Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling.

PubWeight™: 2.48‹?› | Rank: Top 2%

🔗 View Article (PMID 16402904)

Published in Annu Rev Pharmacol Toxicol on January 01, 2006

Authors

Jason M Hansen1, Young-Mi Go, Dean P Jones

Author Affiliations

1: Department of Medicine and Clinical Biomarkers Laboratory, Division of Pulmonary Medicine, Emory University, Atlanta, GA 30322, USA. jhansen@emory.edu

Articles citing this

(truncated to the top 100)

Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med (2010) 5.76

Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev (2008) 5.74

Radical-free biology of oxidative stress. Am J Physiol Cell Physiol (2008) 4.33

Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. Cell (2007) 3.54

Mitochondrial energetics and therapeutics. Annu Rev Pathol (2010) 3.07

Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med (2007) 2.47

Oxidative stress resistance in Deinococcus radiodurans. Microbiol Mol Biol Rev (2011) 2.43

Redox compartmentalization in eukaryotic cells. Biochim Biophys Acta (2008) 2.35

Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal (2009) 2.17

Energetics, epigenetics, mitochondrial genetics. Mitochondrion (2009) 2.08

Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev (2014) 1.96

Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J (2009) 1.89

The pathophysiology of mitochondrial disease as modeled in the mouse. Genes Dev (2009) 1.87

PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria. Exp Cell Res (2008) 1.64

Mitochondria as chi. Genetics (2008) 1.53

Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol (2007) 1.52

Real-time monitoring of oxidative stress in live mouse skin. J Invest Dermatol (2013) 1.48

Glutathione and apoptosis. Free Radic Res (2008) 1.48

A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal (2010) 1.38

ROS-dependent signal transduction. Curr Opin Cell Biol (2014) 1.37

Hydrogen peroxide probes directed to different cellular compartments. PLoS One (2011) 1.34

Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One (2009) 1.30

Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach. Mol Cell Proteomics (2010) 1.26

Redox sensing: orthogonal control in cell cycle and apoptosis signalling. J Intern Med (2010) 1.24

Cysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular system. Circ Res (2013) 1.19

Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells. Free Radic Biol Med (2006) 1.19

Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity. FASEB J (2011) 1.16

Diverse subcellular locations of cryptogein-induced reactive oxygen species production in tobacco Bright Yellow-2 cells. Plant Physiol (2007) 1.15

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases. Recent Pat CNS Drug Discov (2012) 1.13

Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial complex II in the post-ischemic myocardium. J Biol Chem (2008) 1.12

Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kappaB activities. Free Radic Biol Med (2007) 1.11

Evolution of the mitochondrial genome in mammals living at high altitude: new insights from a study of the tribe Caprini (Bovidae, Antilopinae). J Mol Evol (2009) 1.09

Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. Toxicol Sci (2009) 1.08

Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma. Am J Physiol Regul Integr Comp Physiol (2009) 1.08

The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. PLoS One (2009) 1.06

Regulatory control or oxidative damage? Proteomic approaches to interrogate the role of cysteine oxidation status in biological processes. Mol Cell Proteomics (2011) 1.05

Activation of the lifespan regulator p66Shc through reversible disulfide bond formation. Proc Natl Acad Sci U S A (2008) 1.05

Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2012) 1.01

Dehydration, rehydration, and overhydration alter patterns of gene expression in the Antarctic midge, Belgica antarctica. J Comp Physiol B (2009) 1.00

In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: relevance to Alzheimer's disease and other oxidative stress-related neurodegenerative disorders. Free Radic Biol Med (2006) 1.00

Thioredoxin 1 as a subcellular biomarker of redox imbalance in human prostate cancer progression. Free Radic Biol Med (2010) 0.99

Kinetic analysis of intracellular concentrations of reactive nitrogen species. Chem Res Toxicol (2008) 0.99

Intestinal redox biology and oxidative stress. Semin Cell Dev Biol (2012) 0.99

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice. J Gerontol A Biol Sci Med Sci (2011) 0.99

Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1. J Pharmacol Exp Ther (2010) 0.98

Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal (2012) 0.97

Chemical approaches to detect and analyze protein sulfenic acids. Mass Spectrom Rev (2013) 0.96

Mitochondria and redox signaling in steatohepatitis. Antioxid Redox Signal (2011) 0.96

Lipid metabolism and body composition in Gclm(-/-) mice. Toxicol Appl Pharmacol (2011) 0.95

Protein thiyl radical mediates S-glutathionylation of complex I. Free Radic Biol Med (2012) 0.94

Redox-sensitive YFP sensors monitor dynamic nuclear and cytosolic glutathione redox changes. Free Radic Biol Med (2012) 0.94

