PubRank

David J Mooney

Author PubWeight™ 220.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Growth factors, matrices, and forces combine and control stem cells. Science 2009 8.46
2 Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 2003 7.15
3 Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nat Mater 2010 5.36
4 Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med 2006 5.10
5 Engineering tumors with 3D scaffolds. Nat Methods 2007 3.96
6 Highly stretchable and tough hydrogels. Nature 2012 3.34
7 Alginate: properties and biomedical applications. Prog Polym Sci 2012 3.18
8 Alginate hydrogels as biomaterials. Macromol Biosci 2006 2.94
9 Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface 2010 2.69
10 Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors. Proc Natl Acad Sci U S A 2009 2.29
11 Inspiration and application in the evolution of biomaterials. Nature 2009 2.23
12 Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol 2012 2.17
13 FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness. Proc Natl Acad Sci U S A 2005 2.07
14 Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement. Proc Natl Acad Sci U S A 2009 2.07
15 Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells. Bone 2004 2.05
16 Alginate type and RGD density control myoblast phenotype. J Biomed Mater Res 2002 2.04
17 Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res 2006 2.03
18 Infection-mimicking materials to program dendritic cells in situ. Nat Mater 2009 2.00
19 Material-based deployment enhances efficacy of endothelial progenitor cells. Proc Natl Acad Sci U S A 2008 1.96
20 Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. Biomaterials 2006 1.88
21 Combined angiogenic and osteogenic factor delivery enhances bone marrow stromal cell-driven bone regeneration. J Bone Miner Res 2004 1.83
22 Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater 2005 1.83
23 Label-free biomarker detection from whole blood. Nat Nanotechnol 2009 1.80
24 Endothelial cell modulation of bone marrow stromal cell osteogenic potential. FASEB J 2005 1.79
25 Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction. Cardiovasc Res 2007 1.77
26 Engineering growing tissues. Proc Natl Acad Sci U S A 2002 1.76
27 Polymeric growth factor delivery strategies for tissue engineering. Pharm Res 2003 1.74
28 Controlling alginate gel degradation utilizing partial oxidation and bimodal molecular weight distribution. Biomaterials 2005 1.74
29 New materials for tissue engineering: towards greater control over the biological response. Trends Biotechnol 2008 1.69
30 In situ regulation of DC subsets and T cells mediates tumor regression in mice. Sci Transl Med 2009 1.65
31 Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 2007 1.64
32 Controlled growth factor delivery for tissue engineering. Adv Mater 2009 1.63
33 VEGF scaffolds enhance angiogenesis and bone regeneration in irradiated osseous defects. J Bone Miner Res 2006 1.63
34 Engineering vascular networks in porous polymer matrices. J Biomed Mater Res 2002 1.60
35 Active scaffolds for on-demand drug and cell delivery. Proc Natl Acad Sci U S A 2010 1.58
36 The tensile properties of alginate hydrogels. Biomaterials 2004 1.57
37 Cyclic strain enhances matrix mineralization by adult human mesenchymal stem cells via the extracellular signal-regulated kinase (ERK1/2) signaling pathway. J Biomech 2003 1.56
38 Bioinspired growth of crystalline carbonate apatite on biodegradable polymer substrata. J Am Chem Soc 2002 1.51
39 Regulating activation of transplanted cells controls tissue regeneration. Proc Natl Acad Sci U S A 2006 1.46
40 Controlling rigidity and degradation of alginate hydrogels via molecular weight distribution. Biomacromolecules 2004 1.44
41 Sustained vascular endothelial growth factor delivery enhances angiogenesis and perfusion in ischemic hind limb. Pharm Res 2005 1.43
42 An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Biomaterials 2010 1.42
43 Regulating myoblast phenotype through controlled gel stiffness and degradation. Tissue Eng 2007 1.40
44 Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells. Tissue Eng 2003 1.39
45 Designing alginate hydrogels to maintain viability of immobilized cells. Biomaterials 2003 1.39
46 NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation. Proc Natl Acad Sci U S A 2013 1.35
47 Integrated approach to designing growth factor delivery systems. FASEB J 2007 1.35
48 Effects of a bone-like mineral film on phenotype of adult human mesenchymal stem cells in vitro. Biomaterials 2005 1.34
49 Quantifying the relation between adhesion ligand-receptor bond formation and cell phenotype. Proc Natl Acad Sci U S A 2006 1.34
