A community-wide outbreak of legionnaires disease linked to industrial cooling towers--how far can contaminated aerosols spread?

PubWeight™: 2.38‹?› | Rank: Top 2%

🔗 View Article (PMID 16323138)

Published in J Infect Dis on November 28, 2005

Authors

Tran Minh Nhu Nguyen1, Daniele Ilef, Sophie Jarraud, Laurence Rouil, Christine Campese, Didier Che, Sylvie Haeghebaert, Francois Ganiayre, Frederic Marcel, Jerome Etienne, Jean-Claude Desenclos

Author Affiliations

1: Institut de Veille Sanitaire and European Programme for Intervention Epidemiology Training, Saint-Maurice, France. nguyen.tran.minh@ktl.fi

Articles citing this

Molecular pathogenesis of infections caused by Legionella pneumophila. Clin Microbiol Rev (2010) 2.04

Aggravating genetic interactions allow a solution to redundancy in a bacterial pathogen. Science (2012) 1.87

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion. Proc Natl Acad Sci U S A (2011) 1.50

Occurrence and distribution of sequence types among Legionella pneumophila strains isolated from patients in Germany: common features and differences to other regions of the world. Eur J Clin Microbiol Infect Dis (2008) 1.18

Epidemiology and Ecology of Opportunistic Premise Plumbing Pathogens: Legionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa. Environ Health Perspect (2015) 1.14

A community outbreak of Legionnaires' disease associated with a cooling tower in Vic and Gurb, Catalonia (Spain) in 2005. Eur J Clin Microbiol Infect Dis (2008) 1.08

Evaluation of a nested-PCR-derived sequence-based typing method applied directly to respiratory samples from patients with Legionnaires' disease. J Clin Microbiol (2009) 1.08

Restaurant outbreak of Legionnaires' disease associated with a decorative fountain: an environmental and case-control study. BMC Infect Dis (2007) 1.04

A large Legionnaires' disease outbreak in Pamplona, Spain: early detection, rapid control and no case fatality. Epidemiol Infect (2007) 0.94

Airborne Transmission of Melioidosis to Humans from Environmental Aerosols Contaminated with B. pseudomallei. PLoS Negl Trop Dis (2015) 0.90

Two Legionnaires' disease cases associated with industrial waste water treatment plants: a case report. BMC Infect Dis (2010) 0.89

Improved correlation of human Q fever incidence to modelled C. burnetii concentrations by means of an atmospheric dispersion model. Int J Health Geogr (2015) 0.87

Legionella bacteria in aerosols: sampling and analytical approaches used during the legionnaires disease outbreak in Pas-de-Calais. J Infect Dis (2006) 0.86

Potential role of bacteria packaging by protozoa in the persistence and transmission of pathogenic bacteria. Front Microbiol (2014) 0.86

Presence of Legionella and free-living Amoebae in composts and bioaerosols from composting facilities. PLoS One (2013) 0.85

A model for the early identification of sources of airborne pathogens in an outdoor environment. PLoS One (2013) 0.85

Uncertainties associated with assessing the public health risk from Legionella. Front Microbiol (2014) 0.84

Free-living amoebae (FLA) co-occurring with legionellae in industrial waters. Eur J Protistol (2014) 0.84

Molecular Detection of Legionella: Moving on From mip. Front Microbiol (2010) 0.83

Prevalence and Molecular Characteristics of Waterborne Pathogen Legionella in Industrial Cooling Tower Environments. Int J Environ Res Public Health (2015) 0.82

Public health and economic costs of investigating a suspected outbreak of Legionnaires' disease. Epidemiol Infect (2007) 0.82

Role of bacterial adhesion in the microbial ecology of biofilms in cooling tower systems. Biofouling (2009) 0.82

Outdoor environments and human pathogens in air. Environ Health (2009) 0.82

Wind-Mediated Spread of Low-Pathogenic Avian Influenza Virus into the Environment during Outbreaks at Commercial Poultry Farms. PLoS One (2015) 0.81

Sporadic community-acquired Legionnaires' disease in France: a 2-year national matched case-control study. Epidemiol Infect (2008) 0.81

Molecular diversity and high virulence of Legionella pneumophila strains isolated from biofilms developed within a warm spring of a thermal spa. BMC Microbiol (2013) 0.81

