Published in Cancer on February 01, 2006
Mean telomere length and risk of incident colorectal carcinoma: a prospective, nested case-control approach. Cancer Epidemiol Biomarkers Prev (2009) 1.54
Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers. Br J Cancer (2010) 1.30
Mean leukocyte telomere length and risk of incident colorectal carcinoma in women: a prospective, nested case-control study. Clin Chem Lab Med (2010) 1.14
Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer. J Cancer Res Clin Oncol (2010) 1.02
Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer. Mol Cancer (2011) 0.97
Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer. Br J Cancer (2013) 0.94
PinX1: a sought-after major tumor suppressor at human chromosome 8p23. Oncotarget (2011) 0.92
MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer. Carcinogenesis (2011) 0.90
Telomeres and telomere dynamics: relevance to cancers of the GI tract. Expert Rev Gastroenterol Hepatol (2013) 0.87
Telomeres, telomerase and colorectal cancer. World J Gastroenterol (2014) 0.87
Telomerase activity in human brain tumors: astrocytoma and meningioma. Cell Mol Neurobiol (2013) 0.83
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity. J Exp Clin Cancer Res (2014) 0.82
The Association between Telomere Length and Cancer Prognosis: Evidence from a Meta-Analysis. PLoS One (2015) 0.81
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status. J Exp Clin Cancer Res (2015) 0.80
Telomere function in colorectal cancer. World J Gastrointest Oncol (2009) 0.79
hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells. Oncol Lett (2011) 0.79
Potential clinical role of telomere length in human glioblastoma. Transl Med UniSa (2011) 0.78
Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer. PLoS One (2016) 0.78
Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer. Oncotarget (2016) 0.77
Correlations of telomere length, P53 mutation, and chromosomal translocation in soft tissue sarcomas. Int J Clin Exp Pathol (2015) 0.76
The Relationship between Telomerase Activity and Clinicopathological Parameters in Colorectal Cancer: A Meta-Analysis. Balkan Med J (2016) 0.75
Telomere length modulation in human astroglial brain tumors. PLoS One (2013) 0.75
Association between telomere length and the risk of colorectal cancer: a meta-analysis of observational studies. BMC Cancer (2017) 0.75
Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis. Int J Mol Sci (2017) 0.75
Meta-analysis of associations between telomere length and colorectal cancer survival from observational studies. Oncotarget (2017) 0.75
[Bilateral suprarenal hematoma in a 46-year-old male]. Med Clin (Barc) (2008) 2.02
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes. Mol Cancer Res (2002) 2.01
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol (2008) 1.65
P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol Biol Cell (2003) 1.65
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes. Diabetes (2003) 1.51
Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function. Biochem J (2013) 1.46
[Acute behavior disorder and hypopotassemia in a 49-year-old male]. Med Clin (Barc) (2006) 1.39
Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action. Bioessays (2002) 1.30
Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior. BMC Cancer (2012) 1.23
Chemotherapy for gastric cancer. World J Gastroenterol (2006) 1.13
Portal cholangiopathy: radiological classification and natural history. Gut (2011) 1.04
Telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer. Lung Cancer (2008) 1.03
Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes. Endocrinology (2006) 1.02
Insulin restores differentiation of Ras-transformed C2C12 myoblasts by inducing NF-kappaB through an AKT/P70S6K/p38-MAPK pathway. Oncogene (2002) 1.02
Prevalence of germline mutations of MLH1 and MSH2 in hereditary nonpolyposis colorectal cancer families from Spain. Int J Cancer (2002) 1.02
Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes. J Biol Chem (2002) 1.00
Circulating tumor cells in solid tumor in metastatic and localized stages. Anticancer Res (2009) 1.00
Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes. Exp Cell Res (2004) 1.00
Levels of protein tyrosine phosphatase 1B determine susceptibility to apoptosis in serum-deprived hepatocytes. J Cell Physiol (2007) 1.00
IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes. Hepatology (2004) 0.98
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer. Oncol Rep (2007) 0.98
Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer. Oncol Rep (2004) 0.98
Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer. Mol Cancer (2011) 0.97
Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat (2009) 0.97
Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform. Diabetes (2009) 0.96
Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer. J Clin Oncol (2002) 0.94
