Published in BMJ on January 21, 2006
Influenza in tropical regions. PLoS Med (2006) 6.82
Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA (2003) 31.71
Impact of influenza vaccination on seasonal mortality in the US elderly population. Arch Intern Med (2005) 8.46
The impact of influenza epidemics on mortality: introducing a severity index. Am J Public Health (1997) 7.81
Mortality due to influenza in the United States--an annualized regression approach using multiple-cause mortality data. Am J Epidemiol (2005) 3.58
Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform (2008) 71.12
Synchrony, waves, and spatial hierarchies in the spread of influenza. Science (2006) 10.43
The genomic and epidemiological dynamics of human influenza A virus. Nature (2008) 10.26
Impact of influenza vaccination on seasonal mortality in the US elderly population. Arch Intern Med (2005) 8.46
Influenza in tropical regions. PLoS Med (2006) 6.82
Mortality benefits of influenza vaccination in elderly people: an ongoing controversy. Lancet Infect Dis (2007) 5.91
Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine (2005) 5.55
The signature features of influenza pandemics--implications for policy. N Engl J Med (2009) 5.37
Influenza and the winter increase in mortality in the United States, 1959-1999. Am J Epidemiol (2004) 5.26
Epidemiologic characterization of the 1918 influenza pandemic summer wave in Copenhagen: implications for pandemic control strategies. J Infect Dis (2008) 5.18
Multinational impact of the 1968 Hong Kong influenza pandemic: evidence for a smoldering pandemic. J Infect Dis (2005) 4.75
Epidemiological evidence of an early wave of the 1918 influenza pandemic in New York City. Proc Natl Acad Sci U S A (2005) 4.29
Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemic. Vaccine (2006) 4.28
Seasonality of influenza in Brazil: a traveling wave from the Amazon to the subtropics. Am J Epidemiol (2007) 4.06
Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus. Proc Natl Acad Sci U S A (2002) 4.02
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809. Proc Natl Acad Sci U S A (2011) 3.87
Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program Study. Clin Infect Dis (2009) 3.86
Stochastic processes are key determinants of short-term evolution in influenza a virus. PLoS Pathog (2006) 3.82
Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med (2004) 3.61
Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules. Am J Physiol Lung Cell Mol Physiol (2006) 3.59
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. J Invest Dermatol (2007) 3.58
Mortality due to influenza in the United States--an annualized regression approach using multiple-cause mortality data. Am J Epidemiol (2005) 3.58
The risk of a mosquito-borne infection in a heterogeneous environment. PLoS Biol (2004) 3.46
Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum. Nature (2004) 3.46
Transmission dynamics and prospects for the elimination of canine rabies. PLoS Biol (2009) 3.38
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. PLoS Pathog (2008) 3.25
Enteric infections, diarrhea, and their impact on function and development. J Clin Invest (2008) 3.23
Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virus. Biol Direct (2006) 3.18
The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains. Autophagy (2007) 3.14
Cutting edge: TREM-2 attenuates macrophage activation. J Immunol (2006) 3.07
Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99
Surgical intervention in childhood intermittent exotropia: current practice and clinical outcomes from an observational cohort study. Br J Ophthalmol (2012) 2.92
Reassessing Google Flu Trends data for detection of seasonal and pandemic influenza: a comparative epidemiological study at three geographic scales. PLoS Comput Biol (2013) 2.85
Preliminary Estimates of Mortality and Years of Life Lost Associated with the 2009 A/H1N1 Pandemic in the US and Comparison with Past Influenza Seasons. PLoS Curr (2010) 2.77
Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel. J Am Acad Dermatol (2007) 2.71
Initial human transmission dynamics of the pandemic (H1N1) 2009 virus in North America. Influenza Other Respir Viruses (2009) 2.69
Improving the estimation of influenza-related mortality over a seasonal baseline. Epidemiology (2012) 2.68
Demographic variability, vaccination, and the spatiotemporal dynamics of rotavirus epidemics. Science (2009) 2.67
The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance. Mol Biol Evol (2007) 2.59
Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: resistance is a regional problem. Proc Natl Acad Sci U S A (2004) 2.57
Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virus. Proc Natl Acad Sci U S A (2003) 2.54
Phylogenetic analysis reveals the global migration of seasonal influenza A viruses. PLoS Pathog (2007) 2.52
The early diversification of influenza A/H1N1pdm. PLoS Curr (2009) 2.44
Native bees provide insurance against ongoing honey bee losses. Ecol Lett (2007) 2.43
Effects of school closure on incidence of pandemic influenza in Alberta, Canada. Ann Intern Med (2012) 2.42