50 Differentiation stage alters matrix control of stem cells. J Biomed Mater Res A 2008 1.33
51 Salt fusion: an approach to improve pore interconnectivity within tissue engineering scaffolds. Tissue Eng 2002 1.33
52 Can tissue engineering concepts advance tumor biology research? Trends Biotechnol 2010 1.32
53 Effects of VEGF temporal and spatial presentation on angiogenesis. Biomaterials 2009 1.32
54 Injectable preformed scaffolds with shape-memory properties. Proc Natl Acad Sci U S A 2012 1.28
55 Effect of substrate mechanics on chondrocyte adhesion to modified alginate surfaces. Arch Biochem Biophys 2004 1.26
56 Mechanical strain regulates endothelial cell patterning in vitro. Tissue Eng 2007 1.26
57 Macroscale delivery systems for molecular and cellular payloads. Nat Mater 2013 1.25
58 Temporally regulated delivery of VEGF in vitro and in vivo. J Biomed Mater Res A 2006 1.23
59 Polymers to direct cell fate by controlling the microenvironment. Curr Opin Biotechnol 2007 1.20
60 Polymers for pro- and anti-angiogenic therapy. Biomaterials 2007 1.19
61 Protein-based signaling systems in tissue engineering. Curr Opin Biotechnol 2003 1.16
62 Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: a combined computational and experimental approach. Biomaterials 2007 1.16
63 Fabrication and in vitro testing of polymeric delivery system for condensed DNA. J Biomed Mater Res A 2003 1.15
64 Long-term in vivo gene expression via delivery of PEI-DNA condensates from porous polymer scaffolds. Hum Gene Ther 2005 1.15
65 Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors. Biomaterials 2013 1.14
66 A bioinspired soft actuated material. Adv Mater 2013 1.14
67 Sustained delivery of plasmid DNA from polymeric scaffolds for tissue engineering. Adv Drug Deliv Rev 2006 1.13
68 In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles. Nat Commun 2013 1.11
69 Locally enhanced angiogenesis promotes transplanted cell survival. Tissue Eng 2004 1.10
70 Design of biodegradable hydrogel for the local and sustained delivery of angiogenic plasmid DNA. Pharm Res 2008 1.10
71 Microenvironmental regulation of biomacromolecular therapies. Nat Rev Drug Discov 2007 1.10
72 The role of multifunctional delivery scaffold in the ability of cultured myoblasts to promote muscle regeneration. Biomaterials 2011 1.09
73 Cyclic arginine-glycine-aspartate peptides enhance three-dimensional stem cell osteogenic differentiation. Tissue Eng Part A 2009 1.09
74 Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects. Bone 2011 1.09
75 Designing scaffolds to enhance transplanted myoblast survival and migration. Tissue Eng 2006 1.09
76 Nanoscale cell adhesion ligand presentation regulates nonviral gene delivery and expression. Nano Lett 2007 1.09
77 Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Nano Lett 2010 1.08
78 The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials 2008 1.07
79 Biomaterial delivery of morphogens to mimic the natural healing cascade in bone. Adv Drug Deliv Rev 2012 1.07
80 Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis. Pharm Res 2009 1.07
81 Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci U S A 2009 1.06
82 Stress-relaxation behavior in gels with ionic and covalent crosslinks. J Appl Phys 2010 1.06
83 Shape-defining scaffolds for minimally invasive tissue engineering. Transplantation 2004 1.04
84 Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants. Cancer Res 2014 1.04
85 Comparison of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in SCID mice. J Control Release 2003 1.03
86 Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev 2007 1.03
87 Tissue engineering strategies for in vivo neovascularisation. Expert Opin Biol Ther 2002 1.02
88 External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly. Am J Physiol Cell Physiol 2002 1.02
89 Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix. Biomaterials 2007 1.01
90 Noninvasive probing of the spatial organization of polymer chains in hydrogels using fluorescence resonance energy transfer (FRET). J Am Chem Soc 2007 1.01
91 Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. Biomaterials 2009 1.00
92 Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci U S A 2010 1.00
93 Performance and biocompatibility of extremely tough alginate/polyacrylamide hydrogels. Biomaterials 2013 1.00
94 Improved bone healing by angiogenic factor-enriched platelet-rich plasma and its synergistic enhancement by bone morphogenetic protein-2. Int J Oral Maxillofac Implants 2008 0.97
95 Controlled architectural and chemotactic studies of 3D cell migration. Biomaterials 2011 0.97
96 Integrin-adhesion ligand bond formation of preosteoblasts and stem cells in three-dimensional RGD presenting matrices. Biomacromolecules 2008 0.97
