Akihisa Iguchi

Author PubWeight™ 106.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Plasma adiponectin plays an important role in improving insulin resistance with glimepiride in elderly type 2 diabetic subjects. Diabetes Care 2003 2.71
2 Mechanisms underlying the impairment of ischemia-induced neovascularization in matrix metalloproteinase 2-deficient mice. Circ Res 2007 2.57
3 A simple method of plaque rupture induction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2006 2.38
4 Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension 2006 2.03
5 Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients. Nutrition 2002 1.48
6 Lack of correlation between total lymphocyte count and nutritional status in the elderly. Clin Nutr 2005 1.44
7 Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia. Circulation 2003 1.35
8 Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice. Arterioscler Thromb Vasc Biol 2006 1.35
9 Statin prevents plaque disruption in apoE-knockout mouse model through pleiotropic effect on acute inflammation. Atherosclerosis 2009 1.24
10 The clock drawing test as a valid screening method for mild cognitive impairment. Dement Geriatr Cogn Disord 2004 1.20
11 l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits. Proc Natl Acad Sci U S A 2005 1.19
12 Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT). Diabetes Metab Res Rev 2006 1.17
13 Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes. Proc Natl Acad Sci U S A 2006 1.16
14 Prevention of gastroesophageal reflux using an application of half-solid nutrients in patients with percutaneous endoscopic gastrostomy feeding. J Am Geriatr Soc 2004 1.12
15 Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries. Am J Pathol 2004 1.07
16 Role of matrix metalloproteinases in vascular remodeling. J Atheroscler Thromb 2003 1.07
17 Toward the realization of a better aged society: messages from gerontology and geriatrics. Geriatr Gerontol Int 2012 1.02
18 Day care service use is associated with lower mortality in community-dwelling frail older people. J Am Geriatr Soc 2006 1.02
19 Is serum albumin a good marker for malnutrition in the physically impaired elderly? Clin Nutr 2006 1.02
20 Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide. J Pharmacol Exp Ther 2011 1.02
21 No association between rs7566605 variant and being overweight in Japanese. Obesity (Silver Spring) 2007 1.01
22 Underuse of medications for chronic diseases in the oldest of community-dwelling older frail Japanese. J Am Geriatr Soc 2006 0.99
23 Nitric oxide and endothelial cellular senescence. Pharmacol Ther 2008 0.99
24 17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide synthase and GTP cyclohydrolase I by high glucose: relevance to postmenopausal diabetic cardiovascular disease. J Pharmacol Exp Ther 2006 0.99
25 Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort. Am J Clin Nutr 2008 0.98
26 The effect of high glucose on NO and O2- through endothelial GTPCH1 and NADPH oxidase. Life Sci 2004 0.96
27 Endothelium-dependent hyperpolarization and relaxation in mesenteric arteries of middle-aged rats: influence of oestrogen. Br J Pharmacol 2002 0.95
28 Age-specific change of prevalence of metabolic syndrome: longitudinal observation of large Japanese cohort. Atherosclerosis 2006 0.94
29 Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group. J Gerontol A Biol Sci Med Sci 2002 0.93
30 Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3. Am J Pathol 2006 0.93
31 Green tea catechins inhibit the cultured smooth muscle cell invasion through the basement barrier. Atherosclerosis 2003 0.90
32 Selective iNOS inhibitor, ONO1714 successfully retards the development of high-cholesterol diet induced atherosclerosis by novel mechanism. Atherosclerosis 2005 0.90
33 Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism. Atherosclerosis 2003 0.90
34 Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients. Neurobiol Aging 2007 0.90
35 Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits. Cardiovasc Res 2004 0.90
36 AT1 blockade attenuates atherosclerotic plaque destabilization accompanied by the suppression of cathepsin S activity in apoE-deficient mice. Atherosclerosis 2010 0.89
37 The nutritional status of frail elderly with care needs according to the mini-nutritional assessment. Clin Nutr 2006 0.89