Peroxynitrite-mediated oxidative modifications of complex II: relevance in myocardial infarction. Biochemistry (2010) 0.93

Nuclear damages and oxidative stress: new perspectives for laminopathies. Eur J Histochem (2012) 0.93

Redox biology of the intestine. Free Radic Res (2011) 0.92

Mrp1 localization and function in cardiac mitochondria after doxorubicin. Mol Pharmacol (2009) 0.91

Molecular mechanisms underlying chemical liver injury. Expert Rev Mol Med (2012) 0.91

Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis. Neurochem Res (2009) 0.91

Heat-shock response protects peripheral blood mononuclear cells (PBMCs) from hydrogen peroxide-induced mitochondrial disturbance. Cell Stress Chaperones (2008) 0.91

Chemical composition, antioxidant, antimicrobial and cytotoxic activities of Tagetes minuta and Ocimum basilicum essential oils. Food Sci Nutr (2014) 0.90

Glutathione in cerebral microvascular endothelial biology and pathobiology: implications for brain homeostasis. Int J Cell Biol (2012) 0.89

Increasing discordant antioxidant protein levels and enzymatic activities contribute to increasing redox imbalance observed during human prostate cancer progression. Free Radic Biol Med (2013) 0.89

The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells. Toxicology (2008) 0.89

The epigenome and the mitochondrion: bioenergetics and the environment [corrected]. Genes Dev (2010) 0.89

Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo. Free Radic Biol Med (2013) 0.89

The effects of hexavalent chromium on thioredoxin reductase and peroxiredoxins in human bronchial epithelial cells. Free Radic Biol Med (2009) 0.89

Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells. Toxicology (2008) 0.88

Benzofurazan sulfides for thiol imaging and quantification in live cells through fluorescence microscopy. Anal Chem (2012) 0.88

Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease. Antioxid Redox Signal (2012) 0.87

Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow. Integr Biol (Camb) (2010) 0.87

The effects of acrolein on the thioredoxin system: implications for redox-sensitive signaling. Mol Nutr Food Res (2011) 0.86

Annexin A2: the importance of being redox sensitive. Int J Mol Sci (2013) 0.86

Current status of NADPH oxidase research in cardiovascular pharmacology. Vasc Health Risk Manag (2013) 0.85

The pro-oxidant chromium(VI) inhibits mitochondrial complex I, complex II, and aconitase in the bronchial epithelium: EPR markers for Fe-S proteins. Free Radic Biol Med (2010) 0.84

Genome-wide transcriptional analysis of genes associated with acute desiccation stress in Anopheles gambiae. PLoS One (2011) 0.84

Enzyme activity of phosphatase of regenerating liver is controlled by the redox environment and its C-terminal residues. Biochemistry (2009) 0.84

Reduction of mitochondrial protein mitoNEET [2Fe-2S] clusters by human glutathione reductase. Free Radic Biol Med (2015) 0.83

HIV-1, reactive oxygen species, and vascular complications. Free Radic Biol Med (2012) 0.83

Conformational changes in redox pairs of protein structures. Protein Sci (2009) 0.83

Rapid and thiol-specific high-throughput assay for simultaneous relative quantification of total thiols, protein thiols, and nonprotein thiols in cells. Anal Chem (2014) 0.82

Acrolein oxidizes the cytosolic and mitochondrial thioredoxins in human endothelial cells. Toxicology (2007) 0.82

Conserved hydrogen bonding networks of MitoNEET tune Fe-S cluster binding and structural stability. Biochemistry (2013) 0.82

Mass spectrometry profiles superoxide-induced intramolecular disulfide in the FMN-binding subunit of mitochondrial Complex I. J Am Soc Mass Spectrom (2008) 0.82

The intracellular redox stress caused by hexavalent chromium is selective for proteins that have key roles in cell survival and thiol redox control. Toxicology (2011) 0.82

The effects of chromium(VI) on the thioredoxin system: implications for redox regulation. Free Radic Biol Med (2012) 0.81

Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes. Redox Biol (2014) 0.81

Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio). Free Radic Biol Med (2015) 0.81

In vitro susceptibility of thioredoxins and glutathione to redox modification and aging-related changes in skeletal muscle. Free Radic Biol Med (2012) 0.81

The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin. PLoS One (2014) 0.81

The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes. Hum Mol Genet (2013) 0.81

A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors. Clin Transl Med (2016) 0.81

Two zinc-cluster transcription factors control induction of alternative oxidase in Neurospora crassa. Genetics (2007) 0.80

Gender-specific cytokine pathways, targets, and biomarkers for the switch from health to adenoma and colorectal cancer. Clin Dev Immunol (2011) 0.80

