and the Caribbean: a systematic review and meta-analysis. Influenza Other Respir Viruses (2012) 0.87
High-mortality days during the winter season: comparing meteorological conditions across 5 US cities. Int J Biometeorol (2013) 0.86
Influenza mortality in the United States, 2009 pandemic: burden, timing and age distribution. PLoS One (2013) 0.86
Clinical features of novel 2009 influenza A (H1N1) infection in Isfahan, Iran. J Res Med Sci (2011) 0.86
Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34. Front Cell Infect Microbiol (2012) 0.84
Mortality attributable to seasonal influenza A and B infections in Thailand, 2005-2009: a longitudinal study. Am J Epidemiol (2015) 0.83
Effects of vaccination and population structure on influenza epidemic spread in the presence of two circulating strains. BMC Public Health (2011) 0.82
Triggering interventions for influenza: the ALERT algorithm. Clin Infect Dis (2014) 0.82
Influenza-Associated Excess Mortality in South Korea. Am J Prev Med (2015) 0.82
Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin. PLoS One (2014) 0.80
The immuno-regulatory impact of orally-administered Hypericum perforatum extract on Balb/C mice inoculated with H1n1 influenza A virus. PLoS One (2013) 0.80
Seasonal Influenza Infections and Cardiovascular Disease Mortality. JAMA Cardiol (2016) 0.80
Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations. Proc Natl Acad Sci U S A (2010) 0.78
Dynamically correlated mutations drive human Influenza A evolution. Sci Rep (2013) 0.78
A new look at an old virus: patterns of mutation accumulation in the human H1N1 influenza virus since 1918. Theor Biol Med Model (2012) 0.77
Modeling human influenza infection in the laboratory. Infect Drug Resist (2015) 0.77
Sarcandra glabra Extract Reduces the Susceptibility and Severity of Influenza in Restraint-Stressed Mice. Evid Based Complement Alternat Med (2012) 0.77
Pediatric influenza-associated deaths in new york state: death certificate coding and comparison to laboratory-confirmed deaths. Influenza Res Treat (2012) 0.77
Comparison of the effectiveness of antibody and cell-mediated immunity against inhaled and instilled influenza virus challenge. Virol J (2013) 0.75
Impact of Influenza on Outpatient Visits, Hospitalizations, and Deaths by Using a Time Series Poisson Generalized Additive Model. PLoS One (2016) 0.75
Zanamivir conjugated to poly-L-glutamine is much more active against influenza viruses in mice and ferrets than the drug itself. Pharm Res (2013) 0.75
Progress in developing virus-like particle influenza vaccines. Expert Rev Vaccines (2016) 0.75
A sigh of relief about treating influenza in individuals with alcohol-use disorders? Alcohol Clin Exp Res (2010) 0.75
Influenza newspaper reports and the influenza epidemic: an observational study in Fukuoka City, Japan. BMJ Open (2015) 0.75
Time series modeling of pathogen-specific disease probabilities with subsampled data. Biometrics (2016) 0.75
Beyond crystal balls: crosscutting solutions in global health to prepare for an unpredictable future. BMC Public Health (2015) 0.75
Mucosal antibody responses are directed by viral burden in children with acute influenza infection. Influenza Other Respir Viruses (2012) 0.75
M2SR, a novel live single replication influenza virus vaccine, provides effective heterosubtypic protection in mice. Vaccine (2016) 0.75
Synchrony, waves, and spatial hierarchies in the spread of influenza. Science (2006) 10.43
The genomic and epidemiological dynamics of human influenza A virus. Nature (2008) 10.26
Impact of influenza vaccination on seasonal mortality in the US elderly population. Arch Intern Med (2005) 8.46
Coding-sequence determinants of gene expression in Escherichia coli. Science (2009) 8.38
Surgical mask vs N95 respirator for preventing influenza among health care workers: a randomized trial. JAMA (2009) 7.61
Influenza in tropical regions. PLoS Med (2006) 6.82
Mortality benefits of influenza vaccination in elderly people: an ongoing controversy. Lancet Infect Dis (2007) 5.91
Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine (2005) 5.55
The signature features of influenza pandemics--implications for policy. N Engl J Med (2009) 5.37
