Published in Proc Natl Acad Sci U S A on October 23, 2001
Diagnosis of lyme borreliosis. Clin Microbiol Rev (2005) 4.48
DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc Natl Acad Sci U S A (2002) 3.82
Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes. Nat Rev Microbiol (2012) 3.52
OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest (2004) 3.38
Profiling of temperature-induced changes in Borrelia burgdorferi gene expression by using whole genome arrays. Infect Immun (2003) 3.19
Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med (2004) 3.02
Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect Immun (2003) 2.79
Domain architectures of sigma54-dependent transcriptional activators. J Bacteriol (2003) 2.57
Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection. Infect Immun (2006) 2.54
Molecular adaptation of Borrelia burgdorferi in the murine host. J Exp Med (2002) 2.49
Borrelia burgdorferi sigma54 is required for mammalian infection and vector transmission but not for tick colonization. Proc Natl Acad Sci U S A (2005) 2.41
Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array. Infect Immun (2004) 2.35
Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol (2007) 2.32
The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc Natl Acad Sci U S A (2003) 2.31
An immune evasion mechanism for spirochetal persistence in Lyme borreliosis. J Exp Med (2002) 2.25
Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences. Mol Microbiol (2008) 2.23
aadA confers streptomycin resistance in Borrelia burgdorferi. J Bacteriol (2003) 2.22
BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype. Infect Immun (2004) 2.08
RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants. Infect Immun (2004) 1.94
Decreased electroporation efficiency in Borrelia burgdorferi containing linear plasmids lp25 and lp56: impact on transformation of infectious B. burgdorferi. Infect Immun (2002) 1.83
Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses. Infect Immun (2004) 1.82
Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks. J Clin Invest (2009) 1.78
bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector. Proc Natl Acad Sci U S A (2005) 1.66
Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi. Infect Immun (2008) 1.63
Retracted Localization of BmpA on the exposed outer membrane of Borrelia burgdorferi by monospecific anti-recombinant BmpA rabbit antibodies. Infect Immun (2004) 1.56
Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response. Infect Immun (2005) 1.55
Insights into the complex regulation of rpoS in Borrelia burgdorferi. Mol Microbiol (2007) 1.54
The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation. PLoS Pathog (2015) 1.54
Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions. Mol Microbiol (2009) 1.45
Analysis of the ospC regulatory element controlled by the RpoN-RpoS regulatory pathway in Borrelia burgdorferi. J Bacteriol (2005) 1.44
Antigenic composition of Borrelia burgdorferi during infection of SCID mice. Infect Immun (2003) 1.43
BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Mol Microbiol (2009) 1.42
Alternate sigma factor RpoS is required for the in vivo-specific repression of Borrelia burgdorferi plasmid lp54-borne ospA and lp6.6 genes. J Bacteriol (2005) 1.40
The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete. Mol Microbiol (2009) 1.37
Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection. Infect Immun (2008) 1.36
Biology of infection with Borrelia burgdorferi. Infect Dis Clin North Am (2008) 1.35
Analysis of promoter elements involved in the transcriptional initiation of RpoS-dependent Borrelia burgdorferi genes. J Bacteriol (2004) 1.35
Role of RpoS in virulence of pathogens. Infect Immun (2009) 1.35
Evidence that RpoS (sigmaS) in Borrelia burgdorferi is controlled directly by RpoN (sigma54/sigmaN). J Bacteriol (2006) 1.34
Borrelia burgdorferi alters its gene expression and antigenic profile in response to CO2 levels. J Bacteriol (2006) 1.32
Expression of a luxS gene is not required for Borrelia burgdorferi infection of mice via needle inoculation. Infect Immun (2003) 1.32
Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi. PLoS Pathog (2010) 1.29
Identification of Borrelia burgdorferi outer surface proteins. Infect Immun (2006) 1.23
BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism. PLoS Pathog (2011) 1.22
Effects of vlsE complementation on the infectivity of Borrelia burgdorferi lacking the linear plasmid lp28-1. Infect Immun (2004) 1.22
Regulation of expression of the paralogous Mlp family in Borrelia burgdorferi. Infect Immun (2003) 1.21
Borrelia burgdorferi RevA antigen binds host fibronectin. Infect Immun (2009) 1.21
Dissolved oxygen levels alter gene expression and antigen profiles in Borrelia burgdorferi. Infect Immun (2004) 1.19
Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle. Infect Immun (2007) 1.18
Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease. Infect Immun (2007) 1.17
LuxS-mediated quorum sensing in Borrelia burgdorferi, the lyme disease spirochete. Infect Immun (2002) 1.17
Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. PLoS Negl Trop Dis (2010) 1.16
Adaptation of a luciferase gene reporter and lac expression system to Borrelia burgdorferi. Appl Environ Microbiol (2007) 1.16
The role of Borrelia burgdorferi outer surface proteins. FEMS Immunol Med Microbiol (2012) 1.16
BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts. J Infect Dis (2010) 1.16
Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals. J Bacteriol (2009) 1.14
Environmental regulation and differential production of members of the Bdr protein family of Borrelia burgdorferi. Infect Immun (2002) 1.13
Identification and function of the RNA chaperone Hfq in the Lyme disease spirochete Borrelia burgdorferi. Mol Microbiol (2010) 1.12
Borrelia burgdorferi and tick proteins supporting pathogen persistence in the vector. Future Microbiol (2013) 1.12
A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi. Proc Natl Acad Sci U S A (2009) 1.11
The decrease in FlaA observed in a flaB mutant of Borrelia burgdorferi occurs posttranscriptionally. J Bacteriol (2004) 1.10
CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi. Infect Immun (2010) 1.07
The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun (2011) 1.07
Characterization of a conditional bosR mutant in Borrelia burgdorferi. Infect Immun (2009) 1.06
Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle. PLoS Pathog (2011) 1.06
Rrp2, a sigma54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner. J Bacteriol (2009) 1.06
Inactivation of bb0184, which encodes carbon storage regulator A, represses the infectivity of Borrelia burgdorferi. Infect Immun (2010) 1.05
Characterization of multiprotein complexes of the Borrelia burgdorferi outer membrane vesicles. J Proteome Res (2011) 1.04
Regulators of expression of the oligopeptide permease A proteins of Borrelia burgdorferi. J Bacteriol (2007) 1.04
Role of the surface lipoprotein BBA07 in the enzootic cycle of Borrelia burgdorferi. Infect Immun (2010) 1.03
Evolving models of Lyme disease spirochete gene regulation. Wien Klin Wochenschr (2006) 1.02
Carbon storage regulator A (CsrA(Bb)) is a repressor of Borrelia burgdorferi flagellin protein FlaB. Mol Microbiol (2011) 1.02
Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation. Mol Microbiol (2014) 1.00
Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi. Mol Microbiol (2013) 1.00
Who is the BosR around here anyway? Mol Microbiol (2009) 1.00
Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi. PLoS One (2012) 0.98
Modulation of Borrelia burgdorferi stringent response and gene expression during extracellular growth with tick cells. Infect Immun (2002) 0.98
Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi. BMC Microbiol (2012) 0.97
Borrelia burgdorferi rel is responsible for generation of guanosine-3'-diphosphate-5'-triphosphate and growth control. Infect Immun (2005) 0.97
Expression of the bmpB gene of Borrelia burgdorferi is modulated by two distinct transcription termination events. J Bacteriol (2005) 0.96
Changes in bacterial growth rate govern expression of the Borrelia burgdorferi OspC and Erp infection-associated surface proteins. J Bacteriol (2012) 0.95
Overexpression of CsrA (BB0184) alters the morphology and antigen profiles of Borrelia burgdorferi. Infect Immun (2009) 0.94
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. PLoS Negl Trop Dis (2016) 0.94
Borrelia burgdorferi surface-localized proteins expressed during persistent murine infection are conserved among diverse Borrelia spp. Infect Immun (2008) 0.93
Differential expression of a putative CarD-like transcriptional regulator, LtpA, in Borrelia burgdorferi. Infect Immun (2008) 0.93
Abrogation of ospAB constitutively activates the Rrp2-RpoN-RpoS pathway (sigmaN-sigmaS cascade) in Borrelia burgdorferi. Mol Microbiol (2008) 0.93
bdrF2 of Lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection. J Bacteriol (2005) 0.92
Inactivation of alternative sigma factor 54 (RpoN) leads to increased acid resistance, and alters locus of enterocyte effacement (LEE) expression in Escherichia coli O157 : H7. Microbiology (2009) 0.92
Verification and dissection of the ospC operator by using flaB promoter as a reporter in Borrelia burgdorferi. Microb Pathog (2008) 0.91
Reciprocal expression of ospA and ospC in single cells of Borrelia burgdorferi. J Bacteriol (2008) 0.91
Study of the response regulator Rrp1 reveals its regulatory role in chitobiose utilization and virulence of Borrelia burgdorferi. Infect Immun (2013) 0.91
