Published in Infect Immun on June 25, 2007
Microglia development and function. Annu Rev Immunol (2014) 1.41
Pre-infection physical exercise decreases mortality and stimulates neurogenesis in bacterial meningitis. J Neuroinflammation (2012) 0.80
Bacterial Peptidoglycan Transverses the Placenta to Induce Fetal Neuroproliferation and Aberrant Postnatal Behavior. Cell Host Microbe (2016) 0.78
Thrombopoietin contributes to neuronal damage in experimental bacterial meningitis. Infect Immun (2010) 0.76
Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. Antimicrob Agents Chemother (2016) 0.75
Bacterial meningitis complicating the course of liver cirrhosis. Infection (2017) 0.75
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci (1999) 12.50
Inflammatory blockade restores adult hippocampal neurogenesis. Science (2003) 10.14
More hippocampal neurons in adult mice living in an enriched environment. Nature (1997) 10.06
Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol (1999) 6.60
Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci (1997) 5.78
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc Natl Acad Sci U S A (2003) 5.11
Inflammation is detrimental for neurogenesis in adult brain. Proc Natl Acad Sci U S A (2003) 5.09
Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell (2002) 4.87
Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A (2001) 4.36
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med (2000) 4.18
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci U S A (1998) 4.14
The induction of meningeal inflammation by components of the pneumococcal cell wall. J Infect Dis (1985) 3.66
Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J Neurosci (1998) 3.20
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J Clin Invest (2002) 2.50
Structure of the peptide network of pneumococcal peptidoglycan. J Biol Chem (1987) 2.45
The relative role of bacterial cell wall and capsule in the induction of inflammation in pneumococcal meningitis. J Infect Dis (1985) 2.34
L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem (1994) 2.13
Effects of ampicillin and corticosteroids on brain water content, cerebrospinal fluid pressure, and cerebrospinal fluid lactate levels in experimental pneumococcal meningitis. J Infect Dis (1985) 2.10
Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol Cell Neurosci (2003) 1.94
Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis. J Neurosci (2006) 1.91
FGF-2 regulation of neurogenesis in adult hippocampus after brain injury. Proc Natl Acad Sci U S A (2001) 1.90
Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells. Nature (1995) 1.85
Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury. J Neurosci Res (2001) 1.82
Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein. Immunity (2003) 1.81
Nitric oxide and the regulation of gene expression. Trends Cell Biol (2001) 1.76
Surface components of Streptococcus pneumoniae. Rev Infect Dis (1981) 1.69
In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci U S A (2000) 1.67
Cerebrospinal fluid outflow resistance in rabbits with experimental meningitis. Alterations with penicillin and methylprednisolone. J Clin Invest (1980) 1.64
Nitric oxide negatively regulates mammalian adult neurogenesis. Proc Natl Acad Sci U S A (2003) 1.42
Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus. Eur J Neurosci (2005) 1.39
Apoptosis of neurons in the dentate gyrus in humans suffering from bacterial meningitis. J Neuropathol Exp Neurol (1999) 1.38
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest (2003) 1.24
Triptans reduce the inflammatory response in bacterial meningitis. J Cereb Blood Flow Metab (2002) 1.20
Production and release of peptidoglycan and wall teichoic acid polymers in pneumococci treated with beta-lactam antibiotics. J Bacteriol (1984) 1.17
A novel, nerve growth factor-activated pathway involving nitric oxide, p53, and p21WAF1 regulates neuronal differentiation of PC12 cells. J Biol Chem (1997) 1.16
Nitric oxide and Drosophila development. Cell Death Differ (1999) 1.14
Dual phases of apoptosis in pneumococcal meningitis. J Infect Dis (2004) 1.11
Pneumococcal meningitis. Late neurologic sequelae and features of prognostic impact. Arch Neurol (1984) 1.06
Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations. Neurology (1999) 1.04
Nitric oxide is an essential negative regulator of cell proliferation in Xenopus brain. J Neurosci (2001) 1.04
Modulation of renal disease in MRL/lpr mice by pharmacologic inhibition of inducible nitric oxide synthase. Kidney Int (2002) 1.01
Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. J Infect Dis (1998) 0.99
Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis. Brain Res (1996) 0.96
Regulation of neuronal proliferation and differentiation by nitric oxide. Mol Neurobiol (2003) 0.95
Differential expression of nitric oxide synthases in bacterial meningitis: role of the inducible isoform for blood-brain barrier breakdown. J Infect Dis (2001) 0.94
Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats. Dev Neurosci (2007) 0.89
Effects of cyclooxygenase inhibitor pretreatment on nitric oxide production, nNOS and iNOS expression in rat cerebellum. Br J Pharmacol (2003) 0.89