The discovery of how gender influences age immunological mechanisms in health and disease, and the identification of ageing gender-specific biomarkers, could lead to specifically tailored treatment and ultimately improve therapeutic success rates. Immun Ageing (2012) 0.80

Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae. BMC Syst Biol (2009) 0.80

Critical role of mitochondrial ROS is dependent on their site of production on the electron transport chain in ischemic heart. Am J Cardiovasc Dis (2016) 0.79

Inhibition of glutathione synthesis distinctly alters mitochondrial and cytosolic redox poise. Exp Biol Med (Maywood) (2014) 0.79

Ageing gender-specific "Biomarkers of Homeostasis", to protect ourselves against the diseases of the old age. Immun Ageing (2014) 0.79

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms. PLoS One (2015) 0.79

Anti-inflammatory Effect of Oyster Shell Extract in LPS-stimulated Raw 264.7 Cells. Prev Nutr Food Sci (2013) 0.79

Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress. Eur J Clin Nutr (2015) 0.78

Articles by these authors

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature (2004) 5.85

Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med (2007) 2.47

Extracellular thiols and thiol/disulfide redox in metabolism. Annu Rev Nutr (2004) 2.41

Redox compartmentalization in eukaryotic cells. Biochim Biophys Acta (2008) 2.35

Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight-loss surgery. Obesity (Silver Spring) (2008) 2.23

Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem (2003) 2.14

Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1. Toxicol Sci (2004) 2.12

Association between novel oxidative stress markers and C-reactive protein among adults without clinical coronary heart disease. Atherosclerosis (2005) 2.02

apLCMS--adaptive processing of high-resolution LC/MS data. Bioinformatics (2009) 1.98

Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control. FASEB J (2004) 1.97

Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function. Annu Rev Nutr (2003) 1.93

Intracellular proatherogenic events and cell adhesion modulated by extracellular thiol/disulfide redox state. Circulation (2005) 1.90

Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J (2007) 1.86

Oxidation of glutathione and cysteine in human plasma associated with smoking. Free Radic Biol Med (2003) 1.82

Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling. Biochem J (2005) 1.78

Oxidative stress markers are associated with persistent atrial fibrillation. Clin Chem (2007) 1.72

Diurnal variation in glutathione and cysteine redox states in human plasma. Am J Clin Nutr (2007) 1.66

The role of plasma aminothiols in the prediction of coronary microvascular dysfunction and plaque vulnerability. Atherosclerosis (2011) 1.62

xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data. BMC Bioinformatics (2013) 1.61

The relationship between plasma levels of oxidized and reduced thiols and early atherosclerosis in healthy adults. J Am Coll Cardiol (2006) 1.59

Statin therapy for the prevention of atrial fibrillation trial (SToP AF trial). J Cardiovasc Electrophysiol (2010) 1.57

Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome? JPEN J Parenter Enteral Nutr (2007) 1.55

Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line. Free Radic Biol Med (2002) 1.51

Thioredoxin and its role in toxicology. Toxicol Sci (2003) 1.48

The redox proteome. J Biol Chem (2013) 1.48

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism. Anticancer Drugs (2005) 1.48

Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arterioscler Thromb Vasc Biol (2007) 1.47

Oxidant-induced apoptosis in human retinal pigment epithelial cells: dependence on extracellular redox state. Invest Ophthalmol Vis Sci (2005) 1.47

Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J Biol Chem (2002) 1.46

The role of the multidrug resistance protein-1 in modulation of endothelial cell oxidative stress. Circ Res (2005) 1.46

Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions. Free Radic Biol Med (2005) 1.44

Predicting network activity from high throughput metabolomics. PLoS Comput Biol (2013) 1.44

Dietary supplementation with orotate and uracil increases adaptive growth of jejunal mucosa after massive small bowel resection in rats. JPEN J Parenter Enteral Nutr (2005) 1.43

Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis. Toxicol Sci (2006) 1.43

Metabolic effects of albumin therapy in acute lung injury measured by proton nuclear magnetic resonance spectroscopy of plasma: a pilot study. Crit Care Med (2011) 1.42

Cysteine/cystine redox signaling in cardiovascular disease. Free Radic Biol Med (2010) 1.42

A practical approach to detect unique metabolic patterns for personalized medicine. Analyst (2010) 1.41

Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. Am J Physiol Gastrointest Liver Physiol (2002) 1.40

Prohibitin protects against oxidative stress in intestinal epithelial cells. FASEB J (2006) 1.39

A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal (2010) 1.38

Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol (2007) 1.34

Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress. Arch Biochem Biophys (2007) 1.33

Association between adherence to the Mediterranean diet and oxidative stress. Am J Clin Nutr (2008) 1.32

Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation. Proc Natl Acad Sci U S A (2007) 1.31

