Published in Am J Pathol on March 01, 2000
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci U S A (2006) 2.75
Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest (2003) 2.18
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med (2011) 2.09
Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens. J Biol Chem (2008) 2.02
Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile. Proc Natl Acad Sci U S A (2003) 1.84
Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol Cell Biol (2004) 1.63
Glycosylation in immune cell trafficking. Immunol Rev (2009) 1.61
Galectins as inflammatory mediators. Glycoconj J (2004) 1.52
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
When galectins recognize glycans: from biochemistry to physiology and back again. Biochemistry (2011) 1.34
Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death. Cell Death Differ (2004) 1.29
Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function. Am J Pathol (2008) 1.28
Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology. Glycoconj J (2009) 1.28
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways. J Biol Chem (2008) 1.20
Regulation of cellular homeostasis by galectins. Glycoconj J (2004) 1.20
Galectin-3 protects human breast carcinoma cells against nitric oxide-induced apoptosis: implication of galectin-3 function during metastasis. Am J Pathol (2001) 1.19
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol (2008) 1.13
Galectin-3 modulates immune and inflammatory responses during helminthic infection: impact of galectin-3 deficiency on the functions of dendritic cells. Infect Immun (2007) 1.12
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis. Am J Physiol Renal Physiol (2010) 1.10
Seeing strangers or announcing "danger": galectin-3 in two models of innate immunity. Glycoconj J (2004) 1.10
Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis. Mol Cell Biol (2006) 1.09
Allergen-induced airway remodeling is impaired in galectin-3-deficient mice. J Immunol (2010) 1.07
CD13 is a novel mediator of monocytic/endothelial cell adhesion. J Leukoc Biol (2008) 1.07
Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol Biol Cell (2005) 1.07
Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol (2009) 1.03
Galectin-3 gene inactivation reduces atherosclerotic lesions and adventitial inflammation in ApoE-deficient mice. Am J Pathol (2007) 1.02
LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. PLoS One (2011) 1.01
Deletion of galectin-3 in the host attenuates metastasis of murine melanoma by modulating tumor adhesion and NK cell activity. Clin Exp Metastasis (2011) 0.99
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol (2007) 0.99
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
Characterization of inflammatory gene expression and galectin-3 function after spinal cord injury in mice. Brain Res (2012) 0.98
Galectin-1 research in T cell immunity: past, present and future. Clin Immunol (2011) 0.98
Extracellular galectin-3 in tumor progression and metastasis. Front Oncol (2014) 0.97
Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling. Biochem J (2004) 0.97
Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production. Toxicol Sci (2012) 0.96
Galectin-3 binds Neisseria meningitidis and increases interaction with phagocytic cells. Cell Microbiol (2012) 0.95
Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor. Gut (2006) 0.95
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Exp Diabetes Res (2007) 0.94
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am J Physiol Gastrointest Liver Physiol (2011) 0.94
Galectin-3: its role in asthma and potential as an anti-inflammatory target. Respir Res (2013) 0.93
Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. J Invest Dermatol (2008) 0.93
Mechano-transduction mediated secretion and uptake of galectin-3 in breast carcinoma cells: implications in the extracellular functions of the lectin. Exp Cell Res (2006) 0.93
Galectin-3 associates with the primary cilium and modulates cyst growth in congenital polycystic kidney disease. Am J Pathol (2006) 0.92
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice. Glycobiology (2013) 0.90
Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis. Am J Pathol (2016) 0.89
Insect galectins: roles in immunity and development. Glycoconj J (2004) 0.89
Galectins in parasite infection and allergic inflammation. Glycoconj J (2004) 0.88
Shedding light on the immunomodulatory properties of galectins: novel regulators of innate and adaptive immune responses. Glycoconj J (2004) 0.87
The coming of age of galectins as immunomodulatory agents: impact of these carbohydrate binding proteins in T cell physiology and chronic inflammatory disorders. Ann Rheum Dis (2005) 0.87
Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity. PLoS One (2009) 0.87
Novel neuroinflammatory targets in the chronically injured spinal cord. Neurotherapeutics (2011) 0.87