97 Multi-scale modeling to predict ligand presentation within RGD nanopatterned hydrogels. Biomaterials 2005 0.96
98 Fluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensions. Biomaterials 2007 0.96
99 Regeneration of vascularized bone. Periodontol 2000 2006 0.95
100 Shape retaining injectable hydrogels for minimally invasive bulking. J Urol 2004 0.93
101 Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering. J Biomed Mater Res A 2003 0.92
102 Materials based tumor immunotherapy vaccines. Curr Opin Immunol 2013 0.92
103 Stem-cell differentiation: Anchoring cell-fate cues. Nat Mater 2012 0.91
104 Cyclic strain inhibits switching of smooth muscle cells to an osteoblast-like phenotype. FASEB J 2003 0.91
105 Biomaterial-based vaccine induces regression of established intracranial glioma in rats. Pharm Res 2011 0.91
106 Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA. Cell Res 2013 0.90
107 Viability and functionality of cells delivered from peptide conjugated scaffolds. Biomaterials 2011 0.89
108 Regenerative medicine in orthopaedic surgery. J Orthop Res 2007 0.89
109 Controlled degradation of hydrogels using multi-functional cross-linking molecules. Biomaterials 2004 0.89
110 Hypoxia leads to necrotic hepatocyte death. J Biomed Mater Res A 2007 0.89
111 Cellular cross-linking of peptide modified hydrogels. J Biomech Eng 2005 0.89
112 Modifying the proliferative state of target cells to control DNA expression and identifying cell types transfected in vivo. Mol Ther 2007 0.89
113 Synthetic extracellular matrices for tissue engineering and regeneration. Curr Top Dev Biol 2004 0.89
114 Regulation of chondrocyte differentiation level via co-culture with osteoblasts. Tissue Eng 2006 0.89
115 Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells. J Biomech 2004 0.89
116 Influence of flow conditions and matrix coatings on growth and differentiation of three-dimensionally cultured rat hepatocytes. Tissue Eng 2004 0.88
117 Externally applied cyclic strain regulates localization of focal contact components in cultured smooth muscle cells. Ann Biomed Eng 2002 0.88
118 In Vivo Modulation of Dendritic Cells by Engineered Materials: Towards New Cancer Vaccines. Nano Today 2011 0.88
119 Bioactive cell-hydrogel microcapsules for cell-based drug delivery. J Control Release 2009 0.88
120 Modulating Notch signaling to enhance neovascularization and reperfusion in diabetic mice. Biomaterials 2010 0.88
121 Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device. Biomed Microdevices 2010 0.87
122 Guided bone regeneration using injectable vascular endothelial growth factor delivery gel. J Periodontol 2012 0.86
123 Host immune competence and local ischemia affects the functionality of engineered vasculature. Microcirculation 2007 0.86
124 Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease. Neurotox Res 2009 0.85
125 Sustained GM-CSF and PEI condensed pDNA presentation increases the level and duration of gene expression in dendritic cells. J Control Release 2008 0.85
126 Biphasic ferrogels for triggered drug and cell delivery. Adv Healthc Mater 2014 0.85
127 Tissue engineering: a glue for biomaterials. Nat Mater 2007 0.84
128 TGF-ß regulates enamel mineralization and maturation through KLK4 expression. PLoS One 2013 0.84
129 Bone engineering by controlled delivery of osteoinductive molecules and cells. Expert Opin Biol Ther 2004 0.84
130 Surface modification with alginate-derived polymers for stable, protein-repellent, long-circulating gold nanoparticles. ACS Nano 2012 0.84
131 Ca(2+) released from calcium alginate gels can promote inflammatory responses in vitro and in vivo. Acta Biomater 2013 0.84
132 Presentation of BMP-2 mimicking peptides in 3D hydrogels directs cell fate commitment in osteoblasts and mesenchymal stem cells. Biomacromolecules 2014 0.83
133 Immunologically active biomaterials for cancer therapy. Curr Top Microbiol Immunol 2011 0.83
134 Adipose tissue engineering using injectable, oxidized alginate hydrogels. Tissue Eng Part A 2012 0.83
135 Cell mediated contraction in 3D cell-matrix constructs leads to spatially regulated osteogenic differentiation. Integr Biol (Camb) 2013 0.83
136 Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines. Biomatter 2013 0.82
137 Quantifying the relation between bond number and myoblast proliferation. Faraday Discuss 2008 0.81
138 Three-dimensional human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Eng Part C Methods 2015 0.81
139 Delivery of hepatotrophic factors fails to enhance longer-term survival of subcutaneously transplanted hepatocytes. Tissue Eng 2006 0.81
140 Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts. Epigenetics 2014 0.81
