PubRank

David Warburton

Author PubWeight™ 109.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int J Biochem Cell Biol 2007 3.33
2 Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 2002 2.83
3 TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. EMBO J 2007 2.57
4 Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev Biol 2005 2.23
5 VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis. Dev Biol 2005 1.81
6 Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol 2007 1.74
7 Burkholderia cepacia-induced IL-8 gene expression in an alveolar epithelial cell line: signaling through CD14 and mitogen-activated protein kinase. Pediatr Res 2003 1.74
8 Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc 2011 1.66
9 Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung. Dev Biol 2006 1.64
10 Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol 2010 1.59
11 Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema. Am J Physiol Lung Cell Mol Physiol 2004 1.56
12 miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol 2009 1.56
13 Fibrillin controls TGF-beta activation. Nat Genet 2003 1.53
14 Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. Am J Pathol 2003 1.53
15 Lung development and adult lung diseases. Chest 2007 1.47
16 Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells 2008 1.46
17 Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One 2010 1.44
18 Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells. Am J Physiol Lung Cell Mol Physiol 2003 1.42
19 Developmental biology: order in the lung. Nature 2008 1.36
20 Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. J Pediatr Surg 2005 1.28
21 Development, repair and fibrosis: what is common and why it matters. Respirology 2009 1.24
22 Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair. PLoS One 2011 1.20
23 TACE is required for fetal murine cardiac development and modeling. Dev Biol 2003 1.19
24 A perfusion-independent role of blood vessels in determining branching stereotypy of lung airways. Development 2011 1.18
25 Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 2006 1.15
26 MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells. PLoS One 2012 1.13
27 Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol 2008 1.13
28 Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway. Mech Dev 2007 1.13
29 A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med 2009 1.12
30 Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia. J Pediatr Surg 2004 1.11
31 Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol 2007 1.11
32 Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins. Am J Physiol Lung Cell Mol Physiol 2004 1.11
33 The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem 2012 1.10
34 Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc Am Thorac Soc 2006 1.09
35 The human gamma-glutamyltransferase gene family. Hum Genet 2008 1.08
36 BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction. J Biol Chem 2006 1.07
37 Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development 2011 1.04
38 Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. PLoS One 2012 1.04
39 The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg 2006 1.03
40 FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development 2010 1.03
41 Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation. Methods Mol Biol 2010 1.02
42 Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med 2009 1.01
43 Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha. J Physiol 2009 1.01
44 TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells. Gene 2007 1.00
45 Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development. Dev Biol 2006 1.00
46 Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. Pediatr Res 2009 1.00
47 Branching patterns emerge in a mathematical model of the dynamics of lung development. J Physiol 2013 1.00
48 Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol 2008 0.99
49 Injection of amniotic fluid stem cells delays progression of renal fibrosis. J Am Soc Nephrol 2012 0.98
50 Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J Urol 2010 0.98
51 Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells. J Cell Physiol 2007 0.97
52 Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. BMC Biol 2013 0.95
53 Fibroblast growth factor-10 serves a regulatory role in duodenal development. J Pediatr Surg 2005 0.95
54 A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis. Dev Biol 2005 0.95
55 Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs. Am J Respir Cell Mol Biol 2010 0.92
56 Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease? Proc Am Thorac Soc 2009 0.91
57 Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells. Microbes Infect 2004 0.91
58 The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors. Am J Respir Cell Mol Biol 2011 0.90
59 Cell polarity and spindle orientation in the distal epithelium of embryonic lung. Dev Dyn 2011 0.90
60 Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol 2011 0.89
61 Functional analysis of the human Sprouty2 gene promoter. Gene 2003 0.89
62 Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse. J Pediatr Surg 2002 0.88
63 Bcr and Abr cooperate in negatively regulating acute inflammatory responses. Mol Cell Biol 2009 0.87
