Published in Infect Immun on January 01, 2006
Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol (2007) 2.32
Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids. PLoS One (2012) 1.28
Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease. Infect Immun (2007) 1.17
Borrelia burgdorferi adhesins identified using in vivo phage display. Mol Microbiol (2007) 1.17
The role of Borrelia burgdorferi outer surface proteins. FEMS Immunol Med Microbiol (2012) 1.16
Temporal expression analysis of the Borrelia burgdorferi paralogous gene family 54 genes BBA64, BBA65, and BBA66 during persistent infection in mice. Infect Immun (2007) 1.07
CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect Immun (2009) 1.07
The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission. Proc Natl Acad Sci U S A (2010) 1.07
CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi. Infect Immun (2010) 1.07
Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity. PLoS One (2008) 1.05
Role of the surface lipoprotein BBA07 in the enzootic cycle of Borrelia burgdorferi. Infect Immun (2010) 1.03
Characterization of unique regions of Borrelia burgdorferi surface-located membrane protein 1. Infect Immun (2010) 1.00
Borrelia burgdorferi BBA74, a periplasmic protein associated with the outer membrane, lacks porin-like properties. J Bacteriol (2006) 0.95
Overexpression of CsrA (BB0184) alters the morphology and antigen profiles of Borrelia burgdorferi. Infect Immun (2009) 0.94
A surface enolase participates in Borrelia burgdorferi-plasminogen interaction and contributes to pathogen survival within feeding ticks. Infect Immun (2011) 0.93
Borrelia burgdorferi surface-localized proteins expressed during persistent murine infection are conserved among diverse Borrelia spp. Infect Immun (2008) 0.93
Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation. PLoS One (2011) 0.92
Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi. Infect Immun (2009) 0.90
Borrelia burgdorferi BBA52 is a potential target for transmission blocking Lyme disease vaccine. Vaccine (2011) 0.89
Binding of human complement regulators FHL-1 and factor H to CRASP-1 orthologs of Borrelia burgdorferi. Wien Klin Wochenschr (2006) 0.89
Specificity and role of the Borrelia burgdorferi CtpA protease in outer membrane protein processing. J Bacteriol (2011) 0.86
Fast, adaptive evolution at a bacterial host-resistance locus: the PFam54 gene array in Borrelia burgdorferi. Gene (2009) 0.86
Deletion of BBA64, BBA65, and BBA66 loci does not alter the infectivity of Borrelia burgdorferi in the murine model of Lyme disease. Infect Immun (2008) 0.86
BBK07, a dominant in vivo antigen of Borrelia burgdorferi, is a potential marker for serodiagnosis of Lyme disease. Clin Vaccine Immunol (2009) 0.86
Structural modeling and physicochemical characterization provide evidence that P66 forms a β-barrel in the Borrelia burgdorferi outer membrane. J Bacteriol (2013) 0.85
A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaete Treponema denticola. Mol Microbiol (2013) 0.81
BB0324 and BB0028 are constituents of the Borrelia burgdorferi β-barrel assembly machine (BAM) complex. BMC Microbiol (2012) 0.81
A Borrelia burgdorferi Surface-Exposed Transmembrane Protein Lacking Detectable Immune Responses Supports Pathogen Persistence and Constitutes a Vaccine Target. J Infect Dis (2016) 0.81
Borrelia burgdorferi bba66 gene inactivation results in attenuated mouse infection by tick transmission. Infect Immun (2013) 0.80
BB0172, a Borrelia burgdorferi outer membrane protein that binds integrin α3β1. J Bacteriol (2013) 0.78
Borrelia burgdorferi elongation factor EF-Tu is an immunogenic protein during Lyme borreliosis. Emerg Microbes Infect (2015) 0.78
Raft-like membrane domains in pathogenic microorganisms. Curr Top Membr (2015) 0.78
BB0238, a presumed tetratricopeptide repeat-containing protein, is required during Borrelia burgdorferi mammalian infection. Infect Immun (2014) 0.77
Evaluation of Selected Borrelia burgdorferi lp54 Plasmid-Encoded Gene Products Expressed during Mammalian Infection as Antigens To Improve Serodiagnostic Testing for Early Lyme Disease. Clin Vaccine Immunol (2015) 0.77
Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes. BMC Microbiol (2016) 0.77
The Borrelia afzelii outer membrane protein BAPKO_0422 binds human factor-H and is predicted to form a membrane-spanning β-barrel. Biosci Rep (2015) 0.76
Evaluation of the Borrelia burgdorferi BBA64 protein as a protective immunogen in mice. Clin Vaccine Immunol (2014) 0.76