Detection of Legionella spp. from Domestic Water in the Prefecture of Arta, Greece. J Pathog (2014) 0.80

Seroepidemiological study after a long-distance industrial outbreak of legionnaires' disease. Clin Vaccine Immunol (2009) 0.80

Legionella antibodies in a Danish hospital staff with known occupational exposure. J Environ Public Health (2009) 0.79

A review of back-calculation techniques and their potential to inform mitigation strategies with application to non-transmissible acute infectious diseases. J R Soc Interface (2015) 0.79

Legionnaires' disease from a cooling tower in a community outbreak in Lidköping, Sweden- epidemiological, environmental and microbiological investigation supported by meteorological modelling. BMC Infect Dis (2012) 0.79

Spatial Targeting for Bovine Tuberculosis Control: Can the Locations of Infected Cattle Be Used to Find Infected Badgers? PLoS One (2015) 0.78

Lesser-known or hidden reservoirs of infection and implications for adequate prevention strategies: Where to look and what to look for. GMS Hyg Infect Control (2015) 0.76

Strategies for controlling non-transmissible infection outbreaks using a large human movement data set. PLoS Comput Biol (2014) 0.76

Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection. Small GTPases (2014) 0.76

Spatial arrangement of legionella colonies in intact biofilms from a model cooling water system. Microbiol Insights (2013) 0.76

Free-living amoebae and their associated bacteria in Austrian cooling towers: a 1-year routine screening. Parasitol Res (2016) 0.76

Influence of climate and geography on the occurrence of Legionella and amoebae in composting facilities. BMC Res Notes (2014) 0.75

Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase. PeerJ (2016) 0.75

Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila. Infect Immun (2016) 0.75

Long-range dispersal moved Francisella tularensis into Western Europe from the East. Microb Genom (2016) 0.75

Unusual Legionnaires' outbreak in cool, dry Western Canada: an investigation using genomic epidemiology. Epidemiol Infect (2016) 0.75

Structural and thermodynamic insight into phenylalanine hydroxylase from the human pathogen Legionella pneumophila. FEBS Open Bio (2013) 0.75

Bioaerosol generation by raindrops on soil. Nat Commun (2017) 0.75

Articles by these authors

Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis (2003) 13.83

Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA (2003) 12.04

Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet (2002) 10.26

Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun (2002) 7.34

Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science (2007) 7.06

Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob Agents Chemother (2006) 7.03

Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin Infect Dis (2002) 5.75

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat Genet (2004) 4.93

Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission. Lancet (2013) 4.57

Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA (2002) 4.48

A major epidemic of chikungunya virus infection on Reunion Island, France, 2005-2006. Am J Trop Med Hyg (2007) 4.18

Global distribution of Panton-Valentine leukocidin--positive methicillin-resistant Staphylococcus aureus, 2006. Emerg Infect Dis (2007) 3.98

Bacterial competition for human nasal cavity colonization: role of Staphylococcal agr alleles. Appl Environ Microbiol (2003) 3.51

Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin. Clin Infect Dis (2007) 3.31

Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila. J Clin Microbiol (2005) 3.21

Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05

Population-based HIV-1 incidence in France, 2003-08: a modelling analysis. Lancet Infect Dis (2010) 3.01

Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression. EMBO J (2005) 2.95

Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils. J Clin Invest (2005) 2.82

Increasing incidence of zygomycosis (mucormycosis), France, 1997-2006. Emerg Infect Dis (2009) 2.33

Antimicrobial resistance in commensal flora of pig farmers. Emerg Infect Dis (2004) 1.95

Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans? J Infect Dis (2010) 1.92

Clinical and environmental distributions of Legionella strains in France are different. J Clin Microbiol (2004) 1.91

Molecular diagnosis of infective endocarditis by PCR amplification and direct sequencing of DNA from valve tissue. J Clin Microbiol (2003) 1.90

Mortality related to chronic hepatitis B and chronic hepatitis C in France: evidence for the role of HIV coinfection and alcohol consumption. J Hepatol (2007) 1.87

Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. Antimicrob Agents Chemother (2007) 1.84

Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species. Genome Res (2008) 1.84

