Published in Proc Natl Acad Sci U S A on December 12, 2005
Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73
Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential. J Physiol (2006) 2.68
Connexin 43 hemichannels are permeable to ATP. J Neurosci (2008) 2.46
The gap junction cellular internet: connexin hemichannels enter the signalling limelight. Biochem J (2006) 2.24
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01
Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal (2010) 1.91
Gap junctions. Compr Physiol (2012) 1.59
Developmental regulation of spontaneous activity in the Mammalian cochlea. J Neurosci (2010) 1.54
Molecular properties of P2X receptors. Pflugers Arch (2006) 1.47
Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis. Proc Natl Acad Sci U S A (2007) 1.41
Gap-junction channels dysfunction in deafness and hearing loss. Antioxid Redox Signal (2009) 1.39
Loop gating of connexin hemichannels involves movement of pore-lining residues in the first extracellular loop domain. J Biol Chem (2008) 1.36
Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev (2012) 1.32
Distinct and gradient distributions of connexin26 and connexin30 in the cochlear sensory epithelium of guinea pigs. J Comp Neurol (2006) 1.30
Paracrine signaling through plasma membrane hemichannels. Biochim Biophys Acta (2012) 1.28
Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating. J Gen Physiol (2008) 1.26
Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea. J Comp Neurol (2009) 1.25
Hair cells--beyond the transducer. J Membr Biol (2006) 1.20
Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models. Brain Res (2009) 1.20
Adenine nucleotide changes in the remnant liver: An early signal for regeneration after partial hepatectomy. Hepatology (2008) 1.14
Cellular characterization of Connexin26 and Connnexin30 expression in the cochlear lateral wall. Cell Tissue Res (2008) 1.13
Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. Am J Physiol Cell Physiol (2008) 1.13
Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise. Proc Natl Acad Sci U S A (2013) 1.12
Recent findings and emerging questions in cochlear noise injury. Hear Res (2008) 1.10
Identification and characterization of pannexin expression in the mammalian cochlea. J Comp Neurol (2009) 1.10
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice. Hum Mol Genet (2010) 1.07
ATP-mediated potassium recycling in the cochlear supporting cells. Purinergic Signal (2010) 1.01
Inner ear supporting cells: rethinking the silent majority. Semin Cell Dev Biol (2013) 1.01
Modulation of outer hair cell electromotility by cochlear supporting cells and gap junctions. PLoS One (2009) 1.01
Differentiating connexin hemichannels and pannexin channels in cellular ATP release. FEBS Lett (2014) 1.01
ATP-mediated cell-cell signaling in the organ of Corti: the role of connexin channels. Purinergic Signal (2010) 1.00
Permeation of calcium through purified connexin 26 hemichannels. J Biol Chem (2012) 0.98
Cellular and Deafness Mechanisms Underlying Connexin Mutation-Induced Hearing Loss - A Common Hereditary Deafness. Front Cell Neurosci (2015) 0.97
Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury. Antioxid Redox Signal (2011) 0.95
A novel DFNB1 deletion allele supports the existence of a distant cis-regulatory region that controls GJB2 and GJB6 expression. Clin Genet (2010) 0.93
Purinergic signaling in the inner ear. Hear Res (2007) 0.93
Altered inhibition of Cx26 hemichannels by pH and Zn2+ in the A40V mutation associated with keratitis-ichthyosis-deafness syndrome. J Biol Chem (2014) 0.90
Fibro-vascular coupling in the control of cochlear blood flow. PLoS One (2011) 0.90
Characterization of nonjunctional hemichannels in caterpillar cells. J Insect Sci (2011) 0.90
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice. PLoS One (2011) 0.90
Expression of ecto-ATPase NTPDase2 in human dental pulp. J Dent Res (2011) 0.89
Differential expression of P2Y receptors in the rat cochlea during development. Purinergic Signal (2010) 0.88
P2X antagonists inhibit styryl dye entry into hair cells. Neuroscience (2009) 0.88
