Published in J Biol Chem on February 13, 2006
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Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coli. Infect Immun (2010) 1.10
Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals. Toxins (Basel) (2012) 1.10
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Immunohistologic techniques for detecting the glycolipid Gb(3) in the mouse kidney and nervous system. Histochem Cell Biol (2008) 0.92
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Advances in our understanding of the pathogenesis of glomerular thrombotic microangiopathy. Pediatr Nephrol (2010) 0.89
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GMab-1, a high-affinity anti-3'-isoLM1/3',6'-isoLD1 IgG monoclonal antibody, raised in lacto-series ganglioside-defective knockout mice. Biochem Biophys Res Commun (2009) 0.87
Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome. Am J Pathol (2013) 0.87
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A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum. PLoS One (2013) 0.82
Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease. Cell Tissue Res (2014) 0.82
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Human genetic disorders of sphingolipid biosynthesis. J Inherit Metab Dis (2014) 0.81
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Shiga toxins: intracellular trafficking to the ER leading to activation of host cell stress responses. Toxins (Basel) (2010) 0.80
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Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase. Glycoconj J (2011) 0.78
Distribution of Gb(3) Immunoreactivity in the Mouse Central Nervous System. Toxins (Basel) (2010) 0.78
TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide. Proc Natl Acad Sci U S A (2013) 0.78
Structural analysis of N-glycans from gull egg white glycoproteins and egg yolk IgG. Glycobiology (2009) 0.78
Structure-dependent pseudoreceptor intracellular traffic of adamantyl globotriaosyl ceramide mimics. J Biol Chem (2012) 0.78
Verotoxin-1 treatment or manipulation of its receptor globotriaosylceramide (gb3) for reversal of multidrug resistance to cancer chemotherapy. Toxins (Basel) (2010) 0.77
The consequences of genetic and pharmacologic reduction in sphingolipid synthesis. J Inherit Metab Dis (2014) 0.76
Investigation of encephalopathy caused by Shiga toxin 2c-producing Escherichia coli infection in mice. PLoS One (2013) 0.76
Current evidence for the role of complement in the pathogenesis of Shiga toxin haemolytic uraemic syndrome. Pediatr Nephrol (2013) 0.76
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro. Toxins (Basel) (2012) 0.76
Glycosphingolipid-Protein Interaction in Signal Transduction. Int J Mol Sci (2016) 0.75
Commensal E. coli Stx2 lysogens produce high levels of phages after spontaneous prophage induction. Front Cell Infect Microbiol (2015) 0.75
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Strong antibody reaction against glycosphingolipids injected in liposome-embedded forms in beta3GN-T5 knockout mice. Nagoya J Med Sci (2011) 0.75
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Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin. FEBS Open Bio (2015) 0.75
Immunization of A4galt-deficient mice with glycosphingolipids from renal cell cancers resulted in the generation of anti-sulfoglycolipid monoclonal antibodies. Glycoconj J (2016) 0.75
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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet (2008) 5.08
RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science (2005) 3.94
Developmental and species-divergent globin switching are driven by BCL11A. Nature (2009) 3.49
A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast. EMBO J (2004) 2.45
Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeres. Science (2008) 2.45
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. Mol Biol Cell (2007) 2.38
Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. Proc Natl Acad Sci U S A (2004) 2.16
An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo. Mol Endocrinol (2002) 2.08
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun (2008) 2.08
HIV-1 nef suppression by virally encoded microRNA. Retrovirology (2004) 2.05
Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol (2005) 2.02
Characterization of group C and G streptococcal strains that cause streptococcal toxic shock syndrome. J Clin Microbiol (2004) 2.00
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation (2004) 2.00
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. J Biol Chem (2004) 1.97
Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma. Cancer (2002) 1.94
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. Brain (2010) 1.90
Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air. Hum Mol Genet (2005) 1.76
Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property. Mol Cell Biol (2005) 1.67
MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression. J Biol Chem (2010) 1.66
Splicing factors facilitate RNAi-directed silencing in fission yeast. Science (2008) 1.65
O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors. J Biol Chem (2008) 1.65
Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency. Cardiovasc Res (2005) 1.63
Gonadal determination and adrenal development are regulated by the orphan nuclear receptor steroidogenic factor-1, in a dose-dependent manner. J Clin Endocrinol Metab (2002) 1.57
Inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells. Int J Urol (2011) 1.56
