Joerg R Weber

Author PubWeight™ 31.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved. J Biol Chem 2003 3.13
2 Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J Clin Invest 2002 2.50
3 A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci 2008 1.85
4 Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia. J Neuroimmunol 2007 1.85
5 A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia. J Immunol 2006 1.76
6 Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology. J Immunol 2006 1.37
7 The role of lipopolysaccharide-binding protein in modulating the innate immune response. Microbes Infect 2006 1.32
8 Bacterial programmed cell death of cerebral endothelial cells involves dual death pathways. J Clin Invest 2005 1.32
9 TLR2 mediates neuroinflammation and neuronal damage. J Immunol 2007 1.26
10 Timing the valve replacement in infective endocarditis involving the brain. J Neurol 2004 1.23
11 Triptans reduce the inflammatory response in bacterial meningitis. J Cereb Blood Flow Metab 2002 1.20
12 Dual phases of apoptosis in pneumococcal meningitis. J Infect Dis 2004 1.11
13 Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. Eur J Neurosci 2002 1.09
14 Pneumolysin causes neuronal cell death through mitochondrial damage. Infect Immun 2007 1.07
15 TRAIL limits excessive host immune responses in bacterial meningitis. J Clin Invest 2007 1.05
16 Interplay of pneumococcal hydrogen peroxide and host-derived nitric oxide. Infect Immun 2006 1.00
17 TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia. J Immunol 2007 0.97
18 Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain. J Exp Med 2004 0.92
19 Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in central nervous system inflammation. J Mol Med (Berl) 2009 0.90
20 Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis 2010 0.89
21 Pneumococcal cell wall-induced meningitis impairs adult hippocampal neurogenesis. Infect Immun 2007 0.83
22 Bacterial hydrogen peroxide contributes to cerebral hyperemia during early stages of experimental pneumococcal meningitis. J Cereb Blood Flow Metab 2007 0.83
23 The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level. J Neurochem 2004 0.77
24 Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infect Immun 2004 0.75
25 Heterogeneous effects of distinct tocopherol analogues on NO release, cell volume, and cell death in microglial cells. J Neurosci Res 2008 0.75