Published in J Am Chem Soc on December 28, 2005
Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Chem Res Toxicol (2009) 1.11
Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine. Chem Res Toxicol (2008) 1.00
Chemical discrimination between dC and 5MedC via their hydroxylamine adducts. Nucleic Acids Res (2010) 0.91
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. J Am Chem Soc (2006) 0.90
Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions. Nat Chem Biol (2013) 0.89
Molecular mechanics parameters for the FapydG DNA lesion. J Comput Chem (2008) 0.87
Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules. J Clin Biochem Nutr (2014) 0.86
Solution structure of duplex DNA containing a β-carba-Fapy-dG lesion. Chem Res Toxicol (2012) 0.85
The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA. Nucleic Acids Res (2012) 0.85
Novel post-synthetic generation, isomeric resolution, and characterization of Fapy-dG within oligodeoxynucleotides: differential anomeric impacts on DNA duplex properties. Nucleic Acids Res (2011) 0.83
5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases. Nucleic Acids Res (2011) 0.81
Chemical syntheses of oligodeoxyribonucleotides containing spore photoproduct. J Org Chem (2013) 0.81
Destabilization of DNA duplexes by oxidative damage at guanine: implications for lesion recognition and repair. J R Soc Interface (2008) 0.80
DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Bioorg Med Chem (2008) 0.79
Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and N-(carboxymethyl)lysine in human epidermis. J Clin Biochem Nutr (2011) 0.78
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. J Am Chem Soc (2015) 0.78
Synthesis of N2-alkyl-8-oxo-7,8-dihydro-2'-deoxyguanosine derivatives and effects of these modifications on RNA duplex stability. J Org Chem (2010) 0.77
Chemical Biology of N(5)-Substituted Formamidopyrimidine DNA Adducts. Chem Res Toxicol (2016) 0.75
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One (2010) 6.38
The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem Int Ed Engl (2011) 4.39
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Cell (2013) 4.16
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Quantification of the sixth DNA base hydroxymethylcytosine in the brain. Angew Chem Int Ed Engl (2010) 3.50
Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature (2004) 2.68
Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair. Science (2004) 2.51
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. EMBO J (2009) 2.37
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet (2013) 2.24
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell (2013) 2.22
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol (2007) 2.20
Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Mol Cell (2012) 1.96
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta. Science (2007) 1.94
Click chemistry as a reliable method for the high-density postsynthetic functionalization of alkyne-modified DNA. Org Lett (2006) 1.85
Identification of target genes of the p16INK4A-pRB-E2F pathway. J Biol Chem (2003) 1.83
19p13.1 is a triple-negative-specific breast cancer susceptibility locus. Cancer Res (2012) 1.81
CPD damage recognition by transcribing RNA polymerase II. Science (2007) 1.80
Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites. Hum Mol Genet (2013) 1.77
Crystal structure and mechanism of a DNA (6-4) photolyase. Angew Chem Int Ed Engl (2008) 1.76
Thymine dimerization in DNA is an ultrafast photoreaction. Science (2007) 1.68
Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study. Am J Clin Nutr (2013) 1.62
5-Hydroxymethylcytosine, the sixth base of the genome. Angew Chem Int Ed Engl (2011) 1.56
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. Hum Mol Genet (2011) 1.56
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors. PLoS Genet (2013) 1.56
DEK Expression is controlled by E2F and deregulated in diverse tumor types. Cell Cycle (2006) 1.55
The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling. EMBO Rep (2011) 1.47
DNA--metal base pairs. Angew Chem Int Ed Engl (2007) 1.46
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet (2013) 1.39
Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing. Angew Chem Int Ed Engl (2012) 1.34
Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase. J Biol Chem (2004) 1.33
Mechanism of transcriptional stalling at cisplatin-damaged DNA. Nat Struct Mol Biol (2007) 1.32
Copper-free "click" modification of DNA via nitrile oxide-norbornene 1,3-dipolar cycloaddition. Org Lett (2009) 1.31
Postsynthetic DNA modification through the copper-catalyzed azide-alkyne cycloaddition reaction. Angew Chem Int Ed Engl (2008) 1.30
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors. Int J Cancer (2012) 1.30
PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. PLoS Genet (2011) 1.27
11q13 is a susceptibility locus for hormone receptor positive breast cancer. Hum Mutat (2012) 1.26
Directed DNA metallization. J Am Chem Soc (2006) 1.26
A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction. Angew Chem Int Ed Engl (2012) 1.25
Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome. Proc Natl Acad Sci U S A (2008) 1.24
Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer. Cancer Epidemiol Biomarkers Prev (2011) 1.23
Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals. Gastroenterology (2010) 1.18
DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity. Nucleic Acids Res (2011) 1.17
