Published in Cancer Res on February 01, 2006
Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Semin Cancer Biol (2010) 1.91
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development. Proc Natl Acad Sci U S A (2010) 1.55
Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. PLoS One (2007) 1.50
Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy. Cancer Res (2009) 1.44
Identification of a novel inhibitor of the canonical Wnt pathway. Mol Cell Biol (2011) 1.38
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer. EMBO Mol Med (2013) 1.38
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun (2015) 1.35
Wnt signaling in ovarian tumorigenesis. Int J Gynecol Cancer (2007) 1.35
Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding. Nat Med (2013) 1.33
Oncogenic potential of the nuclear receptor coregulator proline-, glutamic acid-, leucine-rich protein 1/modulator of the nongenomic actions of the estrogen receptor. Cancer Res (2007) 1.28
VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway. PLoS One (2009) 1.28
Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Oncogene (2010) 1.26
HtrA serine proteases as potential therapeutic targets in cancer. Curr Cancer Drug Targets (2009) 1.25
Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development. Development (2011) 1.19
DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. BMC Med Genomics (2008) 1.17
Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer. Oncotarget (2014) 1.14
Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer. Oncotarget (2012) 1.12
miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 and NTM, respectively at an early stage following sciatic nerve injury. Nucleic Acids Res (2012) 1.12
Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem (2010) 1.10
miR-26a suppresses tumor growth and metastasis by targeting FGF9 in gastric cancer. PLoS One (2013) 1.09
An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription. Nucleic Acids Res (2011) 1.08
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
Molecular pathology of the fibroblast growth factor family. Hum Mutat (2009) 1.06
Differential expression of CHL1 gene during development of major human cancers. PLoS One (2011) 1.06
Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J (2011) 1.05
Pharmacological modulation of beta-catenin and its applications in cancer therapy. J Cell Mol Med (2013) 1.03
miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14. Cancer Res (2015) 1.03
Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation. Biochim Biophys Acta (2008) 1.03
Smad3 protein levels are modulated by Ras activity and during the cell cycle to dictate transforming growth factor-beta responses. J Biol Chem (2009) 1.02
Wnt and hedgehog gene pathway expression in serous ovarian cancer. Int J Gynecol Cancer (2011) 1.02
Overexpression and mislocalization of the chromosomal segregation protein separase in multiple human cancers. Clin Cancer Res (2009) 1.01
Prostaglandin E2 induces fibroblast growth factor 9 via EP3-dependent protein kinase Cdelta and Elk-1 signaling. Mol Cell Biol (2006) 1.01
Role of Pirh2 in mediating the regulation of p53 and c-Myc. PLoS Genet (2011) 0.99
Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta. Carcinogenesis (2008) 0.99
Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker. PLoS One (2013) 0.98
Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes. Transl Oncol (2009) 0.97
Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis. PLoS One (2009) 0.95
Elevated and secreted phospholipase A₂ activities as new potential therapeutic targets in human epithelial ovarian cancer. FASEB J (2012) 0.94
Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice. J Biol Chem (2012) 0.93
Robust multi-tissue gene panel for cancer detection. BMC Cancer (2010) 0.91
Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3. Cancer Res (2013) 0.91
Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra. PLoS One (2011) 0.90
MSX2 is an oncogenic downstream target of activated WNT signaling in ovarian endometrioid adenocarcinoma. Oncogene (2011) 0.90
FUBP3 interacts with FGF9 3' microsatellite and positively regulates FGF9 translation. Nucleic Acids Res (2011) 0.89
Rsf-1, a chromatin remodelling protein, interacts with cyclin E1 and promotes tumour development. J Pathol (2013) 0.89
FGF16 promotes invasive behavior of SKOV-3 ovarian cancer cells through activation of mitogen-activated protein kinase (MAPK) signaling pathway. J Biol Chem (2013) 0.88
The atypical histone macroH2A1.2 interacts with HER-2 protein in cancer cells. J Biol Chem (2012) 0.88
WNT7A/β-catenin signaling induces FGF1 and influences sensitivity to niclosamide in ovarian cancer. Oncogene (2014) 0.87
Integrative bioinformatics links HNF1B with clear cell carcinoma and tumor-associated thrombosis. PLoS One (2013) 0.86
AUF1 p42 isoform selectively controls both steady-state and PGE2-induced FGF9 mRNA decay. Nucleic Acids Res (2010) 0.85
MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome. BMC Cancer (2010) 0.85
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer. Nucleic Acids Res (2015) 0.84
Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer. Cell Cycle (2013) 0.84
Gene expression profile in colon cancer cells with respect to XIAP expression status. Int J Colorectal Dis (2008) 0.84
Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci (2010) 0.84
Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res (2015) 0.84
A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. J Lipid Res (2011) 0.84
Interleukin-6 receptor enhances early colonization of the murine omentum by upregulation of a mannose family receptor, LY75, in ovarian tumor cells. Clin Exp Metastasis (2011) 0.83
Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma. Mol Cancer Ther (2013) 0.83
Mutant BRAF induces DNA strand breaks, activates DNA damage response pathway, and up-regulates glucose transporter-1 in nontransformed epithelial cells. Am J Pathol (2012) 0.83
Suppression of GNAI2 message in ovarian cancer. J Ovarian Res (2014) 0.81
Gene expression of the lysophosphatidic acid receptor 1 is a target of transforming growth factor beta. Oncogene (2012) 0.81
In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer. BMC Syst Biol (2011) 0.80
Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling. Oncogene (2016) 0.80
Estimating developmental states of tumors and normal tissues using a linear time-ordered model. BMC Bioinformatics (2011) 0.80
FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. BMC Cancer (2015) 0.80
Expression and prognostic significance of wnt7a in human endometrial carcinoma. Obstet Gynecol Int (2012) 0.79
Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer. Genome Med (2016) 0.78
Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3. Cell Mol Neurobiol (2009) 0.78
Expression of YY1 correlates with progression and metastasis in esophageal squamous cell carcinomas. Onco Targets Ther (2014) 0.77
Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells. Cancer Lett (2017) 0.76
Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody. Dis Model Mech (2016) 0.76
Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome. Oncotarget (2016) 0.76
Overcoming inherent resistance to histone deacetylase inhibitors in multiple myeloma cells by targeting pathways integral to the actin cytoskeleton. Cell Death Dis (2014) 0.76
A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1. BMC Cancer (2015) 0.76
Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic Acids Res (2013) 0.76
A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study. BMC Genomics (2012) 0.76
Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells. J Biol Chem (2012) 0.76
Activin A Stimulates Migration of the Fallopian Tube Epithelium, an Origin of High-Grade Serous Ovarian Cancer, through Non-Canonical Signaling. Cancer Lett (2017) 0.75
Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep (2016) 0.75
Studies on the interaction of tumor-derived HD5 alpha defensins with adenoviruses and implications for oncolytic adenovirus therapy. J Virol (2017) 0.75
The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer. Oncotarget (2016) 0.75
Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS One (2015) 0.75
Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization. Clin Exp Metastasis (2012) 0.75
Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med (2008) 10.12
Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell (2009) 7.09
p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol (2007) 6.87
The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res (2002) 6.47
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol (2006) 4.55
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature (2012) 4.41
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res (2003) 4.30
A biomarker panel for acute graft-versus-host disease. Blood (2008) 3.83
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One (2009) 3.66
Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res (2002) 3.62
Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. J Biol Chem (2002) 3.34
Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem (2005) 3.03
Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell (2007) 3.02
Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Res (2007) 2.97
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Nat Genet (2006) 2.92
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev (2003) 2.59
Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol (2002) 2.44
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol (2003) 2.38
Cadherin and catenin alterations in human cancer. Genes Chromosomes Cancer (2002) 2.32
Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest (2011) 2.32
Survivin and molecular pathogenesis of colorectal cancer. Lancet (2003) 2.25
FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development. EMBO J (2004) 2.24
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J Cell Biol (2011) 2.19
ConceptGen: a gene set enrichment and gene set relation mapping tool. Bioinformatics (2009) 2.11
Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. Cancer Cell (2009) 2.04
Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals. Chromosoma (2002) 2.03
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. Clin Cancer Res (2003) 2.01
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol (2009) 1.99
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis. Oncogene (2005) 1.99
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals. J Cell Sci (2004) 1.98
Direct identification of Staphylococcus aureus from positive blood culture bottles. J Clin Microbiol (2003) 1.97
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data. BMC Bioinformatics (2005) 1.96
Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis. Am J Pathol (2003) 1.92
Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat Neurosci (2004) 1.89
Protein profiles associated with survival in lung adenocarcinoma. Proc Natl Acad Sci U S A (2003) 1.86
Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool. Gastroenterology (2011) 1.86
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation. Cancer Cell (2002) 1.86
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells. Cancer Cell (2003) 1.81
Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2. Immunity (2013) 1.77
Molecular classification and prognostication of adrenocortical tumors by transcriptome profiling. Clin Cancer Res (2009) 1.76
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol (2012) 1.75
CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors. Am J Pathol (2004) 1.72
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells. Blood (2011) 1.67
CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology (2002) 1.62
The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. Cancer Res (2002) 1.60
Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. J Hypertens (2002) 1.55
Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res (2007) 1.53
NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells. J Hypertens (2003) 1.52
Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas. Cancer Res (2003) 1.46
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity (2008) 1.43
Comparison of the cardiovascular protection by omapatrilat and lisinopril treatments in DOCA-salt hypertension. J Hypertens (2003) 1.40
Role of the dependence receptor DCC in colorectal cancer pathogenesis. J Clin Oncol (2004) 1.40
In-depth characterization of microRNA transcriptome in melanoma. PLoS One (2013) 1.38
Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma. J Clin Endocrinol Metab (2008) 1.37
In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe. PLoS One (2011) 1.36
TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling. Cancer Res (2003) 1.31
The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma. Pancreas (2004) 1.31
Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays. Blood (2003) 1.30
Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and corresponding mRNA expression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-beta-Induced epithelial-mesenchymal transition. J Proteome Res (2009) 1.29
Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli. Microb Cell Fact (2011) 1.29
Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis. BMC Cancer (2005) 1.28
COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion. J Clin Invest (2010) 1.28
Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator. Physiol Genomics (2003) 1.28
Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Mol Cancer Res (2005) 1.27
Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. Clin Cancer Res (2006) 1.27
Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer. Cancer Res (2006) 1.26
Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma. Cancer (2004) 1.26
Cervical cancer. J Natl Compr Canc Netw (2013) 1.24
Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin. Am J Pathol (2012) 1.23
Oxidative stress in hypertension. Clin Exp Hypertens (2005) 1.23
Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion. Cancer Res (2005) 1.23