Differential Wnt pathway gene expression and E-cadherin truncation in sporadic colorectal cancers with and without microsatellite instability. Clin Cancer Res (2008) 0.94
Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes. J Biol Chem (2003) 0.94
Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1. Cell Signal (2006) 0.93
Capecitabine/oxaliplatin, a safe and active first-line regimen for older patients with metastatic colorectal cancer: post hoc analysis of a large phase II study. Clin Colorectal Cancer (2005) 0.93
Overexpression of SPARC protein contrasts with its transcriptional silencing by aberrant hypermethylation of SPARC CpG-rich region in endometrial carcinoma. Oncol Rep (2007) 0.93
Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes. Diabetes (2002) 0.93
Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death. Autophagy (2012) 0.92
The brown adipose cell: a unique model for understanding the molecular mechanism of insulin resistance. Mini Rev Med Chem (2005) 0.91
Differential colorectal carcinogenesis: Molecular basis and clinical relevance. World J Gastrointest Oncol (2010) 0.90
Low prevalence of germline hMSH6 mutations in colorectal cancer families from Spain. World J Gastroenterol (2005) 0.90
E47 and Id1 interplay in epithelial-mesenchymal transition. PLoS One (2013) 0.88
Susceptibility to apoptosis in insulin-like growth factor-I receptor-deficient brown adipocytes. Mol Biol Cell (2004) 0.87
Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer. Mol Cancer (2014) 0.87
Methylation profiling in non-small cell lung cancer: clinical implications. Int J Oncol (2011) 0.86
Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation. Endocrinology (2003) 0.85
Role of insulin receptor and balance in insulin receptor isoforms A and B in regulation of apoptosis in simian virus 40-immortalized neonatal hepatocytes. Mol Biol Cell (2008) 0.85
Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes. Endocrinology (2006) 0.84
Brown fat lipoatrophy and increased visceral adiposity through a concerted adipocytokines overexpression induces vascular insulin resistance and dysfunction. Endocrinology (2012) 0.84
cIAP-1, but not XIAP, is cleaved by caspases during the apoptosis induced by TGF-beta in fetal rat hepatocytes. FEBS Lett (2002) 0.84
C3G down-regulates p38 MAPK activity in response to stress by Rap-1 independent mechanisms: involvement in cell death. Cell Signal (2010) 0.84
Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors. Cancer Res (2002) 0.83
Differential role of PPAR gamma in the regulation of UCP-1 and adipogenesis by TNF-alpha in brown adipocytes. FEBS Lett (2002) 0.83
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity. J Exp Clin Cancer Res (2014) 0.82
MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway. Int J Oncol (2010) 0.82
Expression of MMP-9 and TIMP-1 as prognostic markers in gastric carcinoma. Hepatogastroenterology (2007) 0.82
Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors. Oncogene (2002) 0.82
Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Endocrinology (2010) 0.82
Phase II study of pegylated liposomal doxorubicin plus vinorelbine in breast cancer with previous anthracycline exposure. Clin Breast Cancer (2004) 0.82
PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes. Am J Physiol Gastrointest Liver Physiol (2008) 0.82
p38alpha MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum. FEBS Lett (2007) 0.81
Atypical beta-adrenergic effects on insulin signaling and action in beta(3)-adrenoceptor-deficient brown adipocytes. Am J Physiol Endocrinol Metab (2002) 0.81
Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications. Int J Oncol (2004) 0.80
Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition. Oncology (2012) 0.80
Implication of insulin receptor A isoform and IRA/IGF-IR hybrid receptors in the aortic vascular smooth muscle cell proliferation: role of TNF-α and IGF-II. Endocrinology (2013) 0.80
Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage. Cardiovasc Diabetol (2014) 0.79
Telomere function in colorectal cancer. World J Gastrointest Oncol (2009) 0.79
Diagnosis of diabetes remission after bariatic surgery may be jeopardized by remission criteria and previous hypoglycemic treatment. Obes Surg (2013) 0.78
Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes. J Biol Chem (2003) 0.78
Expression of Human MDGA1 Increases Cell Motility and Cell-Cell Adhesion and Reduces Adhesion to Extracellular Matrix Proteins in MDCK Cells. Cancer Microenviron (2010) 0.78
IRS-3 mediates insulin-induced glucose uptake in differentiated IRS-2(-/-) brown adipocytes. Mol Cell Endocrinol (2006) 0.77
Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress. Endocrinology (2003) 0.77
Impairment of stromelysin-1 transcriptional activity by promoter mutations in high microsatellite instability colorectal tumors. Cancer Res (2005) 0.77
Statistical models to predict type 2 diabetes remission after bariatric surgery. J Diabetes (2014) 0.77