64 Smad1 expression and function during mouse embryonic lung branching morphogenesis. Am J Physiol Lung Cell Mol Physiol 2005 0.87
65 Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-alpha. Biochem Biophys Res Commun 2008 0.87
66 Entrained pulmonary clocks: epithelium and vasculature keeping pace. Am J Physiol Lung Cell Mol Physiol 2010 0.86
67 Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol 2012 0.86
68 Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice. Am J Physiol Lung Cell Mol Physiol 2011 0.86
69 Water level management and contaminant exposure to tree swallows nesting on the Upper Mississippi River. Environ Monit Assess 2007 0.86
70 Amniotic fluid stem cells inhibit the progression of bleomycin-induced pulmonary fibrosis via CCL2 modulation in bronchoalveolar lavage. PLoS One 2013 0.86
71 Carbon monoxide pollution and lung function in urban compared with rural Mongolian children. Respirology 2011 0.85
72 Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis. Am J Physiol Lung Cell Mol Physiol 2004 0.85
73 Transforming growth factor-beta3 affects plasminogen activator inhibitor-1 expression in fetal mice and modulates fibroblast-mediated collagen gel contraction. Wound Repair Regen 2006 0.85
74 Fibroblast growth factor 10 (Fgf10) invalidation results in anorectal malformation in mice. J Pediatr Surg 2004 0.85
75 Isolation and characterization of distal lung progenitor cells. Methods Mol Biol 2012 0.85
76 Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty. Cancer Biol Ther 2011 0.85
77 Genes and signals regulating murine trophoblast cell development. Mech Dev 2009 0.84
78 Differential expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in early and late gestational mouse skin and skin wounds. Wound Repair Regen 2002 0.84
79 Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response. Am J Physiol Lung Cell Mol Physiol 2011 0.84
80 Selenium and metal concentrations in waterbird eggs and chicks at Agassiz National Wildlife Refuge, Minnesota. Arch Environ Contam Toxicol 2007 0.84
81 Wound healing in development. Birth Defects Res C Embryo Today 2012 0.83
82 Mouse embryonic lung culture, a system to evaluate the molecular mechanisms of branching. J Vis Exp 2010 0.82
83 Trace element concentrations and bioindicator responses in tree swallows from northwestern Minnesota. Environ Monit Assess 2006 0.81
84 Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J Cell Sci 2012 0.81
85 Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling. Dev Biol 2013 0.81
86 Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2013 0.81
87 Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium. J Histochem Cytochem 2012 0.80
88 Cell-based therapies for lung disease. Br Med Bull 2012 0.80
89 Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin α6β1-ADAM17/tumor necrosis factor-α-converting enzyme (TACE) signaling pathway. J Biol Chem 2013 0.80
90 On the derivation and clinical implications of "driver" mutations in lung cancer. Am J Respir Crit Care Med 2010 0.79
91 Stem cells: a recapitulation of development. Respirology 2013 0.79
92 Alterations in deoxyribonucleic acid (DNA) methylation patterns of Calca, Timp3, Mmp2, and Igf2r are associated with chronic cystitis in a cyclophosphamide-induced mouse model. Urology 2013 0.78
93 Centrifugal migration of mesenchymal cells in embryonic lung. Dev Dyn 2008 0.78
94 FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. Dev Biol 2012 0.78
95 Mesenchymal-specific inhibition of vascular endothelial growth factor (VEGF) attenuates growth in neonatal mice. J Surg Res 2011 0.78
96 Infection-induced kinin B1 receptors in human pulmonary fibroblasts: role of intact pathogens and p38 mitogen-activated protein kinase-dependent signaling. J Pharmacol Exp Ther 2005 0.77
97 VEGF optimizes the formation of tissue-engineered small intestine. Regen Med 2011 0.77
98 A modified technique for partial pneumonectomy in the mouse. J Invest Surg 2011 0.77
99 Nongenomic estrogen action regulates tyrosine phosphatase activity and tuberin stability. Mol Cell Endocrinol 2003 0.77
100 Dredging and contaminant exposure to tree swallows nesting on the upper Mississippi River. Environ Monit Assess 2013 0.76
101 Impact of stem cells in craniofacial regenerative medicine. Front Physiol 2012 0.76
102 Wingless: developmentally important genes that respond adversely to smoking. Thorax 2013 0.75
103 O-GlcNAc mediated glycosylation down-regulation in mice with cyclophosphamide induced cystitis. J Urol 2010 0.75
104 Sound the tocsin! Beware adverse effects of lung inflammation early in gestation. Am J Respir Crit Care Med 2002 0.75
105 Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479. Development 2017 0.75
106 Overview of Lung Development in the Newborn Human. Neonatology 2017 0.75
107 Introduction: Ninth Lund COPD Symposium. Proc Am Thorac Soc 2009 0.75
108 Murine nitrofen-induced pulmonary hypoplasia does not involve induction of TGF-beta signaling. J Pediatr Surg 2002 0.75
109 Retraction: Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J. Cell. Sci. doi: 10.1242/102848. J Cell Sci 2017 0.75
110 Modulating the alveolar milieu to enhance resolution of fibrotic lung injury. Proc Am Thorac Soc 2012 0.75