Published in J Cell Biochem on May 01, 2006
Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration. J Cell Biol (2007) 1.22
Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach. Cancer Lett (2008) 1.22
A role for the NG2 proteoglycan in glioma progression. Cell Adh Migr (2008) 1.20
CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma. Pigment Cell Melanoma Res (2011) 1.09
Galectins and gliomas. Brain Pathol (2009) 1.01
Proteoglycans and their roles in brain cancer. FEBS J (2013) 0.98
Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B. Cell Res (2014) 0.97
Melanoma biomolecules: independently identified but functionally intertwined. Front Oncol (2013) 0.95
ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol (2014) 0.87
Matrix regulators in neural stem cell functions. Biochim Biophys Acta (2014) 0.79
NG2 cells, a new trail for Alzheimer's disease mechanisms? Acta Neuropathol Commun (2013) 0.78
Functional roles of CSPG4/NG2 in chondrosarcoma. Int J Exp Pathol (2016) 0.75
CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL. Biomedicines (2017) 0.75
A myocardial lineage derives from Tbx18 epicardial cells. Nature (2008) 6.15
Interleukin-17 promotes angiogenesis and tumor growth. Blood (2002) 4.90
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectins: structure, function and therapeutic potential. Expert Rev Mol Med (2008) 2.61
Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest (2003) 2.18
NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin. Mol Biol Cell (2004) 2.14
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol (2006) 2.14
NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J Neurosci (2002) 2.03
Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection. Science (2004) 1.99
Non-stem cell origin for oligodendroglioma. Cancer Cell (2010) 1.95
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proc Natl Acad Sci U S A (2003) 1.94
Early contribution of pericytes to angiogenic sprouting and tube formation. Angiogenesis (2003) 1.89
Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science (2002) 1.87
NG2 proteoglycan expression by pericytes in pathological microvasculature. Microvasc Res (2002) 1.85
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82
Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan. Angiogenesis (2004) 1.62
Galectin-3 induces death of Candida species expressing specific beta-1,2-linked mannans. J Immunol (2006) 1.61
Galectins-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds. J Biol Chem (2002) 1.58
An intimate interplay between precocious, migrating pericytes and endothelial cells governs human fetal brain angiogenesis. Angiogenesis (2007) 1.56
Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectin-like endothelial receptor distinct from E- or P-selectin. Cancer Res (2002) 1.55
Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-δ. Cell Cycle (2011) 1.48
Enhancement of human sperm motility by trophinin binding peptide. J Urol (2008) 1.48
Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan. J Neurosci (2003) 1.45
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol (2008) 1.42
FGF2-dependent neovascularization of subcutaneous Matrigel plugs is initiated by bone marrow-derived pericytes and macrophages. Development (2008) 1.41
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer. Cancer Res (2005) 1.38
Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse. Dev Biol (2010) 1.34
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (2013) 1.33
Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. Proc Natl Acad Sci U S A (2009) 1.32
Macrophage infiltration predicts a poor prognosis for human ewing sarcoma. Am J Pathol (2011) 1.30
Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. J Immunol (2008) 1.29
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Cell mechanics using atomic force microscopy-based single-cell compression. Langmuir (2006) 1.26
Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release. J Biol Chem (2001) 1.25
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol (2004) 1.24
Role of galectin-3 in human pulmonary fibrosis. Allergol Int (2007) 1.24
Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol (2007) 1.23
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration. J Cell Biol (2007) 1.22
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. J Immunol (2004) 1.22
Galectin 3 and its binding protein in rheumatoid arthritis. Arthritis Rheum (2003) 1.20
Regulation of cellular homeostasis by galectins. Glycoconj J (2004) 1.20
Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen. Cancer Immunol Immunother (2010) 1.19
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol Chem (2008) 1.16
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A (2009) 1.16
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
Galectin-3 regulates T-cell functions. Immunol Rev (2009) 1.14
IgE-dependent mast cell activation potentiates airway responses in murine asthma models. J Immunol (2002) 1.13
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol (2008) 1.13
Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol (2006) 1.12
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling. J Biol Chem (2009) 1.12
Galectins in apoptosis. Methods Enzymol (2006) 1.12
Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility. J Biol Chem (2004) 1.11
The immunological potential of galectin-1 and -3. Autoimmun Rev (2008) 1.11
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis. Am J Physiol Renal Physiol (2010) 1.10
A novel phosphatase upregulated in Akp3 knockout mice. Am J Physiol Gastrointest Liver Physiol (2007) 1.09
Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord. J Neuroinflammation (2011) 1.09
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. Diabetes (2005) 1.08
Analysis of axonal regeneration in the central and peripheral nervous systems of the NG2-deficient mouse. BMC Neurosci (2007) 1.07
Allergen-induced airway remodeling is impaired in galectin-3-deficient mice. J Immunol (2010) 1.07
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex. J Biol Chem (2009) 1.06
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. Oncogene (2003) 1.05
Suppression of type 1 diabetes in NOD mice by bifunctional peptide inhibitor: modulation of the immunological synapse formation. Chem Biol Drug Des (2007) 1.04
Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice. Proc Natl Acad Sci U S A (2006) 1.03
Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol (2009) 1.03
Differential responses of spinal axons to transection: influence of the NG2 proteoglycan. Exp Neurol (2005) 1.03
Mast cells and immunological skin diseases. Clin Rev Allergy Immunol (2007) 1.03
NG2 proteoglycan mediates beta1 integrin-independent cell adhesion and spreading on collagen VI. J Cell Biochem (2002) 1.03
NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function. Angiogenesis (2013) 1.03
Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proc Natl Acad Sci U S A (2009) 1.02
Suppression of tumor growth by galectin-7 gene transfer. Cancer Res (2004) 1.02
The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus. PLoS Pathog (2012) 1.01
Essential role of gastric gland mucin in preventing gastric cancer in mice. J Clin Invest (2012) 1.01
LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. PLoS One (2011) 1.01
Differential immunogold localisation of sulphated and unsulphated keratan sulphate proteoglycans in normal and macular dystrophy cornea using sulphation motif-specific antibodies. Histochem Cell Biol (2006) 1.00
The constitutive expression of galectin-3 is downregulated in the intestinal epithelia of Crohn's disease patients, and tumour necrosis factor alpha decreases the level of galectin-3-specific mRNA in HCT-8 cells. Eur J Gastroenterol Hepatol (2002) 0.99
Galectin-12 is required for adipogenic signaling and adipocyte differentiation. J Biol Chem (2004) 0.99
B cell depletion therapy exacerbates murine primary biliary cirrhosis. Hepatology (2010) 0.99
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol (2007) 0.99
Adventitial pericyte progenitor/mesenchymal stem cells participate in the restenotic response to arterial injury. J Vasc Res (2012) 0.99
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth. Cancer Res (2006) 0.98
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas. Am J Pathol (2004) 0.98
Association of a macrophage galactoside-binding protein with Mycobacterium-containing phagosomes. Cell Microbiol (2002) 0.97
NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse. J Histochem Cytochem (2007) 0.97
Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects. J Biol Chem (2010) 0.97
Lymphatic/Blood endothelial cell connections at the capillary level in adult rat mesentery. Anat Rec (Hoboken) (2010) 0.95
Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis. Biochem J (2007) 0.95
Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications. Mod Pathol (2002) 0.95
Expression of NG2 proteoglycan during endochondral and intramembranous ossification. Dev Dyn (2003) 0.95
Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol (2013) 0.95
Rosacea: skin innate immunity gone awry? Nat Med (2007) 0.95
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Exp Diabetes Res (2007) 0.94