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neurosci Lett (2009) 1.54
Relationship of donor HLA antibody strength to the development of transfusion-related acute lung injury. Transfusion (2010) 1.53
A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells. Biochem Biophys Res Commun (2008) 1.52
Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres. Science (2009) 1.48
Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer. Oncogene (2003) 1.47
MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms. Prostate (2010) 1.44
O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions. Nat Commun (2011) 1.42
First detection of fosfomycin resistance gene fosA3 in CTX-M-producing Escherichia coli isolates from healthy individuals in Japan. Microb Drug Resist (2013) 1.41
The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin. EMBO J (2007) 1.40
A prospective evaluation of the effects of salpingectomy on endometrial lymphocyte clusters in patients with hydrosalpinges. Fertil Steril (2004) 1.39
b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve. J Biol Chem (2001) 1.38
Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene (2002) 1.37
Gangliosides contribute to stability of paranodal junctions and ion channel clusters in myelinated nerve fibers. Glia (2007) 1.36
Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. Eur J Immunol (2003) 1.35
Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria. J Biomed Sci (2002) 1.29
Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun (2009) 1.27
Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan. PLoS One (2008) 1.26
DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation. Genes Cells (2012) 1.26
Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy. Gastrointest Endosc (2005) 1.24
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C. J Biol Chem (2004) 1.23
Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction. Am J Pathol (2004) 1.22
Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo. J Biol Chem (2002) 1.21
Effect of antibiotics on group A Streptococcus exoprotein production analyzed by two-dimensional gel electrophoresis. Antimicrob Agents Chemother (2005) 1.21
O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1. Biochem Biophys Res Commun (2012) 1.21
The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY294002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells. Clin Cancer Res (2002) 1.20
Degradation of human Aurora-A protein kinase is mediated by hCdh1. FEBS Lett (2002) 1.20
Gene amplification and overexpression of PRDM14 in breast cancers. Cancer Res (2007) 1.18
Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast. EMBO Rep (2010) 1.17
GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia. Eur J Pediatr (2012) 1.17
CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis. J Immunol (2010) 1.16
Mitochondrial genome polymorphisms associated with type-2 diabetes or obesity. Mitochondrion (2005) 1.14
Analysis of the role of Aurora B on the chromosomal targeting of condensin I. Nucleic Acids Res (2007) 1.14
Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome. Infect Immun (2002) 1.13
Enrichment of longevity phenotype in mtDNA haplogroups D4b2b, D4a, and D5 in the Japanese population. Hum Genet (2007) 1.12
Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10. Mol Cell Biol (2006) 1.12
Guillain-Barré syndrome associated with normal or exaggerated tendon reflexes. J Neurol (2011) 1.12
Women with mitochondrial haplogroup N9a are protected against metabolic syndrome. Diabetes (2007) 1.11
Immunologic glycosphingolipidomics and NKT cell development in mouse thymus. J Proteome Res (2009) 1.11
A long-term study of sharps injuries among health care workers in Japan. Am J Infect Control (2007) 1.11
Involvement of surface polysaccharides in the organic acid resistance of Shiga Toxin-producing Escherichia coli O157:H7. Mol Microbiol (2002) 1.10
Nucleophosmin: a versatile molecule associated with hematological malignancies. Cancer Sci (2006) 1.09
Loss of CpG methylation is strongly correlated with loss of histone H3 lysine 9 methylation at DMR-LIT1 in patients with Beckwith-Wiedemann syndrome. Am J Hum Genet (2003) 1.09
MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase. J Biol Chem (2002) 1.08
Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells. Carcinogenesis (2009) 1.08
Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "Klotho" mouse. Semin Thromb Hemost (2002) 1.07
Cytomegalovirus infection in severe ulcerative colitis patients undergoing continuous intravenous cyclosporine treatment in Japan. World J Gastroenterol (2007) 1.06
GnRH regulates early growth response protein 1 transcription through multiple promoter elements. Mol Endocrinol (2002) 1.06
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. Biochem Biophys Res Commun (2009) 1.06
Silencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer. Oncogene (2004) 1.06
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A (2005) 1.06
Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. J Neurosci (2002) 1.05
Similarity of tetracycline resistance genes isolated from fish farm bacteria to those from clinical isolates. Appl Environ Microbiol (2003) 1.05
Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells. Oncogene (2004) 1.04
TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness. Pain (2008) 1.04
Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis. J Biol Chem (2005) 1.04
Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma. Clin Cancer Res (2002) 1.04