Published in J Cell Sci on August 08, 2006
Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell (2007) 4.18
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell (2009) 3.31
Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. Int J Biochem Cell Biol (2007) 2.78
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell (2014) 2.62
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev (2010) 2.50
Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium. Am J Physiol Gastrointest Liver Physiol (2009) 2.21
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res (2008) 2.16
Susceptibility loci for intracranial aneurysm in European and Japanese populations. Nat Genet (2008) 1.90
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity. Cell (2012) 1.54
Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells (2009) 1.43
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. Cell Metab (2011) 1.43
Transcriptional programs controlling perinatal lung maturation. PLoS One (2012) 1.41
The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease. Trends Mol Med (2010) 1.38
Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors. Genes Dev (2011) 1.36
The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17. Dev Biol (2010) 1.34
CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One (2012) 1.33
The Yin and Yang of Sox proteins: Activation and repression in development and disease. J Neurosci Res (2009) 1.20
Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells. Development (2010) 1.17
Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma. PLoS One (2011) 1.16
Specification of arterial, venous, and lymphatic endothelial cells during embryonic development. Histol Histopathol (2010) 1.12
Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Commun (2013) 1.12
An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics (2013) 1.11
Genetic targeting of the endoderm with claudin-6CreER. Dev Dyn (2008) 1.11
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium. PLoS One (2009) 1.10
SRY-box containing gene 17 regulates the Wnt/β-catenin signaling pathway in oligodendrocyte progenitor cells. J Neurosci (2011) 1.10
Transcriptional regulation of endothelial cell and vascular development. Circ Res (2013) 1.03
Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1. Hum Mol Genet (2012) 1.02
Inferring the transcriptional landscape of bovine skeletal muscle by integrating co-expression networks. PLoS One (2009) 1.01
Tumor lymphangiogenesis as a potential therapeutic target. J Oncol (2012) 0.97
Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice. J Clin Invest (2012) 0.96
Sox17 haploinsufficiency results in perinatal biliary atresia and hepatitis in C57BL/6 background mice. Development (2013) 0.92
Cyclical and patch-like GDNF distribution along the basal surface of Sertoli cells in mouse and hamster testes. PLoS One (2011) 0.91
Intrinsic and extrinsic modifiers of the regulative capacity of the developing liver. Mech Dev (2012) 0.90
Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters. Mol Cell Biol (2014) 0.90
RNA-seq analysis of the functional compartments within the rat placentation site. Endocrinology (2012) 0.89
Sry-box (Sox) transcription factors in gastrointestinal physiology and disease. Am J Physiol Gastrointest Liver Physiol (2011) 0.89
Common binding by redundant group B Sox proteins is evolutionarily conserved in Drosophila. BMC Genomics (2015) 0.87
Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation. Cancer Lett (2013) 0.85
Antenatal maternal long-term hypoxia: acclimatization responses with altered gene expression in ovine fetal carotid arteries. PLoS One (2013) 0.85
Sox7 is regulated by ETV2 during cardiovascular development. Stem Cells Dev (2014) 0.84
The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD). Curr Hypertens Rev (2013) 0.84
Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina. PLoS One (2015) 0.83
Transciptome analysis of the gill and swimbladder of Takifugu rubripes by RNA-Seq. PLoS One (2014) 0.83
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. Elife (2017) 0.83
Early growth response protein 1 acts as an activator of SOX18 promoter. Exp Mol Med (2010) 0.82
The role of Sox genes in lung morphogenesis and cancer. Int J Mol Sci (2012) 0.81
The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells. PLoS One (2012) 0.81
Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation. Sci Rep (2016) 0.81
Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain. J Neurol Neurosurg Psychiatry (2014) 0.80
Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. PLoS One (2012) 0.79
Sox17 is required for normal pulmonary vascular morphogenesis. Dev Biol (2014) 0.78
Sox17 regulates insulin secretion in the normal and pathologic mouse β cell. PLoS One (2014) 0.77
Concise review: programming human pluripotent stem cells into blood. Br J Haematol (2016) 0.77
Sox17 regulates liver lipid metabolism and adaptation to fasting. PLoS One (2014) 0.77
SOX18 Is a Novel Target Gene of Hedgehog Signaling in Cervical Carcinoma Cell Lines. PLoS One (2015) 0.77
Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach. Mamm Genome (2010) 0.76
Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas. Semin Cell Dev Biol (2016) 0.76
Development of the kidney medulla. Organogenesis (2012) 0.76
Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation. Nucleic Acids Res (2017) 0.75
Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development. Clin Epigenetics (2016) 0.75
Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol (2015) 0.75
Fate mapping of gallbladder progenitors in posteroventral foregut endoderm of mouse early somite-stage embryos. J Vet Med Sci (2015) 0.75
SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development. Mech Dev (2017) 0.75
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell (2013) 13.37
Retracted Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science (2004) 7.21
Retinoid signaling determines germ cell fate in mice. Science (2006) 4.17
Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (2002) 4.13
Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell (2002) 3.39
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab (2006) 3.34