Ecdysteroid coordinates optic lobe neurogenesis via a nitric oxide signaling pathway. Development (2000) 0.89
Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. J Neuropathol Exp Neurol (2005) 0.88
Increased neurogenesis after experimental Streptococcus pneumoniae meningitis. J Neurosci Res (2003) 0.85
Transient overexpression of the 5-HT1A receptor impairs water-maze but not hole-board performance. Neurobiol Learn Mem (2005) 0.83
Direct evidence of in vivo nitric oxide production and inducible nitric oxide synthase mRNA expression in the brain of living rat during experimental meningitis. J Cereb Blood Flow Metab (1999) 0.82
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma. J Leukoc Biol (2000) 0.82
Down-regulation of mouse organic anion-transporting polypeptide 4 (Oatp4; Oatp1b2; Slc21a10) mRNA by lipopolysaccharide through the toll-like receptor 4 (TLR4). Drug Metab Dispos (2004) 0.82
Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental meningitis in the rat. Eur J Pharmacol (1995) 0.78
Application of 'nose-poke habituation' validation with post-trial diazepam- and cholecystokinin-induced hypo- and hypermnesia. J Neurosci Methods (1995) 0.77
Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science (2003) 4.58
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J Clin Invest (2002) 2.50
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. PLoS Biol (2009) 2.40
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci (2002) 2.05
A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci (2008) 1.85
Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia. J Neuroimmunol (2007) 1.85
Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein. Immunity (2003) 1.81
A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia. J Immunol (2006) 1.76
Sugammadex and neostigmine dose-finding study for reversal of shallow residual neuromuscular block. Anesthesiology (2010) 1.55
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46
Roller culture of free-floating retinal slices: a new system of organotypic cultures of adult rat retina. Ophthalmic Res (2006) 1.42
A single injection of botulinum toxin decreases the margin of safety of neurotransmission at local and distant sites. Anesth Analg (2011) 1.42
Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology. J Immunol (2006) 1.37
The role of lipopolysaccharide-binding protein in modulating the innate immune response. Microbes Infect (2006) 1.32
Bacterial programmed cell death of cerebral endothelial cells involves dual death pathways. J Clin Invest (2005) 1.32
TLR2 mediates neuroinflammation and neuronal damage. J Immunol (2007) 1.26
Timing the valve replacement in infective endocarditis involving the brain. J Neurol (2004) 1.23
Triptans reduce the inflammatory response in bacterial meningitis. J Cereb Blood Flow Metab (2002) 1.20
Dual phases of apoptosis in pneumococcal meningitis. J Infect Dis (2004) 1.11
Neurodegeneration in newborn rats following propofol and sevoflurane anesthesia. Neurotox Res (2009) 1.11
Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. Eur J Neurosci (2002) 1.09
Sugammadex as a reversal agent for neuromuscular block: an evidence-based review. Core Evid (2013) 1.09
Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin 1A receptors. Brain Res Mol Brain Res (2004) 1.08
Pneumolysin causes neuronal cell death through mitochondrial damage. Infect Immun (2007) 1.07
Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state. Proc Natl Acad Sci U S A (2012) 1.07
TRAIL limits excessive host immune responses in bacterial meningitis. J Clin Invest (2007) 1.05
Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke. J Cereb Blood Flow Metab (2010) 1.03
Interplay of pneumococcal hydrogen peroxide and host-derived nitric oxide. Infect Immun (2006) 1.00
Impact of actin filament stabilization on adult hippocampal and olfactory bulb neurogenesis. J Neurosci (2010) 0.99
TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia. J Immunol (2007) 0.97
Fischer 344 and wistar rats differ in anxiety and habituation but not in water maze performance. Neurobiol Learn Mem (2002) 0.94
The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains. Neurosci Lett (2007) 0.93
Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain. J Exp Med (2004) 0.92
Improved reperfusion and neuroprotection by creatine in a mouse model of stroke. J Cereb Blood Flow Metab (2006) 0.92
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in central nervous system inflammation. J Mol Med (Berl) (2009) 0.90
Animal models of the serotonin syndrome: a systematic review. Behav Brain Res (2013) 0.90
Acute effect of ethanol on anxiety and 5-HT in the prefrontal cortex of rats. Alcohol (2002) 0.89
Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis (2010) 0.89
Mice over-expressing the 5-HT(1A) receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT. Behav Brain Res (2005) 0.89
Neuromuscular blockade improves surgical conditions (NISCO). Surg Endosc (2014) 0.89
Inflammation stimulates thrombopoietin (Tpo) expression in rat brain-derived microvascular endothelial cells, but suppresses Tpo in astrocytes and microglia. J Interferon Cytokine Res (2010) 0.85