EbfC (YbaB) is a new type of bacterial nucleoid-associated protein and a global regulator of gene expression in the Lyme disease spirochete. J Bacteriol (2012) 0.91
HrpA, a DEAH-box RNA helicase, is involved in global gene regulation in the Lyme disease spirochete. PLoS One (2011) 0.90
Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi. Infect Immun (2009) 0.90
Whole-genome DNA array analysis of the response of Borrelia burgdorferi to a bactericidal monoclonal antibody. Infect Immun (2004) 0.90
Molecular signaling mechanisms of the periopathogen, Treponema denticola. J Dent Res (2011) 0.90
Sigma cascades in prokaryotic regulatory networks. Proc Natl Acad Sci U S A (2005) 0.89
Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin. Infect Immun (2010) 0.89
Crosstalk regulation among group 2-sigma factors in Synechocystis PCC6803. BMC Microbiol (2005) 0.89
Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi. J Bacteriol (2007) 0.89
Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature (1997) 19.08
Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc Natl Acad Sci U S A (1995) 9.93
Lyme borreliosis in selected strains and ages of laboratory mice. J Infect Dis (1990) 5.95
Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J Exp Med (1996) 5.46
Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice. J Clin Microbiol (2000) 4.71
Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun (1995) 4.68
Molecular Koch's postulates applied to microbial pathogenicity. Rev Infect Dis (1988) 4.51
Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi. Infect Immun (1993) 4.16
An M protein with a single C repeat prevents phagocytosis of Streptococcus pyogenes: use of a temperature-sensitive shuttle vector to deliver homologous sequences to the chromosome of S. pyogenes. Mol Microbiol (1993) 3.76
The bacterial enhancer-dependent sigma(54) (sigma(N)) transcription factor. J Bacteriol (2000) 3.63
Electrotransformation of the spirochete Borrelia burgdorferi. Methods Mol Biol (1995) 3.50
The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid. Infect Immun (1993) 3.50
A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest (1998) 3.41
Transcriptional analyses and mapping of the ospC gene in Lyme disease spirochetes. J Bacteriol (1993) 3.35
Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks. Proc Natl Acad Sci U S A (2001) 3.28
Back to log phase: sigma S as a global regulator in the osmotic control of gene expression in Escherichia coli. Mol Microbiol (1996) 3.14
Eubacterial sigma-factors. FEMS Microbiol Rev (1998) 3.13
Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am J Trop Med Hyg (1995) 3.04
Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol (2000) 3.00
Isolation of a circular plasmid region sufficient for autonomous replication and transformation of infectious Borrelia burgdorferi. Mol Microbiol (2001) 2.95
Effects of environmental pH on membrane proteins in Borrelia burgdorferi. Infect Immun (1999) 2.91
Efficient targeted mutagenesis in Borrelia burgdorferi. J Bacteriol (2000) 2.89
Decorin-binding adhesins from Borrelia burgdorferi. Mol Microbiol (1998) 2.85
Distinct roles of an alternative sigma factor during both free-swimming and colonizing phases of the Vibrio cholerae pathogenic cycle. Mol Microbiol (1998) 2.74
Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC. Infect Immun (1996) 2.49
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect Immun (1998) 2.23
Role of mga in growth phase regulation of virulence genes of the group A streptococcus. J Bacteriol (1997) 2.20
Cell-density-dependent expression of Borrelia burgdorferi lipoproteins in vitro. Infect Immun (1997) 2.19
Standardization of medium for culturing Lyme disease spirochetes. J Clin Microbiol (1993) 2.19
Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Infect Immun (1999) 2.18
DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodies. Infect Immun (1998) 1.99
Differential expression of Borrelia burgdorferi proteins during growth in vitro. Infect Immun (1998) 1.96
Borrelia burgdorferi strain-specific Osp C-mediated immunity in mice. Infect Immun (1997) 1.93
Evolution of the Borrelia burgdorferi outer surface protein OspC. J Bacteriol (1995) 1.81
Development of an extrachromosomal cloning vector system for use in Borrelia burgdorferi. Proc Natl Acad Sci U S A (2000) 1.75
Inhibition of Borrelia burgdorferi migration from the midgut to the salivary glands following feeding by ticks on OspC-immunized mice. Infect Immun (2000) 1.65
DNA analysis of Borrelia burgdorferi NCH-1, the first northcentral U.S. human Lyme disease isolate. J Clin Microbiol (1992) 1.61
Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi. EMBO J (2001) 1.54
Ticks and Borrelia: model systems for investigating pathogen-arthropod interactions. Infect Agents Dis (1996) 1.52
Borrelia burgdorferi proteins whose expression is similarly affected by culture temperature and pH. Infect Immun (2001) 1.49