38 Evaluation of Mini-Nutritional Assessment for Japanese frail elderly. Nutrition 2005 0.89
39 Pitavastatin: efficacy and safety in intensive lipid lowering. Expert Opin Pharmacother 2007 0.88
40 Behavioral, psychological and physical symptoms in group homes for older adults with dementia. Int Psychogeriatr 2006 0.88
41 Association between unmet needs for medication support and all-cause hospitalization in community-dwelling disabled elderly people. J Am Geriatr Soc 2008 0.88
42 Falls of the elderly are associated with burden of caregivers in the community. Int J Geriatr Psychiatry 2006 0.88
43 A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits. Atherosclerosis 2004 0.87
44 Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism. Proc Natl Acad Sci U S A 2006 0.87
45 Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells. Biochim Biophys Acta 2004 0.87
46 Mechanisms of the inhibitory effect of epigallocatechin-3-gallate on cultured human vascular smooth muscle cell invasion. Arterioscler Thromb Vasc Biol 2005 0.87
47 Epigallocatechin-3-gallate binding to MMP-2 inhibits gelatinolytic activity without influencing the attachment to extracellular matrix proteins but enhances MMP-2 binding to TIMP-2. Arch Biochem Biophys 2003 0.87
48 Impact of gender on in-hospital mortality of patients with acute myocardial infarction undergoing percutaneous coronary intervention: an evaluation of the TAMIS-II data. Intern Med 2007 0.86
49 Influence of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction in Japan: a report from TAMIS-II. Diabetes Res Clin Pract 2006 0.86
50 Prevention of late complications by half-solid enteral nutrients in percutaneous endoscopic gastrostomy tube feeding. Gerontology 2004 0.86
51 Association between masticatory performance and anthropometric measurements and nutritional status in the elderly. Geriatr Gerontol Int 2010 0.85
52 Cognitive function in Japanese elderly with type 2 diabetes mellitus. J Diabetes Complications 2004 0.85
53 Green tea catechins inhibit neointimal hyperplasia in a rat carotid arterial injury model by TIMP-2 overexpression. Cardiovasc Res 2004 0.85
54 High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis. Biochim Biophys Acta 2006 0.84
55 Morphological impairments in microglia precede age-related neuronal degeneration in senescence-accelerated mice. Neuropathology 2011 0.84
56 A comparison of depressive mood of older adults in a community, nursing homes, and a geriatric hospital: factor analysis of Geriatric Depression Scale. J Geriatr Psychiatry Neurol 2006 0.83
57 Anti-atherosclerotic effect of beta-blocker with nitric oxide-releasing action on the severe atherosclerosis. J Cardiovasc Pharmacol 2002 0.83
58 Effect of smoking habit on age-related changes in serum lipids: a cross-sectional and longitudinal analysis in a large Japanese cohort. Atherosclerosis 2005 0.83
59 The pleasurable recreational activities among community-dwelling older adults. Arch Gerontol Geriatr 2005 0.83
60 17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells. Biochim Biophys Acta 2003 0.83
61 Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals: changes in the risk for atherosclerotic diseases at various ages. Diabetes Care 2009 0.83
62 Angiogenic activity of bFGF and VEGF suppressed by proteolytic cleavage by neutrophil elastase. Biochem Biophys Res Commun 2007 0.82
63 Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers. Geriatr Gerontol Int 2010 0.81
64 Nitric oxide: inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression. Cardiovasc Res 2004 0.81
65 Influence of behavioral and psychological symptoms of dementia (BPSD) and environment of care on caregivers' burden. Arch Gerontol Geriatr 2005 0.81
66 Depletion of cholinergic neurons in the nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies. Acta Neuropathol 2006 0.81
67 [Terminal care for elderly patients with dementia in two long-term care hospitals]. Nihon Ronen Igakkai Zasshi 2004 0.81
68 Changes in serum lipid levels during a 10 year period in a large Japanese population. A cross-sectional and longitudinal study. Atherosclerosis 2002 0.81
69 Concomitant production of nitric oxide and superoxide in human macrophages. Biochem Biophys Res Commun 2003 0.81
