Published in Kidney Int on January 01, 2006
ECM remodeling in hypertensive heart disease. J Clin Invest (2007) 4.03
Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan. J Am Soc Nephrol (2008) 1.93
(Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation. Clin Exp Pharmacol Physiol (2009) 1.83
Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertension. Hypertension (2014) 1.60
Long-term angiotensin II AT1 receptor inhibition produces adipose tissue hypotrophy accompanied by increased expression of adiponectin and PPARgamma. Eur J Pharmacol (2006) 1.40
Role of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease. Am J Nephrol (2010) 1.33
New pharmacological treatments for improving renal outcomes in diabetes. Nat Rev Nephrol (2010) 1.29
A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathy. J Am Soc Nephrol (2008) 1.24
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? Pharmacol Ther (2009) 1.19
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol (2008) 1.19
Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression. Endocrinology (2009) 1.17
Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol (2008) 1.16
The importance of the intrarenal renin-angiotensin system. Nat Clin Pract Nephrol (2008) 1.15
Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist. Am J Physiol Renal Physiol (2009) 1.13
Infusion of angiotensin-(1-7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis. Am J Physiol Renal Physiol (2009) 1.07
Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway. Br J Pharmacol (2008) 1.04
Involvement of (pro)renin receptor in the glomerular filtration barrier. J Mol Med (Berl) (2008) 1.03
Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways. Endocrinology (2010) 1.03
Renal (pro)renin receptor contributes to development of diabetic kidney disease through transforming growth factor-β1-connective tissue growth factor signalling cascade. Clin Exp Pharmacol Physiol (2011) 1.03
Nonclassical renin-angiotensin system and renal function. Compr Physiol (2012) 1.02
Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression. J Am Soc Nephrol (2011) 1.01
Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia. PLoS One (2013) 0.98
The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System? Int J Hypertens (2012) 0.98
Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans. Kidney Int (2009) 0.98
New roles for renin and prorenin in heart failure and cardiorenal crosstalk. Heart Fail Rev (2012) 0.98
PAI-1 and kidney fibrosis. Front Biosci (Landmark Ed) (2009) 0.97
High glucose induces podocyte injury via enhanced (pro)renin receptor-Wnt-β-catenin-snail signaling pathway. PLoS One (2014) 0.97
(Pro)renin receptor mediates both angiotensin II-dependent and -independent oxidative stress in neuronal cells. PLoS One (2013) 0.97
Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches. Eur Heart J (2011) 0.95
Direct renin inhibition and the kidney. Nat Rev Nephrol (2009) 0.94
Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells. J Renin Angiotensin Aldosterone Syst (2014) 0.93
Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab (2008) 0.93
In vivo regulation of renal expression of (pro)renin receptor by a low-sodium diet. Am J Physiol Renal Physiol (2012) 0.93
Serum level of soluble (pro)renin receptor is modulated in chronic kidney disease. Clin Exp Nephrol (2013) 0.92
Key developments in renin-angiotensin-aldosterone system inhibition. Nat Rev Nephrol (2012) 0.91
The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction. Vasc Health Risk Manag (2008) 0.90
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat. Am J Physiol Renal Physiol (2009) 0.89
Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice. Lab Invest (2014) 0.87
Receptor-mediated nonproteolytic activation of prorenin and induction of TGF-β1 and PAI-1 expression in renal mesangial cells. Am J Physiol Renal Physiol (2012) 0.86
Antioxidants in kidney diseases: the impact of bardoxolone methyl. Int J Nephrol (2012) 0.86
Autophagy and the (Pro)renin Receptor. Front Endocrinol (Lausanne) (2013) 0.85
Recent advances in tissue (pro)renin imaging. Front Biosci (Elite Ed) (2010) 0.85
Direct renin inhibition--a promising strategy for renal protection? Med Sci Monit (2013) 0.84
Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis. Am J Physiol Renal Physiol (2011) 0.84
Indoxyl sulfate-induced activation of (pro)renin receptor promotes cell proliferation and tissue factor expression in vascular smooth muscle cells. PLoS One (2014) 0.84
Inhibition of renin activity slows down the progression of HIV-associated nephropathy. Am J Physiol Renal Physiol (2012) 0.84
Cellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its Comorbidities. Front Immunol (2015) 0.84
Application of direct renin inhibition to chronic kidney disease. Cardiovasc Drugs Ther (2010) 0.84
Inhibition of RAS in diabetic nephropathy. Int J Nephrol Renovasc Dis (2015) 0.84
Calcitriol, calcidiol, parathyroid hormone, and fibroblast growth factor-23 interactions in chronic kidney disease. J Vet Emerg Crit Care (San Antonio) (2013) 0.83
Lessons From the KK-Ay Mouse, a Spontaneous Animal Model for the Treatment of Human Type 2 Diabetic Nephropathy. Nephrourol Mon (2012) 0.83
Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors. Vasc Health Risk Manag (2009) 0.81
The (pro)renin receptor. A decade of research: what have we learned? Pflugers Arch (2012) 0.81
Glioblastoma Multiforme Cancer Stem Cells Express Components of the Renin-Angiotensin System. Front Surg (2016) 0.81
Receptor-mediated actions of renin and prorenin. Kidney Int (2006) 0.79
Modulation of glomerulosclerosis. Semin Immunopathol (2007) 0.79
The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats. J Cell Mol Med (2009) 0.79
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. Am J Physiol Heart Circ Physiol (2009) 0.79
Role of (pro)renin receptor in Ang II-mediated EGF receptor transactivation. Front Biosci (Elite Ed) (2013) 0.79
Effect of aldosterone and its antagonist on the expression of PAI-1 and TGF-β1 in rat hepatic stellate cells. Int J Clin Exp Med (2014) 0.79
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. Oxid Med Cell Longev (2016) 0.78
(Pro)renin Receptor in Kidney Development and Disease. Int J Nephrol (2011) 0.78
Combined renin inhibition/(pro)renin receptor blockade in diabetic retinopathy--a study in transgenic (mREN2)27 rats. PLoS One (2014) 0.78
Effects of direct Renin inhibition on myocardial fibrosis and cardiac fibroblast function. PLoS One (2013) 0.78
Assessing the application of tissue microarray technology to kidney research. J Histochem Cytochem (2010) 0.78
Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis. Kidney Int (2016) 0.78
Prorenin anno 2008. J Mol Med (Berl) (2008) 0.78
Wnt/β-catenin signaling and renin-angiotensin system in chronic kidney disease. Curr Opin Nephrol Hypertens (2016) 0.78
This is not Dr. Conn's aldosterone anymore. Trans Am Clin Climatol Assoc (2011) 0.77
Dual renin-angiotensin-aldosterone system blockade for diabetic kidney disease. Curr Diab Rep (2010) 0.77
Role of aliskiren in blood pressure control and renoprotection. Int J Nephrol Renovasc Dis (2011) 0.77
Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses. PLoS One (2013) 0.77
Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR. PLoS One (2016) 0.77
Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cells. Am J Physiol Renal Physiol (2012) 0.76
Renin and cardiovascular disease: Worn-out path, or new direction. World J Cardiol (2011) 0.76
Interaction between V-ATPase B2 and (Pro) renin Receptors in Promoting the progression of Renal Tubulointerstitial Fibrosis. Sci Rep (2016) 0.75
Effect of the Direct Renin Inhibitor Aliskiren on Urinary Albumin Excretion in Spontaneous Type 2 Diabetic KK-A (y) Mouse. Int J Nephrol (2013) 0.75
Higher plasma prorenin concentration plays a role in the development of coronary artery disease. Biomark Res (2015) 0.75
Mechanisms underlying prorenin actions on hypothalamic neurons implicated in cardiometabolic control. Mol Metab (2016) 0.75
A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats. Diabetes Metab Syndr Obes (2016) 0.75
Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal injury in unilateral ureteral obstructed mice. Korean J Intern Med (2016) 0.75
Possible contribution of (pro)renin receptor to development of gestational diabetes mellitus. World J Diabetes (2014) 0.75
Pulmonary toxicity generated from radiotherapeutic treatment of thoracic malignancies. Oncol Lett (2017) 0.75
The long-term complications of the inherited tubulopathies: an adult perspective. Pediatr Nephrol (2014) 0.75
Is the renin-angiotensin system actually hypertensive? Pediatr Nephrol (2013) 0.75
Efficacy of add-on therapy of aliskiren to an angiotensin II receptor blocker on renal outcomes in advanced-stage chronic kidney disease: a prospective, randomized, open-label study. Clin Exp Nephrol (2014) 0.75
A-TYPE POTASSIUM CHANNELS CONTRIBUTE TO PRORENIN INCREASE OF FIRING ACTIVITY IN HYPOTHALAMIC VASOPRESSIN NEUROSECRETORY NEURONS. Am J Physiol Heart Circ Physiol (2017) 0.75
Transforming growth factor beta in tissue fibrosis. N Engl J Med (1994) 9.73
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet (2000) 8.58