Parallel isotope-based quantification of modified tRNA nucleosides. Angew Chem Int Ed Engl (2009) 1.14
Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS One (2012) 1.13
Characterization of a new thermophilic spore photoproduct lyase from Geobacillus stearothermophilus (SplG) with defined lesion containing DNA substrates. J Biol Chem (2006) 1.13
The redesigned follitropin α pen injector for infertility treatment. Expert Opin Drug Deliv (2011) 1.11
Development and evaluation of a modification of the Fried frailty criteria using population-independent cutpoints. J Am Geriatr Soc (2012) 1.11
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia. Oncogene (2005) 1.09
Click-click-click: single to triple modification of DNA. Angew Chem Int Ed Engl (2008) 1.09
Efficient synthesis of 5-hydroxymethylcytosine containing DNA. Org Lett (2010) 1.07
Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair. Nat Chem (2011) 1.07
Synthesis of highly modified DNA by a combination of PCR with alkyne-bearing triphosphates and click chemistry. Chemistry (2007) 1.06
Transfer printing of DNA by "click" chemistry. Chembiochem (2007) 1.06
Steric and electronic effects in cyclic alkoxyamines--synthesis and applications as regulators for controlled/living radical polymerization. Chemistry (2004) 1.05
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA. PLoS Biol (2011) 1.05
Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance. Am J Med Genet B Neuropsychiatr Genet (2010) 1.05
Synthesis and stereochemical assignment of DNA spore photoproduct analogues. Chemistry (2006) 1.04
Structural biology of DNA photolyases and cryptochromes. Curr Opin Struct Biol (2009) 1.04
Improved synthesis and mutagenicity of oligonucleotides containing 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine. Chemistry (2011) 1.03
First application of Cc-corrected imaging for high-resolution and energy-filtered TEM. J Electron Microsc (Tokyo) (2009) 1.03
8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1. Nucleic Acids Res (2011) 1.03
Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNA. EMBO J (2011) 1.02
Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase. Hepatology (2009) 1.02
Frailty prevalence and 10-year survival in community-dwelling older adults: results from the ESTHER cohort study. Eur J Epidemiol (2014) 1.01
Synthesis and properties of DNA containing a spore photoproduct analog. Chem Commun (Camb) (2008) 1.00
Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. Int J Cancer (2014) 0.99
Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system. Chem Commun (Camb) (2012) 0.99
Programmable self-assembly of metal ions inside artificial DNA duplexes. Nat Nanotechnol (2006) 0.99
Serum 25-hydroxyvitamin d and cancer risk in older adults: results from a large German prospective cohort study. Cancer Epidemiol Biomarkers Prev (2013) 0.99
Natural and non-natural antenna chromophores in the DNA photolyase from Thermus thermophilus. Chembiochem (2006) 0.99
Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res (2012) 0.99
Temporal predictors of health-related quality of life in elderly people with diabetes: results of a German cohort study. PLoS One (2012) 0.98
Using rate advancement periods for communicating the benefits of quitting smoking to older smokers. Tob Control (2012) 0.98
The spore photoproduct lyase repairs the 5S- and not the 5R-configured spore photoproduct DNA lesion. Chem Commun (Camb) (2006) 0.97
Systems-based analysis of modified tRNA bases. Angew Chem Int Ed Engl (2011) 0.97
Mechanism of replication blocking and bypass of Y-family polymerase {eta} by bulky acetylaminofluorene DNA adducts. Proc Natl Acad Sci U S A (2010) 0.96
Crystal structure of the T(6-4)C lesion in complex with a (6-4) DNA photolyase and repair of UV-induced (6-4) and Dewar photolesions. Chemistry (2009) 0.96
Columba: an integrated database of proteins, structures, and annotations. BMC Bioinformatics (2005) 0.95
9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev (2012) 0.95
A programmable DNA-based molecular valve for colloidal mesoporous silica. Angew Chem Int Ed Engl (2010) 0.95
Synthesis, stability, and conformation of the formamidopyrimidine G DNA lesion. Chemistry (2002) 0.95
GenePicker: replicate analysis of Affymetrix gene expression microarrays. Bioinformatics (2004) 0.95
The two main DNA lesions 8-Oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing properties. Angew Chem Int Ed Engl (2003) 0.95
Proinflammatory cytokines, adiponectin, and increased risk of primary cardiovascular events in diabetic patients with or without renal dysfunction: results from the ESTHER study. Diabetes Care (2013) 0.95
Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine. J Am Chem Soc (2013) 0.95
Vitamin D and cognitive functioning in the elderly population in Germany. Exp Gerontol (2011) 0.93
Fluorescent DNA nanotags featuring covalently attached intercalating dyes: synthesis, antibody conjugation, and intracellular imaging. Bioconjug Chem (2011) 0.93
The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes. Proc Natl Acad Sci U S A (2009) 0.92
Chemical discrimination between dC and 5MedC via their hydroxylamine adducts. Nucleic Acids Res (2010) 0.91
Controlled stacking of 10 transition-metal ions inside a DNA duplex. Angew Chem Int Ed Engl (2007) 0.91
Thermal magnetic field noise limits resolution in transmission electron microscopy. Phys Rev Lett (2013) 0.91