Studies needed to address public health challenges of the 2009 H1N1 influenza pandemic: insights from modeling. PLoS Med (2010) 1.83

Harm reduction interventions, behaviours and associated health outcomes in France, 1996-2003. Addiction (2005) 1.80

High genetic variability of the agr locus in Staphylococcus species. J Bacteriol (2002) 1.78

Development and validation of an immunoassay for identification of recent human immunodeficiency virus type 1 infections and its use on dried serum spots. J Clin Microbiol (2005) 1.77

Neutralization of Staphylococcus aureus Panton Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis (2004) 1.76

Pediatric bone and joint infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus. Pediatr Infect Dis J (2007) 1.64

A multicenter evaluation of genotypic methods for the epidemiologic typing of Legionella pneumophila serogroup 1: results of a pan-European study. Clin Microbiol Infect (1999) 1.61

Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections. J Clin Microbiol (2003) 1.61

Increase of Neisseria gonorrhoeae ciprofloxacin resistance in France in 2001-2003. Sex Transm Dis (2006) 1.60

Cost-effectiveness of HIV post-exposure prophylaxis in France. AIDS (2006) 1.58

Virulence determinants in community and hospital meticillin-resistant Staphylococcus aureus. J Hosp Infect (2007) 1.57

Global distribution and evolution of Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus, 1981-2007. J Infect Dis (2010) 1.54

Comparative prevalence of superantigen genes in Staphylococcus aureus isolates causing sepsis with and without septic shock. Clin Infect Dis (2005) 1.53

Trends in residual risk of transfusion-transmitted viral infections in France between 1992 and 2000. Transfusion (2002) 1.53

Community-acquired methicillin-resistant Staphylococcus aureus isolated in Switzerland contains the Panton-Valentine leukocidin or exfoliative toxin genes. J Clin Microbiol (2004) 1.48

A history of Panton-Valentine leukocidin (PVL)-associated infection protects against death in PVL-associated pneumonia. Vaccine (2011) 1.48

Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS One (2009) 1.48

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS Genet (2010) 1.46

Detection of new methicillin-resistant Staphylococcus aureus clones containing the toxic shock syndrome toxin 1 gene responsible for hospital- and community-acquired infections in France. J Clin Microbiol (2006) 1.46

Quantitative real-time Legionella PCR for environmental water samples: data interpretation. Appl Environ Microbiol (2006) 1.44

Prevalence of hepatitis B and hepatitis C virus infections in France in 2004: social factors are important predictors after adjusting for known risk factors. J Med Virol (2010) 1.43

Identification of the capsular polysaccharides in Staphylococcus aureus clinical isolates by PCR and agglutination tests. J Clin Microbiol (2007) 1.40

Risk factors for leptospirosis in metropolitan France: results of a national case-control study, 1999-2000. Clin Infect Dis (2004) 1.39

Methicillin-resistant Staphylococcus capitis with reduced vancomycin susceptibility causes late-onset sepsis in intensive care neonates. PLoS One (2012) 1.37

Epidemiology of invasive methicillin-resistant Staphylococcus aureus clones collected in France in 2006 and 2007. J Clin Microbiol (2008) 1.35

Inactivation of mprF affects vancomycin susceptibility in Staphylococcus aureus. Biochim Biophys Acta (2003) 1.35

Methicillin-resistant Staphylococcus aureus in neonatal intensive care unit. Emerg Infect Dis (2005) 1.32

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes. BMC Genomics (2011) 1.32

Sociodemographic factors that contribute to the development of extrapulmonary tuberculosis were identified. J Clin Epidemiol (2005) 1.30

VEB-1 Extended-spectrum beta-lactamase-producing Acinetobacter baumannii, France. Emerg Infect Dis (2006) 1.29

Pneumonia and new methicillin-resistant Staphylococcus aureus clone. Emerg Infect Dis (2006) 1.28

Clonal distribution and differential occurrence of the enterotoxin gene cluster, egc, in carriage- versus bacteremia-associated isolates of Staphylococcus aureus. J Clin Microbiol (2006) 1.27

Lethal necrotizing pneumonia caused by an ST398 Staphylococcus aureus strain. Emerg Infect Dis (2010) 1.26

A multicenter evaluation of the Biotest legionella urinary antigen EIA. Clin Microbiol Infect (1998) 1.26