70 Association of renal insufficiency with in-hospital mortality among Japanese patients with acute myocardial infarction undergoing percutaneous coronary interventions. Int Heart J 2006 0.81
71 Prognostic value of serum albumin combined with serum C-reactive protein levels in older hospitalized patients: continuing importance of serum albumin. Aging Clin Exp Res 2006 0.81
72 Lack of body weight measurement is associated with mortality and hospitalization in community-dwelling frail elderly. Clin Nutr 2007 0.81
73 A novel model of occlusive thrombus formation in mice. Lab Invest 2004 0.80
74 Anthropometric measurements of mid-upper arm as a mortality predictor for community-dwelling Japanese elderly: the Nagoya Longitudinal Study of Frail Elderly (NLS-FE). Clin Nutr 2007 0.80
75 The relationship between functional disability and depressive mood in Japanese older adult inpatients. J Geriatr Psychiatry Neurol 2004 0.80
76 [Differences in cardiac management and in-hospital mortality between elderly patients with and without dementia after acute myocardial infarction: findings from TAMIS data]. Nihon Ronen Igakkai Zasshi 2007 0.80
77 End-of-life care at group homes for patients with dementia in Japan. Findings from an analysis of policy-related differences. Arch Gerontol Geriatr 2005 0.80
78 Which two questions of Mini-Mental State Examination (MMSE) should we start from? Arch Gerontol Geriatr 2006 0.80
79 Comparison of medical treatments for the dying in a hospice and a geriatric hospital in Japan. J Palliat Med 2006 0.79
80 [Dietitians' understanding of personalized nutritional guidance--proposals to increase home visits by dietitians]. Nihon Ronen Igakkai Zasshi 2003 0.79
81 A hydroxymethylglutaryl coenzyme A reductase inhibitor improves endothelial function within 7 days in patients with chronic hemodialysis. Int J Cardiol 2009 0.79
82 Gender differences in the dietary lard-induced increase in blood pressure in rats. Hypertension 2002 0.79
83 Depression, quality of life (QoL) and will to live of community-dwelling postmenopausal women in three Asian countries: Korea, China and Japan. Arch Gerontol Geriatr 2010 0.79
84 Pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, blocks vascular smooth muscle cell populated-collagen lattice contraction. J Cardiovasc Pharmacol 2004 0.79
85 Underappreciated predictors for postdischarge mortality in acute hospitalized oldest-old patients. Gerontology 2006 0.79
86 Possible usefulness of apocynin, an NADPH oxidase inhibitor, for nitrate tolerance: prevention of NO donor-induced endothelial cell abnormalities. Am J Physiol Heart Circ Physiol 2007 0.79
87 The longitudinal change in anthropometric measurements and the association with physical function decline in Japanese community-dwelling frail elderly. Br J Nutr 2009 0.78
88 Different glial reactions to hippocampal stab wounds in young adult and aged rats. J Gerontol A Biol Sci Med Sci 2003 0.78
89 [Long-term prognosis and satisfaction after percutaneous endoscopic gastrostomy in a general hospital]. Nihon Ronen Igakkai Zasshi 2002 0.78
90 [High prevalence rate of depression among community-dwelling frail elderly Japanese]. Nihon Ronen Igakkai Zasshi 2006 0.78
91 Role of medial amygdala in controlling hemodynamics via GABA(A) receptor in anesthetized rats. Circ J 2002 0.78
92 Predictive model for assessing cognitive impairment by quantitative electroencephalography. Cogn Behav Neurol 2005 0.78
93 Microdialysis measurement of acetylcholine in rat hippocampus during severe insulin-induced hypoglycemia. Neuro Endocrinol Lett 2006 0.78
94 Nitric oxide (NO) is a new clinical biomarker of survival in the elderly patients and its efficacy might be nearly equal to albumin. Nitric Oxide 2006 0.78
95 Urinary incontinence and behavioral symptoms are independent risk factors for recurrent and injurious falls, respectively, among residents in long-term care facilities. Arch Gerontol Geriatr 2009 0.78
96 Factors associated with nonadherence to medication in community-dwelling disabled older adults in Japan. J Am Geriatr Soc 2010 0.77
97 Matrix metalloproteinase-2 regulates the expression of tissue inhibitor of matrix metalloproteinase-2. Clin Exp Pharmacol Physiol 2010 0.77