ATP activates P2X receptors to mediate gap junctional coupling in the cochlea. Biochem Biophys Res Commun (2012) 0.86
Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing loss. Front Cell Neurosci (2014) 0.86
Adenosine and the auditory system. Curr Neuropharmacol (2009) 0.83
A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing loss. Neurobiol Dis (2010) 0.83
Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications. Cell Commun Signal (2012) 0.82
Hearing loss caused by a P2RX2 mutation identified in a MELAS family with a coexisting mitochondrial 3243AG mutation. Ann Otol Rhinol Laryngol (2015) 0.82
Unmyelinated type II afferent neurons report cochlear damage. Proc Natl Acad Sci U S A (2015) 0.82
Purinergic signaling in cochleovestibular hair cells and afferent neurons. Purinergic Signal (2010) 0.81
Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death. PLoS One (2012) 0.81
Developmental Role of Anoctamin-1/TMEM16A in Ca(2+)-Dependent Volume Change in Supporting Cells of the Mouse Cochlea. Exp Neurobiol (2013) 0.81
Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells. Front Cell Neurosci (2014) 0.81
Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing. Sci Rep (2015) 0.80
Noise-induced alterations in cochlear mechanics, electromotility, and cochlear amplification. Pflugers Arch (2012) 0.80
Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling. Cell Tissue Res (2014) 0.80
Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal (2010) 0.79
Reduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Lossin Mice. Int J Mol Sci (2016) 0.79
Release of ATP from marginal cells in the cochlea of neonatal rats can be induced by changes in extracellular and intracellular ion concentrations. PLoS One (2012) 0.78
Possible role of hemichannels in cancer. Front Physiol (2014) 0.78
Suppression of cell membrane permeability by suramin: involvement of its inhibitory actions on connexin 43 hemichannels. Br J Pharmacol (2014) 0.78
Preferentially regulated expression of connexin 43 in the developing spiral ganglion neurons and afferent terminals in post-natal rat cochlea. Eur J Histochem (2015) 0.77
Maturation of neurotransmission in the developing rat cochlea: immunohistochemical evidence from differential expression of synaptophysin and synaptobrevin 2. Eur J Histochem (2011) 0.77
Recognition and control of the progression of age-related hearing loss. Rejuvenation Res (2013) 0.76
Expression of Vesicular Nucleotide Transporter in Rat Odontoblasts. Acta Histochem Cytochem (2016) 0.76
A role for Innexin2 and Innexin3 proteins from Spodoptera litura in apoptosis. PLoS One (2013) 0.76
The cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma. Mol Neurobiol (2011) 0.76
Differential expression of ryanodine receptor in the developing rat cochlea. Eur J Histochem (2009) 0.75
Connexin43 hemichannels contributes to the disassembly of cell junctions through modulation of intracellular oxidative status. Redox Biol (2016) 0.75
ATP-sensitive K(+) channels (Kir6.1/SUR1) regulate gap junctional coupling in cochlear-supporting cells. Pflugers Arch (2016) 0.75
Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells. PLoS Comput Biol (2016) 0.75
ATP-containing vesicles in stria vascular marginal cell cytoplasms in neonatal rat cochlea are lysosomes. Sci Rep (2016) 0.75
Purinergic signalling during development and ageing. Purinergic Signal (2015) 0.75
Expression and function of pannexins in the inner ear and hearing. BMC Cell Biol (2016) 0.75
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders. Front Mol Neurosci (2017) 0.75
Evoked mechanical responses of isolated cochlear outer hair cells. Science (1985) 9.14
Connexin 26 mutations in hereditary non-syndromic sensorineural deafness. Nature (1997) 6.89
Emerging issues of connexin channels: biophysics fills the gap. Q Rev Biophys (2001) 4.76
A fast motile response in guinea-pig outer hair cells: the cellular basis of the cochlear amplifier. J Physiol (1987) 4.64
The active cochlea. J Neurosci (1992) 4.37
Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels. J Biol Chem (2002) 3.99
Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol (2003) 3.75
Gap junctions: structure and function (Review). Mol Membr Biol (2002) 2.58
Gap junctions in the rat cochlea: immunohistochemical and ultrastructural analysis. Anat Embryol (Berl) (1995) 2.47
New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci (2003) 2.25
Effects of membrane potential on the voltage dependence of motility-related charge in outer hair cells of the guinea-pig. J Physiol (1998) 2.01
Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images. Laryngoscope (1999) 1.99
ATP release through connexin hemichannels in corneal endothelial cells. Invest Ophthalmol Vis Sci (2005) 1.60
Expression of the gap-junction connexins 26 and 30 in the rat cochlea. Cell Tissue Res (1998) 1.58
Connexins are mechanosensitive. Am J Physiol Cell Physiol (2004) 1.46
Connexin channels, connexin mimetic peptides and ATP release. Cell Commun Adhes (2003) 1.45
Expression of the P2X(2) receptor subunit of the ATP-gated ion channel in the cochlea: implications for sound transduction and auditory neurotransmission. J Neurosci (1999) 1.40
Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications. Eur J Neurosci (2005) 1.36
Mechanically induced ATP release from human osteoblastic cells. Biochem Biophys Res Commun (2001) 1.35
Auditory collusion and a coupled couple of outer hair cells. Nature (1999) 1.33
Localization of cholinergic and purinergic receptors on outer hair cells isolated from the guinea-pig cochlea. Proc Biol Sci (1992) 1.16
Voltage gating of gap junctions in cochlear supporting cells: evidence for nonhomotypic channels. J Membr Biol (2000) 1.14
Intercellular communication in the supporting cells of the organ of Corti. Hear Res (1983) 1.08
Effect of membrane tension on gap junctional conductance of supporting cells in Corti's organ. J Gen Physiol (1998) 1.06
Adenosine 5'-triphosphate (ATP) concentrations in the endolymph and perilymph of the guinea-pig cochlea. Hear Res (1995) 1.00
Extracellular adenosine 5'-triphosphate (ATP) in the endolymphatic compartment influences cochlear function. Hear Res (1995) 0.99
Effects of adenosine 5'-triphosphate and related agonists on cochlear function. Hear Res (1994) 0.98
Excitation of fluorescent dyes inactivates the outer hair cell integral membrane motor protein prestin and betrays its lateral mobility. Pflugers Arch (2003) 0.95
P2X receptors in cochlear Deiters' cells. Br J Pharmacol (1998) 0.93
Effects of putative transmitters on afferent cochlear transmission. Ann Otol Rhinol Laryngol (1978) 0.86
Gene expression of P2X-receptors in the developing inner ear of the rat. Neurosci Lett (1999) 0.86
Localization of the P2Y4 receptor in the guinea pig organ of Corti. J Am Acad Audiol (2003) 0.83
Concern Immune protection induced on day 10 following administration of the 2009 A/H1N1 pandemic influenza vaccine. PLoS One (2010) 1.51
Nucleotide variation and haplotype diversity in a 10-kb noncoding region in three continental human populations. Genetics (2006) 1.42
Hierarchical leak detection and localization method in natural gas pipeline monitoring sensor networks. Sensors (Basel) (2011) 1.32
Distinct and gradient distributions of connexin26 and connexin30 in the cochlear sensory epithelium of guinea pigs. J Comp Neurol (2006) 1.30
Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model. Aquat Toxicol (2008) 1.19
Novel deletion in the pre-mRNA splicing gene PRPF31 causes autosomal dominant retinitis pigmentosa in a large Chinese family. Am J Med Genet A (2003) 1.14
How strong is the mutagenicity of recombination in mammals? Mol Biol Evol (2004) 1.13
The role of quantum mechanics in structure-based drug design. Drug Discov Today (2007) 1.09
The change in ocular refractive components after cycloplegia in children. Jpn J Ophthalmol (2002) 0.97
The impact of budgets for gatekeeping physicians on patient satisfaction: evidence from fundholding. J Health Econ (2006) 0.96
Antitumor activity of new liposomal prodrug of mitomycin C in multidrug resistant solid tumor: insights of the mechanism of action. J Drug Target (2007) 0.91
