Staphylococcal enterotoxin-like toxins U2 and V, two new staphylococcal superantigens arising from recombination within the enterotoxin gene cluster.

PubWeight™: 1.24‹?› | Rank: Top 10%

🔗 View Article (PMC 1539601)

Published in Infect Immun on August 01, 2006

Authors

Damien Yann Thomas1, Sophie Jarraud, Brigitte Lemercier, Gregoire Cozon, Klara Echasserieau, Jerome Etienne, Marie-Lise Gougeon, Gerard Lina, François Vandenesch

Author Affiliations

1: INSERM, E0230, Lyon, France.

Articles citing this

Food poisoning and Staphylococcus aureus enterotoxins. Toxins (Basel) (2010) 1.84

Identification and characterization of two novel staphylococcal enterotoxins, types S and T. Infect Immun (2008) 1.38

The formation of Staphylococcus aureus enterotoxin in food environments and advances in risk assessment. Virulence (2011) 1.19

Multiple roles of Staphylococcus aureus enterotoxins: pathogenicity, superantigenic activity, and correlation to antibiotic resistance. Toxins (Basel) (2010) 1.10

Staphylococcus aureus superantigens elicit redundant and extensive human Vbeta patterns. Infect Immun (2009) 1.06

How should staphylococcal food poisoning outbreaks be characterized? Toxins (Basel) (2010) 0.97

Characterization of Staphylococcus aureus strains associated with food poisoning in Shenzhen, China. Appl Environ Microbiol (2012) 0.97

Emetic potentials of newly identified staphylococcal enterotoxin-like toxins. Infect Immun (2013) 0.95

Rauvolfia grandiflora (apocynaceae) extract interferes with staphylococcal density, enterotoxin production and antimicrobial activity. Braz J Microbiol (2010) 0.93

Acetic acid increases the phage-encoded enterotoxin A expression in Staphylococcus aureus. BMC Microbiol (2010) 0.90

Identification and Characterization of a Novel Staphylococcal Emetic Toxin. Appl Environ Microbiol (2015) 0.89

Genotypes, exotoxin gene content, and antimicrobial resistance of Staphylococcus aureus strains recovered from foods and food handlers. Appl Environ Microbiol (2012) 0.89

Detection of classical and newly described staphylococcal superantigen genes in coagulase-negative staphylococci isolated from bovine intramammary infections. Vet Microbiol (2010) 0.87

Phage-mediated horizontal transfer of a Staphylococcus aureus virulence-associated genomic island. Sci Rep (2015) 0.84

spa typing and enterotoxin gene profile of Staphylococcus aureus isolated from bovine raw milk in Korea. J Vet Sci (2010) 0.83

Molecular epidemiology and identification of a Staphylococcus aureus clone causing food poisoning outbreaks in Japan. J Clin Microbiol (2014) 0.83

Construction of a single-chain variable-fragment antibody against the superantigen Staphylococcal enterotoxin B. Appl Environ Microbiol (2010) 0.82

Screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis. PLoS One (2010) 0.80

Detection of the staphylococcal enterotoxin D-like gene from staphylococcal food poisoning isolates over the last two decades in Tokyo. J Vet Med Sci (2015) 0.77

Genotypic and phenotypic analysis of clinical isolates of Staphylococcus aureus revealed production patterns and hemolytic potentials unlinked to gene profiles and source. BMC Microbiol (2016) 0.77

A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus. Mol Microbiol (2016) 0.75

Enterotoxin Gene Cluster-Encoded SEI and SElN from Staphylococcus aureus Isolates are Crucial for the Induction of Human Blood Cell Proliferation and Pathogenicity in Rabbits. Toxins (Basel) (2016) 0.75

Safety Evaluation of the Coagulase-Negative Staphylococci Microbiota of Salami: Superantigenic Toxin Production and Antimicrobial Resistance. Biomed Res Int (2015) 0.75

Articles cited by this

Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55

Genome and virulence determinants of high virulence community-acquired MRSA. Lancet (2002) 14.64