Influenza and the winter increase in mortality in the United States, 1959-1999. Am J Epidemiol (2004) 5.26
Epidemiologic characterization of the 1918 influenza pandemic summer wave in Copenhagen: implications for pandemic control strategies. J Infect Dis (2008) 5.18
Multinational impact of the 1968 Hong Kong influenza pandemic: evidence for a smoldering pandemic. J Infect Dis (2005) 4.75
Epidemiological evidence of an early wave of the 1918 influenza pandemic in New York City. Proc Natl Acad Sci U S A (2005) 4.29
Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemic. Vaccine (2006) 4.28
Effect of influenza vaccination of children on infection rates in Hutterite communities: a randomized trial. JAMA (2010) 4.21
Seasonality of influenza in Brazil: a traveling wave from the Amazon to the subtropics. Am J Epidemiol (2007) 4.06
The population genetics of dN/dS. PLoS Genet (2008) 3.88
Stochastic processes are key determinants of short-term evolution in influenza a virus. PLoS Pathog (2006) 3.82
Dynamical resonance can account for seasonality of influenza epidemics. Proc Natl Acad Sci U S A (2004) 3.73
Cholera epidemic in Haiti, 2010: using a transmission model to explain spatial spread of disease and identify optimal control interventions. Ann Intern Med (2011) 3.62
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. J Invest Dermatol (2007) 3.58
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. PLoS Pathog (2008) 3.25
Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus. Biol Direct (2006) 3.18
A draft genome of Yersinia pestis from victims of the Black Death. Nature (2011) 3.18
Vaccination and the theory of games. Proc Natl Acad Sci U S A (2004) 2.89
Reassessing Google Flu Trends data for detection of seasonal and pandemic influenza: a comparative epidemiological study at three geographic scales. PLoS Comput Biol (2013) 2.85
Preliminary Estimates of Mortality and Years of Life Lost Associated with the 2009 A/H1N1 Pandemic in the US and Comparison with Past Influenza Seasons. PLoS Curr (2010) 2.77
Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel. J Am Acad Dermatol (2007) 2.71
Initial human transmission dynamics of the pandemic (H1N1) 2009 virus in North America. Influenza Other Respir Viruses (2009) 2.69
Improving the estimation of influenza-related mortality over a seasonal baseline. Epidemiology (2012) 2.68
Seed dispersal and spatial pattern in tropical trees. PLoS Biol (2006) 2.68
Demographic variability, vaccination, and the spatiotemporal dynamics of rotavirus epidemics. Science (2009) 2.67
Phylogenetic analysis reveals the global migration of seasonal influenza A viruses. PLoS Pathog (2007) 2.52
Group interest versus self-interest in smallpox vaccination policy. Proc Natl Acad Sci U S A (2003) 2.45
The early diversification of influenza A/H1N1pdm. PLoS Curr (2009) 2.44
Redundancy, antiredundancy, and the robustness of genomes. Proc Natl Acad Sci U S A (2002) 2.42
Prevalence of epistasis in the evolution of influenza A surface proteins. PLoS Genet (2011) 2.41
Characterizing the epidemiology of the 2009 influenza A/H1N1 pandemic in Mexico. PLoS Med (2011) 2.41
Natality decline and miscarriages associated with the 1918 influenza pandemic: the Scandinavian and United States experiences. J Infect Dis (2011) 2.33
Cross-protection between successive waves of the 1918-1919 influenza pandemic: epidemiological evidence from US Army camps and from Britain. J Infect Dis (2008) 2.29
Mutational robustness can facilitate adaptation. Nature (2010) 2.17
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death. Proc Natl Acad Sci U S A (2011) 2.15
Transients and attractors in epidemics. Proc Biol Sci (2003) 2.12
Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States. PLoS Pathog (2008) 2.09
Generality of the final size formula for an epidemic of a newly invading infectious disease. Bull Math Biol (2006) 2.08
Rate-limiting steps in yeast protein translation. Cell (2013) 1.99
Nontuberculous mycobacteria-associated lung disease in hospitalized persons, United States, 1998-2005. Emerg Infect Dis (2009) 1.91
Inferring the dynamics of diversification: a coalescent approach. PLoS Biol (2010) 1.91
Mortality burden of the A/H1N1 pandemic in Mexico: a comparison of deaths and years of life lost to seasonal influenza. Clin Infect Dis (2011) 1.87
Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates. PLoS Pathog (2009) 1.85
Latitudinal variations in seasonal activity of influenza and respiratory syncytial virus (RSV): a global comparative review. PLoS One (2013) 1.84
Mortality patterns associated with the 1918 influenza pandemic in Mexico: evidence for a spring herald wave and lack of preexisting immunity in older populations. J Infect Dis (2010) 1.78
Reinforcement of pre-zygotic isolation and karyotype evolution in Agrodiaetus butterflies. Nature (2005) 1.76
Aging and gene expression in the primate brain. PLoS Biol (2005) 1.76
Vaccinating to protect a vulnerable subpopulation. PLoS Med (2007) 1.76
Reconciling molecular phylogenies with the fossil record. Proc Natl Acad Sci U S A (2011) 1.72
Prioritization of influenza pandemic vaccination to minimize years of life lost. J Infect Dis (2008) 1.69
Influenza-associated mortality in temperate and subtropical Chinese cities, 2003-2008. Bull World Health Organ (2012) 1.69
Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration. Hum Mol Genet (2008) 1.68
Extortion and cooperation in the Prisoner's Dilemma. Proc Natl Acad Sci U S A (2012) 1.62
Elevated influenza-related excess mortality in South African elderly individuals, 1998-2005. Clin Infect Dis (2010) 1.62
The dynamics of adaptation on correlated fitness landscapes. Proc Natl Acad Sci U S A (2009) 1.61
Using protein complexes to predict phenotypic effects of gene mutation. Genome Biol (2007) 1.57
Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003. J Infect Dis (2007) 1.51
Air travel and the spread of influenza: important caveats. PLoS Med (2006) 1.49
Immune history shapes specificity of pandemic H1N1 influenza antibody responses. J Exp Med (2013) 1.47
From extortion to generosity, evolution in the Iterated Prisoner's Dilemma. Proc Natl Acad Sci U S A (2013) 1.46
Assessing the burden of paediatric influenza in Europe: the European Paediatric Influenza Analysis (EPIA) project. Eur J Pediatr (2010) 1.44
Consequences of defaunation for a tropical tree community. Ecol Lett (2013) 1.42
Description of a rule-based system for the i2b2 challenge in natural language processing for clinical data. J Am Med Inform Assoc (2009) 1.40
A statistical theory for sampling species abundances. Ecol Lett (2007) 1.40
Evolution, safety, and highly pathogenic influenza viruses. Science (2012) 1.36
Spatial and temporal characteristics of the 2009 A/H1N1 influenza pandemic in Peru. PLoS One (2011) 1.35
Interactions between the immune system and cancer: a brief review of non-spatial mathematical models. Bull Math Biol (2010) 1.33
Influenza-related mortality in the Italian elderly: no decline associated with increasing vaccination coverage. Vaccine (2006) 1.31
Reduction in gastroenteritis in United States children and correlation with early rotavirus vaccine uptake from national medical claims databases. Pediatr Infect Dis J (2010) 1.30
Multiple transmission pathways and disease dynamics in a waterborne pathogen model. Bull Math Biol (2010) 1.30
Mortality burden of the 2009 A/H1N1 influenza pandemic in France: comparison to seasonal influenza and the A/H3N2 pandemic. PLoS One (2012) 1.29
The reproduction number of seasonal influenza epidemics in Brazil, 1996-2006. Proc Biol Sci (2010) 1.28
Epidemiological characterization of a fourth wave of pandemic A/H1N1 influenza in Mexico, winter 2011-2012: age shift and severity. Arch Med Res (2012) 1.25
Influenza vaccination and mortality benefits: new insights, new opportunities. Vaccine (2009) 1.24
Influenza-related mortality among adults aged 25-54 years with AIDS in South Africa and the United States of America. Clin Infect Dis (2012) 1.24
1951 influenza epidemic, England and Wales, Canada, and the United States. Emerg Infect Dis (2006) 1.23
Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United States. J Virol (2010) 1.23
The polymorphism frequency spectrum of finitely many sites under selection. Genetics (2008) 1.22
The influence of climatic conditions on the transmission dynamics of the 2009 A/H1N1 influenza pandemic in Chile. BMC Infect Dis (2012) 1.22
Trends for influenza-related deaths during pandemic and epidemic seasons, Italy, 1969-2001. Emerg Infect Dis (2007) 1.22