Published in J Immunol on February 15, 2006
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol (2010) 2.36
Neutrophils in the pathogenesis and manifestations of SLE. Nat Rev Rheumatol (2011) 1.73
Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond. Autoimmunity (2008) 1.23
Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. J Immunol (2009) 1.13
Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity. Semin Immunopathol (2013) 1.09
Intracellular nucleic acid sensors and autoimmunity. J Interferon Cytokine Res (2011) 1.07
The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus. J Immunol (2009) 1.06
IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids. J Immunol (2013) 1.06
Apoptotic cell death and lupus. Springer Semin Immunopathol (2006) 1.02
Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus. J Immunol (2013) 1.00
Sensors of the innate immune system: their link to rheumatic diseases. Nat Rev Rheumatol (2010) 1.00
Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes. Gene (2011) 0.96
Neutrophil Extracellular Traps and Systemic Lupus Erythematosus. J Clin Cell Immunol (2013) 0.95
At the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases. J Leukoc Biol (2015) 0.94
Dysfunctional, pro-inflammatory HDL directly upregulates monocyte PDGFRβ, chemotaxis and TNFα production. Clin Immunol (2010) 0.89
The role of aldosterone blockade in murine lupus nephritis. Arthritis Res Ther (2008) 0.88
Macrophage depletion ameliorates nephritis induced by pathogenic antibodies. J Autoimmun (2014) 0.88
Mesangial cells of lupus-prone mice are sensitive to chemokine production. Arthritis Res Ther (2007) 0.86
Aberrant T cell ERK pathway signaling and chromatin structure in lupus. Autoimmun Rev (2008) 0.85
Exposure to nuclear antigens contributes to the induction of humoral autoimmunity during tumour necrosis factor alpha blockade. Ann Rheum Dis (2008) 0.85
Potential functional role of plasmacytoid dendritic cells in cancer immunity. Immunology (2007) 0.84
DNase1 activity in systemic lupus erythematosus patients with and without nephropathy. Rheumatol Int (2009) 0.83
Cytokine-induced monocyte characteristics in SLE. J Biomed Biotechnol (2010) 0.82
The effect of cell death in the initiation of lupus nephritis. Clin Exp Immunol (2015) 0.81
Major pathogenic steps in human lupus can be effectively suppressed by nucleosomal histone peptide epitope-induced regulatory immunity. Clin Immunol (2013) 0.81
Sialoadhesin deficiency does not influence the severity of lupus nephritis in New Zealand black x New Zealand white F1 mice. Arthritis Res Ther (2013) 0.80
Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice. J Immunol (2008) 0.80
PD-L1-expressing neutrophils as a novel indicator to assess disease activity and severity of systemic lupus erythematosus. Arthritis Res Ther (2016) 0.80
Macrophage polarization in kidney diseases. Macrophage (Houst) (2015) 0.78
The Autoimmune Ecology. Front Immunol (2016) 0.77
Influence of vitamin D on cell cycle, apoptosis, and some apoptosis related molecules in systemic lupus erythematosus. Iran J Basic Med Sci (2015) 0.77
Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus. Cell Death Dis (2016) 0.77
Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage. Cell Death Differ (2016) 0.76
An Lck-cre transgene accelerates autoantibody production and lupus development in (NZB × NZW)F1 mice. Lupus (2015) 0.76
Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis. Clin Immunol (2016) 0.76
Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis. PLoS One (2016) 0.75
Toll-like receptor-mediated immune responses in intestinal macrophages; implications for mucosal immunity and autoimmune diseases. Clin Immunol (2016) 0.75
Alterations in nuclear structure promote lupus autoimmunity in a mouse model. Dis Model Mech (2016) 0.75
Estrogen receptor alpha promotes lupus in (NZB×NZW)F1 mice in a B cell intrinsic manner. Clin Immunol (2016) 0.75
The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis. Clin Immunol (2016) 0.75
Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney. Sci Rep (2017) 0.75
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci U S A (2002) 3.85
Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol (2011) 3.83
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J Exp Med (2002) 3.83
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med (2013) 3.70
Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities. Adv Drug Deliv Rev (2003) 3.25
The MAPK signalling pathways and colorectal cancer. Lancet Oncol (2005) 3.10
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med (2006) 2.57
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol (2011) 2.53
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol (2010) 2.36
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest (2011) 2.21
A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc Natl Acad Sci U S A (2004) 2.10
Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis. Circ Res (2014) 1.93
Population-based incidence and prevalence of systemic lupus erythematosus: the Michigan Lupus Epidemiology and Surveillance program. Arthritis Rheumatol (2014) 1.91
Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. J Immunol (2011) 1.85
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. J Immunol (2005) 1.83
Interferon-alpha promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis. Blood (2007) 1.79
An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage. Arthritis Rheumatol (2014) 1.78
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. J Clin Invest (2013) 1.64
Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum (2002) 1.62
Interferon-α and angiogenic dysregulation in pregnant lupus patients who develop preeclampsia. Arthritis Rheumatol (2015) 1.61
Expulsion of small molecules in vesicles shed by cancer cells: association with gene expression and chemosensitivity profiles. Cancer Res (2003) 1.59
Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis. Arthritis Res Ther (2012) 1.57
Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity. Blood (2004) 1.57
The epigenetic face of systemic lupus erythematosus. J Immunol (2006) 1.55
Women in academic rheumatology. Arthritis Rheum (2005) 1.49
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus. Arthritis Rheum (2013) 1.49
Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages. J Immunol (2012) 1.44
Vitamin D deficiency, interleukin 17, and vascular function in rheumatoid arthritis. J Rheumatol (2013) 1.44
The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol (2010) 1.42
Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus. Ann Rheum Dis (2011) 1.41
Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice. EMBO Mol Med (2011) 1.38
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharm Res (2002) 1.37
Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus. J Immunol (2006) 1.33
The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells. J Immunol (2002) 1.29
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients. Ann Rheum Dis (2010) 1.26
Lupus neutrophils: 'NET' gain in understanding lupus pathogenesis. Curr Opin Rheumatol (2012) 1.25
Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond. Autoimmunity (2008) 1.23
Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice. Am J Pathol (2010) 1.23
Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum (2011) 1.19
Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase. J Biol Chem (2003) 1.19
Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis. Arthritis Rheum (2012) 1.18
Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease. Environ Health Perspect (2008) 1.17
Listeriolysin O-liposome-mediated cytosolic delivery of macromolecule antigen in vivo: enhancement of antigen-specific cytotoxic T lymphocyte frequency, activity, and tumor protection. Biochim Biophys Acta (2002) 1.16
Estrogen regulates CCR gene expression and function in T lymphocytes. J Immunol (2005) 1.15
Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol (2013) 1.15
Increased asymmetric dimethylarginine and endothelin 1 levels in secondary Raynaud's phenomenon: implications for vascular dysfunction and progression of disease. Arthritis Rheum (2003) 1.13
Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. J Immunol (2009) 1.13
Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus. Annu Rev Med (2012) 1.13
Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases. Front Immunol (2012) 1.11
Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients. PLoS One (2012) 1.11
Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity. Semin Immunopathol (2013) 1.09
The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis? Curr Opin Rheumatol (2014) 1.08
Epigenetic mechanisms in lupus. Curr Opin Rheumatol (2010) 1.07
Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells. Arthritis Rheum (2012) 1.07
Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression. FASEB J (2012) 1.07
The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus. J Immunol (2009) 1.06
Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis (2011) 1.06
Role of neutrophils in systemic autoimmune diseases. Arthritis Res Ther (2013) 1.05
Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. J Clin Invest (2002) 1.05
Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J Biol Chem (2008) 1.04
Consensus-based reporting standards for diagnostic test accuracy studies for paratuberculosis in ruminants. Prev Vet Med (2011) 1.02
Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus. J Immunol (2013) 1.01
Nuclear autoantigen translocation and autoantibody opsonization lead to increased dendritic cell phagocytosis and presentation of nuclear antigens: a novel pathogenic pathway for autoimmunity? J Immunol (2005) 1.01
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis. Ann Rheum Dis (2013) 1.00
Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum (2012) 0.99
Decreased ERK and JNK signaling contribute to gene overexpression in "senescent" CD4+CD28- T cells through epigenetic mechanisms. J Leukoc Biol (2009) 0.98
Induction of apoptosis by the hydrocarbon oil pristane: implications for pristane-induced lupus. J Immunol (2005) 0.98
The role of neutrophils in the pathogenesis of systemic lupus erythematosus. Curr Opin Rheumatol (2015) 0.98
Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus. J Autoimmun (2011) 0.97
Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate. J Control Release (2008) 0.97
Enhancing the intestinal membrane permeability of zanamivir: a carrier mediated prodrug approach. Mol Pharm (2011) 0.96
Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis. Life Sci (2013) 0.95
Interleukin 17 as a novel predictor of vascular function in rheumatoid arthritis. Ann Rheum Dis (2011) 0.95
Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus. Arthritis Res Ther (2006) 0.95
Localization of protein kinase C epsilon to macrophage vacuoles perforated by Listeria monocytogenes cytolysin. Cell Microbiol (2007) 0.94
Differential cytosolic delivery and presentation of antigen by listeriolysin O-liposomes to macrophages and dendritic cells. Mol Pharm (2005) 0.94
Cardiovascular disease in lupus: insights and updates. Curr Opin Rheumatol (2013) 0.93
Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin. J Immunol (2010) 0.93
Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue. Mol Pharm (2013) 0.92
Poly(ADP-ribose) polymerase-1 regulates the progression of autoimmune nephritis in males by inducing necrotic cell death and modulating inflammation. J Immunol (2009) 0.92
How does interferon-α insult the vasculature? Let me count the ways. Arthritis Rheum (2011) 0.91
Genetic models for the clearance of apoptotic cells. Rheum Dis Clin North Am (2004) 0.91
Myeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onset. J Immunol (2012) 0.91
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors. J Med Chem (2015) 0.90
The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus. Arthritis Res Ther (2011) 0.90
Hemodynamic, autonomic, and vascular effects of exposure to coarse particulate matter air pollution from a rural location. Environ Health Perspect (2014) 0.90
Dendritic cells and the immunopathogenesis of systemic lupus erythematosus. Immunol Res (2007) 0.90
Oxidative stress, T cell DNA methylation, and lupus. Arthritis Rheumatol (2014) 0.90
Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis Rheum (2003) 0.89
Tumor cell killing enabled by listeriolysin O-liposome-mediated delivery of the protein toxin gelonin. J Biol Chem (2003) 0.89
The role of aldosterone blockade in murine lupus nephritis. Arthritis Res Ther (2008) 0.88
Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers. Mol Pharm (2009) 0.88
Prevalence of subclinical atherosclerosis is increased in systemic sclerosis and is associated with serum proteins: a cross-sectional, controlled study of carotid ultrasound. Rheumatology (Oxford) (2013) 0.87
Photoacoustic and ultrasound dual-modality imaging of human peripheral joints. J Biomed Opt (2013) 0.87
Achilles tendinopathy after treatment with ophthalmic moxifloxacin. J Rheumatol (2013) 0.87