Hypothetical Protein BB0569 Is Essential for Chemotaxis of the Lyme Disease Spirochete Borrelia burgdorferi. J Bacteriol (2015) 0.76
Characterization of the β-barrel assembly machine accessory lipoproteins from Borrelia burgdorferi. BMC Microbiol (2015) 0.76
Antibody response to Lyme disease spirochetes in the context of VlsE-mediated immune evasion. Infect Immun (2016) 0.75
Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias Toward the Bacterial Surface. J Bacteriol (2017) 0.75
Outer membrane proteins BB0405 and BB0406 are immunogenic but only BB0405 is required for Borrelia burgdorferi infection. Infect Immun (2016) 0.75
A simple method for displaying the hydropathic character of a protein. J Mol Biol (1982) 150.65
Improved prediction of signal peptides: SignalP 3.0. J Mol Biol (2004) 48.40
Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. Anal Biochem (1981) 29.21
Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med (1985) 20.49
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature (1997) 19.08
The complete general secretory pathway in gram-negative bacteria. Microbiol Rev (1993) 16.84
Lyme disease. N Engl J Med (1989) 14.06
Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc Natl Acad Sci U S A (1995) 9.93
Prediction of lipoprotein signal peptides in Gram-negative bacteria. Protein Sci (2003) 6.85
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals. Proc Natl Acad Sci U S A (2004) 3.84
Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe. Annu Rev Entomol (1991) 3.75
Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc Natl Acad Sci U S A (2001) 3.65
Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background. Infect Immun (2002) 3.65
A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest (1998) 3.41
Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice. Cell (1997) 3.25
Profiling of temperature-induced changes in Borrelia burgdorferi gene expression by using whole genome arrays. Infect Immun (2003) 3.19
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol (1995) 2.92
Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect Immun (2003) 2.79
A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: evidence for expression only during infection. Infect Immun (1994) 2.74
Passive immunization of hamsters against experimental infection with the Lyme disease spirochete. Infect Immun (1986) 2.55
Molecular adaptation of Borrelia burgdorferi in the murine host. J Exp Med (2002) 2.49
Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity. Immunity (1997) 2.38
In vitro inhibition of Borrelia burgdorferi growth by antibodies. J Infect Dis (1993) 2.31
Spirochaetal lipoproteins and pathogenesis. Microbiology (2000) 2.30
Identification of loci critical for replication and compatibility of a Borrelia burgdorferi cp32 plasmid and use of a cp32-based shuttle vector for the expression of fluorescent reporters in the lyme disease spirochaete. Mol Microbiol (2002) 2.28
Temporal pattern of Borrelia burgdorferi p21 expression in ticks and the mammalian host. J Clin Invest (1997) 2.13
Arthropod- and host-specific gene expression by Borrelia burgdorferi. J Clin Invest (1997) 2.05
Role of immunoglobulin G in killing of Borrelia burgdorferi by the classical complement pathway. Infect Immun (1988) 1.97
Active immunization of hamsters against experimental infection with Borrelia burgdorferi. Infect Immun (1986) 1.94
Surveillance for Lyme disease--United States, 1992-1998. MMWR CDC Surveill Summ (2000) 1.91
Limited surface exposure of Borrelia burgdorferi outer surface lipoproteins. Proc Natl Acad Sci U S A (1996) 1.90
Decreased electroporation efficiency in Borrelia burgdorferi containing linear plasmids lp25 and lp56: impact on transformation of infectious B. burgdorferi. Infect Immun (2002) 1.83
Characterization of a candidate Borrelia burgdorferi beta3-chain integrin ligand identified using a phage display library. Mol Microbiol (1999) 1.82
Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signals. Infect Immun (2001) 1.73
Isolation of integral membrane proteins by phase partitioning with Triton X-114. Methods Enzymol (1994) 1.70
bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector. Proc Natl Acad Sci U S A (2005) 1.66
Lyme disease: a growing threat to urban populations. Proc Natl Acad Sci U S A (1994) 1.66
Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun (2002) 1.65
Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy. J Bacteriol (1994) 1.61
Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection. Infect Immun (1997) 1.57
Lyme disease--United States, 2001-2002. MMWR Morb Mortal Wkly Rep (2004) 1.55
Immune evasion by tickborne and host-adapted Borrelia burgdorferi. J Infect Dis (1998) 1.52
Lyme disease. Adv Intern Med (1995) 1.49
Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity. Infect Immun (1993) 1.47
Lyme disease: a review of aspects of its immunology and immunopathogenesis. Annu Rev Immunol (1997) 1.45
OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human lyme disease patients. J Clin Microbiol (2002) 1.41
Complement-mediated killing of the Lyme disease spirochete Borrelia burgdorferi. Role of antibody in formation of an effective membrane attack complex. J Immunol (1991) 1.40
Borrelia burgdorferi transcriptome in the central nervous system of non-human primates. Proc Natl Acad Sci U S A (2003) 1.26
DNA microarray assessment of putative Borrelia burgdorferi lipoprotein genes. Infect Immun (2002) 1.25
Molecular characterization, genomic arrangement, and expression of bmpD, a new member of the bmp class of genes encoding membrane proteins of Borrelia burgdorferi. Infect Immun (1996) 1.25
Delineation of Borrelia burgdorferi p66 sequences required for integrin alpha(IIb)beta(3) recognition. Infect Immun (2001) 1.23
The versatile roles of antibodies in Borrelia infections. Nat Rev Microbiol (2005) 1.21
Fibroblasts protect the Lyme disease spirochete, Borrelia burgdorferi, from ceftriaxone in vitro. J Infect Dis (1992) 1.21
Modification of bacterial lipoproteins. Methods Enzymol (1995) 1.21
Vaccination of hamsters against experimental infection with Borrelia burgdorferi. Zentralbl Bakteriol Mikrobiol Hyg A (1986) 1.17
Quantitative analysis of Borrelia burgdorferi gene expression in naturally (tick) infected mouse strains. Med Microbiol Immunol (2005) 0.98
Localization of Borrelia burgdorferi in murine Lyme borreliosis by electron microscopy. Am J Trop Med Hyg (1995) 0.97
Artificial-infection protocols allow immunodetection of novel Borrelia burgdorferi antigens suitable as vaccine candidates against Lyme disease. Eur J Immunol (2003) 0.95
Borrelia burgdorferi and its tropisms for adhesion molecules in the joint. Curr Opin Rheumatol (2002) 0.86
Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background. Infect Immun (2002) 3.65
Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect Immun (2003) 2.79
Staphylococcus aureus serves as an iron source for Pseudomonas aeruginosa during in vivo coculture. J Bacteriol (2005) 2.04
Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun (2002) 1.65
Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi. J Immunol (2005) 1.42
OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human lyme disease patients. J Clin Microbiol (2002) 1.41
Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H. J Immunol (2004) 1.20
The role of Borrelia burgdorferi outer surface proteins. FEMS Immunol Med Microbiol (2012) 1.16
Growth, development, and gene expression in a persistent Streptococcus gordonii biofilm. Infect Immun (2003) 1.09
CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect Immun (2009) 1.07
The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun (2011) 1.07
Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity. PLoS One (2008) 1.05
Borrelia burgdorferi locus BB0795 encodes a BamA orthologue required for growth and efficient localization of outer membrane proteins. Mol Microbiol (2009) 1.04
Characterization of unique regions of Borrelia burgdorferi surface-located membrane protein 1. Infect Immun (2010) 1.00
Expression of complement factor H binding immunoevasion proteins in Borrelia garinii isolated from patients with neuroborreliosis. Eur J Immunol (2005) 1.00
Whole-genome DNA array analysis of the response of Borrelia burgdorferi to a bactericidal monoclonal antibody. Infect Immun (2004) 0.90
The OspE-related proteins inhibit complement deposition and enhance serum resistance of Borrelia burgdorferi, the lyme disease spirochete. Infect Immun (2011) 0.89
Structural modeling and physicochemical characterization provide evidence that P66 forms a β-barrel in the Borrelia burgdorferi outer membrane. J Bacteriol (2013) 0.85
BB0324 and BB0028 are constituents of the Borrelia burgdorferi β-barrel assembly machine (BAM) complex. BMC Microbiol (2012) 0.81
Assessment of Translational and Interdisciplinary Clinical Research at an Oklahoma Health Sciences Center. J Okla State Med Assoc (2015) 0.75