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet (1999) 7.30
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science (2000) 6.73
Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell (1999) 4.83
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A (1998) 4.67
Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes (1996) 4.20
Total daily physical activity and the risk of AD and cognitive decline in older adults. Neurology (2012) 4.09
Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria. Science (1997) 4.07
Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature (1992) 3.96
The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J Biol Chem (2000) 3.49
Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci U S A (1993) 3.16
Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans. Nat Med (1998) 3.11
Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Aliment Pharmacol Ther (2014) 2.88
Influence of smoking fewer cigarettes on exposure to tar, nicotine, and carbon monoxide. N Engl J Med (1986) 2.87
Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest (1994) 2.81
GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci U S A (1999) 2.80
Studies on cytochrome oxidase. Interactions of the cytochrome oxidase protein with phospholipids and cytochrome c. J Biol Chem (1975) 2.80
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol (1994) 2.70
X-ray diffraction of actively shortening muscle. Proc Natl Acad Sci U S A (1976) 2.59
Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Mol Pharmacol (1993) 2.54
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol (2000) 2.40
MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem Biophys Res Commun (2008) 2.15
Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans. Biol Mass Spectrom (1991) 2.10
Human galectin-3 is a novel chemoattractant for monocytes and macrophages. J Immunol (2000) 2.06
Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux. Lancet (1999) 2.02
TGF-beta in kidney fibrosis: a target for gene therapy. Kidney Int (1997) 2.01
Linker histones are not essential and affect chromatin condensation in vivo. Cell (1995) 1.99
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol (2011) 1.98
Human antibody responses to VlsE antigenic variation protein of Borrelia burgdorferi. J Clin Microbiol (1999) 1.95
Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat Med (1996) 1.93
Interactions of transforming growth factor-beta and angiotensin II in renal fibrosis. Hypertension (1998) 1.90
Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. J Virol (1996) 1.89
Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein. Structure (2000) 1.87
Hydrogenase measurement with photochemically reduced methyl viologen. J Bacteriol (1969) 1.85
Improved dual-energy material discrimination for dual-source CT by means of additional spectral filtration. Med Phys (2009) 1.85
Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice. J Pathol (2008) 1.84
Expression of transforming growth factor-beta isoforms in human glomerular diseases. Kidney Int (1996) 1.81
Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis. Lab Invest (1995) 1.79
Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int (2007) 1.76
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int (1999) 1.76
Ace is a collagen-binding MSCRAMM from Enterococcus faecalis. J Biol Chem (1999) 1.73
Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis. Kidney Int (1994) 1.70
Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes. J Autoimmun (1996) 1.68
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9. Oncogene (2010) 1.65
Inhibitor binding changes domain mobility in the iron-sulfur protein of the mitochondrial bc1 complex from bovine heart. Proc Natl Acad Sci U S A (1998) 1.65
Tumor necrosis factor alpha in children with sickle cell disease in stable condition. J Natl Med Assoc (1997) 1.63
Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data. Pharmacogenomics J (2002) 1.63
One third of HLA DQ2 homozygous patients with type 1 diabetes express celiac disease-associated transglutaminase autoantibodies. J Autoimmun (1999) 1.62
Generation of superoxide anion by succinate-cytochrome c reductase from bovine heart mitochondria. J Biol Chem (1998) 1.61
Biology's new Rosetta stone. Nature (1997) 1.59
The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development (1999) 1.59
Occult lumbar lateral spinal stenosis in neural foramina subjected to physiologic loading. AJNR Am J Neuroradiol (1996) 1.58
Late progression to diabetes and evidence for chronic beta-cell autoimmunity in identical twins of patients with type I diabetes. Diabetes (1995) 1.55
