Published in J Immunol on February 01, 2006
Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages. Immunity (2007) 4.17
Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis. Crit Care (2006) 3.19
Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal (2011) 1.82
LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways. Proc Natl Acad Sci U S A (2006) 1.40
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J Cell Biol (2008) 1.14
Negative regulatory approaches to the attenuation of Toll-like receptor signaling. Exp Mol Med (2013) 0.99
Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Rep (2013) 0.86
Nucleoredoxin negatively regulates Toll-like receptor 4 signaling via recruitment of flightless-I to myeloid differentiation primary response gene (88). J Biol Chem (2010) 0.86
Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response. J Interferon Cytokine Res (2010) 0.83
Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells. Proteomics (2009) 0.83
Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex. J Proteome Res (2009) 0.81
The influence of Flightless I on Toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing. Biomed Res Int (2013) 0.79
LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium. Mucosal Immunol (2015) 0.77
Lysosomal secretion of Flightless I upon injury has the potential to alter inflammation. Commun Integr Biol (2012) 0.77
Cytoskeletal Regulation of Inflammation and Its Impact on Skin Blistering Disease Epidermolysis Bullosa Acquisita. Int J Mol Sci (2016) 0.75
Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression. Oncotarget (2015) 0.75
Landscape of transcription in human cells. Nature (2012) 20.18
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell (2003) 3.75
PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol (2009) 3.15
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A (2003) 2.91
Long noncoding RNAs are rarely translated in two human cell lines. Genome Res (2012) 2.64
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. Neuron (2002) 2.48
Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A (2004) 2.28
Enhanced reversibility and unusual microstructure of a phase-transforming material. Nature (2013) 2.21
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. Nat Struct Mol Biol (2010) 2.07
Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol Cell Proteomics (2003) 1.77
Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell (2004) 1.73
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell (2007) 1.63
Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A (2006) 1.59
The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation. PLoS Pathog (2009) 1.57
Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection. Anal Biochem (2002) 1.57
Amino acid residue specific stable isotope labeling for quantitative proteomics. Rapid Commun Mass Spectrom (2002) 1.54
A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains. Genes Dev (2002) 1.53
S100A8 and S100A9 in human arterial wall. Implications for atherogenesis. J Biol Chem (2005) 1.52
Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? Cancer Chemother Pharmacol (2009) 1.51
Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling. J Cell Biol (2004) 1.51
Pilot study of oral anthocyanins for colorectal cancer chemoprevention. Cancer Prev Res (Phila) (2009) 1.50
Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER). Lancet (2013) 1.50
Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins. EMBO J (2004) 1.49
Evidence of positive selection on a class I ADH locus. Am J Hum Genet (2007) 1.48
Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity. Mol Pharmacol (2005) 1.47
Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem (2013) 1.47
Modifications of superoxide dismutase (SOD1) in human erythrocytes: a possible role in amyotrophic lateral sclerosis. J Biol Chem (2009) 1.46
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity (2012) 1.44
Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1. J Biol Chem (2009) 1.43
The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex. J Mol Biol (2002) 1.43
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proc Natl Acad Sci U S A (2004) 1.42
Water quality in the upper Han River basin, China: the impacts of land use/land cover in riparian buffer zone. J Hazard Mater (2008) 1.42
Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem (2009) 1.38
Whole human genome proteogenomic mapping for ENCODE cell line data: identifying protein-coding regions. BMC Genomics (2013) 1.38
Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP. J Biol Chem (2002) 1.33
Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway. Stem Cells (2013) 1.33
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. Cancer Discov (2013) 1.32
PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Mol Cell Biol (2012) 1.30
Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization. J Immunol (2003) 1.30
Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation. J Biol Chem (2008) 1.29
Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. J Am Chem Soc (2010) 1.28
Recombinant plasma gelsolin infusion attenuates burn-induced pulmonary microvascular dysfunction. J Appl Physiol (1985) (2003) 1.28
Potential challenges to the Stop TB Plan for humans in China; cattle maintain M. bovis and M. tuberculosis. Tuberculosis (Edinb) (2008) 1.26
Exonuclease I hydrolyzes DNA with a distribution of rates. Biophys J (2004) 1.24
PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. Cancer Res (2005) 1.23
Pentamidine reduces hERG expression to prolong the QT interval. Br J Pharmacol (2005) 1.23
Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol (2009) 1.23
CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer. PLoS One (2011) 1.23
Detection of HPV DNA in esophageal cancer specimens from different regions and ethnic groups: a descriptive study. BMC Cancer (2010) 1.22
Intra- and interpopulation genotype reconstruction from tagging SNPs. Genome Res (2006) 1.21
Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells. Cell Microbiol (2007) 1.18
Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression. Mol Cell Biol (2008) 1.17
Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide. J Biol Chem (2007) 1.16
HDA18 affects cell fate in Arabidopsis root epidermis via histone acetylation at four kinase genes. Plant Cell (2013) 1.16
The prognostic significance of apoptosis-related biological markers in Chinese gastric cancer patients. PLoS One (2011) 1.16
Prolactin modulates the naive B cell repertoire. J Clin Invest (2003) 1.14
S100A12 provokes mast cell activation: a potential amplification pathway in asthma and innate immunity. J Allergy Clin Immunol (2006) 1.14
Hybrid optofluidic integration. Lab Chip (2013) 1.14
Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling. Biochemistry (2003) 1.14
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J Cell Biol (2008) 1.14
Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases. Pflugers Arch (2007) 1.14
Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun. Nat Biotechnol (2006) 1.13
Comparative proteomic analysis of all-trans-retinoic acid treatment reveals systematic posttranscriptional control mechanisms in acute promyelocytic leukemia. Blood (2004) 1.13
S-nitrosylated S100A8: novel anti-inflammatory properties. J Immunol (2008) 1.12
A new and facile synthesis of quinazoline-2,4(1H,3H)-diones. Org Lett (2009) 1.10
Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanisms. J Physiol (2007) 1.10
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biol (2011) 1.09
Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migration. Cancer Res (2011) 1.08
Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding. J Biol Chem (2006) 1.08
Hepatitis C seroprevalence and associated risk factors, Anyang, China. Emerg Infect Dis (2009) 1.07
Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins. J Immunol (2009) 1.06
The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest. Mol Cell Proteomics (2006) 1.06
Progress towards single-molecule DNA sequencing: a one color demonstration. J Biotechnol (2003) 1.06
Synthesis of metal-selenide nanocrystals using selenium dioxide as the selenium precursor. Angew Chem Int Ed Engl (2008) 1.06
Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}. J Biol Chem (2009) 1.04
In vivo dual-tagging proteomic approach in studying signaling pathways in immune response. J Proteome Res (2005) 1.04
The Anyang Esophageal Cancer Cohort Study: study design, implementation of fieldwork, and use of computer-aided survey system. PLoS One (2012) 1.03
Global structure changes associated with Ca2+ activation of full-length human plasma gelsolin. J Biol Chem (2007) 1.03
Discovery and investigation of misincorporation of serine at asparagine positions in recombinant proteins expressed in Chinese hamster ovary cells. J Biol Chem (2009) 1.02
A DNA biochip for on-the-spot multiplexed pathogen identification. Nucleic Acids Res (2006) 1.02
Improvement of image quality and radiation dose of CT perfusion of the brain by means of low-tube voltage (70 KV). Eur Radiol (2014) 1.00
TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation. Proc Natl Acad Sci U S A (2013) 1.00
Hypertonic stress increases phosphatidylinositol 4,5-bisphosphate levels by activating PIP5KIbeta. J Biol Chem (2006) 1.00
Crosstalk between Wnt/β-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One (2013) 1.00
A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition. Mol Immunol (2009) 0.99