PubRank

Shuichi Takayama

Author PubWeight™ 135.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. Analyst 2010 2.56
2 Computerized microfluidic cell culture using elastomeric channels and Braille displays. Proc Natl Acad Sci U S A 2004 2.51
3 Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy. J Control Release 2012 2.12
4 Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification. Anal Chem 2007 2.10
5 Fabrication of reconfigurable protein matrices by cracking. Nat Mater 2005 2.08
6 Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems. Proc Natl Acad Sci U S A 2007 2.02
7 Microfluidics for flow cytometric analysis of cells and particles. Physiol Meas 2005 2.00
8 Tuneable elastomeric nanochannels for nanofluidic manipulation. Nat Mater 2007 1.96
9 Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells. PLoS One 2009 1.87
10 Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Dev Cell 2002 1.74
11 Computer-controlled microcirculatory support system for endothelial cell culture and shearing. Anal Chem 2005 1.70
12 Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture. Biomed Microdevices 2007 1.55
13 Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids. Biomaterials 2009 1.54
14 Integrated Elastomeric Components for Autonomous Regulation of Sequential and Oscillatory Flow Switching in Microfluidic Devices. Nat Phys 2010 1.49
15 Passively driven integrated microfluidic system for separation of motile sperm. Anal Chem 2003 1.48
16 Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices. Anal Chem 2007 1.45
17 Instantaneous fabrication of arrays of normally closed, adjustable, and reversible nanochannels by tunnel cracking. Lab Chip 2010 1.45
18 Leakage-free bonding of porous membranes into layered microfluidic array systems. Anal Chem 2007 1.39
19 Efficient formation of uniform-sized embryoid bodies using a compartmentalized microchannel device. Lab Chip 2007 1.36
20 Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids. Integr Biol (Camb) 2009 1.33
21 Hard top soft bottom microfluidic devices for cell culture and chemical analysis. Anal Chem 2009 1.32
22 Organs-on-a-chip: a focus on compartmentalized microdevices. Ann Biomed Eng 2011 1.25
23 On being the right size: scaling effects in designing a human-on-a-chip. Integr Biol (Camb) 2013 1.23
24 Flexible fabrication and applications of polymer nanochannels and nanoslits. Chem Soc Rev 2011 1.20
25 The mechanical properties of a surface-modified layer on poly(dimethylsiloxane). J Mater Res 2008 1.19
26 DNA linearization through confinement in nanofluidic channels. Anal Bioanal Chem 2008 1.18
27 Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs. Biomaterials 2009 1.18
28 Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells. Integr Biol (Camb) 2010 1.17
29 Nanoscale squeezing in elastomeric nanochannels for single chromatin linearization. Nano Lett 2012 1.16
30 Guided fracture of films on soft substrates to create micro/nano-feature arrays with controlled periodicity. Sci Rep 2013 1.16
31 Polymeric aqueous biphasic systems for non-contact cell printing on cells: engineering heterocellular embryonic stem cell niches. Adv Mater 2010 1.15
32 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids. Biotechnol Bioeng 2011 1.15
33 The effect of continuous wavy micropatterns on silicone substrates on the alignment of skeletal muscle myoblasts and myotubes. Biomaterials 2006 1.13
34 Quantitative analysis of molecular absorption into PDMS microfluidic channels. Ann Biomed Eng 2012 1.12
35 Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model. Lab Chip 2010 1.11
36 Constant flow-driven microfluidic oscillator for different duty cycles. Anal Chem 2011 1.11
37 External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos. Dev Cell 2013 1.10
38 Next-generation integrated microfluidic circuits. Lab Chip 2011 1.09
39 Phase-locked signals elucidate circuit architecture of an oscillatory pathway. PLoS Comput Biol 2010 1.07
40 Individually programmable cell stretching microwell arrays actuated by a Braille display. Biomaterials 2008 1.06
41 Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation. Analyst 2004 1.06
42 The art of reporter proteins in science: past, present and future applications. BMB Rep 2010 1.04
43 Fabrication of microfluidic mixers and artificial vasculatures using a high-brightness diode-pumped Nd:YAG laser direct write method. Lab Chip 2003 1.04
44 Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip 2005 1.03
45 Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture. J Biomed Opt 2006 1.02
46 IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm. Hum Reprod 2005 1.01