A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential. Free Radic Biol Med (2009) 1.31

Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One (2009) 1.30

Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol (2011) 1.30

Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells. FASEB J (2002) 1.30

Oxidation of nuclear thioredoxin during oxidative stress. FEBS Lett (2003) 1.27

Redox control systems in the nucleus: mechanisms and functions. Antioxid Redox Signal (2010) 1.25

Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system. Exp Neurol (2007) 1.24

Clinical trials of antioxidants as cancer prevention agents: past, present, and future. Free Radic Biol Med (2011) 1.23

Oxidative stress is associated with impaired arterial elasticity. Atherosclerosis (2011) 1.23

Detectable serum flagellin and lipopolysaccharide and upregulated anti-flagellin and lipopolysaccharide immunoglobulins in human short bowel syndrome. Am J Physiol Regul Integr Comp Physiol (2007) 1.23

Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2. Hypertension (2009) 1.23

Mitochondrial thioredoxin in regulation of oxidant-induced cell death. FEBS Lett (2006) 1.22

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol (2012) 1.22

Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling. Am J Physiol Gastrointest Liver Physiol (2005) 1.21

Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion. Am J Pathol (2007) 1.21

Inhibition of influenza infection by glutathione. Free Radic Biol Med (2003) 1.20

Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells. Free Radic Biol Med (2006) 1.19

Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 1.18

Reactive species and mitochondrial dysfunction: mechanistic significance of 4-hydroxynonenal. Environ Mol Mutagen (2010) 1.17

A rapid LC-FTMS method for the analysis of cysteine, cystine and cysteine/cystine steady-state redox potential in human plasma. Clin Chim Acta (2008) 1.16

Endothelial function and aminothiol biomarkers of oxidative stress in healthy adults. Hypertension (2008) 1.15

Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice. Gastroenterology (2009) 1.15

The nature of nurture: refining the definition of the exposome. Toxicol Sci (2013) 1.14

Quantification of redox conditions in the nucleus. Methods Mol Biol (2009) 1.13

Oxidative stress modulates PPAR gamma in vascular endothelial cells. Free Radic Biol Med (2010) 1.13

Thiol/disulfide redox states in signaling and sensing. Crit Rev Biochem Mol Biol (2013) 1.13

Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorectal adenoma patients: a randomized, controlled clinical trial. Cancer Prev Res (Phila) (2011) 1.13

Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione. Am J Physiol Regul Integr Comp Physiol (2007) 1.12

Oxidation of plasma cysteine/cystine redox state in endotoxin-induced lung injury. Am J Respir Cell Mol Biol (2008) 1.11

Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kappaB activities. Free Radic Biol Med (2007) 1.11

Glutamine and KGF each regulate extracellular thiol/disulfide redox and enhance proliferation in Caco-2 cells. Am J Physiol Regul Integr Comp Physiol (2003) 1.11

A network perspective on metabolism and aging. Integr Comp Biol (2010) 1.10

Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation. Toxicol Sci (2006) 1.10

H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione or thioredoxin-1. J Biol Chem (2003) 1.09

Mapping the cysteine proteome: analysis of redox-sensing thiols. Curr Opin Chem Biol (2011) 1.09

Metabolome-wide association study of neovascular age-related macular degeneration. PLoS One (2013) 1.09

Current thoughts on the role of mitochondria and free radicals in the biology of aging. J Gerontol A Biol Sci Med Sci (2009) 1.08

Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma. Am J Physiol Regul Integr Comp Physiol (2009) 1.08

Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration. Am J Ophthalmol (2005) 1.08

High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring. Toxicology (2012) 1.08

Thiol/disulfide redox status is oxidized in plasma and small intestinal and colonic mucosa of rats with inadequate sulfur amino acid intake. J Nutr (2006) 1.08

Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in critically ill surgical patients. JPEN J Parenter Enteral Nutr (2008) 1.07

Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia. Dis Model Mech (2012) 1.07

Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains. FASEB J (2004) 1.06

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction. AIDS Res Ther (2009) 1.05

Identification of thioredoxin-2 as a regulator of the mitochondrial permeability transition. Toxicol Sci (2008) 1.04

Discovery of metabolite features for the modelling and analysis of high-resolution NMR spectra. Int J Data Min Bioinform (2008) 1.04

Protein Cysteines Map to Functional Networks According to Steady-state Level of Oxidation. J Proteomics Bioinform (2011) 1.04

Integrated redox proteomics and metabolomics of mitochondria to identify mechanisms of cd toxicity. Toxicol Sci (2014) 1.03

Trefoil peptide expression and goblet cell number in rat intestine: effects of KGF and fasting-refeeding. Am J Physiol Regul Integr Comp Physiol (2002) 1.02