Detection of galectin-3 in tear fluid at disease states and immunohistochemical and lectin histochemical analysis in human corneal and conjunctival epithelium. Br J Ophthalmol (2001) 0.86
Microglia/macrophage-derived inflammatory mediators galectin-3 and quinolinic acid are elevated in cerebrospinal fluid from newborn infants after birth asphyxia. Transl Stroke Res (2012) 0.86
Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Brain Behav (2012) 0.86
Regulation of galectin-3 function in mucosal fibroblasts: potential role in mucosal inflammation. Clin Exp Immunol (2008) 0.86
Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages. Cancer Med (2014) 0.85
Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers. PLoS One (2013) 0.85
Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study. J Cancer Res Clin Oncol (2008) 0.85
Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines. Am J Pathol (2013) 0.85
KSHV downregulation of galectin-3 in Kaposi's sarcoma. Glycobiology (2009) 0.85
Murine model of dextran sulfate sodium-induced colitis reveals Candida glabrata virulence and contribution of β-mannosyltransferases. J Biol Chem (2012) 0.85
Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress. Cell Death Differ (2014) 0.84
Galectin-3 in cord blood of term and preterm infants. Clin Exp Immunol (2012) 0.84
Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia. PLoS One (2013) 0.83
Expression of galectins-1, -3 and -4 varies with strain and type of experimental colitis in mice. Int J Exp Pathol (2008) 0.82
Galectin 3 regulates HCC cell invasion by RhoA and MLCK activation. Lab Invest (2015) 0.82
Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease. ScientificWorldJournal (2012) 0.82
Galectin-3 Plays an Important Role in Innate Immunity to Gastric Infection by Helicobacter pylori. Infect Immun (2016) 0.82
Regulatory role of hypoxia inducible factor in the biological behavior of nucleus pulposus cells. Yonsei Med J (2013) 0.82
The road less traveled: regulation of leukocyte migration across vascular and lymphatic endothelium by galectins. J Clin Immunol (2010) 0.81
Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. PLoS One (2011) 0.81
Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets. Adipocyte (2013) 0.81
Modified apple polysaccharide prevents against tumorigenesis in a mouse model of colitis-associated colon cancer: role of galectin-3 and apoptosis in cancer prevention. Eur J Nutr (2011) 0.81
Serum galectin-3 level in systemic sclerosis. Clin Rheumatol (2013) 0.80
The role of galectin-3 and galectin-3-binding protein in venous thrombosis. Blood (2014) 0.80
Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice. Invest Ophthalmol Vis Sci (2009) 0.80
Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding. Mol Immunol (2015) 0.79
A novel phenylpyridazinone, T-3999, reduces the progression of autoimmune myocarditis to dilated cardiomyopathy. Heart Vessels (2010) 0.79
Galectin-3 Is Elevated and Associated With Adverse Outcomes in Patients With Single-Ventricle Fontan Circulation. J Am Heart Assoc (2016) 0.78
The bone marrow compartment is modified in the absence of galectin-3. Cell Tissue Res (2011) 0.78
The inactive form of glycogen synthase kinase-3β is associated with the development of carcinomas in galectin-3 wild-type mice, but not in galectin-3-deficient mice. Int J Clin Exp Pathol (2012) 0.78
The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase. PLoS One (2011) 0.78
Differential development of oil granulomas induced by pristane injection in galectin-3 deficient mice. BMC Immunol (2015) 0.77
Galectin-3 in autoimmunity and autoimmune diseases. Exp Biol Med (Maywood) (2015) 0.77
The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis. BMC Cancer (2016) 0.77
Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine. J Vet Sci (2009) 0.77
Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.77
Eosinophil-expressed galectin-3 regulates cell trafficking and migration. Front Pharmacol (2013) 0.77
Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis (2012) 0.76
Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis. Stem Cells Int (2016) 0.76
Galectin-3 regulates inflammasome activation in cholestatic liver injury. FASEB J (2016) 0.76
The Cek1‑mediated MAP kinase pathway regulates exposure of α‑1,2 and β‑1,2‑mannosides in the cell wall of Candida albicans modulating immune recognition. Virulence (2016) 0.76
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling. Mol Cell Biol (2016) 0.75
Expression of APC protein during tongue malignant transformation in galectin-3-deficient mice challenged by the carcinogen 4-nitroquniline-n-oxide. Int J Clin Exp Pathol (2014) 0.75
Porifera Lectins: Diversity, Physiological Roles and Biotechnological Potential. Mar Drugs (2015) 0.75
Lack of galectin-1 or galectin-3 alters B cell deletion and anergy in an autoantibody transgene model. Glycobiology (2013) 0.75
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