47 Rethinking in vitro embryo culture: new developments in culture platforms and potential to improve assisted reproductive technologies. Biol Reprod 2012 1.00
48 Microfluidic culture of single human embryonic stem cell colonies. Lab Chip 2009 1.00
49 Isolation of motile spermatozoa from semen samples using microfluidics. Reprod Biomed Online 2003 0.99
50 Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves. Lab Chip 2010 0.99
51 Microfluidic applications for andrology. J Androl 2005 0.99
52 Reversible on-demand cell alignment using reconfigurable microtopography. Biomaterials 2008 0.97
53 Micro- and nanotechnologies for studying cellular function. Curr Top Med Chem 2003 0.96
54 Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J 2012 0.95
55 Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change. J Am Chem Soc 2003 0.95
56 Unsteady propagation of a liquid plug in a liquid-lined straight tube. Phys Fluids (1994) 2008 0.95
57 A cost-effective fluorescence mini-microscope for biomedical applications. Lab Chip 2015 0.95
58 Liquid and surfactant delivery into pulmonary airways. Respir Physiol Neurobiol 2008 0.93
59 Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems. Integr Biol (Camb) 2010 0.93
60 Microprinted feeder cells guide embryonic stem cell fate. Biotechnol Bioeng 2011 0.93
61 Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates. Biomed Microdevices 2012 0.92
62 Precisely targeted delivery of cells and biomolecules within microchannels using aqueous two-phase systems. Biomed Microdevices 2011 0.91
63 Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics. Lab Chip 2011 0.90
64 Super-resolution imaging of PDMS nanochannels by single-molecule micelle-assisted blink microscopy. J Phys Chem B 2013 0.90
65 Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies. Adv Funct Mater 2011 0.89
66 Quantitative inference of cellular parameters from microfluidic cell culture systems. Biotechnol Bioeng 2009 0.89
67 Hi-Fi transmission of periodic signals amid cell-to-cell variability. Mol Biosyst 2011 0.89
68 Single cell trapping in larger microwells capable of supporting cell spreading and proliferation. Microfluid Nanofluidics 2010 0.89
69 Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers. Anal Chem 2010 0.88
70 Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns. Lab Chip 2014 0.88
71 Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model. Biomed Microdevices 2011 0.87
72 Transwells with microstamped membranes produce micropatterned two-dimensional and three-dimensional co-cultures. Tissue Eng Part C Methods 2010 0.87
73 Micropatterning bacterial suspensions using aqueous two phase systems. Analyst 2010 0.87
74 Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device. Biomed Microdevices 2010 0.87
75 Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes. Adv Healthc Mater 2013 0.86
76 Small volume low mechanical stress cytometry using computer-controlled Braille display microfluidics. Lab Chip 2007 0.86
77 A surface-modified sperm sorting device with long-term stability. Biomed Microdevices 2006 0.86
78 A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development. Zebrafish 2009 0.86
79 Cell co-culture patterning using aqueous two-phase systems. J Vis Exp 2013 0.86
80 Rapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning. Tissue Eng Part C Methods 2012 0.86
81 Microfluidic oscillators with widely tunable periods. Lab Chip 2013 0.86
82 Micro- and nanofluidic technologies for epigenetic profiling. Biomicrofluidics 2013 0.85
83 Microscale integrated sperm sorter. Methods Mol Biol 2006 0.85
84 Aqueous biphasic microprinting approach to tissue engineering. Biomicrofluidics 2011 0.85
85 Microscale determination of aqueous two phase system binodals by droplet dehydration in oil. Anal Chem 2013 0.85
86 Rethinking gamete/embryo isolation and culture with microfluidics. Hum Reprod Update 2003 0.84
87 Aqueous two-phase printing of cell-containing contractile collagen microgels. Biomaterials 2013 0.84
88 Aqueous two-phase systems enable multiplexing of homogeneous immunoassays. Technology (Singap World Sci) 2014 0.84
89 Responses of endothelial cells to extremely slow flows. Biomicrofluidics 2011 0.83
90 Preprogrammed capillarity to passively control system-level sequential and parallel microfluidic flows. Lab Chip 2013 0.83
91 Control of soft machines using actuators operated by a Braille display. Lab Chip 2013 0.83
92 Pumps for microfluidic cell culture. Electrophoresis 2013 0.83
93 Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation. J Am Chem Soc 2013 0.83