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest (2008) 3.25
Sox18 induces development of the lymphatic vasculature in mice. Nature (2008) 2.91
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat Med (2002) 2.61
Sex determination and gonadal development in mammals. Physiol Rev (2007) 2.60
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat Med (2004) 2.51
Role of Krüppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis. J Biol Chem (2005) 2.45
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature (2012) 2.38
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science (2010) 2.34
Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity. Proc Natl Acad Sci U S A (2005) 2.31
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opin Genet Dev (2002) 2.24
PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. J Clin Invest (2003) 2.23
Expression of distinct RNAs from 3' untranslated regions. Nucleic Acids Res (2010) 2.08
Genesis and expansion of metazoan transcription factor gene classes. Mol Biol Evol (2008) 2.01
Retinoic acid, meiosis and germ cell fate in mammals. Development (2007) 1.91
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone (2005) 1.68
Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos. Biochem Biophys Res Commun (2007) 1.68
Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis. J Cell Biol (2007) 1.67
FGF9 suppresses meiosis and promotes male germ cell fate in mice. Dev Cell (2010) 1.64
Testis tissue explantation cures spermatogenic failure in c-Kit ligand mutant mice. Proc Natl Acad Sci U S A (2012) 1.63
Sox18 and Sox7 play redundant roles in vascular development. Blood (2007) 1.60
Identification of Sox17 as a transcription factor that regulates oligodendrocyte development. J Neurosci (2006) 1.59
Seeds of concern. Nature (2004) 1.57
Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol (2005) 1.55
Sry: the master switch in mammalian sex determination. Development (2010) 1.52
In vitro production of fertile sperm from murine spermatogonial stem cell lines. Nat Commun (2011) 1.49
Retraction. Science (2007) 1.48
Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Biol Pharm Bull (2008) 1.42
SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. J Biol Chem (2007) 1.42
Skp2 controls adipocyte proliferation during the development of obesity. J Biol Chem (2006) 1.41
SoxF genes: Key players in the development of the cardio-vascular system. Int J Biochem Cell Biol (2009) 1.41
Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary. Mol Reprod Dev (2004) 1.38
Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J Biol Chem (2010) 1.37
Early endoderm development in vertebrates: lineage differentiation and morphogenetic function. Curr Opin Genet Dev (2003) 1.35
Endothelial cell migration directs testis cord formation. Dev Biol (2008) 1.35
The makings of maleness: towards an integrated view of male sexual development. Nat Rev Genet (2006) 1.35
Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes. Hum Mol Genet (2006) 1.33
Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis. PLoS One (2011) 1.32
SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro. J Biol Chem (2003) 1.28
Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development. Endocrinology (2003) 1.28
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation. Nat Med (2008) 1.27
The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity. J Clin Invest (2008) 1.26
Mouse germ cell development: from specification to sex determination. Mol Cell Endocrinol (2009) 1.24
Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y(DOM) sex reversal. Dev Biol (2005) 1.24
Sry and the hesitant beginnings of male development. Dev Biol (2006) 1.22
Outer membrane vesicles of Helicobacter pylori TK1402 are involved in biofilm formation. BMC Microbiol (2009) 1.22
Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats. Glycobiology (2006) 1.20
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis. Pflugers Arch (2004) 1.19
Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells. Proc Natl Acad Sci U S A (2007) 1.19
Sox17 plays a substantial role in late-stage differentiation of the extraembryonic endoderm in vitro. J Cell Sci (2007) 1.18
Initiating meiosis: the case for retinoic acid. Biol Reprod (2012) 1.17
Role of KLF15 in regulation of hepatic gluconeogenesis and metformin action. Diabetes (2010) 1.14
A critical time window of Sry action in gonadal sex determination in mice. Development (2008) 1.14
Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol (2008) 1.13
Building the mammalian testis: origins, differentiation, and assembly of the component cell populations. Genes Dev (2013) 1.13
In situ hybridization of whole-mount embryos. Methods Mol Biol (2006) 1.13
Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice. Development (2009) 1.13
Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol (2006) 1.12
Sox18 mutations in the ragged mouse alleles ragged-like and opossum. Genesis (2003) 1.11
Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a. Science (2013) 1.11
Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development. Hum Mol Genet (2009) 1.11
Production of Sry knockout mouse using TALEN via oocyte injection. Sci Rep (2013) 1.11
Sex determination in mammalian germ cells: extrinsic versus intrinsic factors. Reproduction (2010) 1.10
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS One (2010) 1.10
Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res (2002) 1.09
Identification and characterization of an alternative promoter of the human PGC-1alpha gene. Biochem Biophys Res Commun (2009) 1.09
Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice. Dev Biol (2011) 1.08
Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling. Cell Metab (2011) 1.06
Proteomic analysis of two types of exosomes in human whole saliva. Biol Pharm Bull (2011) 1.06
Targeted gene deletion of miRNAs in mice by TALEN system. PLoS One (2013) 1.06
CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis. Nat Med (2012) 1.06
Role of Krüppel-like factor 15 in PEPCK gene expression in the liver. Biochem Biophys Res Commun (2005) 1.05
Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis. Dev Biol (2009) 1.05