Prevalence of epistasis in the evolution of influenza A surface proteins. PLoS Genet (2011) 2.41
Characterizing the epidemiology of the 2009 influenza A/H1N1 pandemic in Mexico. PLoS Med (2011) 2.41
Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst (2009) 2.34
Synchronous cycles of domestic dog rabies in sub-Saharan Africa and the impact of control efforts. Proc Natl Acad Sci U S A (2007) 2.34
Natality decline and miscarriages associated with the 1918 influenza pandemic: the Scandinavian and United States experiences. J Infect Dis (2011) 2.33
A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission. Malar J (2004) 2.29
Cross-protection between successive waves of the 1918-1919 influenza pandemic: epidemiological evidence from US Army camps and from Britain. J Infect Dis (2008) 2.29
In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. J Exp Med (2005) 2.21
Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States. PLoS Pathog (2008) 2.09
Extra-couple HIV transmission in sub-Saharan Africa: a mathematical modelling study of survey data. Lancet (2013) 2.03
The combined effects of pathogens and predators on insect outbreaks. Nature (2004) 2.03
Exploring reservoir dynamics: a case study of rabies in the Serengeti ecosystem. J Appl Ecol (2008) 1.98
Network metrics reveal differences in social organization between two fission-fusion species, Grevy's zebra and onager. Oecologia (2006) 1.95
Nontuberculous mycobacteria-associated lung disease in hospitalized persons, United States, 1998-2005. Emerg Infect Dis (2009) 1.91
Agricultural intensification, priming for persistence and the emergence of Nipah virus: a lethal bat-borne zoonosis. J R Soc Interface (2011) 1.89
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin. Nat Immunol (2009) 1.88
Mortality burden of the A/H1N1 pandemic in Mexico: a comparison of deaths and years of life lost to seasonal influenza. Clin Infect Dis (2011) 1.87
Rabies exposures, post-exposure prophylaxis and deaths in a region of endemic canine rabies. PLoS Negl Trop Dis (2008) 1.84
Latitudinal variations in seasonal activity of influenza and respiratory syncytial virus (RSV): a global comparative review. PLoS One (2013) 1.84
Fecal markers of intestinal inflammation and permeability associated with the subsequent acquisition of linear growth deficits in infants. Am J Trop Med Hyg (2012) 1.83
Mortality patterns associated with the 1918 influenza pandemic in Mexico: evidence for a spring herald wave and lack of preexisting immunity in older populations. J Infect Dis (2010) 1.78
Vaccinating to protect a vulnerable subpopulation. PLoS Med (2007) 1.76
Autophagy and the degradation of mitochondria. Mitochondrion (2010) 1.75
Influenza-associated mortality in temperate and subtropical Chinese cities, 2003-2008. Bull World Health Organ (2012) 1.69
Prioritization of influenza pandemic vaccination to minimize years of life lost. J Infect Dis (2008) 1.69
Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial. Clin Infect Dis (2003) 1.67
Elevated influenza-related excess mortality in South African elderly individuals, 1998-2005. Clin Infect Dis (2010) 1.62
Robust estimation of microbial diversity in theory and in practice. ISME J (2013) 1.58
Base deficit from the first peripheral venous sample: a surrogate for arterial base deficit in the trauma bay. J Trauma (2011) 1.52
Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003. J Infect Dis (2007) 1.51
Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement. Environ Health Perspect (2016) 1.50
Air travel and the spread of influenza: important caveats. PLoS Med (2006) 1.49
Assessing the burden of paediatric influenza in Europe: the European Paediatric Influenza Analysis (EPIA) project. Eur J Pediatr (2010) 1.44
Reducing stunting among children: the potential contribution of diagnostics. Nature (2006) 1.44
Description of a rule-based system for the i2b2 challenge in natural language processing for clinical data. J Am Med Inform Assoc (2009) 1.40
An open letter to the Executive Board of WHO. Lancet (2002) 1.39
Evolution, safety, and highly pathogenic influenza viruses. Science (2012) 1.36
Structure of the exosporium and sublayers of spores of the Bacillus cereus family revealed by electron crystallography. Mol Microbiol (2008) 1.35
Spatial and temporal characteristics of the 2009 A/H1N1 influenza pandemic in Peru. PLoS One (2011) 1.35
Estimates of mortality attributable to influenza and RSV in the United States during 1997-2009 by influenza type or subtype, age, cause of death, and risk status. Influenza Other Respir Viruses (2014) 1.35
Widespread outbreak of norovirus gastroenteritis among evacuees of Hurricane Katrina residing in a large "megashelter" in Houston, Texas: lessons learned for prevention. Clin Infect Dis (2007) 1.34
Antidepressant use in black and white populations in the United States. Psychiatr Serv (2008) 1.33
Effects of low-load resistance training combined with blood flow restriction or hypoxia on muscle function and performance in netball athletes. J Sci Med Sport (2012) 1.32
Agricultural antibiotics and human health. PLoS Med (2005) 1.31