141 Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method. Biotechniques 2007 0.81
142 Evaluation of chain stiffness of partially oxidized polyguluronate. Biomacromolecules 2002 0.81
143 Shear-reversibly crosslinked alginate hydrogels for tissue engineering. Macromol Biosci 2009 0.81
144 The effects of poly(ethyleneimine) (PEI) molecular weight on reinforcement of alginate hydrogels. Cell Transplant 2003 0.81
145 Rescue of SCID murine ischemic hindlimbs with pH-modified rhbFGF/poly(DL-lactic-co-glycolic acid) implants. J Control Release 2007 0.80
146 Molecular-scale biomimicry. Nat Biotechnol 2002 0.80
147 Cell-friendly inverse opal-like hydrogels for a spatially separated co-culture system. Macromol Rapid Commun 2014 0.80
148 Endothelial cells expressing low levels of CD143 (ACE) exhibit enhanced sprouting and potency in relieving tissue ischemia. Angiogenesis 2014 0.80
149 Role of poly(lactide-co-glycolide) particle size on gas-foamed scaffolds. J Biomater Sci Polym Ed 2004 0.79
150 Linear patterning of mesenchymal condensations is modulated by geometric constraints. J R Soc Interface 2014 0.79
151 Cellular strain assessment tool (CSAT): precision-controlled cyclic uniaxial tensile loading. J Biomech 2009 0.79
152 Optimizing siRNA efficacy through alteration in the target cell-adhesion substrate interaction. J Biomed Mater Res A 2012 0.79
153 The efficacy of intracranial PLG-based vaccines is dependent on direct implantation into brain tissue. J Control Release 2011 0.79
154 Injectable MMP-sensitive alginate hydrogels as hMSC delivery systems. Biomacromolecules 2013 0.79
155 Growth of human blood vessels in severe combined immunodeficient mice. A new in vivo model system of angiogenesis. Methods Mol Med 2003 0.79
156 Quantifying interactions between cell receptors and adhesion ligand-modified polymers in solution. Macromol Biosci 2008 0.79
157 Soft nanofluidics governing minority ion exclusion in charged hydrogels. Soft Matter 2015 0.78
158 Effect of pore structure of macroporous poly(lactide-co-glycolide) scaffolds on the in vivo enrichment of dendritic cells. ACS Appl Mater Interfaces 2014 0.78
159 Polycation structure mediates expression of lyophilized polycation/pDNA complexes. Macromol Biosci 2010 0.78
160 In vivo targeting through click chemistry. ChemMedChem 2015 0.78
161 Tracheal reconstruction using tissue-engineered cartilage. Arch Otolaryngol Head Neck Surg 2004 0.78
162 Cell instructive polymers. Adv Biochem Eng Biotechnol 2006 0.78
163 Spatiotemporal control over molecular delivery and cellular encapsulation from electropolymerized micro- and nanopatterned surfaces. Adv Funct Mater 2009 0.77
164 Quantification of fibronectin adsorption to silicone-rubber cell culture substrates. Biotechniques 2002 0.77
165 A compressible scaffold for minimally invasive delivery of large intact neuronal networks. Adv Healthc Mater 2014 0.77
166 Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia. Tissue Eng Part A 2015 0.77
167 The Combination of Vascular Endothelial Growth Factor and Stromal Cell-Derived Factor Induces Superior Angiogenic Sprouting by Outgrowth Endothelial Cells. J Vasc Res 2015 0.77
168 Statistical platform to discern spatial and temporal coordination of endothelial sprouting. Integr Biol (Camb) 2012 0.76
169 Study on the potential of RGD- and PHSRN-modified alginates as artificial extracellular matrices for engineering bone. J Artif Organs 2013 0.76
170 Synthetic extracellular matrices for tissue engineering. Pharm Res 2008 0.76
171 [Cell-traction mediated configuration of the cell/extracellular-matrix interface plays a key role in stem cell fate]. Med Sci (Paris) 2011 0.76
172 Manipulating the intersection of angiogenesis and inflammation. Ann Biomed Eng 2014 0.75
173 A biomimetic approach for the creation of two-dimensional microscale surface patterns: creation of isolated immunological synapses. Int J Biomater 2009 0.75
174 AFM imaging of RGD presenting synthetic extracellular matrix using gold nanoparticles. Macromol Biosci 2008 0.75
175 Metal-enhanced fluorescence to quantify bacterial adhesion. Adv Mater 2011 0.75
176 VEGF and IGF Delivered from Alginate Hydrogels Promote Stable Perfusion Recovery in Ischemic Hind Limbs of Aged Mice and Young Rabbits. J Vasc Res 2017 0.75
177 Controlled self-assembly of alginate microgels by rapidly binding molecule pairs. Lab Chip 2017 0.75
178 Selective adipose tissue ablation by localized, sustained drug delivery. Plast Reconstr Surg 2003 0.75
179 13. From tissue engineering to therapeutic cancer vaccines: Original research article: Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery, 2000. J Control Release 2014 0.75