Published in J Exp Med on February 13, 2006
A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis. Arthritis Res Ther (2012) 1.17
Recent developments in the immunobiology of rheumatoid arthritis. Arthritis Res Ther (2008) 1.14
The effect of targeted rheumatoid arthritis therapies on anti-citrullinated protein autoantibody levels and B cell responses. Clin Exp Immunol (2013) 0.93
Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo. J Immunol (2010) 0.91
Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome. Pain (2014) 0.90
Cells of the synovium in rheumatoid arthritis. B cells. Arthritis Res Ther (2007) 0.85
Inhibitors of the FcRn:IgG protein-protein interaction. AAPS J (2009) 0.83
Targeting FcRn for the modulation of antibody dynamics. Mol Immunol (2015) 0.80
Clinical approaches to early inflammatory arthritis. Nat Rev Rheumatol (2009) 0.80
KRN/I-Ag7 mouse arthritis is independent of complement C3. J Clin Immunol (2011) 0.79
Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis? Arthritis Res Ther (2010) 0.78
On the perplexingly low rate of transport of IgG2 across the human placenta. PLoS One (2014) 0.77
Genetically engineered humanized mouse models for preclinical antibody studies. BioDrugs (2014) 0.77
Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals. PLoS One (2014) 0.75
Update on the use of rituximab for intractable rheumatoid arthritis. Open Access Rheumatol (2009) 0.75
Gammaglobulins, autoantibodies, therapeutic antibodies and anti-drug antibodies in rheumatoid arthritis. Clin Exp Immunol (2014) 0.75
Activating and inhibitory Fc gamma receptors in rheumatoid arthritis: from treatment to targeted therapies. Arthritis Res Ther (2007) 0.75
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum (1988) 111.05
IgG Fc receptors. Annu Rev Immunol (2001) 8.63
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest (1998) 6.92
Organ-specific disease provoked by systemic autoimmunity. Cell (1996) 6.44
Rheumatoid arthritis. Cell (1996) 6.01
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity (1999) 5.38
Arthritis critically dependent on innate immune system players. Immunity (2002) 5.31
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset. Arthritis Res (2000) 3.03
Induction of arthritis with monoclonal antibodies to collagen. J Immunol (1992) 2.64
Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin. Arthritis Res Ther (2004) 2.58
The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat Immunol (2004) 1.95
Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritis. J Exp Med (1999) 1.92
The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis. J Immunol (2002) 1.70
Dynamic visualization of a joint-specific autoimmune response through positron emission tomography. Nat Immunol (2002) 1.68
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease. J Clin Invest (2004) 1.59
Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis Rheum (2003) 1.41
Passive transfer of arthritis to mice by injection of human anti-type II collagen antibody. Mayo Clin Proc (1984) 1.37
Rheumatoid factor revisited. Curr Opin Rheumatol (2004) 1.33
Examination of synovial fluid as a diagnostic aid in arthritis. Med Clin North Am (1966) 1.17
Transfusion studies in rheumatoid arthritis. Arthritis Rheum (1961) 1.15
Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis. Ann Rheum Dis (2004) 0.89
A critical role for Fc gamma RIIB in the induction of rheumatoid factors. J Immunol (2004) 0.82
Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol (2005) 9.76
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J Immunol (2004) 4.43
International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. Ann Rheum Dis (2013) 3.99
The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs. J Immunol (2003) 3.09
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity (2004) 2.79
The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan. J Exp Med (2003) 2.63
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc Natl Acad Sci U S A (2009) 2.46
Enhanced antibody half-life improves in vivo activity. Nat Biotechnol (2010) 2.33
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease. Int Immunol (2006) 2.32
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. J Clin Invest (2006) 2.16
Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection. Proc Natl Acad Sci U S A (2011) 2.14
Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci U S A (2008) 2.12
Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism. J Immunol (2007) 1.86
Dependence of antibody-mediated presentation of antigen on FcRn. Proc Natl Acad Sci U S A (2008) 1.82
In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J Exp Med (2006) 1.79
The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease. J Clin Invest (2004) 1.59
Albumin turnover: FcRn-mediated recycling saves as much albumin from degradation as the liver produces. Am J Physiol Gastrointest Liver Physiol (2005) 1.59
Efficient mucosal vaccination mediated by the neonatal Fc receptor. Nat Biotechnol (2011) 1.47
Immunodominance of H60 is caused by an abnormally high precursor T cell pool directed against its unique minor histocompatibility antigen peptide. Immunity (2002) 1.47
CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice. Proc Natl Acad Sci U S A (2011) 1.41
Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural T(iNKT) cell receptor [corrected]. J Immunol (2003) 1.38
Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases. J Clin Invest (2005) 1.36
Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature. Invest Ophthalmol Vis Sci (2005) 1.31
Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease. Blood (2002) 1.23
Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Huët anomaly. Hum Mol Genet (2003) 1.22
T cell knockout mice have diminished alveolar bone loss after oral infection with Porphyromonas gingivalis. FEMS Immunol Med Microbiol (2002) 1.16
Mutations in sterol O-acyltransferase 1 (Soat1) result in hair interior defects in AKR/J mice. J Invest Dermatol (2010) 1.15
NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences. J Immunol (2007) 1.14
Glomerulonephritis causing acute renal failure during the course of bacterial infections. Histological varieties, potential pathogenetic pathways and treatment. Int Urol Nephrol (2008) 1.14
Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages. Physiol Genomics (2008) 1.10
Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies. Methods Mol Biol (2010) 1.09
A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection. J Virol (2011) 1.06
Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. Clin Immunol (2004) 1.04
The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells. J Immunol (2011) 0.99
A mouse model of generalized non-Herlitz junctional epidermolysis bullosa. J Invest Dermatol (2010) 0.99
NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas. Cancer Res (2008) 0.98
ExQuest, a novel method for displaying quantitative gene expression from ESTs. Genomics (2004) 0.97
Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport. Proc Natl Acad Sci U S A (2011) 0.97
Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late-stage differentiation of normal B cells. Cancer Res (2007) 0.97
The Tetratricopeptide repeat domain 7 gene is mutated in flaky skin mice: a model for psoriasis, autoimmunity, and anemia. Exp Biol Med (Maywood) (2005) 0.95
IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R. Blood (2013) 0.94
Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood) (2003) 0.93
Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity. Inflamm Bowel Dis (2010) 0.93
Coronary artery disease from isolated non-H2-determined incompatibilities in transplanted mouse hearts. Transplantation (2011) 0.91
Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. J Biol Chem (2012) 0.90
Increased expression of Cxcr3 and its ligands, Cxcl9 and Cxcl10, during the development of alopecia areata in the mouse. J Invest Dermatol (2012) 0.90
Cutting edge: the minor histocompatibility antigen H60 peptide interacts with both H-2Kb and NKG2D. J Immunol (2002) 0.89
Clinical chemistry of human FcRn transgenic mice. Mamm Genome (2011) 0.88
Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in Fasl. J Exp Med (2004) 0.88
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis. J Immunol (2011) 0.87
Genetic susceptibility to chronic periodontal disease. Microbes Infect (2002) 0.87
Searching QTL by gene expression: analysis of diabesity. BMC Genet (2005) 0.87
Expression of neonatal Fc receptor in the eye. Invest Ophthalmol Vis Sci (2014) 0.87
Establishment and characterization of a new osteogenic cell line (MOS-J) from a spontaneous C57BL/6J mouse osteosarcoma. In Vivo (2002) 0.86
The Cinderella effect: searching for the best fit between mouse models and human diseases. J Invest Dermatol (2013) 0.85
Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5. Genomics (2003) 0.85
The H4b minor histocompatibility antigen is caused by a combination of genetically determined and posttranslational modifications. J Immunol (2003) 0.85
Duration of alloantigen presentation and avidity of T cell antigen recognition correlate with immunodominance of CTL response to minor histocompatibility antigens. J Immunol (2004) 0.84
A direct method to determine the strength of the dermal-epidermal junction in a mouse model for epidermolysis bullosa. Exp Dermatol (2012) 0.83
Molecular mechanisms of induction of antigen-specific allograft tolerance by intranasal peptide administration. J Immunol (2011) 0.83
IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice. J Immunol (2013) 0.83
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A (2011) 0.82
A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen. Immunogenetics (2003) 0.80
The MHC class I-related FcRn ameliorates murine Lyme arthritis. Int Immunol (2006) 0.80
Survival and function of MiHA epitope-specific host CD8 TM cells following ablative conditioning and HCT. Biol Blood Marrow Transplant (2007) 0.80
Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs. MAbs (2015) 0.80
B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection. Interdiscip Perspect Infect Dis (2009) 0.77
Generation and characterization of a novel tetravalent anti-CD22 antibody with improved antitumor activity and pharmacokinetics. Int Immunopharmacol (2005) 0.77
A single-amino-acid variant of the H60 CD8 epitope generates specific immunity with diverse TCR recruitment. Mol Cells (2012) 0.77
An immunodominant minor histocompatibility alloantigen that initiates corneal allograft rejection. Transplantation (2003) 0.77
Genetically engineered humanized mouse models for preclinical antibody studies. BioDrugs (2014) 0.77
A mouse model of heritable cerebrovascular disease. PLoS One (2010) 0.76
Electrochemical biosensor for quantitation of anti-DNA autoantibodies in human serum. Biosens Bioelectron (2013) 0.76
Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice. J Autoimmun (2002) 0.75
Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice. PLoS One (2013) 0.75
Tumoral calcinosis without hyperparathyroidism in a patient on continuous ambulatory peritoneal dialysis. Adv Perit Dial (2008) 0.75
Was there type 1 diabetes in the Olduvai Gorge? Adv Exp Med Biol (2004) 0.75
Twenty-first Century ethics of medical research involving human subjects: achievements and challenges. Int Urol Nephrol (2008) 0.75