Allometric scaling of pegylated liposomal anticancer drugs. J Pharmacokinet Pharmacodyn (2011) 0.90
Roles of cis- and trans-changes in the regulatory evolution of genes in the gluconeogenic pathway in yeast. Mol Biol Evol (2008) 0.90
Novel regulatory small RNAs in Streptococcus pyogenes. PLoS One (2013) 0.89
Bioavailability and therapeutic efficacy of HER2 scFv-targeted liposomal doxorubicin in a murine model of HER2-overexpressing breast cancer. J Drug Target (2008) 0.88
Community-associated Clostridium difficile infection among older people in Tayside, Scotland, is associated with antibiotic exposure and care home residence: cohort study with nested case-control. J Antimicrob Chemother (2013) 0.88
Cloud computing for detecting high-order genome-wide epistatic interaction via dynamic clustering. BMC Bioinformatics (2014) 0.87
Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor. Arthritis Rheum (2013) 0.87
Epigenetic regulation of TNFA expression in periodontal disease. J Periodontol (2013) 0.87
RNA released from necrotic keratinocytes upregulates intercellular adhesion molecule-1 expression in melanocytes. Arch Dermatol Res (2011) 0.84
Pharmacokinetics, efficacy and toxicity of different pegylated liposomal doxorubicin formulations in preclinical models: is a conventional bioequivalence approach sufficient to ensure therapeutic equivalence of pegylated liposomal doxorubicin products? Cancer Chemother Pharmacol (2010) 0.84
Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus. Clin Exp Med (2013) 0.83
Expression and clinical significance of cathepsin B and stefin A in laryngeal cancer. Oncol Rep (2011) 0.83
Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer (2012) 0.83
The phytoremediation potential of bioenergy crop Ricinus communis for DDTs and cadmium co-contaminated soil. Bioresour Technol (2011) 0.83
Salivary biomarkers in a biofilm overgrowth model. J Periodontol (2014) 0.82
Virulence genes of Porphyromonas gingivalis W83 in chronic periodontitis. Acta Odontol Scand (2009) 0.82
Interaction of a calcium channel blocker with noise in cochlear function in guinea pig. Acta Otolaryngol (2012) 0.82
Accelerated aromatic compounds degradation in aquatic environment by use of interaction between Spirodela polyrrhiza and bacteria in its rhizosphere. J Biosci Bioeng (2006) 0.81
[Expression and significance of Elf-1 and vascular endothelial growth factor in non-small cell lung cancer]. Ai Zheng (2009) 0.80
The sociodemographic characteristics, periodontal health status, and subgingival microbiota of patients with chronic periodontitis and type 2 diabetes mellitus: a case-control study in a Chinese population. J Periodontol (2012) 0.79
Effect of Binghuang ear drop treatment on otitis externa in guinea pigs. Cell Biochem Biophys (2014) 0.79
Folate content and composition of vegetables commonly consumed in China. J Food Sci (2012) 0.79
Natural variation of folate content and composition in spinach (Spinacia oleracea) germplasm. J Agric Food Chem (2011) 0.79
DIME: a novel framework for de novo metagenomic sequence assembly. J Comput Biol (2015) 0.77
Should 'mild primary hyperparathyroidism' be reclassified as 'insidious': is it time to reconsider? Clin Endocrinol (Oxf) (2011) 0.77
The study of corneal topography in myopic and hyperopic children. Yan Ke Xue Bao (2005) 0.77
[A study of frequency of TNF alpha gene with type 2 diabetes mellitus with chronic periodontitis]. Shanghai Kou Qiang Yi Xue (2011) 0.76
Enrichment of bacteria possessing catechol dioxygenase genes in the rhizosphere of Spirodela polyrrhiza: a mechanism of accelerated biodegradation of phenol. Water Res (2009) 0.76
Type I hair cell regeneration induced by Math1 gene transfer following neomycin ototoxicity in rat vestibular sensory epithelium. Acta Otolaryngol (2012) 0.75
Multi-hop localization algorithm based on grid-scanning for wireless sensor networks. Sensors (Basel) (2011) 0.75
Reduced aggregation and cytotoxicity of amyloid peptides by graphene oxide/gold nanocomposites prepared by pulsed laser ablation in water. Small (2014) 0.75
Prophylactic effect of Ca2+ -deficient artificial perilymph perfusion on noise-induced hearing loss. Chin Med J (Engl) (2003) 0.75
