Published in Obesity (Silver Spring) on November 01, 2007
Gene-environment interaction and obesity. Nutr Rev (2008) 1.84
Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes. PLoS One (2008) 1.17
INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men. BMC Med Genet (2008) 0.94
INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study. Obesity (Silver Spring) (2009) 0.89
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts. BMC Med Genet (2009) 0.87
INSIG2 variants, dietary patterns and metabolic risk in Samoa. Eur J Clin Nutr (2012) 0.83
A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans. BMC Med Genet (2009) 0.83
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes. BMC Med Genet (2009) 0.80
Association of INSIG2 polymorphism with overweight and LDL in children. PLoS One (2015) 0.76
Gender-Specific Effect of -102G>A Polymorphism in Insulin Induced Gene 2 on Obesity in Chinese Children. Int J Endocrinol (2015) 0.75
INSIG2 is Associated with Lower Gain in Weight-for-Length Between Birth and Age 6 Months. Clin Med Pediatr (2009) 0.75
The Common Genetic Variant of insig2 Gene rs7566605 Polymorphism Is Associated with Severe Obesity in North India Iran Biomed J (2017) 0.75
Mitochondrial genome variation in eastern Asia and the peopling of Japan. Genome Res (2004) 3.34
Plasma adiponectin plays an important role in improving insulin resistance with glimepiride in elderly type 2 diabetic subjects. Diabetes Care (2003) 2.71
Mechanisms underlying the impairment of ischemia-induced neovascularization in matrix metalloproteinase 2-deficient mice. Circ Res (2007) 2.57
A simple method of plaque rupture induction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2006) 2.38
Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure. Hypertension (2006) 2.03
Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women. J Mol Med (Berl) (2004) 1.50
Prevalence of hyperesthesia detected by current perception threshold test in subjects with glucose metabolic impairments in a community. Intern Med (2002) 1.48
Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients. Nutrition (2002) 1.48
Lack of correlation between total lymphocyte count and nutritional status in the elderly. Clin Nutr (2005) 1.44
Deficiency of gelatinase a suppresses smooth muscle cell invasion and development of experimental intimal hyperplasia. Circulation (2003) 1.35
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice. Arterioscler Thromb Vasc Biol (2006) 1.35
Statin prevents plaque disruption in apoE-knockout mouse model through pleiotropic effect on acute inflammation. Atherosclerosis (2009) 1.24
The clock drawing test as a valid screening method for mild cognitive impairment. Dement Geriatr Cogn Disord (2004) 1.20
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits. Proc Natl Acad Sci U S A (2005) 1.19
Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT). Diabetes Metab Res Rev (2006) 1.17
Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes. Proc Natl Acad Sci U S A (2006) 1.16
Mitochondrial ALDH2 deficiency as an oxidative stress. Ann N Y Acad Sci (2004) 1.12
Prevention of gastroesophageal reflux using an application of half-solid nutrients in patients with percutaneous endoscopic gastrostomy feeding. J Am Geriatr Soc (2004) 1.12
A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS One (2013) 1.10
Refractive errors and factors associated with myopia in an adult Japanese population. Jpn J Ophthalmol (2003) 1.08
The relationship between age and intraocular pressure in a Japanese population: the influence of central corneal thickness. Curr Eye Res (2002) 1.07
Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries. Am J Pathol (2004) 1.07
Role of matrix metalloproteinases in vascular remodeling. J Atheroscler Thromb (2003) 1.07
Is there a relevant effect of noise and smoking on hearing? A population-based aging study. Int J Audiol (2005) 1.05
MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study. Stroke (2003) 1.05
Dietary magnesium intake and the future risk of coronary heart disease (the Honolulu Heart Program). Am J Cardiol (2003) 1.04
Day care service use is associated with lower mortality in community-dwelling frail older people. J Am Geriatr Soc (2006) 1.02
Toward the realization of a better aged society: messages from gerontology and geriatrics. Geriatr Gerontol Int (2012) 1.02
Is serum albumin a good marker for malnutrition in the physically impaired elderly? Clin Nutr (2006) 1.02
Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide. J Pharmacol Exp Ther (2011) 1.02