98 Estriol retards and stabilizes atherosclerosis through an NO-mediated system. Life Sci 2002 0.77
99 Role of D and E domains in the migration of vascular smooth muscle cells into fibrin gels. Life Sci 2002 0.77
100 Stimulation of the hippocampal glutamate receptor systems induces stress-like responses. Neuro Endocrinol Lett 2006 0.77
101 Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women. Life Sci 2009 0.77
102 Factors associated with cognitive impairment in elderly patients with diabetes mellitus. J Am Geriatr Soc 2006 0.77
103 In vivo assessment of adenoviral vector-mediated gene expression of dopamine D(2) receptors in the rat striatum by positron emission tomography. Synapse 2002 0.77
104 [Gender difference characteristics in the sociodemographic background of care recipients]. Nihon Ronen Igakkai Zasshi 2010 0.77
105 Atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, reduces bone resorption in the elderly. J Am Geriatr Soc 2003 0.76
106 Impact of informal care levels on discontinuation of living at home in community-dwelling dependent elderly using various community-based services. Arch Gerontol Geriatr 2010 0.76
107 Effects of educational background on verbal fluency task performance in older adults with Alzheimer's disease and mild cognitive impairment. Int Psychogeriatr 2010 0.76
108 Dopamine D2 receptor plays a role in memory function: implications of dopamine-acetylcholine interaction in the ventral hippocampus. Psychopharmacology (Berl) 2005 0.76
109 Influence of diabetes mellitus on caregiver burden in home care: a report based on the Nagoya Longitudinal Study of the Frail Elderly (NLS-FE). Geriatr Gerontol Int 2008 0.76
110 Effects of home massage rehabilitation therapy for the bed-ridden elderly: a pilot trial with a three-month follow-up. Clin Rehabil 2005 0.76
111 Association of higher carbohydrate intake with depressive mood in elderly diabetic women. Nutr Neurosci 2009 0.76
112 Responses of hypothalamo-pituitary-adrenal axis to a cholinesterase inhibitor. Neuroreport 2009 0.76
113 Nitric oxide metabolites are associated with survival in older patients. J Am Geriatr Soc 2007 0.76
114 The age-associated changes of dopamine-acetylcholine interaction in the striatum. Exp Gerontol 2003 0.76
115 Functional recovery of the striatal cholinergic system in aged rats by adenoviral vector-mediated gene transfer of dopamine D2 receptor. Mech Ageing Dev 2006 0.76
116 Effect of long-term care insurance on communication/recording tasks for in-home nursing care services. Arch Gerontol Geriatr 2003 0.76
117 Association between feeding via percutaneous endoscopic gastrostomy and low level of caregiver burden. J Am Geriatr Soc 2007 0.76
118 Raised homocysteine and low folate and vitamin B-12 concentrations predict cognitive decline in community-dwelling older Japanese adults. Clin Nutr 2008 0.75
119 [Factors associated with malnutrition in community-dwelling disabled elderly--the KANAGAWA-AICHI Disabled Elderly Cohort (KAIDEC) Study]. Nihon Ronen Igakkai Zasshi 2014 0.75
120 Effect of emergency percutaneous coronary intervention on in-hospital mortality of very elderly (80+ years of age) patients with acute myocardial infarction. Int Heart J 2006 0.75
121 beta1 antagonist and beta2 agonist, celiprolol, restores the impaired endothelial dependent and independent responses and decreased TNFalpha in rat with type II diabetes. Life Sci 2006 0.75
122 Differences in in-hospital mortality between men and women with acute myocardial infarction undergoing percutaneous coronary intervention in Japan: Tokai Acute Myocardial Infarction Study (TAMIS). Am Heart J 2006 0.75
123 [Attitudes of Japanese general practitioners towards referrals of patients with dementia]. Nihon Ronen Igakkai Zasshi 2007 0.75
124 [Awareness of dementia in older adults attending dementia-prevention programs in community healthcare centers]. Nihon Ronen Igakkai Zasshi 2005 0.75
125 [Proposal for measuring quality of care and perspective for practical use]. Nihon Ronen Igakkai Zasshi 2002 0.75
126 [Anthropometric measurements as a predictor of mortality of community-dwelling Japanese elderly: the Nagoya Longitudinal Study of Frail Elderly (NLS-FE)]. Nihon Ronen Igakkai Zasshi 2007 0.75
127 Age differences in the delivery of cardiac management to women versus men with acute myocardial infarction: an evaluation of the TAMIS-II data. Int Heart J 2006 0.75