Altered stationary-phase response in a Borrelia burgdorferi rpoS mutant. J Bacteriol (2000) 1.49
Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Mol Microbiol (2000) 1.43
Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi. J Biol Chem (2001) 1.42
Expression and sequence of outer surface protein C among North American isolates of Borrelia burgdorferi. FEMS Microbiol Lett (1994) 1.29
Current understanding of Lyme disease. Hosp Pract (Off Ed) (1993) 1.10
Regulatory sequences in sigma 54 localise near the start of DNA melting. J Mol Biol (2001) 1.10
Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection. Microbiology (1999) 1.08
Novel roles of sigmaN in small genomes. Microbiology (2000) 1.01
Loss of pathogenic potential after cloning of the low-passage Borrelia burgdorferi ZS7 tick isolate: a cautionary note. Med Microbiol Immunol (1999) 0.91
Antibiotic selective markers and spirochete genetics. J Mol Microbiol Biotechnol (2000) 0.89
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (1999) 8.63
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell Biol (1999) 5.58
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature (1997) 5.45
Factors affecting the transformation of Escherichia coli strain chi1776 by pBR322 plasmid DNA. Gene (1978) 5.15
Cell fate determination in the vertebrate retina. Proc Natl Acad Sci U S A (1996) 4.81
Induction of direct antimicrobial activity through mammalian toll-like receptors. Science (2001) 4.46
Monitoring community responses to the SARS epidemic in Hong Kong: from day 10 to day 62. J Epidemiol Community Health (2003) 4.45
Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins. Infect Immun (1990) 4.10
Effect of mobile phone intervention for diabetes on glycaemic control: a meta-analysis. Diabet Med (2011) 4.04
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science (1998) 3.72
Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell (1993) 3.54
A double mass extinction at the end of the paleozoic era. Science (1994) 3.53
Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114. Infect Immun (1988) 3.42
A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest (1998) 3.41
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J Biol Chem (1994) 3.18
Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum. Proc Natl Acad Sci U S A (1989) 3.17
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res (2000) 3.03
Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol (2000) 3.00
Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem (1998) 2.93
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol (1995) 2.92
An essential Saccharomyces cerevisiae gene homologous to SNF2 encodes a helicase-related protein in a new family. Mol Cell Biol (1992) 2.78
Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins. Circulation (2001) 2.66
Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell (2000) 2.64
Increased amplification of pBR322 plasmid deoxyribonucleic acid in Escherichia coli K-12 strains RR1 and chi1776 grown in the presence of high concentrations of nucleoside. J Bacteriol (1979) 2.55
Sensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol (1991) 2.51
Rapid and simple removal of contaminating RNA from plasmid DNA without the use of RNase. Anal Biochem (1981) 2.51
Proteases for cell suicide: functions and regulation of caspases. Microbiol Mol Biol Rev (2000) 2.48
A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J Cell Biol (1999) 2.46
APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron (2001) 2.31
Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol (2001) 2.24
Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect Immun (1998) 2.23
Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc Natl Acad Sci U S A (1999) 2.20
Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid. J Clin Microbiol (1991) 2.20
Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Infect Immun (1999) 2.18
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. J Biol Chem (2000) 2.17
A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. EMBO J (2000) 2.17
Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J (1996) 2.16
Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell (1997) 2.16
Role of ventilation in airborne transmission of infectious agents in the built environment - a multidisciplinary systematic review. Indoor Air (2007) 2.16
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence. Mol Cell Biol (2001) 2.15
Major integral membrane protein immunogens of Treponema pallidum are proteolipids. Infect Immun (1989) 2.15
Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J Bacteriol (1996) 2.14
Homologous pairs of regulatory proteins control activity of Bacillus subtilis transcription factor sigma(b) in response to environmental stress. J Bacteriol (1996) 2.13