94 External compression-induced fracture patterning on the surface of poly(dimethylsiloxane) cubes and microspheres. Langmuir 2009 0.83
95 Dynamics of liquid plugs of buffer and surfactant solutions in a micro-engineered pulmonary airway model. Langmuir 2010 0.83
96 Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics. Integr Biol (Camb) 2013 0.82
97 Transfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroids. J Lab Autom 2013 0.82
98 Bioengineered three-dimensional physiological model of colonic longitudinal smooth muscle in vitro. Tissue Eng Part C Methods 2010 0.82
99 One-dimensional patterning of cells in silicone wells via compression-induced fracture. J Biomed Mater Res A 2013 0.82
100 Simultaneous fabrication of PDMS through-holes for three-dimensional microfluidic applications. Lab Chip 2010 0.82
101 Patterning bacterial communities on epithelial cells. PLoS One 2013 0.82
102 Aqueous two-phase system-derived biofilms for bacterial interaction studies. Biomacromolecules 2012 0.81
103 Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation. Lab Chip 2012 0.81
104 Room temperature phosphorescence of metal-free organic materials in amorphous polymer matrices. J Am Chem Soc 2013 0.81
105 High-density fabrication of normally closed microfluidic valves by patterned deactivation of oxidized polydimethylsiloxane. Lab Chip 2010 0.81
106 Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip. Biofabrication 2016 0.81
107 Label-free direct visual analysis of hydrolytic enzyme activity using aqueous two-phase system droplet phase transitions. Anal Chem 2014 0.80
108 Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits. Appl Phys Lett 2012 0.80
109 Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow. Anal Chem 2010 0.80
110 Elevating sampling. Lab Chip 2014 0.80
111 Large-scale, ultrapliable, and free-standing nanomembranes. Adv Mater 2013 0.80
112 Patterned electrode-based amperometric gas sensor for direct nitric oxide detection within microfluidic devices. Anal Chem 2010 0.79
113 Microfluidic systems: a new toolbox for pluripotent stem cells. Biotechnol J 2012 0.79
114 Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers. Small 2012 0.79
115 Media additives to promote spheroid circularity and compactness in hanging drop platform. Biomater Sci 2014 0.78
116 Lab-on-a-chip biophotonics: its application to assisted reproductive technologies. J Biophotonics 2012 0.78
117 Localized micro-scale disruption of cells using laser-generated focused ultrasound. J Biophotonics 2013 0.78
118 Recent developments in multiplexing techniques for immunohistochemistry. Expert Rev Mol Diagn 2015 0.78
119 Assessment of sperm chemokinesis with exposure to jelly coats of sea urchin eggs and resact: a microfluidic experiment and numerical study. J Exp Biol 2007 0.77
120 Guided corona generates wettability patterns that selectively direct cell attachment inside closed microchannels. Biomed Microdevices 2010 0.77
121 Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves. Anal Chem 2008 0.77
122 Receptor differential activation and cooperativity better explain cellular preference for different chemoattractant gradient shapes in an EGFR system. Integr Biol (Camb) 2011 0.77
123 Aqueous two-phase system-mediated antibody micropatterning enables multiplexed immunostaining of cell monolayers and tissues. Biotechnol J 2014 0.76
124 Patchy surfaces stabilize dextran-polyethylene glycol aqueous two-phase system liquid patterns. Langmuir 2013 0.76
125 Fracture fabrication of a multi-scale channel device that efficiently captures and linearizes DNA from dilute solutions. Lab Chip 2015 0.75
126 Preprogrammed, parallel on-chip immunoassay using system-level capillarity control. Anal Chem 2013 0.75
127 Dynamic simulations show repeated narrowing maximizes DNA linearization in elastomeric nanochannels. Biomicrofluidics 2016 0.75
128 High-speed tuning of visible laser wavelength using a nanoimprinted grating optical tunable filter. Appl Phys Lett 2009 0.75
129 Supersoft lithography: candy-based fabrication of soft silicone microstructures. Lab Chip 2015 0.75
130 Correction: Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis. PLoS One 2017 0.75
131 Elongation of fibers from highly viscous dextran solutions enables fabrication of rapidly dissolving drug carrying fabrics. Adv Healthc Mater 2014 0.75
132 Dispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures. Biomater Sci 2017 0.75
133 Aqueous two-phase system technology for patterning bacterial communities and biofilms. Methods Mol Biol 2014 0.75
134 Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations. Curr Top Med Chem 2011 0.75