Serotonin1A receptors in the pathophysiology of schizophrenia: development of novel cognition-enhancing therapeutics. Adv Ther (2008) 0.85
Dysexecutive syndrome after mild cerebral ischemia? Mice learn normally but have deficits in strategy switching. Stroke (2003) 0.85
Accelerated degradation of retinoic acid by activated microglia. J Neuroimmunol (2013) 0.84
Anxiolytic-like profile in Wistar, but not Sprague-Dawley rats in the social interaction test. Psychopharmacology (Berl) (2004) 0.83
Bacterial hydrogen peroxide contributes to cerebral hyperemia during early stages of experimental pneumococcal meningitis. J Cereb Blood Flow Metab (2007) 0.83
Anxiolytic-like effects of kava-kava in the elevated plus maze test--a comparison with diazepam. Prog Neuropsychopharmacol Biol Psychiatry (2002) 0.82
Chronic Escherichia coli infection induces muscle wasting without changing acetylcholine receptor numbers. Intensive Care Med (2007) 0.82
Anxiety as a predictor of alcohol preference in rats? Prog Neuropsychopharmacol Biol Psychiatry (2004) 0.82
Acidosis-induced zinc-dependent death of cultured cerebellar granule neurons. Cell Mol Neurobiol (2010) 0.80
Nitric oxide modulates calcium entry through P/Q-type calcium channels and N-methyl-d-aspartate receptors in rat cortical neurons. Brain Res (2005) 0.80
Antidepressant-like effect of nicotinamide adenine dinucleotide in the forced swim test in rats. Pharmacol Biochem Behav (2004) 0.80
Inducible nitric oxide synthase does not mediate brain damage after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab (2007) 0.79
Assessment of stress in laboratory beagle dogs constrained by a Pavlov sling. ALTEX (2011) 0.79
Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier. Brain Res (2003) 0.79
The use of sudden darkness in mice: a behavioural and pharmacological approach. Psychopharmacology (Berl) (2004) 0.78
The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level. J Neurochem (2004) 0.77
Increasing the number of 5-HT(1A)-receptors in cortex and hippocampus does not induce mnemonic deficits in mice. Pharmacol Biochem Behav (2008) 0.77
Choosing the right wild type: behavioral and neurochemical differences between 2 populations of Sprague-Dawley rats from the same source but maintained at different sites. J Am Assoc Lab Anim Sci (2007) 0.77
Case scenario: residual curarization in diabetic polyneuropathy. Anesthesiology (2014) 0.76
Neuroprotective effects of the beta-carboline abecarnil studied in cultured cortical neurons and organotypic retinal cultures. Neuropharmacology (2007) 0.76
Pharmacokinetic aspects of reduced nicotinamide adenine dinucleotide (NADH) in rats. Front Biosci (2008) 0.76
5-HT(1A)-receptor over-expressing mice: genotype and sex dependent responses to antidepressants in the forced swim-test. Neuropharmacology (2011) 0.76
Cholecystokinin tetrapeptide improves water maze performance of neonatally 6-hydroxydopamine-lesioned young rats. Pharmacol Biochem Behav (2004) 0.76
Bioavailability of reduced nicotinamide-adenine-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy. Pharmacol Toxicol (2002) 0.76
Thrombopoietin contributes to neuronal damage in experimental bacterial meningitis. Infect Immun (2010) 0.76
Treatment with reduced nicotinamide adenine dinucleotide (NADH) improves water maze performance in old Wistar rats. Behav Brain Res (2004) 0.76
Heterogeneous effects of distinct tocopherol analogues on NO release, cell volume, and cell death in microglial cells. J Neurosci Res (2008) 0.75
Brain angiotensin and anxiety-related behavior: the transgenic rat TGR(ASrAOGEN)680. Brain Res (2005) 0.75
Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infect Immun (2004) 0.75
Behavioural and microdialysis study after neurotoxic lesion of the dorsal raphe nucleus in rats. Pharmacol Biochem Behav (2003) 0.75
Continuous administration of pyridostigmine improves immobilization-induced neuromuscular weakness. Crit Care Med (2010) 0.75
Altered nicotinamide adenine dinucleotide (NADH) fluorescence in dt sz mutant hamsters reflects differences in striatal metabolism between severe and mild dystonia. J Neurosci Res (2009) 0.75
Controlled but pragmatic investigations of interventions for behavioural disturbances in dogs and cats. Berl Munch Tierarztl Wochenschr (2011) 0.75
Hypophagic effect of the angiotensin AT1 receptor antagonist irbesartan in rats. Eur J Pharmacol (2007) 0.75
Prolonged administration of pyridostigmine impairs neuromuscular function with and without down-regulation of acetylcholine receptors. Anesthesiology (2013) 0.75
Neuromuscular Recovery Is Prolonged After Immobilization or Superimposition of Inflammation With Immobilization Compared to Inflammation Alone: Data From a Preclinical Model. Crit Care Med (2016) 0.75
Pifithrin-α as a potential cytoprotective agent in radiotherapy: protection of normal tissue without decreasing therapeutic efficacy in glioma cells. Radiat Res (2010) 0.75
Postanaesthesia pulmonary complications after use of muscle relaxants in Europe: Study protocol of the POPULAR study. Eur J Anaesthesiol (2016) 0.75
[History and new developments. The pharmacology of 5-ht3 antagonists]. Pharm Unserer Zeit (2007) 0.75