The staphylococcal enterotoxins and their relatives. Science (1990) 11.99

Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A (2004) 8.95

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48

Exotoxins of Staphylococcus aureus. Clin Microbiol Rev (2000) 7.35

The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell (1989) 7.02

V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci U S A (1993) 4.97

Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus. Infect Immun (2002) 4.62

Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol (2001) 4.48

Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC. Drug Resist Updat (2003) 4.40

egc, a highly prevalent operon of enterotoxin gene, forms a putative nursery of superantigens in Staphylococcus aureus. J Immunol (2001) 4.36

Pathogenicity islands in bacterial pathogenesis. Clin Microbiol Rev (2004) 3.77

Staphylococcus aureus: superbug, super genome? Trends Microbiol (2004) 3.53

Characterization of a putative pathogenicity island from bovine Staphylococcus aureus encoding multiple superantigens. J Bacteriol (2001) 2.84

Bacterial superantigens. Clin Exp Immunol (2003) 2.42

The structural basis of T cell activation by superantigens. Annu Rev Immunol (1999) 2.34

Prevalence of genes encoding pyrogenic toxin superantigens and exfoliative toxins among strains of Staphylococcus aureus isolated from blood and nasal specimens. J Clin Microbiol (2003) 2.27

Identification and characterization of staphylococcal enterotoxin types G and I from Staphylococcus aureus. Infect Immun (1998) 2.22

Identification of a novel gene cluster encoding staphylococcal exotoxin-like proteins: characterization of the prototypic gene and its protein product, SET1. Infect Immun (2000) 2.07

Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus. Plasmid (2003) 2.04

Standard nomenclature for the superantigens expressed by Staphylococcus. J Infect Dis (2004) 1.78

Identification of a new putative enterotoxin SEU encoded by the egc cluster of Staphylococcus aureus. J Appl Microbiol (2003) 1.68

Combination of MHC-peptide multimer-based T cell sorting with the Immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses. J Immunol Methods (2002) 1.57

Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC. J Immunol (1990) 1.54

Comprehensive analysis of classical and newly described staphylococcal superantigenic toxin genes in Staphylococcus aureus isolates. FEMS Microbiol Lett (2005) 1.49

Anergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivo. J Exp Med (1999) 1.24

High prevalence of superantigens associated with the egc locus in Staphylococcus aureus isolates from patients with atopic eczema. Eur J Clin Microbiol Infect Dis (2003) 1.10

PCR detection of staphylococcal enterotoxin genes in Staphylococcus spp. strains isolated from meat and dairy products. Evidence for new variants of seG and seI in S. aureus AB-8802. J Appl Microbiol (2004) 1.10

Characterization of novel staphylococcal enterotoxin-like toxin type P. Infect Immun (2005) 1.09

Staphylococcal superantigens: do they play a role in sepsis? Arch Immunol Ther Exp (Warsz) (2005) 1.07

Superantigen bacterial toxins: state of the art. Toxicon (2001) 1.01

Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes. J Immunol (2003) 0.98

Biological properties of staphylococcal enterotoxin-like toxin type R. Infect Immun (2004) 0.92

Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule. Mol Immunol (2005) 0.92

Relationships between toxin gene content and genetic background in nasal carried isolates of Staphylococcus aureus from Asturias, Spain. FEMS Microbiol Lett (2005) 0.90

Detection of staphylococcal superantigenic toxins by a CD69-specific cytofluorimetric assay measuring T-cell activation. J Clin Microbiol (1998) 0.88

Articles by these authors

Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis (2003) 13.83

Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA (2003) 12.04

Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet (2002) 10.26

Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun (2002) 7.34

Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science (2007) 7.06

Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob Agents Chemother (2006) 7.03

Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin Infect Dis (2002) 5.75

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat Genet (2004) 4.93

Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA (2002) 4.48

Global distribution of Panton-Valentine leukocidin--positive methicillin-resistant Staphylococcus aureus, 2006. Emerg Infect Dis (2007) 3.98

Bacterial competition for human nasal cavity colonization: role of Staphylococcal agr alleles. Appl Environ Microbiol (2003) 3.51

Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin. Clin Infect Dis (2007) 3.31

Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila. J Clin Microbiol (2005) 3.21

Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05

Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression. EMBO J (2005) 2.95

Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism. Genes Dev (2007) 2.86

Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils. J Clin Invest (2005) 2.82

Isotope-labeled protein standards: toward absolute quantitative proteomics. Mol Cell Proteomics (2007) 2.63

A single cycle of rituximab for the treatment of severe pemphigus. N Engl J Med (2007) 2.41

A community-wide outbreak of legionnaires disease linked to industrial cooling towers--how far can contaminated aerosols spread? J Infect Dis (2005) 2.38

B-cell depletion immunotherapy in pemphigus: effects on cellular and humoral immune responses. J Invest Dermatol (2008) 2.10

The role of RNAs in the regulation of virulence-gene expression. Curr Opin Microbiol (2006) 2.09

Selection of T cell clones expressing high-affinity public TCRs within Human cytomegalovirus-specific CD8 T cell responses. J Immunol (2005) 2.04

Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey. Clin Infect Dis (2012) 1.97

Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans? J Infect Dis (2010) 1.92

Clinical and environmental distributions of Legionella strains in France are different. J Clin Microbiol (2004) 1.91

Molecular diagnosis of infective endocarditis by PCR amplification and direct sequencing of DNA from valve tissue. J Clin Microbiol (2003) 1.90

Specific real-time polymerase chain reaction places Kingella kingae as the most common cause of osteoarticular infections in young children. Pediatr Infect Dis J (2007) 1.89

Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. Antimicrob Agents Chemother (2007) 1.84

Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species. Genome Res (2008) 1.84

A search for small noncoding RNAs in Staphylococcus aureus reveals a conserved sequence motif for regulation. Nucleic Acids Res (2009) 1.81

High genetic variability of the agr locus in Staphylococcus species. J Bacteriol (2002) 1.78

A novel immunodeficiency associated with hypomorphic RAG1 mutations and CMV infection. J Clin Invest (2005) 1.77

Neutralization of Staphylococcus aureus Panton Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis (2004) 1.76

Outcome and treatment of Bartonella endocarditis. Arch Intern Med (2003) 1.74

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. J Clin Invest (2007) 1.67

The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors. Cell Host Microbe (2013) 1.66

New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance. Int J Antimicrob Agents (2011) 1.66

Pediatric bone and joint infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus. Pediatr Infect Dis J (2007) 1.64

A multicenter evaluation of genotypic methods for the epidemiologic typing of Legionella pneumophila serogroup 1: results of a pan-European study. Clin Microbiol Infect (1999) 1.61

Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections. J Clin Microbiol (2003) 1.61

Virulence determinants in community and hospital meticillin-resistant Staphylococcus aureus. J Hosp Infect (2007) 1.57

Global distribution and evolution of Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus, 1981-2007. J Infect Dis (2010) 1.54

Comparative prevalence of superantigen genes in Staphylococcus aureus isolates causing sepsis with and without septic shock. Clin Infect Dis (2005) 1.53

Interleukin-2 before antiretroviral therapy in patients with HIV infection: a randomized trial (ANRS 119). J Infect Dis (2009) 1.49

Community-acquired methicillin-resistant Staphylococcus aureus isolated in Switzerland contains the Panton-Valentine leukocidin or exfoliative toxin genes. J Clin Microbiol (2004) 1.48

A history of Panton-Valentine leukocidin (PVL)-associated infection protects against death in PVL-associated pneumonia. Vaccine (2011) 1.48

Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS One (2009) 1.48

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS Genet (2010) 1.46

Detection of new methicillin-resistant Staphylococcus aureus clones containing the toxic shock syndrome toxin 1 gene responsible for hospital- and community-acquired infections in France. J Clin Microbiol (2006) 1.46

Contribution of a broad range polymerase chain reaction to the diagnosis of osteoarticular infections caused by Kingella kingae: description of twenty-four recent pediatric diagnoses. Pediatr Infect Dis J (2005) 1.45

Quantitative real-time Legionella PCR for environmental water samples: data interpretation. Appl Environ Microbiol (2006) 1.44