Determination of 4-methylpiperaine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride in rats' plasma by online-SPE-HPLC-DAD: application to a pharmacokinetic study. J Sep Sci (2012) 0.75
D-AP5 blocks the increase of intracellular free Ca2+ induced by glutamate in isolated cochlear IHCs. Chin Med J (Engl) (2002) 0.75
[Role of transcription factor ETS-1 and B cell in the pathogenesis of systemic lupus erythematosus]. Zhonghua Yi Xue Za Zhi (2013) 0.75
Clinical and microbiologic effect of nonsurgical periodontal therapy on patients with chronic or aggressive periodontitis. Quintessence Int (2013) 0.75
[A report on a large family with X-linked recessive nonsyndromic hereditary low frequency neuropathic hearing impairment]. Zhonghua Er Bi Yan Hou Ke Za Zhi (2002) 0.75
Clinical Evaluation of Continuous Renal Replacement Therapy in Combination with Ultrasound-Guided Percutaneous Transhepatic Gallbladder Drainage for Acute Severe Biliary Pancreatitis: a Retrospective Study. Kidney Blood Press Res (2017) 0.75
Spermatozoal protein profiles in male infertility with asthenozoospermia. Chin Med J (Engl) (2010) 0.75
[Relationship of porphyromonas gingivalis PG0717 gene with chronic periodontitis]. Hua Xi Kou Qiang Yi Xue Za Zhi (2008) 0.75
Enhancing in vivo Bioavailability in Beagle Dogs of GLM-7 as a Novel Anti-Leukemia Drug through a Self-Emulsifying Drug Delivery System for Oral Delivery. Curr Drug Deliv (2016) 0.75
[Effect of non-surgical periodontal therapy on glycemic control and the level of serum IL-6 in type 2 diabetic patients with chronic periodontitis]. Zhonghua Kou Qiang Yi Xue Za Zhi (2011) 0.75
Abnormal Methylation Status of the GNAS Exon 1A Region in Pseudohypohyperparathyroidism Combined With Turner Syndrome. Am J Med Sci (2015) 0.75
Successful Treatment of Recurrent Pustular Psoriasis of Pregnancy with Secukinumab: A Case Report. Acta Derm Venereol (2020) 0.75
Pygo2 siRNA Inhibit the Growth and Increase Apoptosis of U251 Cell by Suppressing Histone H3K4 Trimethylation. J Mol Neurosci (2015) 0.75
Signalign: An Ontology of DNA as Signal for Comparative Gene Structure Prediction Using Information-Coding-and-Processing Techniques. IEEE Trans Nanobioscience (2016) 0.75
Clinical observation on hearing conditions of centenarians in northern district of China. Acta Otolaryngol (2015) 0.75
Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC-DAD: a cocktail approach. J Chromatogr B Analyt Technol Biomed Life Sci (2013) 0.75
[Effect of ocular accommodation on refractive components in children]. Yan Ke Xue Bao (2002) 0.75
[Fertility and Environmental Impacts of Urban Scattered Human Feces Used as Organic Granular Fertilizer for Leaf Vegetables]. Huan Jing Ke Xue (2015) 0.75
Modification of graphene oxide with amphiphilic double-crystalline block copolymer polyethylene-b-poly(ethylene oxide) with assistance of supercritical CO2 and its further functionalization. J Phys Chem B (2011) 0.75
[The relationship between prevalence of pathogenicity islands genes of Porphyromonas gingivalis and chronic periodontitis]. Shanghai Kou Qiang Yi Xue (2010) 0.75
[Protective effect of indirect activator of calcium pump on noise-induced hearing loss]. Zhonghua Er Bi Yan Hou Ke Za Zhi (2002) 0.75
Low Density Lipoprotein Cholesterol and the Outcome of Acute Ischemic Stroke: Results of a Large Hospital-Based Study. Eur Neurol (2016) 0.75
An autoradiographic study of cochlea and organs of guinea pigs after intraperitoneal injection of 125I-labelled bFGF. Acta Otolaryngol (2010) 0.75
Accelerated degradation of a variety of aromatic compounds by Spirodela polyrrhiza-bacterial associations and contribution of root exudates released from S. polyrrhiza. J Environ Sci (China) (2010) 0.75
Occurrence of 4-tert-butylphenol (4-t-BP) biodegradation in an aquatic sample caused by the presence of Spirodela polyrrhiza and isolation of a 4-t-BP-utilizing bacterium. Biodegradation (2012) 0.75
[Autoradiography observation on cochlea and organs in guinea pigs after intra-abdominal injection of bFGF]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2010) 0.75