Published in J Immunol on December 24, 2012
An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage. Arthritis Rheumatol (2014) 1.78
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat Med (2016) 1.45
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Cell Metab (2017) 1.37
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis (2014) 1.34
Type I interferon in the pathogenesis of lupus. J Immunol (2014) 1.29
Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2. Ann Rheum Dis (2014) 1.25
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Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol (2013) 1.15
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The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis? Curr Opin Rheumatol (2014) 1.08
Role of neutrophils in systemic autoimmune diseases. Arthritis Res Ther (2013) 1.05
Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus. Front Immunol (2013) 1.04
Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus. Arthritis Rheumatol (2014) 1.04
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Antimicrobial cathelicidin peptide LL-37 inhibits the LPS/ATP-induced pyroptosis of macrophages by dual mechanism. PLoS One (2014) 0.90
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Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation. Respir Res (2015) 0.84
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LL-37 modulates human neutrophil responses to influenza A virus. J Leukoc Biol (2014) 0.79
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Detection of SLE antigens in neutrophil extracellular traps (NETs). Methods Mol Biol (2014) 0.78
Human cathelicidin production by the cervix. PLoS One (2014) 0.78
Targeting the inflammasome in rheumatic diseases. Transl Res (2015) 0.77
Roles of cathelicidins in inflammation and bone loss. Odontology (2014) 0.77
Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis. Clin Immunol (2016) 0.76
Review: Neutrophils as Invigorated Targets in Rheumatic Diseases. Arthritis Rheumatol (2016) 0.76
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LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages. Immunology (2016) 0.76
Metabolic Factors that Contribute to Lupus Pathogenesis. Crit Rev Immunol (2016) 0.75
Factor H Binds to Extracellular DNA Traps Released from Human Blood Monocytes in Response to Candida albicans. Front Immunol (2017) 0.75
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Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury. Sci Rep (2016) 0.75
Serum IL-18 as biomarker in predicting long-term renal outcome among pediatric-onset systemic lupus erythematosus patients. Medicine (Baltimore) (2016) 0.75
Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice. Proc Natl Acad Sci U S A (2017) 0.75
The initial inflammatory response to bioactive implants is characterized by NETosis. PLoS One (2015) 0.75
NETosis as Source of Autoantigens in Rheumatoid Arthritis. Front Immunol (2016) 0.75
The danger of sex and death in Scarf1(-/-) autoimmune mice. Nat Immunol (2013) 0.75
Protection against lupus-like inflammatory disease is in the LAP of non-canonical autophagy. Ann Transl Med (2016) 0.75
Biological Activities of Uric Acid in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli. Infect Immun (2016) 0.75
Enhanced inflammasome activity in systemic lupus erythematosus is mediated via type I interferon upregulation of interferon regulatory factor 1. Arthritis Rheumatol (2017) 0.75
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
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Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med (2011) 5.60
Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog (2009) 5.40
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc Natl Acad Sci U S A (2010) 5.05
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Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med (2011) 4.51
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Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis. J Immunol (2005) 2.49
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J Immunol (2004) 2.40
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol (2010) 2.36
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation. Biochem J (2003) 2.25
Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease. J Immunol (2012) 2.12
Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation. J Immunol (2003) 2.02
Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. J Immunol (2011) 1.85
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
Uromodulin triggers IL-1β-dependent innate immunity via the NLRP3 inflammasome. J Am Soc Nephrol (2012) 1.72
Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus. J Leukoc Biol (2012) 1.69
Regulation of extracellular chromatin release from neutrophils. J Innate Immun (2009) 1.64
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis (2012) 1.60
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells. J Immunol (2012) 1.57
Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout. PLoS One (2011) 1.55
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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis Res Ther (2012) 1.49
TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. PLoS One (2012) 1.48
The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol (2010) 1.42
Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways. J Immunol (2007) 1.37
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol (2010) 1.34
Antimicrobial peptides and self-DNA in autoimmune skin inflammation. Curr Opin Immunol (2008) 1.30
P2X7 receptor regulation of non-classical secretion from immune effector cells. Cell Microbiol (2012) 1.28
Lupus neutrophils: 'NET' gain in understanding lupus pathogenesis. Curr Opin Rheumatol (2012) 1.25
LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature. J Immunol (2010) 1.20
Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils. J Cell Biochem (2013) 1.18
Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis. Clin Exp Immunol (2004) 1.11
LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs. PLoS One (2011) 1.08
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci U S A (2003) 1.06
Differing caspase-1 activation states in monocyte versus macrophage models of IL-1beta processing and release. J Leukoc Biol (2004) 1.04
Blockade of IL-18 receptor signaling delays the onset of autoimmune disease in MRL-Faslpr mice. J Immunol (2004) 1.01
Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus. Arthritis Rheum (2008) 0.90
The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages. PLoS One (2012) 0.87
Expressions of IL-18 and its binding protein in peripheral blood leukocytes and kidney tissues of lupus nephritis patients. Clin Rheumatol (2010) 0.87
Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa. Br J Dermatol (2012) 0.86
Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol (2011) 3.83
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med (2013) 3.70
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol (2011) 2.53
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol (2010) 2.36
Retracted A BLOC-1 mutation screen reveals that PLDN is mutated in Hermansky-Pudlak Syndrome type 9. Am J Hum Genet (2011) 2.25
Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis. Circ Res (2014) 1.93
Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus. J Immunol (2011) 1.85
Interferon-alpha promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis. Blood (2007) 1.79
An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage. Arthritis Rheumatol (2014) 1.78
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. J Clin Invest (2013) 1.64
Interferon-α and angiogenic dysregulation in pregnant lupus patients who develop preeclampsia. Arthritis Rheumatol (2015) 1.61
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Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity. Blood (2004) 1.57
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The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol (2010) 1.42
Aberrant phenotype and function of myeloid dendritic cells in systemic lupus erythematosus. J Immunol (2006) 1.33
Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus. J Immunol (2006) 1.28
Lupus neutrophils: 'NET' gain in understanding lupus pathogenesis. Curr Opin Rheumatol (2012) 1.25
Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis. Arthritis Rheum (2012) 1.18
Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol (2013) 1.15
Increased asymmetric dimethylarginine and endothelin 1 levels in secondary Raynaud's phenomenon: implications for vascular dysfunction and progression of disease. Arthritis Rheum (2003) 1.13
Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. J Immunol (2009) 1.13
Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupus. Annu Rev Med (2012) 1.13
Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases. Front Immunol (2012) 1.11
Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients. PLoS One (2012) 1.11
Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity. Semin Immunopathol (2013) 1.09
The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis? Curr Opin Rheumatol (2014) 1.08
The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus. J Immunol (2009) 1.06
Role of neutrophils in systemic autoimmune diseases. Arthritis Res Ther (2013) 1.05
Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus. J Immunol (2013) 1.01
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis. Ann Rheum Dis (2013) 1.00
The role of neutrophils in the pathogenesis of systemic lupus erythematosus. Curr Opin Rheumatol (2015) 0.98
Dysregulation of galectin-3. Implications for Hermansky-Pudlak syndrome pulmonary fibrosis. Am J Respir Cell Mol Biol (2014) 0.96
Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis. Life Sci (2013) 0.95
Interleukin 17 as a novel predictor of vascular function in rheumatoid arthritis. Ann Rheum Dis (2011) 0.95
Cardiovascular disease in lupus: insights and updates. Curr Opin Rheumatol (2013) 0.93
How does interferon-α insult the vasculature? Let me count the ways. Arthritis Rheum (2011) 0.91
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors. J Med Chem (2015) 0.90
The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus. Arthritis Res Ther (2011) 0.90
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The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus. Clin Immunol (2013) 0.83
A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8. Pigment Cell Melanoma Res (2012) 0.82
Jumbled NETs promote vasculitis. Arthritis Rheum (2012) 0.80
Determinants of vascular function in patients with chronic gout. J Clin Hypertens (Greenwich) (2010) 0.80
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Plasminogen activator inhibitor-1 is associated with impaired endothelial function in women with systemic lupus erythematosus. Ann N Y Acad Sci (2005) 0.77
Extracellular chromatin traps interconnect cell biology, microbiology, and immunology. Front Immunol (2013) 0.76
Disentangling the role of neutrophil extracellular traps in rheumatic diseases. Curr Opin Rheumatol (2017) 0.75
Update on cardiovascular disease in lupus. Curr Opin Rheumatol (2016) 0.75
CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest (2017) 0.75
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Retraction Notice to: A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9. Am J Hum Genet (2017) 0.75
Metabolic abnormalities and oxidative stress in lupus. Curr Opin Rheumatol (2017) 0.75