Published in Hum Mol Genet on January 06, 2006
Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seq. BMC Genomics (2015) 1.41
Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad. PLoS Genet (2012) 1.38
X chromosome activity in mouse XX primordial germ cells. PLoS Genet (2008) 1.38
Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis. PLoS One (2011) 1.32
GeneChaser: identifying all biological and clinical conditions in which genes of interest are differentially expressed. BMC Bioinformatics (2008) 1.24
Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol (2009) 1.23
Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination. Am J Hum Genet (2010) 1.21
Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice. Development (2008) 1.17
Mammalian sex determination—insights from humans and mice. Chromosome Res (2012) 1.14
Disorders of sex development: new genes, new concepts. Nat Rev Endocrinol (2012) 1.12
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal. Genes Dev (2009) 1.10
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
To beta or not to beta: canonical beta-catenin signaling pathway and ovarian development. Dev Dyn (2008) 1.09
Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice. Mech Dev (2009) 1.05
Identification of novel markers of mouse fetal ovary development. PLoS One (2012) 1.03
Human RSPO1/R-spondin1 is expressed during early ovary development and augments β-catenin signaling. PLoS One (2011) 0.99
Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation. Reprod Biol Endocrinol (2011) 0.95
Testicular postgenomics: targeting the regulation of spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 0.94
Developmental staging of male murine embryonic gonad by SAGE analysis. J Genet Genomics (2009) 0.94
Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of mammalian sex determination. PLoS Genet (2013) 0.91
New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation. Biol Reprod (2009) 0.91
Building pathways for ovary organogenesis in the mouse embryo. Curr Top Dev Biol (2010) 0.90
The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice. Biol Reprod (2009) 0.90
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet (2013) 0.87
Uncovering gene regulatory networks during mouse fetal germ cell development. Biol Reprod (2010) 0.86
Sex and the circuitry: progress toward a systems-level understanding of vertebrate sex determination. Wiley Interdiscip Rev Syst Biol Med (2012) 0.84
Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. Dev Dyn (2009) 0.84
Translational genetics for diagnosis of human disorders of sex development. Annu Rev Genomics Hum Genet (2013) 0.83
Global survey of protein expression during gonadal sex determination in mice. Mol Cell Proteomics (2009) 0.83
FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J (2014) 0.82
Long-term effects of early-life exposure to environmental oestrogens on ovarian function: role of epigenetics. J Neuroendocrinol (2014) 0.82
The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice. PLoS One (2008) 0.82
Mammalian testis-determining factor SRY and the enigma of inherited human sex reversal: frustrated induced fit in a bent protein-DNA complex. J Biol Chem (2011) 0.82
NOTCH signaling in Sertoli cells regulates gonocyte fate. Cell Cycle (2013) 0.81
Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach. Mol Endocrinol (2014) 0.80
Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis. Dev Dyn (2009) 0.80
Gadd45g is essential for primary sex determination, male fertility and testis development. PLoS One (2013) 0.78
Gender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD. PLoS One (2012) 0.77
A Boolean network model of human gonadal sex determination. Theor Biol Med Model (2015) 0.76
Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos. PLoS One (2015) 0.76
A genomic atlas of human adrenal and gonad development. Wellcome Open Res (2017) 0.75
Regulation of germ line stem cell homeostasis. Anim Reprod (2017) 0.75
Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation. PLoS One (2017) 0.75
Retinoid signaling determines germ cell fate in mice. Science (2006) 4.17
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell (2002) 3.39
Sox18 induces development of the lymphatic vasculature in mice. Nature (2008) 2.91
Sex determination and gonadal development in mammals. Physiol Rev (2007) 2.60
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opin Genet Dev (2002) 2.24
Expression of distinct RNAs from 3' untranslated regions. Nucleic Acids Res (2010) 2.08
Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice. J Cell Sci (2006) 2.05
Genesis and expansion of metazoan transcription factor gene classes. Mol Biol Evol (2008) 2.01
Retinoic acid, meiosis and germ cell fate in mammals. Development (2007) 1.91
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone (2005) 1.68
Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos. Biochem Biophys Res Commun (2007) 1.68
FGF9 suppresses meiosis and promotes male germ cell fate in mice. Dev Cell (2010) 1.64
Sox18 and Sox7 play redundant roles in vascular development. Blood (2007) 1.60
Seeds of concern. Nature (2004) 1.57
Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol (2005) 1.55
Sry: the master switch in mammalian sex determination. Development (2010) 1.52
SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. J Biol Chem (2007) 1.42
SoxF genes: Key players in the development of the cardio-vascular system. Int J Biochem Cell Biol (2009) 1.41
Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary. Mol Reprod Dev (2004) 1.38
Endothelial cell migration directs testis cord formation. Dev Biol (2008) 1.35
The makings of maleness: towards an integrated view of male sexual development. Nat Rev Genet (2006) 1.35
Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis. PLoS One (2011) 1.32
SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro. J Biol Chem (2003) 1.28
Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development. Endocrinology (2003) 1.28
Mouse germ cell development: from specification to sex determination. Mol Cell Endocrinol (2009) 1.24
Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y(DOM) sex reversal. Dev Biol (2005) 1.24
Sry and the hesitant beginnings of male development. Dev Biol (2006) 1.22
Initiating meiosis: the case for retinoic acid. Biol Reprod (2012) 1.17
A critical time window of Sry action in gonadal sex determination in mice. Development (2008) 1.14
Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol (2008) 1.13
Building the mammalian testis: origins, differentiation, and assembly of the component cell populations. Genes Dev (2013) 1.13
In situ hybridization of whole-mount embryos. Methods Mol Biol (2006) 1.13
Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice. Development (2009) 1.13
Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a. Science (2013) 1.11
Sox18 mutations in the ragged mouse alleles ragged-like and opossum. Genesis (2003) 1.11
Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development. Hum Mol Genet (2009) 1.11
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
Sex determination in mammalian germ cells: extrinsic versus intrinsic factors. Reproduction (2010) 1.10
Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res (2002) 1.09
Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice. Dev Biol (2011) 1.08
Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice. Mech Dev (2009) 1.05
Identification of novel markers of mouse fetal ovary development. PLoS One (2012) 1.03
The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem (2004) 1.02
SOX9 regulates microRNA miR-202-5p/3p expression during mouse testis differentiation. Biol Reprod (2013) 1.02
Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid. BMC Dev Biol (2008) 1.02
Control of mammalian germ cell entry into meiosis. Mol Cell Endocrinol (2013) 1.01
Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn (2009) 1.01
Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development. J Natl Cancer Inst (2006) 1.00
Conserved regulatory modules in the Sox9 testis-specific enhancer predict roles for SOX, TCF/LEF, Forkhead, DMRT, and GATA proteins in vertebrate sex determination. Int J Biochem Cell Biol (2009) 0.98
Genomic screen for genes involved in mammalian craniofacial development. Genesis (2003) 0.97
Tumor lymphangiogenesis as a potential therapeutic target. J Oncol (2012) 0.97
A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development. Eur J Hum Genet (2011) 0.97
Expression of the tudor-related gene Tdrd5 during development of the male germline in mice. Gene Expr Patterns (2004) 0.95
FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology (2010) 0.95
Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod (2009) 0.95
Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice. Biol Reprod (2012) 0.94
Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development (2012) 0.94
The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development. Biol Reprod (2008) 0.93
Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis. Reproduction (2005) 0.93
Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet (2011) 0.92
The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18. J Biol Chem (2003) 0.92
CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary. Dev Biol (2006) 0.92
Up-regulation of SOX9 in human sex-determining region on the Y chromosome (SRY)-negative XX males. Clin Endocrinol (Oxf) (2007) 0.91
Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Res (2012) 0.90
The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice. Biol Reprod (2009) 0.90
Male sex determination: insights into molecular mechanisms. Asian J Androl (2011) 0.89
Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice. FASEB J (2011) 0.89
SRY protein function in sex determination: thinking outside the box. Chromosome Res (2012) 0.88
The molecular genetics of sex determination and sex reversal in mammals. Semin Reprod Med (2012) 0.87
HMG box transcription factor gene Hbp1 is expressed in germ cells of the developing mouse testis. Dev Dyn (2004) 0.87
Cbx2, a polycomb group gene, is required for Sry gene expression in mice. Endocrinology (2011) 0.87
Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: implications for retinoid balance in gonad development. Dev Dyn (2009) 0.87
Uncovering gene regulatory networks during mouse fetal germ cell development. Biol Reprod (2010) 0.86
VEGFD regulates blood vascular development by modulating SOX18 activity. Blood (2013) 0.86
Wnt signaling in ovarian development inhibits Sf1 activation of Sox9 via the Tesco enhancer. Endocrinology (2011) 0.86
Regulation of germ cell meiosis in the fetal ovary. Int J Dev Biol (2012) 0.86
A cell-autonomous role for WT1 in regulating Sry in vivo. Hum Mol Genet (2009) 0.85
Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation. Reproduction (2007) 0.85
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish. J Biol Chem (2011) 0.84
Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary. PLoS One (2012) 0.84
Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development. Dev Dyn (2005) 0.84
Extensive vascularization of developing mouse ovaries revealed by caveolin-1 expression. Dev Dyn (2002) 0.84
Charting the course of ovarian development in vertebrates. Int J Dev Biol (2002) 0.84
Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. J Biol Chem (2012) 0.83
Global survey of protein expression during gonadal sex determination in mice. Mol Cell Proteomics (2009) 0.83
Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation. Int J Dev Biol (2010) 0.83
Sox8 is expressed at similar levels in gonads of both sexes during the sex determining period in turtles. Dev Dyn (2004) 0.83
Functional analysis of the SRY-KRAB interaction in mouse sex determination. Biol Cell (2009) 0.83
FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J (2014) 0.82
A male-specific role for p38 mitogen-activated protein kinase in germ cell sex differentiation in mice. Biol Reprod (2010) 0.81
Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors. Int J Dev Biol (2013) 0.81
Sox8 and Sertoli-cell function. Ann N Y Acad Sci (2007) 0.80
Cell cycle analysis of fetal germ cells during sex differentiation in mice. Biol Cell (2009) 0.80
Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival. PLoS One (2011) 0.80
Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis. Dev Dyn (2009) 0.80
Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Hum Mol Genet (2009) 0.80
Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression. Biol Reprod (2014) 0.79
Comparative proteomic analysis to study molecular events during gonad development in mice. Genesis (2006) 0.79
Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. PLoS One (2012) 0.79
New insights into SRY regulation through identification of 5' conserved sequences. BMC Mol Biol (2008) 0.79