Monoclonal antibody with hemagglutination, immobilization, and neutralization activities defines an immunodominant, 47,000 mol wt, surface-exposed immunogen of Treponema pallidum (Nichols). J Exp Med (1984) 2.11
Taxol from Pestalotiopsis microspora, an endophytic fungus of Taxus wallachiana. Microbiology (1996) 2.10
Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct. J Immunol (1991) 2.09
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ (1996) 2.09
Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols). Infect Immun (1982) 2.08
Acute toxicity and n-octanol/water partition coefficients of substituted thiophenols: determination and QSAR analysis. Ecotoxicol Environ Saf (2011) 2.04
Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression. Genes Dev (2001) 2.01
Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks. Infect Immun (2000) 2.00
PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo. J Virol (1998) 1.99
Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation. Cell (1995) 1.99
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology (2001) 1.98
Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain. Br J Dermatol (2015) 1.96
Cloning and expression of Treponema pallidum (Nichols) antigen genes in Escherichia coli. Infect Immun (1983) 1.94
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. Proc Natl Acad Sci U S A (1998) 1.94
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover. Mol Cell Biol (2000) 1.93
Injecting drug use and HIV infection in southwest China. AIDS (1994) 1.91
Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymerase. J Virol (2000) 1.91
Presenilin-1 regulates neuronal differentiation during neurogenesis. Development (2000) 1.90
Limited surface exposure of Borrelia burgdorferi outer surface lipoproteins. Proc Natl Acad Sci U S A (1996) 1.90
On the cloning of eukaryotic total poly(A)-RNA populations in Escherichia coli. J Biol Chem (1980) 1.89
N-terminal mutations modulate yeast SNF1 protein kinase function. Genetics (1992) 1.88
Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. Ann Surg Oncol (1996) 1.87
Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J Immunol (1995) 1.86
TAZ is a novel oncogene in non-small cell lung cancer. Oncogene (2011) 1.85
Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis. Proc Natl Acad Sci U S A (1996) 1.85
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest (2000) 1.85
Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides. Infect Immun (1999) 1.84
Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev (2000) 1.81
Monoclonal antibody analysis of specific antigenic similarities among pathogenic Treponema pallidum subspecies. Infect Immun (1984) 1.77
Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10. J Immunol (2000) 1.77
Development of an extrachromosomal cloning vector system for use in Borrelia burgdorferi. Proc Natl Acad Sci U S A (2000) 1.75
Decline of physical activity from youth to young adulthood in Finland. Med Sci Sports Exerc (2000) 1.72
IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells. J Orthop Res (2003) 1.67
Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria. Science (1981) 1.67
The diagnosis and treatment of dentinogenic ghost cell tumor. Int J Oral Maxillofac Surg (2009) 1.67
A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase. EMBO J (1998) 1.66
Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete. Infect Immun (1995) 1.66
Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformation. Br J Cancer (1997) 1.65
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene (2000) 1.65
Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. Proc Natl Acad Sci U S A (1998) 1.64
Surface components of Escherichia coli that mediate resistance to the bactericidal activities of serum and phagocytes. Curr Top Microbiol Immunol (1985) 1.63
Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1. Nat Genet (2001) 1.62
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis. J Clin Invest (1999) 1.62
Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy. J Bacteriol (1994) 1.61
A hemoglobin-binding outer membrane protein is involved in virulence expression by Haemophilus ducreyi in an animal model. Infect Immun (1996) 1.60
Evaluation of molecular methodologies and rabbit infectivity testing for the diagnosis of congenital syphilis and neonatal central nervous system invasion by Treponema pallidum. J Infect Dis (1993) 1.60
Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone. Nat Struct Biol (1999) 1.60
Biodegradation of methyl t-butyl ether by pure bacterial cultures. Appl Microbiol Biotechnol (1997) 1.58
Surveying a supercoil domain by using the gamma delta resolution system in Salmonella typhimurium. J Bacteriol (1996) 1.58
Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection. Infect Immun (1997) 1.57