128 Cognitive decline in administration of the nonsteroidal antiinflammatory drug loxoprofen with misoprostol in a 91-year-old Japanese woman. J Am Geriatr Soc 2002 0.75
129 [An overview and prospect of demented outpatient care in a department of geriatric medicine: report based on statistical review of the memory clinic at the geriatric outpatient unit of the Nagoya University Hospital]. Nihon Ronen Igakkai Zasshi 2007 0.75
130 [Effects of carvedilol on the hemodynamics and its tolerance in elderly patients]. Nihon Ronen Igakkai Zasshi 2002 0.75
131 Japanese patients with acute myocardial infarction who present without chest pain. Int Heart J 2006 0.75
132 In vivo insulin action in adrenodemedullated rats after voluntary running. Diabetes Res Clin Pract 2004 0.75
133 The long-term effect of estriol on endothelial function and bone mineral density in octogenarian women. J Am Geriatr Soc 2002 0.75
134 The treadmill exercise-tolerance test is useful for the prediction and prevention of ischemic coronary events in elderly diabetics. J Diabetes Complications 2005 0.75
135 Changes in the perception of dementia in Japan. Int Psychogeriatr 2009 0.75
136 Importance of lipid levels in elderly diabetic individuals: baseline characteristics and 1-year survey of cardiovascular events. Circ J 2008 0.75
137 Age-related differences in the delivery of cardiac management to women versus men with acute myocardial infarction in Japan: Tokai Acute Myocardial Infarction Study: TAMIS. Int Heart J 2005 0.75
138 [An elderly case with sarcoidosis whose symptom of dementia was effectively treated by steroid]. Nihon Ronen Igakkai Zasshi 2002 0.75
139 [Target of glycemic control of elderly diabetes mellitus patients]. Nihon Rinsho 2006 0.75
140 [Present status of geriatric care in the world]. Nihon Naika Gakkai Zasshi 2004 0.75
141 Serum uric acid concentrations in type 2 diabetes: its significant relationship to serum 1,5-anhydroglucitol concentrations. Endocr Regul 2005 0.75
142 [Decision-making factors regarding resuscitate and hospitalize orders by families of elderly persons on admission to a Japanese long-term care hospital]. Nihon Ronen Igakkai Zasshi 2007 0.75
143 [The delayed word recall task using ADAS-Jcog word booklet effectively divides patients with mild cognitive impairment from normal elderly people]. Nihon Ronen Igakkai Zasshi 2007 0.75
144 [Home end-of-life care for advanced dementia vs advanced cancer elderly patients: dying elderly at home project]. Nihon Ronen Igakkai Zasshi 2006 0.75
145 [End-of-life care in the curriculum in Japan: a national survey of senior medical students]. Nihon Ronen Igakkai Zasshi 2007 0.75
146 [National survey on the current status of programs to teach end-of-life care to undergraduates of medical and nursing schools in Japan]. Nihon Ronen Igakkai Zasshi 2005 0.75
147 [In Process Citation]. Nihon Ronen Igakkai Zasshi 2015 0.75
148 Attitudes toward disclosing the diagnosis of dementia in Japan. Int Psychogeriatr 2006 0.75
149 The entorhinal cortex regulates blood glucose level in response to microinjection of neostigmine into the hippocampus. Neuro Endocrinol Lett 2005 0.75
150 [Effect of end-of-life care teaching on the attitude of medical students to death]. Nihon Ronen Igakkai Zasshi 2007 0.75
151 Standardization of plasma brain natriuretic peptide concentrations in older Japanese-relationship to latent renal dysfunction and ischemic heart disease. J Am Geriatr Soc 2002 0.75
152 [Management guideline for elderly diabetic patients]. Nihon Rinsho 2002 0.75
153 Aging accelerates dietary lard-induced increase in blood pressure in rats. Exp Gerontol 2003 0.75
154 [The relationship between mental processing speed and white matter lesions in dementia]. Nihon Ronen Igakkai Zasshi 2007 0.75
155 [What is geriatrics?]. Nihon Ronen Igakkai Zasshi 2003 0.75
156 [Relation between destination on discharge in the elderly patients and comprehensive geriatric assessment at admission in the ward of the Geriatric Department of University Hospital]. Nihon Ronen Igakkai Zasshi 2002 0.75
157 [Comprehensive geriatrics--concept of terminal care]. Nihon Naika Gakkai Zasshi 2004 0.75
158 [Diabetic macroangiopathy and NO]. Nihon Rinsho 2004 0.75