Published in J Neurosci on January 11, 2006
The hormonal control of food intake. Cell (2007) 3.61
Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways. Gastroenterology (2012) 1.58
Central effects of estradiol in the regulation of food intake, body weight, and adiposity. J Steroid Biochem Mol Biol (2009) 1.33
Neuronal control of energy homeostasis. FEBS Lett (2007) 1.13
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2. Nature (2009) 1.10
Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar. Elife (2013) 1.01
Estradiol signaling in the regulation of reproduction and energy balance. Front Neuroendocrinol (2012) 0.99
Ablation of neurons expressing melanin-concentrating hormone (MCH) in adult mice improves glucose tolerance independent of MCH signaling. J Neurosci (2013) 0.97
The role of hypothalamic estrogen receptors in metabolic regulation. Front Neuroendocrinol (2014) 0.93
Animals models of MCH function and what they can tell us about its role in energy balance. Peptides (2009) 0.93
Lateral hypothalamic circuits for feeding and reward. Nat Neurosci (2016) 0.92
Neurochemical characterization of neurons expressing melanin-concentrating hormone receptor 1 in the mouse hypothalamus. J Comp Neurol (2013) 0.91
Neurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleep. Front Syst Neurosci (2015) 0.89
Mechanism of the anti-obesity effects induced by a novel melanin-concentrating hormone 1-receptor antagonist in mice. Br J Pharmacol (2009) 0.89
The role of melanin-concentrating hormone and its receptors in energy homeostasis. Front Endocrinol (Lausanne) (2013) 0.86
Hyperphagia and obesity produced by arcuate injection of NPY-saporin do not require upregulation of lateral hypothalamic orexigenic peptide genes. Peptides (2008) 0.86
Melanin-concentrating hormone: a new sleep factor? Front Neurol (2011) 0.86
Molecular annotation of integrative feeding neural circuits. Cell Metab (2011) 0.85
Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. PLoS One (2011) 0.85
GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. J Neurosci (2015) 0.82
Melanin concentrating hormone and estrogen receptor-alpha are coexstensive but not coexpressed in cells of male rat hypothalamus. Neurosci Lett (2007) 0.82
Melanin-concentrating hormone neurons specifically promote rapid eye movement sleep in mice. Neuroscience (2016) 0.81
Expression of melanin-concentrating hormone receptor 2 protects against diet-induced obesity in male mice. Endocrinology (2013) 0.80
Meta-analysis of melanin-concentrating hormone signaling-deficient mice on behavioral and metabolic phenotypes. PLoS One (2014) 0.79
Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour. J Physiol (2016) 0.79
Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons. Diabetes (2014) 0.79
The use of animal models to decipher physiological and neurobiological alterations of anorexia nervosa patients. Front Endocrinol (Lausanne) (2015) 0.77
Two naturally occurring mutations in the type 1 melanin-concentrating hormone receptor abolish agonist-induced signaling. J Pharmacol Exp Ther (2010) 0.76
Computational Analysis of the Hypothalamic Control of Food Intake. Front Comput Neurosci (2016) 0.76
Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters. Physiol Behav (2011) 0.76
Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice. Eur Neuropsychopharmacol (2015) 0.75
Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone-induced liver damage through inflammation and endoplasmic reticulum stress. Hepatology (2016) 0.75
Regulated Control of Melanin-Concentrating Hormone Receptor 1 through Posttranslational Modifications. Front Endocrinol (Lausanne) (2013) 0.75
The role of melanin concentrating hormone (MCH) in the central chemoreflex: a knockdown study by siRNA in the lateral hypothalamus in rats. PLoS One (2014) 0.75
The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors. Front Syst Neurosci (2017) 0.75
Lef1-dependent hypothalamic neurogenesis inhibits anxiety. PLoS Biol (2017) 0.75
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell (2006) 8.46
Identification of white adipocyte progenitor cells in vivo. Cell (2008) 6.58
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron (2003) 6.05
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci U S A (2002) 6.00
Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science (2004) 5.98
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (2002) 5.89
Whole population, genome-wide mapping of hidden relatedness. Genome Res (2008) 4.72
Abnormal osmotic regulation in trpv4-/- mice. Proc Natl Acad Sci U S A (2003) 3.87
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature (2004) 3.29
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature (2012) 3.15
Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. J Neurosci (2003) 3.08
Leptin targets in the mouse brain. J Comp Neurol (2009) 2.80
Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2003) 2.50
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci U S A (2004) 2.48
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metab (2007) 2.48
Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metab (2005) 2.29
Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci (2005) 2.29
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res (2003) 2.27
Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell (2012) 2.22
Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron (2006) 2.16
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science (2012) 2.14
Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia. Nat Genet (2006) 2.07
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. PLoS Genet (2009) 2.02
Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. Heart Rhythm (2009) 1.91
Antidiabetic effects of IGFBP2, a leptin-regulated gene. Cell Metab (2010) 1.85
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. Biochem Biophys Res Commun (2008) 1.74
Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. J Clin Invest (2004) 1.71
Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice. Neuron (2004) 1.65
Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. Arterioscler Thromb Vasc Biol (2008) 1.63
Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. Cell Metab (2007) 1.63
DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. Am J Hum Genet (2011) 1.62
Hyperleptinemia is required for the development of leptin resistance. PLoS One (2010) 1.55
Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically. Proc Natl Acad Sci U S A (2010) 1.51
Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Biochem J (2003) 1.49
Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. Proc Natl Acad Sci U S A (2006) 1.48
PET imaging of leptin biodistribution and metabolism in rodents and primates. Cell Metab (2009) 1.47
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. J Biol Chem (2005) 1.46
Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J Physiol Endocrinol Metab (2004) 1.44
Obesity: Causes and control of excess body fat. Nature (2009) 1.39
Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development (2011) 1.36
Mediator MED23 links insulin signaling to the adipogenesis transcription cascade. Dev Cell (2009) 1.27
Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem (2003) 1.22
Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. J Neurosci (2005) 1.21
Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1). J Nutr (2004) 1.20
Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal. Proc Natl Acad Sci U S A (2005) 1.17
Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae. Proc Natl Acad Sci U S A (2009) 1.13
Site-specific (18)F-labeling of the protein hormone leptin using a general two-step ligation procedure. J Am Chem Soc (2008) 1.13
Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proc Natl Acad Sci U S A (2008) 1.09
Transgenic mice expressing green fluorescent protein under the control of the corticotropin-releasing hormone promoter. Endocrinology (2009) 1.08
Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity. Proc Natl Acad Sci U S A (2003) 1.06
Stearoyl-CoA desaturase-1 and the metabolic syndrome. Curr Drug Targets Immune Endocr Metabol Disord (2003) 1.04
Induction of leptin receptor expression in the liver by leptin and food deprivation. J Biol Chem (2005) 1.01
Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar. Elife (2013) 1.01
Contrasting effects of leptin on food anticipatory and total locomotor activity. PLoS One (2011) 1.01
Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin. Endocrinology (2005) 1.01
Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. Hum Mol Genet (2010) 0.98
Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J Cell Physiol (2003) 0.98
Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. J Comp Neurol (2005) 0.97
The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer. Cell Cycle (2009) 0.94
Candidate genes involved in cardiovascular risk factors by a family-based association study on the island of Kosrae, Federated States of Micronesia. Am J Med Genet (2002) 0.94
Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism. Exp Cell Res (2008) 0.92
Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. J Cell Physiol (2002) 0.92
Phytosterolemia on the island of Kosrae: founder effect for a novel ABCG8 mutation results in high carrier rate and increased plasma plant sterol levels. J Lipid Res (2004) 0.89
Molecular annotation of integrative feeding neural circuits. Cell Metab (2011) 0.85
Epigenetic alterations and microRNA misexpression in cancer and autoimmune diseases: a critical review. Clin Rev Allergy Immunol (2014) 0.84
Creating a flexible multiple microRNA expression vector by linking precursor microRNAs. Biochem Biophys Res Commun (2011) 0.83
European admixture on the Micronesian island of Kosrae: lessons from complete genetic information. Eur J Hum Genet (2009) 0.83
Cytokine-induced patterns of gene expression in skeletal muscle tissue. J Biol Chem (2003) 0.80
Developmental role for endocannabinoid signaling in regulating glucose metabolism and growth. Diabetes (2013) 0.79
Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor. PLoS One (2013) 0.79
Corrigendum: Remote regulation of glucose homeostasis in mice using genetically encoded nanoparticles. Nat Med (2015) 0.75
Longitudinal study shows increasing obesity and hyperglycemia in micronesia. Obesity (Silver Spring) (2013) 0.75
Brachytherapy catheter spacing and stabilization technique. Brachytherapy (2012) 0.75
A conversation with Jeffrey M. Friedman by Ushma S. Neill. J Clin Invest (2013) 0.75