Incidence of listeriosis and related mortality among groups at risk of acquiring listeriosis. Clin Infect Dis (2011) 1.26

Population-based analysis of invasive fungal infections, France, 2001-2010. Emerg Infect Dis (2014) 1.25

Panton-Valentine leukocidin: a marker of severity for Staphylococcus aureus infection? Clin Infect Dis (2005) 1.25

Clinical and environmental isolates of Legionella pneumophila serogroup 1 cannot be distinguished by sequence analysis of two surface protein genes and three housekeeping genes. Appl Environ Microbiol (2005) 1.25

Staphylococcal enterotoxin-like toxins U2 and V, two new staphylococcal superantigens arising from recombination within the enterotoxin gene cluster. Infect Immun (2006) 1.24

A PCR-based method for monitoring Legionella pneumophila in water samples detects viable but noncultivable legionellae that can recover their cultivability. Appl Environ Microbiol (2008) 1.22

Detection of methicillin-resistant Staphylococcus aureus strains resistant to multiple antibiotics and carrying the Panton-Valentine leukocidin genes in an Algiers hospital. Antimicrob Agents Chemother (2006) 1.22

Panton-Valentine leukocidin does play a role in the early stage of Staphylococcus aureus skin infections: a rabbit model. PLoS One (2011) 1.22

Immunogenicity of toxins during Staphylococcus aureus infection. Clin Infect Dis (2010) 1.20

French national program for prevention of healthcare-associated infections and antimicrobial resistance, 1992-2008: positive trends, but perseverance needed. Infect Control Hosp Epidemiol (2009) 1.17

Outbreak of hepatitis C virus infection in a hemodialysis unit: potential transmission by the hemodialysis machine? Infect Control Hosp Epidemiol (2002) 1.17

Staphylococcus aureus isolates associated with necrotizing pneumonia bind to basement membrane type I and IV collagens and laminin. J Infect Dis (2004) 1.16

Frequent carriage of Panton-Valentine leucocidin genes by Staphylococcus aureus isolates from surgically drained abscesses. J Clin Microbiol (2005) 1.15

Clonal complexes and virulence factors of Staphylococcus aureus from several cities in India. BMC Microbiol (2012) 1.14

Legionella pneumophila serogroup 1 strain Paris: endemic distribution throughout France. J Clin Microbiol (2003) 1.14

Beta-lactams interfering with PBP1 induce Panton-Valentine leukocidin expression by triggering sarA and rot global regulators of Staphylococcus aureus. Antimicrob Agents Chemother (2011) 1.12

Hepatitis C virus genotype 3 and the risk of severe liver disease in a large population of drug users in France. J Med Virol (2010) 1.11

Surveillance of hemolytic uremic syndrome in children less than 15 years of age, a system to monitor O157 and non-O157 Shiga toxin-producing Escherichia coli infections in France, 1996-2006. Pediatr Infect Dis J (2008) 1.11

Clinical manifestations of staphylococcal scalded-skin syndrome depend on serotypes of exfoliative toxins. J Clin Microbiol (2005) 1.11

Integrated real-time PCR for detection and monitoring of Legionella pneumophila in water systems. Appl Environ Microbiol (2006) 1.10

Toxin gene content of the Lyon methicillin-resistant Staphylococcus aureus clone compared with that of other pandemic clones. J Clin Microbiol (2006) 1.10

Introduction of SARS in France, March-April, 2003. Emerg Infect Dis (2004) 1.10

Different transmission patterns in the early stages of the influenza A(H1N1)v pandemic: a comparative analysis of 12 European countries. Epidemics (2011) 1.10

Effects of subinhibitory concentrations of antibiotics on virulence factor expression by community-acquired methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother (2013) 1.09

Population diversity of Staphylococcus intermedius isolates from various host species: typing by 16S-23S intergenic ribosomal DNA spacer polymorphism analysis. J Clin Microbiol (2002) 1.09

Comparative inflammatory properties of staphylococcal superantigenic enterotoxins SEA and SEG: implications for septic shock. J Leukoc Biol (2006) 1.09

Influenza pandemic preparedness in France: modelling the impact of interventions. J Epidemiol Community Health (2006) 1.09