Underuse of medications for chronic diseases in the oldest of community-dwelling older frail Japanese. J Am Geriatr Soc (2006) 0.99
Nitric oxide and endothelial cellular senescence. Pharmacol Ther (2008) 0.99
17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide synthase and GTP cyclohydrolase I by high glucose: relevance to postmenopausal diabetic cardiovascular disease. J Pharmacol Exp Ther (2006) 0.99
High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture. Geriatr Gerontol Int (2012) 0.98
Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort. Am J Clin Nutr (2008) 0.98
The effect of high glucose on NO and O2- through endothelial GTPCH1 and NADPH oxidase. Life Sci (2004) 0.96
Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men. Int J Mol Med (2007) 0.96
Association of polymorphisms of the osteoprotegerin gene with bone mineral density in Japanese women but not men. Mol Genet Metab (2003) 0.96
Prevalence of knee pain, lumbar pain and its coexistence in Japanese men and women: The Longitudinal Cohorts of Motor System Organ (LOCOMO) study. J Bone Miner Metab (2013) 0.95
Endothelium-dependent hyperpolarization and relaxation in mesenteric arteries of middle-aged rats: influence of oestrogen. Br J Pharmacol (2002) 0.95
The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness. Ophthalmic Physiol Opt (2004) 0.94
Age-specific change of prevalence of metabolic syndrome: longitudinal observation of large Japanese cohort. Atherosclerosis (2006) 0.94
Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group. J Gerontol A Biol Sci Med Sci (2002) 0.93
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss. Laryngoscope (2010) 0.93
Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3. Am J Pathol (2006) 0.93
Impact of caregiver burden on adverse health outcomes in community-dwelling dependent older care recipients. Am J Geriatr Psychiatry (2011) 0.92
Association of polymorphisms of interleukin-6, osteocalcin, and vitamin D receptor genes, alone or in combination, with bone mineral density in community-dwelling Japanese women and men. J Clin Endocrinol Metab (2003) 0.92
The impact of health problems on depression and activities in middle-aged and older adults: age and social interactions as moderators. J Gerontol B Psychol Sci Soc Sci (2004) 0.91
Age differences in the effect of physical activity on depressive symptoms. Psychol Aging (2004) 0.91
Association of the mitochondrial DNA 15497G/A polymorphism with obesity in a middle-aged and elderly Japanese population. Hum Genet (2003) 0.91
Green tea catechins inhibit the cultured smooth muscle cell invasion through the basement barrier. Atherosclerosis (2003) 0.90
Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits. Cardiovasc Res (2004) 0.90
Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients. Neurobiol Aging (2007) 0.90
Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism. Atherosclerosis (2003) 0.90
Polymorphisms in genes involved in inflammatory pathways in patients with sudden sensorineural hearing loss. J Neurogenet (2012) 0.90
Selective iNOS inhibitor, ONO1714 successfully retards the development of high-cholesterol diet induced atherosclerosis by novel mechanism. Atherosclerosis (2005) 0.90
Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study. BMC Med Genet (2011) 0.89
Genetic deficiency of a mitochondrial aldehyde dehydrogenase increases serum lipid peroxides in community-dwelling females. J Hum Genet (2003) 0.89
Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density of the femoral neck in elderly Japanese women. J Mol Med (Berl) (2002) 0.89
AT1 blockade attenuates atherosclerotic plaque destabilization accompanied by the suppression of cathepsin S activity in apoE-deficient mice. Atherosclerosis (2010) 0.89
The nutritional status of frail elderly with care needs according to the mini-nutritional assessment. Clin Nutr (2006) 0.89
The effects of aging on distortion-product otoacoustic emissions in adults with normal hearing. Ear Hear (2008) 0.89
Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from a middle-aged Japanese population. Br J Nutr (2009) 0.89
Evaluation of Mini-Nutritional Assessment for Japanese frail elderly. Nutrition (2005) 0.89
Pitavastatin: efficacy and safety in intensive lipid lowering. Expert Opin Pharmacother (2007) 0.88
Behavioral, psychological and physical symptoms in group homes for older adults with dementia. Int Psychogeriatr (2006) 0.88
Dietary supplement use by community-living population in Japan: data from the National Institute for Longevity Sciences Longitudinal Study of Aging (NILS-LSA). J Epidemiol (2006) 0.88