Pathologic evaluation of sentinel lymph nodes in colorectal carcinoma. Arch Pathol Lab Med (2000) 1.55
Multiple binding sites in collagen type I for the integrins alpha1beta1 and alpha2beta1. J Biol Chem (2000) 1.54
Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis. Oncogene (2011) 1.54
Intrarectal administration of mCRAMP-encoding plasmid reverses exacerbated colitis in Cnlp(-/-) mice. Gene Ther (2012) 1.53
ICA512 autoantibody radioassay. Diabetes (1995) 1.52
Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. Am J Public Health (1999) 1.52
Processing and maturation of flavocytochrome b558 include incorporation of heme as a prerequisite for heterodimer assembly. J Biol Chem (2000) 1.51
Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States. Diabetologia (2001) 1.49
Prognosis evaluation in alpha-fetoprotein negative hepatocellular carcinoma after hepatectomy: comparison of five staging systems. Eur J Surg Oncol (2010) 1.49
Acute kidney injury prediction following elective cardiac surgery: AKICS Score. Kidney Int (2007) 1.49
Fano resonance for Anderson impurity systems. Phys Rev Lett (2004) 1.48
Lack of association between early childhood immunizations and beta-cell autoimmunity. Diabetes Care (1999) 1.47
Reduced tar, nicotine, and carbon monoxide exposure while smoking ultralow- but not low-yield cigarettes. JAMA (1986) 1.45
T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats. Neuroscience (2004) 1.45
Solution structure of the cyclosporin A/cyclophilin complex by NMR. Nature (1993) 1.44
The circulatory responses to fibreoptic intubation: a comparison of oral and nasal routes. Anaesthesia (2006) 1.44
Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi. J Biol Chem (2001) 1.42
The mechanical effectiveness of erect and "bent-hip, bent-knee" bipedal walking in Australopithecus afarensis. J Hum Evol (1998) 1.41
Selected chitinase genes in cultured and uncultured marine bacteria in the alpha- and gamma-subclasses of the proteobacteria. Appl Environ Microbiol (2000) 1.41
Infusion of glycine does not attenuate in vivo ischemic acute renal failure in the rat. J Lab Clin Med (1993) 1.40
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies. Brain (2012) 1.40
Cardiogenic shock with takotsubo-like cardiomyopathy in functional retroperitoneal paraganglioma. Herz (2014) 1.38
Selective nucleation and discovery of organic polymorphs through epitaxy with single crystal substrates. J Am Chem Soc (2001) 1.37
Biochemical and evolutionary significance of phospholipid methylation. J Biol Chem (1998) 1.37
Masking of Bacillus megaterium KM membrane reduced nicotinamide adenine dinucleotide oxidase and solubilization studies. J Bacteriol (1970) 1.36
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China. Diabetologia (2009) 1.34
Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. Biochem J (1993) 1.34
Divalent cation activation of deoxycholate-solubilized and -inactivated membrane reduced nicotinamide adenine dinucleotide oxidase of Bacillus megaterium KM. J Bacteriol (1970) 1.33
Glomerular matrix accumulation is linked to inhibition of the plasmin protease system. Kidney Int (1992) 1.32
Generation of high-titer defective HSV-1 vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells. Biotechniques (1996) 1.28
MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. Oncogene (2011) 1.27
Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies. J Clin Endocrinol Metab (2006) 1.27
Function and organization of photosystem I in a cyanobacterial mutant strain that lacks PsaF and PsaJ subunits. J Biol Chem (1994) 1.27
Kinetics of electron transfer between cardiac cytochrome c 1 and c. J Biol Chem (1973) 1.26
Mouse muscle nicotinic acetylcholine receptor gamma subunit: cDNA sequence and gene expression. Nucleic Acids Res (1986) 1.24
RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell. Proc Natl Acad Sci U S A (1996) 1.23
The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activity. J Biol Chem (1994) 1.23
Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett (1994) 1.23
Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries. Proc Natl Acad Sci U S A (1995) 1.23
Differential regulation by cAMP-dependent protein kinase and protein kinase C of the mu opioid receptor coupling to a G protein-activated K+ channel. J Biol Chem (1994) 1.22
Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (1995) 1.21
Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China. Vet Parasitol (2011) 1.20
Solution structure of the ets domain of Fli-1 when bound to DNA. Nat Struct Biol (1994) 1.20